No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 1 of 5 ingredients. Check your meds →
Dietary supplement

Sibb-Zymes Ingredients & Drug Interactions

by Klaire Labs

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Sibb-Zymes is a dietary supplement by Klaire Labs with 5 active ingredients. Its ingredients are commonly taken for lactose intolerance, gas and bloating after dairy, diarrhea from dairy foods.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Sibb-Zymes by Klaire Labs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 5 active ingredients.
  • “Enzyme Blend” is a proprietary blend — the label gives one combined amount (612 mg) without saying how much of each component you get.

Sibb-Zymes contains five active digestive enzymes. Lactase breaks down lactose (milk sugar); glucoamylase and maltase break down starches and their intermediates; sucrase breaks down table sugar; and a protease/peptidase complex breaks down proteins.

The capsule itself is made from hydroxypropyl methylcellulose, with water and microcrystalline cellulose as inactive ingredients.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: enzyme supplement for digestive support.
  • We looked for evidence on: Lactose intolerance, gas and bloating, digestive discomfort, dairy intolerance.
  • The strongest evidence on file: Lactase is rated "Effective" for Lactose intolerance (Natural Medicines).

Lactase is effective for lactose intolerance — the inability to digest milk sugar. The data we have isn't sufficient to rate lactase for prematurity or colic.

We don't hold effectiveness ratings for the other four enzymes in this product.

The evidence, ingredient by ingredient Lactase

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactase is generally well tolerated when used as directed. A rare case of contact dermatitis and allergic rhinoconjunctivitis has been reported in a worker exposed to powdered lactase; if you have a known lactase allergy, this product isn't for you.

For pregnancy, the data suggests lactase is likely safe, but check with your doctor first. We don't have pregnancy or breastfeeding safety data on file for the other enzymes — talk with your doctor or pharmacist before regular use in pregnancy if you're concerned.

Side effects, ingredient by ingredient Lactase

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. Still, run your medications through the search tool on this page — we don't hold data for several of the enzymes in this blend.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Sibb-Zymes is a good fit if you have trouble digesting lactose or want broader enzyme support with meals. If you're pregnant or breastfeeding, or if you have a known enzyme allergy, check with your pharmacist first.

No drug interactions are documented for the one ingredient we could fully review.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 21, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Sibb-Zymes, straight from the product label.

Brand Klaire Labs
Barcode (UPC) 709616310045
Net contents 180 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Dec 21, 2024
DSLD ID 322456
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Sibb-Zymes by Klaire Labs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
90
UPC/BARCODE
709616310045
IngredientAmount% DV
Lactase0 NP--
Glucoamylase0 NP--
Maltase0 NP--
Enzyme Blend612 mg--
Sucrase0 NP--
Protease/Peptidase Complex0 NP--

Other ingredients: Hydroxypropyl Methylcellulose, Water, Microcrystalline Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Units are those used in the Food Chemicals Codex (FCC).

SFI

Formulation

Free of the following common allergens: milk/casein, eggs, fish, shellfish, tree nuts, and peanuts. Contains no artificial colors, flavors or preservatives.

Produced under a strict quality management system in compliance with Good Manufacturing Practices (GMPs) and third-party quality certifications.

Suggested/Recommended/Usage/Directions

Suggested Use: 2 capsules at the beginning of each meal or as directed by a healthcare professional.

Precautions

Do not use if shrinkwrap is broken or missing.

Caution: If you are pregnant, nursing, have a medical condition, or taking prescription drugs, consult your physician before using this product.

Keep out of reach of children.

Storage

Store in a cool, dry place (59 Degrees F - 85 Degrees F) away from direct light.

FDA Statement of Identity

Enzyme Supplement

See for yourself

Sibb-Zymes by Klaire Labs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Sibb-Zymes by Klaire Labs

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Enzyme Blend

612 mg per serving
  • Lactase
  • › Glucoamylase
  • › Maltase
  • › Sucrase
  • › Protease/Peptidase Complex

Other (inactive) ingredients: Hydroxypropyl Methylcellulose, Water, Microcrystalline Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Sibb-Zymes by Klaire Labs Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Sibb-Zymes. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Sibb-Zymes, from the product label.

Klaire Labs

See all Klaire Labs products
Name
SFI USA
City
Reno
State
NV
ZipCode
89521
Web Address
Klaire.com
Pharmacist Counseling Corner

Sibb-Zymes by Klaire Labs: Common Questions

Does Sibb-Zymes by Klaire Labs interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Sibb-Zymes. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Sibb-Zymes contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will Sibb-Zymes help with my lactose intolerance?
Yes — lactase, the main ingredient, is effective for lactose intolerance. It breaks down the milk sugar your body can't digest on its own.
Does it have any fillers?
The capsule contains hydroxypropyl methylcellulose, plus water and microcrystalline cellulose. Those are inactive ingredients — the five enzymes are the active ones.
Can I take this while pregnant?
The data suggests lactase is likely safe in pregnancy, but there isn't enough information on the other enzymes. Talk with your doctor or pharmacist before starting regular use.
What are these enzymes supposed to do?
They help break down carbohydrates and proteins in your food. Lactase handles milk sugar, glucoamylase and maltase handle starches, sucrase handles table sugar, and the protease/peptidase complex breaks down proteins.
Could I be allergic to this?
True allergy to lactase is rare, but it has happened — usually in people exposed to powdered lactase. If you suspect an enzyme allergy, talk to your pharmacist before taking it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Sibb-Zymes is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Sibb-Zymes label
Go deeper

The Full Monographs Behind Sibb-Zymes’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Sibb-Zymes's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 1 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactase 1 reference
  1. Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed

See these in context on the Lactase monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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