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Dietary supplement

Slippery Elm Bark Ingredients & Drug Interactions

by Dr. Clark Store

Slippery Elm Bark label
See full label image
Powder Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Slippery Elm Bark against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Slippery Elm Bark is a dietary supplement by Dr. Clark Store with 1 active ingredient. Its ingredients are commonly taken for sore throat and cough, heartburn and acid reflux, digestive upset and ibs.Based on those ingredients, 2,022 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Slippery Elm bark (Ulmus fulva) powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Slippery Elm Bark by Dr. Clark Store

Ask about any prescription or over-the-counter medication and we check it for interactions with Slippery Elm Bark by Dr. Clark Store — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Slippery Elm Bark by Dr. Clark Store

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Slippery Elm bark powder from the Ulmus fulva tree. The inner bark of slippery elm is traditionally used because it's rich in mucilage — a protective, soothing substance.

There are no inactive ingredients listed in this formulation.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Slippery Elm product and its label doesn't state a use — see Slippery Elm's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for slippery elm is limited. We don't have reliable data to rate whether it works for constipation, diarrhea, cough, inflammatory bowel disease (a chronic swelling of the digestive tract), or cancer.

While people have used it for generations, the scientific studies strong enough to prove benefit aren't in our data.

The evidence, ingredient by ingredient Slippery Elm

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Slippery elm is generally well tolerated for short-term use, but high-quality safety data are limited, so we don't know as much about long-term safety as we'd like. The pollen and direct contact with slippery elm can trigger allergic reactions — contact dermatitis (itchy, inflamed skin) and urticaria (hives) have been reported.

There isn't enough reliable safety data to know whether it's safe during pregnancy or while breastfeeding, so caution is advised in both cases.

Side effects, ingredient by ingredient Slippery Elm

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Slippery Elm.
  • The most serious interaction on file is rated Moderate.
  • For scale: 2,023 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take Slippery Elm Bark, check all the oral medications you're taking — anything you swallow as a pill, tablet, capsule, or liquid. The mucilage in slippery elm may slow their absorption and lower how much reaches your bloodstream, potentially making them less effective.

Your doctor or pharmacist can help you decide whether to use it and how to space doses safely.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Slippery Elm Bark is a single-ingredient product used traditionally to soothe the digestive tract, but scientific evidence for its effectiveness isn't established in our data. The main caution is that it may slow how your body absorbs oral medications — a concern affecting many drug types.

Check your exact medications with the tool on this page, and talk it over with your doctor or pharmacist before starting, especially if you take regular prescriptions or are pregnant or breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 22, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Slippery Elm Bark, straight from the product label.

Brand Dr. Clark Store
Barcode (UPC) 652384105354
Net contents 1 Cup(s)
Market status On market
Date entered into DSLD May 22, 2020
DSLD ID 220957
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Slippery Elm Bark by Dr. Clark Store, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tbsp
Maximum serving Sizes:
1 Tbsp
Servings per container
16
UPC/BARCODE
652384105354
IngredientAmount% DV
Slippery Elm bark (Ulmus fulva) powder3.75 gm--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Leader in purity Established by Dr. Clark's Family in 1993

Seals/Symbols

GMP Quality Assured

Made in USA

Suggested/Recommended/Usage/Directions

Suggested Use: Take 1 level tablespoon mixed into a beverage twice a day, or as directed by a healthcare professional.

Precautions

Warning: If you are pregnant, nursing, or taking any medications, consult your doctor before use.

If any adverse reactions occur, immediately stop using this product and consult your doctor.

Keep away from children.

Storage

Store at room temperature.

Formulation

Our products don't contain flow agents like magnesium stearate. Not now, not ever.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Slippery Elm Bark by Dr. Clark Store label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Slippery Elm Bark label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Slippery Elm Bark by Dr. Clark Store

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tbsp Dosage formPowder Servings per container16 Amounts shown are per serving.

Slippery Elm bark (Ulmus fulva) powder

Interacts with
2,022 drugs
3.75 gm per serving

Slippery elm is a traditional herbal remedy made from the inner bark of a North American elm tree, used mainly to soothe sore throats and irritated di...

Slippery Elm bark (Ulmus fulva) powder monograph & interactions
Interaction report

Slippery Elm Bark by Dr. Clark Store Drug Interactions

Want to check YOUR meds against Slippery Elm Bark?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,022Drugs
2,022 Moderate

Ingredients driving the most interactions

Slippery Elm bark (Ulmus fulva) powder 2,022

Individual Drug Interactions

The ingredients in Slippery Elm Bark interact with 2,022 drugs. Click any drug to see the details.

1 of the 1 ingredient in Slippery Elm Bark interact with drugs. Each result below shows which ingredient is responsible. Slippery Elm bark (Ulmus fulva) powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Slippery Elm Bark with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Slippery Elm bark (Ulmus fulva) powder1 drug type · 2,022 drugs

Oral Drugs

Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Slippery elm inner bark contains mucilage, which may interfere with the absorption of orally administered drugs.

Likelihood Possible Evidence D
Slippery Elm bark (Ulmus fulva) powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Slippery Elm Bark, from the product label.

Dr. Clark Store

See all Dr. Clark Store products
Name
Dr. Clark Store
Phone Number
(866) 372-5275
Web Address
www.DrClarkStore.com
Pharmacist Counseling Corner

Slippery Elm Bark by Dr. Clark Store: Common Questions

Does Slippery Elm Bark by Dr. Clark Store interact with any medications?
Yes. Based on its ingredients, Slippery Elm Bark has a known interaction with 2,022 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Slippery Elm Bark contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take slippery elm if I'm on other medications?
Possibly, but you need to check first. Slippery elm may slow how your body absorbs oral drugs and lower their levels in your blood, which could make them less effective. Use the medication checker on this page to search your drugs, then talk with your doctor or pharmacist about whether it's safe for you and whether you need to space out doses.
Is slippery elm safe during pregnancy or breastfeeding?
There isn't enough reliable data to say either way. Some sources caution against using it in pregnancy, and there's too little information on safety while breastfeeding. Talk with your doctor or pharmacist about whether it's right for you in these situations.
Can slippery elm cause allergic reactions?
Yes. The pollen is an allergen, and direct contact with the bark or powder can trigger contact dermatitis (itchy, inflamed skin) or urticaria (hives). If you have a history of plant allergies or sensitive skin, mention this product to your doctor or pharmacist before using it.
How long is it safe to use slippery elm?
It's generally well tolerated for short-term use, but we don't have strong safety data for long-term use. If you're thinking of using it beyond a few weeks, check with your pharmacist or doctor.
Does slippery elm actually work for constipation or diarrhea?
The evidence is insufficient — we don't have reliable data to say it works for either. While people have used it traditionally for digestive complaints, the studies strong enough to prove benefit aren't in our data.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Slippery Elm Bark is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Slippery Elm Bark label
Go deeper

The Full Monographs Behind Slippery Elm Bark’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Slippery Elm

Interacts with 2,022 drugs

Slippery elm is a traditional herbal remedy made from the inner bark of a North American elm tree, used mainly to soothe sore throats and irritated digestive tracts. Its mucilage can coat an...

Read the full Slippery Elm monograph →
Sources

Sources & How We Checked

Slippery Elm Bark's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Slippery Elm 3 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  3. Czarnecki D, Nixon R, Bekhor P, and et al. Delayed prolonged contact urticaria from the elm tree. Contact Dermatitis 1993;28:196-197. PubMed

See these in context on the Slippery Elm monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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