SpectraZyme Complete Ingredients & Drug Interactions
by Metagenics
What is this page for?
First and foremost: checking SpectraZyme Complete against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
SpectraZyme Complete is a dietary supplement by Metagenics with 11 active ingredients. Its ingredients are commonly taken for digestive support, bloating and gas, fat digestion.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of SpectraZyme Complete by Metagenics
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
SpectraZyme Complete contains 11 active digestive enzymes: Amylase (breaks down starches), Lipase (breaks down fats), Lactase (breaks down milk sugar), Cellulase, Invertase, Xylanase, Pectinase, Acid Protease, Hemicellulase, Protease (Fungal), and Neutral Protease—the last group all break down proteins in various ways. The capsule also contains inactive ingredients: Maltodextrin and Medium-Chain Triglycerides (plus the capsule itself).
Does it work?
Strong evidence
The evidence on these enzymes is mixed and often limited. Lactase is effective for lactose intolerance.
For Lipase and most other enzymes in this formula—including their use in inflammatory bowel disease (IBD), dyspepsia (indigestion), and other conditions—the evidence we have isn't enough to say whether they work. No effectiveness data is on file for the protease forms.
How safe is it?
Well-documented data
The enzymes in this blend are generally well tolerated by most adults, though digestive upset or allergic reactions are possible. Lactase has been associated with rare allergic reactions in people exposed to the powdered form, and proteases can occasionally trigger allergic responses in people with occupational exposure.
For pregnancy, the data is thin: Lactase is likely safe, but the safety data on Lipase and the proteases during pregnancy hasn't been well established—use only if your doctor advises it. For breastfeeding, limited safety data exists for Lipase and the proteases; check with your healthcare provider first.
People with serious digestive conditions should use Lipase only under medical guidance.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredients we could check. If you take any medications, confirm with your own doctor or pharmacist that this product won't interfere with them.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
This is a broad-spectrum digestive enzyme supplement aimed at people with mild digestion concerns. Lactase will help if you're lactose intolerant; for the others, the evidence is incomplete.
No drug interactions are documented for the ingredients we checked. If you're pregnant, breastfeeding, or have a serious digestive condition, talk with your doctor or pharmacist before starting.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 5 of 11 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 24, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about SpectraZyme Complete, straight from the product label.
| Brand | Metagenics |
|---|---|
| Barcode (UPC) | 755571939197 |
| Net contents | 180 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Mar 24, 2020 |
| DSLD ID | 216261 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for SpectraZyme Complete by Metagenics, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Amylase | 0 NP | -- |
| Lipase | 0 NP | -- |
| Lactase | 0 NP | -- |
| Cellulase | 0 NP | -- |
| Invertase | 0 NP | -- |
| Xylanase | 0 NP | -- |
| Pectinase | 0 NP | -- |
| Acid Protease | 0 NP | -- |
| Hemicellulase | 0 NP | -- |
| Protease, Fungal | 0 NP | -- |
| Neutral Protease | 0 NP | -- |
| Proprietary Complete Enzyme Blend | 271 mg | -- |
Other ingredients: Capsule, Maltodextrin, Medium-Chain Triglycerides
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
SpectraZyme Complete provides digestive support with a non-GMO, broad spectrum of non-animal derived enzymes including acid stable lipase and three proteases that function in different pH ranges.
Formulation
This comprehensive enzyme complex is designed to support the healthy digestion of proteins, peptides, carbohydrates, fats, cellulose, maltose, lactose, and sucrose.
This product is non-GMO.
Broad spectrum digestive support
Suggested/Recommended/Usage/Directions
Directions: Take 2 capsules with each meal or as directed by your healthcare practitioner.
Precautions
Caution: If taking anti-diabetic medications, please consult your healthcare practitioner before use.
Tamper Evident: Do not use if safety seal is missing or broken.
Contains: Milk, wheat, and soy
Storage
Storage: Keep tightly closed in a cool, dry place.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
FDA Statement of Identity
Dietary Supplement
General Statements
Practitioner exclusive
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
SpectraZyme Complete by Metagenics label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in SpectraZyme Complete by Metagenics
These are the 11 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Complete Enzyme Blend
- › Amylase
- › Lipase
- › Lactase
- › Cellulase
- › Invertase
- › Xylanase
- › Pectinase
- › Acid Protease
- › Hemicellulase
- › Protease, Fungal
- › Neutral Protease
Other (inactive) ingredients: Capsule, Maltodextrin, Medium-Chain Triglycerides. These complete the product’s ingredient list but are not active constituents.
SpectraZyme Complete by Metagenics Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in SpectraZyme Complete. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for SpectraZyme Complete, from the product label.
Metagenics
See all Metagenics products- Name
- Metagenics
- City
- Gig Harbor
- State
- WA
- ZipCode
- 98332
- Phone Number
- 800 692 9400
- Web Address
- metagenics.com
SpectraZyme Complete by Metagenics: Common Questions
Does SpectraZyme Complete by Metagenics interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will this help my digestive problems?
Can I take this while I'm pregnant?
Is this safe while breastfeeding?
Can I be allergic to these enzymes?
What's in the capsule besides the enzymes?
Is this safe if I have a serious digestive condition?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if SpectraZyme Complete is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind SpectraZyme Complete’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Lipase
Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy for people who cannot make enough of their...
Read the full Lipase monograph → Herb & supplement monographLactase
Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can reduce gas, bloating, cramping, and diarrhe...
Read the full Lactase monograph → Herb & supplement monographProteolytic Enzymes (proteases)
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), trypsin, chymotrypsin, and pancreatin. Peo...
Read the full Proteolytic Enzymes (proteases) monograph →Sources & How We Checked
SpectraZyme Complete's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 5 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Lipase 1 reference
- Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed
Lactase 1 reference
- Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed
Proteolytic Enzymes (proteases) 3 references
- Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
- Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
- Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed
See these in context on the Proteolytic Enzymes (proteases) monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC