No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 4 of 16 ingredients. Check your meds →
Dietary supplement

Sugar/Starch DigestEnz Ingredients & Drug Interactions

by ProEnzol

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Sugar/Starch DigestEnz is a dietary supplement by ProEnzol with 16 active ingredients. Its ingredients are commonly taken for digestion and bloating, muscle soreness and exercise recovery, inflammation and swelling.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Sugar/Starch DigestEnz by ProEnzol

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 16 active ingredients.
  • “Sugar/Starch DigestEnz Blend” is a proprietary blend — the label gives one combined amount (275 mg) without saying how much of each component you get.

This product contains 16 active ingredients, all digestive enzymes designed to break down different food components. Protease breaks down proteins; lipase handles fats; lactase splits lactose (milk sugar); and the rest target starches, fiber, and other carbohydrates.

They're meant to work together to improve how your body digests food. The product also contains plant fiber and water as inactive ingredients.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: assist digestion of high carbohydrate foods.
  • We looked for evidence on: Dyspepsia, Lactose intolerance, bloating, gas, carbohydrate intolerance.
  • The strongest evidence on file: Lactase is rated "Effective" for Lactose intolerance (Natural Medicines).
  • Also on file: Lipase is rated "Insufficient Reliable Evidence To Rate" for Dyspepsia.

Lactase in this blend is effective for lactose intolerance — that's well established. For the other enzymes, the evidence we hold isn't strong enough to rate them.

Lipase and phytase show insufficient reliable evidence for the digestive and nutritional uses they're often marketed for, like inflammatory bowel disease or iron absorption. Protease and the rest don't have effectiveness ratings in our data.

The evidence, ingredient by ingredient Proteolytic Enzymes (proteases) Lipase Lactase Phytase

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

These enzymes are generally well tolerated in adults when taken as directed. Protease and lipase may occasionally cause digestive upset, and rare allergic reactions have been reported in people exposed to powdered enzyme products — though your supplement dose is much lower than occupational exposures.

Lactase is generally well tolerated. During pregnancy, the safety data is limited for most of these ingredients; lipase and protease are best avoided unless your doctor advises otherwise.

For breastfeeding, there's little data on any of them, so check with your doctor or pharmacist first. Phytase safety in supplements hasn't been well studied either.

Side effects, ingredient by ingredient Proteolytic Enzymes (proteases) Lipase Lactase Phytase

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 4 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. Run your medications through the tool on this page to confirm.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

If you have lactose intolerance, lactase in this blend can help. For other digestive concerns, the evidence for the other enzymes isn't clear.

This product is generally well tolerated, but talk with your pharmacist if you're pregnant, breastfeeding, or have a serious digestive condition like inflammatory bowel disease.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 16 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Sugar/Starch DigestEnz, straight from the product label.

Brand ProEnzol
Barcode (UPC) 707636125618
Net contents 90 Vegan Capsule(s)
Market status On market
Date entered into DSLD Nov 22, 2024
DSLD ID 322883
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Sugar/Starch DigestEnz by ProEnzol, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Vegan Capsule(s)
Maximum serving Sizes:
1 Vegan Capsule(s)
Servings per container
90
UPC/BARCODE
707636125618
IngredientAmount% DV
Amylase0 NP--
Protease0 NP--
Lipase0 NP--
Lactase0 NP--
Cellulase0 NP--
Peptidase0 NP--
Invertase0 NP--
Glucoamylase0 NP--
Xylanase0 NP--
Pectinase0 NP--
Maltase0 NP--
Beta-Glucanase0 NP--
Phytase0 NP--
Hemicellulase0 NP--
Diastase0 NP--
Alpha-Galactosidase0 NP--
Sugar/Starch DigestEnz Blend275 mg--

Other ingredients: Plant Fiber, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

ProEnzol Sugar/Starch DigestEnz provides a blend of non-animal derived enzymes with extra Invertase, Amylase and Diatase to assist the body's own enzymes in the digestion of foods in high carbohydrates helping to relieve occasional gastrointestinal discomfort.

Suggested/Recommended/Usage/Directions

Directions: Take one (1) capsule at the beginning of any meal or snack containing sugar/starch, or as directed by your healthcare professional.

Precautions

Caution: If you are pregnant, nursing, have a serious medical condition, or take any medications, consult your healthcare professional before use.

Use only if tamper-evident seal is unbroken.

Keep out of reach of children.

Exclusively for professionals

Storage

Store tightly closed in a cool, dry place.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

Helps digest foods high in simple and complex carbohydrates

Contains no: Sugar, soy, wheat, yeast, gluten, peanuts, tree nuts, eggs, dairy, animal products, artificial colors, flavors and sweeteners or genetically modified organisms (GMOs).

