SpectraZyme Pan 9x ES Ingredients & Drug Interactions
by Metagenics
What is this page for?
First and foremost: checking SpectraZyme Pan 9x ES against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
SpectraZyme Pan 9x ES is a dietary supplement by Metagenics with 3 active ingredients. Its ingredients are commonly taken for digestive support, bloating and gas, fat digestion.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of SpectraZyme Pan 9x ES by Metagenics
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
SpectraZyme Pan 9x ES is a 3-ingredient enzyme blend designed to support digestion. Lipase breaks down fats, protease breaks down proteins, and amylase breaks down carbohydrates — together they mimic the work of your pancreas.
The product also contains a porcine pancreatic concentrate (an animal-derived source of these same enzymes) and several inactive ingredients that serve as fillers and binders.
Does it work?
No specific claim
The evidence on these individual enzymes for digestive complaints is not established. For lipase, studies are insufficient to rate whether it works for inflammatory bowel disease or dyspepsia (upset stomach).
We hold no effectiveness ratings for protease or amylase in our data. If you're considering this product for a specific digestive condition, talk to your pharmacist or doctor about what the evidence actually supports.
How safe is it?
Well-documented data
Lipase and protease are generally well tolerated in adults, though protease may occasionally cause digestive upset or allergic reactions — rarely, occupational exposure to protease has triggered allergic rhinitis or asthma in sensitive people. There is little safety data on lipase or protease during pregnancy or breastfeeding; if you're pregnant or nursing, check with your doctor before starting.
People with serious digestive conditions should use lipase only under medical guidance. Safety data for amylase during pregnancy and breastfeeding is not on file.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredients we could check — lipase and protease have no known drug interactions. Amylase was not checked.
Still, run your exact medications through the search tool below before you begin, so we can catch anything our data might have missed.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure marketed for general wellness rather than one specific gradeable purpose. No medication interactions are currently documented, and safety information is well characterized.
This is a straightforward digestive enzyme blend for people looking to support their digestion with pancreatic enzymes. If you're pregnant, nursing, or have a serious digestive condition, talk to your doctor first.
Check your medications with the tool on this page before you start.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about SpectraZyme Pan 9x ES, straight from the product label.
| Brand | Metagenics |
|---|---|
| Barcode (UPC) | 755571939647 |
| Net contents | 90 Tablet(s) |
| Market status | On market |
| Date entered into DSLD | Aug 23, 2023 |
| DSLD ID | 295864 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for SpectraZyme Pan 9x ES by Metagenics, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Lipase | 0 NP | -- |
| Protease | 0 NP | -- |
| Amylase | 0 NP | -- |
| Pancreatin | 720 mg | -- |
Other ingredients: Porcine Pancreatic concentrate, Microcrystalline Cellulose, Croscarmellose Sodium, Sodium Starch Glycolate, Stearic Acid, Silica
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
SpectraZyme Pan 9x ES is a comprehensive enzyme complex that provides support for digestive function. The porcine pancreatic concentrate is processed under special conditions so that the delicate enzyme constituents remain intact. Provides twice the digestive enzyme strength of regular Pan 9x.
This product is non-GMO and gluten-free.
Certified Gluten Free GFCO.org (Gluten-Free Certification Organization)
Suggested/Recommended/Usage/Directions
Directions: Take one tablet with each meal or as directed by your health care practitioner.
Precautions
Caution: Do not use if there is a prior history of or a current peptic or duodenal ulcer.
Do not use in individuals who have a known allergy or hypersensitivity to pork protein.
Consult your healthcare practitioner if taking other nutritional supplements or medications.
Keep out of the reach of children.
Practitioner Exclusive
Seals/Symbols
Certified Gluten Free GFCO.org (Gluten-Free Certification Organization)
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Formula
Bioactive pancreatic enzymes for digestive support
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
SpectraZyme Pan 9x ES by Metagenics label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in SpectraZyme Pan 9x ES by Metagenics
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container90 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Other (inactive) ingredients: Porcine Pancreatic concentrate, Microcrystalline Cellulose, Croscarmellose Sodium, Sodium Starch Glycolate, Stearic Acid, Silica. These complete the product’s ingredient list but are not active constituents.
SpectraZyme Pan 9x ES by Metagenics Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in SpectraZyme Pan 9x ES. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for SpectraZyme Pan 9x ES, from the product label.
Metagenics
See all Metagenics products- Name
- Metagenics
- City
- Gig Harbor
- State
- WA
- ZipCode
- 98332
- Phone Number
- 800 692 9400
- Web Address
- metagenics.com
SpectraZyme Pan 9x ES by Metagenics: Common Questions
Does SpectraZyme Pan 9x ES by Metagenics interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What does each enzyme in this product do?
Is it safe to take while pregnant?
Can I take it while breastfeeding?
What are the side effects?
Is this safe if I have a digestive disorder?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if SpectraZyme Pan 9x ES is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind SpectraZyme Pan 9x ES’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Lipase
Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy for people who cannot make enough of their...
Read the full Lipase monograph → Herb & supplement monographProteolytic Enzymes (proteases)
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), trypsin, chymotrypsin, and pancreatin. Peo...
Read the full Proteolytic Enzymes (proteases) monograph →Sources & How We Checked
SpectraZyme Pan 9x ES's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 4 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Lipase 1 reference
- Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed
Proteolytic Enzymes (proteases) 3 references
- Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
- Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
- Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed
See these in context on the Proteolytic Enzymes (proteases) monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC