Similase BV Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Similase BV against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Similase BV is a dietary supplement by Integrative Therapeutics with 9 active ingredients. Its ingredients are commonly taken for improving mineral absorption, breaking down phytic acid (phytate) in grains and legumes, supporting digestion of plant-based foods.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Similase BV by Integrative Therapeutics
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Similase BV contains 9 active enzyme ingredients designed to support digestion. The formula includes Amylase (breaks down carbohydrates), Protease (breaks down protein), and Lipase (breaks down fat), plus Lactase for lactose digestion and several others — Phytase, Alpha-Galactosidase, Sucrase, Cellulase, and Maltase — that target different food components.
These are delivered in a vegetable capsule with inactive ingredients including cellulose and ascorbyl palmitate.
Does it work?
Strong evidence
The evidence on these enzymes is mixed. Lactase is effective for lactose intolerance — that one's well established.
For the others — Phytase, Protease, and Lipase — the science we hold isn't strong enough to rate them. They carry ratings of insufficient reliable evidence for conditions like inflammatory bowel disease, dyspepsia, and various deficiencies.
If you're looking for help with specific digestion or nutrient absorption, talk with your doctor or pharmacist about what the current evidence shows for your particular situation.
How safe is it?
Well-documented data
Most of these enzymes are generally well tolerated when taken by mouth. The main caution is that Phytase and Protease come with rare but real reports of allergic reactions — including occupational asthma and hypersensitivity pneumonitis — from airborne powder exposure in workers.
For Lactase, one case of allergic contact dermatitis has been reported. If you have a serious digestive condition, check with your doctor before starting.
Lipase is generally well tolerated, though a thorough safety evaluation hasn't been done. During pregnancy or while breastfeeding, the data on these supplemental enzymes is limited; talk with your doctor or pharmacist for personalized guidance.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredients we could check. Still, use the search tool on this page to look up your specific medications before starting Similase BV.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
Similase BV is an enzyme supplement that may help with digestion, and the enzymes are generally well tolerated. Lactase is proven effective for lactose intolerance; the others lack strong evidence for their intended uses.
No drug interactions are documented for the ingredients we could check, but if you take medications, confirm your specific drugs on this page first. Pregnancy, breastfeeding, or serious digestive conditions warrant a conversation with your own doctor or pharmacist before you start.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 4 of 9 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 21, 2017.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Similase BV, straight from the product label.
| Brand | Integrative Therapeutics |
|---|---|
| Barcode (UPC) | 871791000919 |
| Net contents | 90 Veg Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Sep 21, 2017 |
| DSLD ID | 78469 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Similase BV by Integrative Therapeutics, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Amylase | 0 NP | -- |
| Alpha-Galactosidase | 0 NP | -- |
| Phytase | 0 NP | -- |
| Protease | 0 NP | -- |
| Lipase | 0 NP | -- |
| Sucrase | 0 NP | -- |
| Lactase | 0 NP | -- |
| Cellulase | 0 NP | -- |
| Maltase | 0 NP | -- |
| Microbial Enzymes | 626 mg | -- |
Other ingredients: Vegetable Capsule, Cellulose, Ascorbyl Palmitate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Contains no sugar, salt, yeast, wheat, corn, soy, dairy products, artificial coloring, artificial flavoring, preservatives, or ingredients of animal origin.
Brand IP Statement(s)
2014 Distributed by Integrative Therapeutics, LLC
General
LZ106001.C01 (B060100C)
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
General Statements
Bean and vegetable digestive enzymes
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Recommendations: Take 1 or 2 capsules at the beginning of each meal, or as recommended by your healthcare professional.
Precautions
Not recommended for use if peptic ulcer, gastritis, or heartburn is present.
If pregnant, nursing, or taking prescription drugs, consult your healthcare professional prior to use.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Similase BV by Integrative Therapeutics label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Similase BV by Integrative Therapeutics
These are the 9 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container45 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Other (inactive) ingredients: Vegetable Capsule, Cellulose, Ascorbyl Palmitate. These complete the product’s ingredient list but are not active constituents.
Similase BV by Integrative Therapeutics Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Similase BV. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Similase BV, from the product label.
Integrative Therapeutics
See all Integrative Therapeutics products- Name
- Integrative Therapeutics, LLC
- City
- Green Bay
- State
- WI
- ZipCode
- 54311
- Phone Number
- 800.931.1709
- Web Address
- integrativepro.com
Similase BV by Integrative Therapeutics: Common Questions
Does Similase BV by Integrative Therapeutics interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will Similase BV help with my lactose intolerance?
Is it safe to take this while I'm pregnant?
Can I take this while breastfeeding?
What do all these enzymes do?
Has anyone reported side effects from these enzymes?
Do I need to avoid this if I have digestive problems?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Similase BV is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Similase BV’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Phytase
Phytase is an enzyme that breaks down phytic acid (phytate) found in grains, beans, nuts, and seeds, which can free up minerals like iron, zinc, and calcium for absorption. It is widely used...
Read the full Phytase monograph → Herb & supplement monographProteolytic Enzymes (proteases)
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), trypsin, chymotrypsin, and pancreatin. Peo...
Read the full Proteolytic Enzymes (proteases) monograph → Herb & supplement monographLipase
Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy for people who cannot make enough of their...
Read the full Lipase monograph → Herb & supplement monographLactase
Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can reduce gas, bloating, cramping, and diarrhe...
Read the full Lactase monograph →Sources & How We Checked
Similase BV's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 12 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Phytase 7 references
- Lei XG, Weaver JD, Mullaney E, Ullah AH, Azain MJ. Phytase, a new life for an "old" enzyme. Annu Rev Anim Biosci. 2013;1:283-309. PubMed
- Smuts CM, Matsungo TM, Malan L, et al. Effect of small-quantity lipid-based nutrient supplements on growth, psychomotor development, iron status, and morbidity among 6- to 12-mo-old infants in South Africa: a randomized controlled trial. Am J Clin Nutr. 2 PubMed
- van Heemst RC, Sander I, Rooyackers J, et al. Hypersensitivity pneumonitis caused by occupational exposure to phytase. Eur Respir J. 2009;33(6):1507-9. PubMed
- Baur X, Melching-Kollmuss S, Koops F, Strassburger K, Zober A. IgE-mediated allergy to phytase -- a new animal feed additive. Allergy. 2002;57(10):943-5. PubMed
- Doekes G, Kamminga N, Helwegen L, Heederik D. Occupational IgE sensitisation to phytase, a phosphatase derived from Aspergillus niger. Occup Environ Med. 1999;56(7):454-9. PubMed
- Brnic M, Hurrell RF, Songré-Ouattara LT, et al. Effect of phytase on zinc absorption from a millet-based porridge fed to young Burkinabe children. Eur J Clin Nutr. 2017;71(1):137-141. PubMed
- Koshy JC, Sharabi SE, Feldman EM, Hollier LH Jr, Patrinely JR, Soparkar CN. Effect of dietary zinc and phytase supplementation on botulinum toxin treatments. J Drugs Dermatol. 2012;11(4):507-12.
Proteolytic Enzymes (proteases) 3 references
- Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
- Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
- Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed
See these in context on the Proteolytic Enzymes (proteases) monograph →
Lipase 1 reference
- Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed
Lactase 1 reference
- Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC