SAMe 400 mg By Source Naturals Overview & Drug Interactions
Check For Interactions With SAMe 400 mg
Supplement: SAMe 400 mg by Source Naturals
SAMe 400 mg Label Images
This product contains
Below is a list of the 'active' ingredients listed on the supplement label for this product.
For a list of 'other ingredients', such as fillers, please see the 'Label Information' section on this page.
SAMe
S-adenosyl-l-methionine (SAM-e or SAMe) is a compound that is found naturally in the body and is involved in various processes, including the synthesis of neurotransmitters and the metabolism of hormones. SAM-e has been studied as a potential treatment for a variety of health conditions, including depression, osteoarthritis, and liver disease. As a dietary supplement, it is most often used for improving symptoms of depression and for osteoarthritis. In regard to depression, research suggests that SAM-e may be more effective than placebo in reducing the severity of depression and may be as effective as certain antidepressants for some individuals. However, more research is needed. Similarly, for osteoarthritis, some studies show that it is as effective in reducing symptoms for some individuals as NSAIDs (e.g., ibuprofen). There are a variety of different forms of SAM-e supplements available on the market, typically different salt forms (e.g., sulfate, sulfate-p-toluenesulfonate, and butanedisulfonate), which may affect how well it is absorbed.
See More Information Regarding Same| Ingredient Group | SAMe |
|---|---|
| Category | non-nutrient/non-botanical |
-
SAMe Disulfate Tosylate
Description:S-adenosyl-l-methionine (SAM-e or SAMe) is a compound that is found naturally in the body and is involved in various processes, including the synthesis of neurotransmitters and the metabolism of hormones. SAM-e has been studied as a potential treatment for a variety of health conditions, including depression, osteoarthritis, and liver disease. As a dietary supplement, it is most often used for improving symptoms of depression and for osteoarthritis. In regard to depression, research suggests that SAM-e may be more effective than placebo in reducing the severity of depression and may be as effective as certain antidepressants for some individuals. However, more research is needed. Similarly, for osteoarthritis, some studies show that it is as effective in reducing symptoms for some individuals as NSAIDs (e.g., ibuprofen). There are a variety of different forms of SAM-e supplements available on the market, typically different salt forms (e.g., sulfate, sulfate-p-toluenesulfonate, and butanedisulfonate), which may affect how well it is absorbed.
See More Information Regarding Same
Ingredient Group SAMe Category non-nutrient/non-botanical
Drugs that interact with SAMe 400 mg by Source Naturals
Below is a list of drug interactions for each ingredient in this supplement product. Please note that a supplement product may contain more than one ingredient that has interactions.
Label Information
Supplement Facts:
| Daily Value (DV) Target Group(s): | Adults and children 4 or more years of age |
|---|---|
| Minimum serving Sizes: |
1 Tablet(s)
|
| Maximum serving Sizes: |
1 Tablet(s)
|
| Servings per container | 30 |
| Ingredient | Amount per Serving | Group | % DV, Adults & children 4+ years |
|---|---|---|---|
| SAMe |
400 mg
|
SAMe |
--
|
| SAMe Disulfate Tosylate |
800 mg
|
SAMe |
|
| Other Ingredients: |
Cellulose
Methacrylic Acid Copolymer
Mannitol
Citric Acid
Stearic Acid
Silica
Hydroxypropyl Methylcellulose
Triacetin
Sodium Starch Glycolate
modified Cellulose Gum
|
|---|
Label Statments:
| FDA Statement of Identity |
- Dietary Supplement
|
|---|---|
| Formula |
- S-adenosyl-L-methionine 400 mg
- Source Naturals SAMe is a stable, bio-available form of S-adenosyl-L-methionine. These tablets are enteric coated and blister packed for consistent quality and optimal bioactivity. SAMe is present in every living cell in the body and plays an important part in many critical cellular functions.
A number of clinical studies have demonstrated that SAMe supplementation supports joint comfort, function and mobility in the spine, hips and knees. Preliminary research suggests that SAMe may work by supporting the production of proteoglycans, which are important components of cartilage.
Numerous clinical studies have also demonstrated that SAMe can help support a positive outlook. It is able to cross the blood-brain barrier, where it is thought to affect the synthesis of neurotransmitters, and to help maintain normal membrane fluidity. SAMe works together with the B-vitamins, in particular folic acid, making it important to obtain adequate amounts of the B-vitamin complex from diet and supplements.
SAMe plays a key role in transmethylation, a vital type of chemical reaction that affects the synthesis, activation, and metabolism of various biological molecules. Compounds that require this reaction include phospholipids, which are fundamental for all cell membrane functions and for cell to cell communication.
|
| Formulation |
- Improved enteric coating
Supports joint comfort, function and mobility
- Suitable for vegetarians.
- Contains no yeast, dairy, egg, gluten, soy or wheat. Contains no sugar, preservatives, or artificial color, flavor or fragrance.
|
| Suggested/Recommended/Usage/Directions |
- Suggested Use: 1 tablet 1 to 3 times daily. Take tablets on an empty stomach.
|
| Precautions |
- Warning: If you are pregnant, may become pregnant, breastfeeding or are taking antidepressant medication, consult your physician before using this product.
- Use this product under medical supervision if you have bipolar disorder. In a small number of people this product may cause nausea or gastrointestinal upset. If you experience discomfort, discontinue use.
- Do not use if either tamper-evident seal is broken or missing.
- Keep out of the reach of children.
|
| FDA Disclaimer Statement |
- These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
|
| Brand IP Statement(s) |
- Copyright SOURCE NATURALS, INC.
|
Brand Information
| Manufactured for | |
|---|---|
| Name | Source Naturals, Inc. |
| Street Address | P. O. Box 2118 |
| City | Santa Cruz |
| State | CA |
| ZipCode | 95062 |
| Web Address | www.sourcenaturals.com |
Return to the main supplement interaction checker page
Parts of this content are provided by the Therapeutic Research Center, LLC and the Dietary Supplement Label Database.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.