FDA Statement of Identity

Dietary Supplement

See for yourself

Sugar/Starch DigestEnz by ProEnzol label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Sugar/Starch DigestEnz by ProEnzol

These are the 16 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Vegan Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sugar/Starch DigestEnz Blend

275 mg per serving
  • › Amylase
  • Protease
  • Lipase
  • Lactase
  • › Cellulase
  • › Peptidase
  • › Invertase
  • › Glucoamylase
  • › Xylanase
  • › Pectinase
  • › Maltase
  • › Beta-Glucanase
  • Phytase
  • › Hemicellulase
  • › Diastase
  • › Alpha-Galactosidase

Other (inactive) ingredients: Plant Fiber, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Sugar/Starch DigestEnz by ProEnzol Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Sugar/Starch DigestEnz. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Sugar/Starch DigestEnz, from the product label.

ProEnzol

See all ProEnzol products
Name
Enzymes Inc.
City
Kansas City
State
MO
ZipCode
64153
Phone Number
1-800-637-7893
Web Address
www.proenzol.com
Pharmacist Counseling Corner

Sugar/Starch DigestEnz by ProEnzol: Common Questions

Does Sugar/Starch DigestEnz by ProEnzol interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Sugar/Starch DigestEnz. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Sugar/Starch DigestEnz contains 16 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this actually help with lactose intolerance?
Yes — lactase, one of the enzymes in this blend, is effective for lactose intolerance. It breaks down lactose (milk sugar) so your body can digest it. How much it helps depends on your dose and how severe your intolerance is.
What's the difference between all these enzyme names?
Each one breaks down a different food component. Protease handles protein, lipase handles fat, lactase handles milk sugar, and the others target different starches and fibers. Together they're meant to cover the range of foods you eat.
Can I take this if I'm pregnant?
The safety data is limited for most of these enzymes during pregnancy. Protease and lipase are best avoided unless your doctor advises it. For the others, there isn't enough data to say either way. Talk with your doctor or pharmacist about whether this product is right for you.
What side effects should I watch for?
Most people tolerate these enzymes well. Occasionally they may cause digestive upset. Allergic reactions are rare but have been reported, especially in people heavily exposed to powdered enzymes. If you notice any unusual symptoms, stop and contact your pharmacist.
Is this safe while breastfeeding?
There's little safety data on these enzymes during breastfeeding. Check with your doctor or pharmacist before using this product regularly, so they can give you personalized advice.
Does this help with inflammatory bowel disease or other digestive disorders?
The evidence isn't clear. Lipase is sometimes used for these conditions, but the data we hold shows insufficient reliable evidence to rate it. If you have a serious digestive condition, talk with your doctor before starting any supplement.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Sugar/Starch DigestEnz is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Sugar/Starch DigestEnz label
Sources

Sources & How We Checked

Sugar/Starch DigestEnz's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Lactase 1 reference
  1. Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed

See these in context on the Lactase monograph →

Phytase 7 references
  1. Lei XG, Weaver JD, Mullaney E, Ullah AH, Azain MJ. Phytase, a new life for an "old" enzyme. Annu Rev Anim Biosci. 2013;1:283-309. PubMed
  2. Smuts CM, Matsungo TM, Malan L, et al. Effect of small-quantity lipid-based nutrient supplements on growth, psychomotor development, iron status, and morbidity among 6- to 12-mo-old infants in South Africa: a randomized controlled trial. Am J Clin Nutr. 2 PubMed
  3. van Heemst RC, Sander I, Rooyackers J, et al. Hypersensitivity pneumonitis caused by occupational exposure to phytase. Eur Respir J. 2009;33(6):1507-9. PubMed
  4. Baur X, Melching-Kollmuss S, Koops F, Strassburger K, Zober A. IgE-mediated allergy to phytase -- a new animal feed additive. Allergy. 2002;57(10):943-5. PubMed
  5. Doekes G, Kamminga N, Helwegen L, Heederik D. Occupational IgE sensitisation to phytase, a phosphatase derived from Aspergillus niger. Occup Environ Med. 1999;56(7):454-9. PubMed
  6. Brnic M, Hurrell RF, Songré-Ouattara LT, et al. Effect of phytase on zinc absorption from a millet-based porridge fed to young Burkinabe children. Eur J Clin Nutr. 2017;71(1):137-141. PubMed
  7. Koshy JC, Sharabi SE, Feldman EM, Hollier LH Jr, Patrinely JR, Soparkar CN. Effect of dietary zinc and phytase supplementation on botulinum toxin treatments. J Drugs Dermatol. 2012;11(4):507-12.

See these in context on the Phytase monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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