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Maca is a root vegetable native to the Andes region of South America and is rich in nutrients, including vitamins, minerals, and amino acids. It is also a good source of fiber. Maca has been used in traditional medicine to improve energy, stamina, and sexual function. It is also purported to help to improve mood, reduce anxiety, and reduce the symptoms of menopause. Dietary supplements containing maca utilize the root of the plant and are sometimes standardized for two types of compounds found in it, macaenes and macamides.

Eurycoma longifolia, also known as tongkat ali or "Malaysian ginseng," is a plant native to Southeast Asia. It is a member of the Simaroubaceae family and is known for its small, yellow flowers and elongated, slender leaves. It has a long history of use in traditional medicine and is thought to have anti-inflammatory and pain-relieving effects. Eurycoma longifolia is also purported to have a number of other medicinal properties, including the ability to improve immune function, reduce the risk of heart disease, and lower cholesterol levels. Additionally, Eurycoma longifolia is commonly used as a natural treatment for male infertility and as a natural performance-enhancing supplement as it may have a mild androgenic effect. When used for male enhancement, it is most often marketed under other common names for the plant (e.g., tongkat ali, longjack).

Saw palmetto (Serenoa repens) is a plant native to the southeastern United States and a member of the Arecaceae family. It is a small, palm-like tree with fan-shaped leaves that produces small, white flowers. The fruit of the plant is a small, dark purple berry, which is what is used in dietary supplements. In traditional medicine, saw palmetto has been used to treat a variety of health conditions, including prostate problems (such as BPH [benign prostatic hyperplasia]) and urinary tract disorders. It is also claimed to have anti-inflammatory and antioxidant properties and to improve hair growth.