System-Six By Irwin Naturals Overview & Drug Interactions

Vitamin E is a fat-soluble vitamin found naturally in a variety of foods, including vegetable oils, nuts, seeds, and leafy green vegetables. Vitamin E is also available as a dietary supplement and is often added to skincare products. Vitamin E has many roles in the body, including protecting cells from oxidative stress and supporting immune function.

Niacin, also known as vitamin B3, is a water-soluble vitamin found in a variety of foods, including meat, poultry, fish, and fortified grains. It plays a variety of roles in the body, including in the metabolism of carbohydrates, fats, and proteins. It is also necessary for the production of energy in the body and in the synthesis of different hormones. Niacin deficiency is rare in developed countries, however, supplementation has been shown to have several positive benefits. For example, it can reduce the risk of diabetic neuropathy (i.e., nerve pain) and has been shown effective for treating some types of high cholesterol (extended-release niacin is used as a prescription drug in the United States for this purpose). There is a multitude of niacin forms available as dietary supplements, including NADH, niacinamide, and nicotinamide riboside, all with different properties.

Vitamin B12, also known as cobalamin, is a water-soluble vitamin crucial for several bodily functions. It plays a pivotal role in the formation of red blood cells, aiding in the prevention of anemia. Vitamin B12 is essential for maintaining a healthy nervous system and proper brain function, as it is involved in the synthesis of myelin, the protective sheath around nerve fibers. This vitamin is primarily found in animal-based foods such as meat, fish, dairy products, and eggs, making it important for vegetarians and vegans to consider supplementation. A deficiency in vitamin B12 can lead to neurological issues, fatigue, and cognitive impairment.

Choline is an essential nutrient that is found in many foods, including eggs, and is important for a number of bodily functions, including liver function, brain development, and nerve function. Choline is a precursor to acetylcholine, a neurotransmitter that plays a role in memory, mood, and muscle control. Choline also helps to transport fats out of the liver, which may help to reduce the risk of liver disease. Choline supplements are available in different forms, including choline bitartrate, choline chloride, and phosphatidylcholine. Choline bitartrate is the most common form of choline supplement, but phosphatidylcholine is the form that is found naturally in foods.

Selenium is an essential trace element that plays a crucial role in various physiological functions in the human body. It is often included in dietary supplements due to its antioxidant properties and its contribution to maintaining a healthy immune system. Selenium is important for thyroid function and may also have a role in protecting against certain chronic diseases. However, it's essential to note that excessive selenium intake can be harmful, so it's crucial to adhere to recommended daily allowances and consult with a healthcare professional before taking selenium supplements.

Chromium is a trace mineral that is found in small amounts in the human body. It is believed to play a role in the metabolism of carbohydrates, fats, and proteins. It is used as a dietary supplement for its purported ability to help with weight loss and blood sugar control. There is some evidence to suggest that chromium supplements may help to improve blood sugar control in people with type 2 diabetes, although the results of studies on this topic have been mixed. Some studies have found that chromium supplements can improve insulin sensitivity and reduce blood sugar levels in those with poorly controlled diabetes, while others have found no significant effects.

Fish oil is a dietary supplement derived from fatty fish like mackerel, salmon, and anchovies. It's rich in omega-3 fatty acids, specifically eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). These fatty acids are crucial for various bodily functions, including brain health, heart health, and reducing inflammation. Fish oil is often consumed to support cardiovascular health, lower blood triglyceride levels, and potentially alleviate symptoms of certain inflammatory conditions. It is available in various forms, such as capsules, liquid, and as an ingredient in fortified foods.

Garcinia is a plant genus in the family Clusiaceae, and is native to Asia, Australia, tropical and southern Africa, and Polynesia. The most well-known species is Garcinia cambogia, which is native to Indonesia. Garcinia cambogia is rich in hydroxycitric acid (HCA), which is thought to be the main active component responsible for its purported medicinal effects of promoting weight loss and appetite suppression.

Green tea is a type of tea that is made from the leaves of the Camellia sinensis plant. It is native to Asia and is widely consumed throughout the world. Green tea has a mild, slightly grassy flavor and is typically lighter in color and less astringent than black tea. Green tea is a rich source of antioxidants, particularly a group of compounds called catechins. These antioxidants are thought to help protect cells from damage caused by free radicals. Green tea is also a good source of other nutrients, including vitamin C and several B vitamins. Green tea is often consumed for a number of purported health benefits including reducing the risk of heart disease, immune-stimulating effects, and weight loss. Oral green tea supplements, containing dried powder, are most often utilized for the caffeine content and used as an appetite suppressant for weight loss.

Schisandra is a plant that is native to parts of Asia, and is known for its small, red berries. These berries are often dried and sold as a dietary supplement to be used as a natural remedy for a wide range of health conditions, including fatigue, anxiety, and respiratory problems. Some people also use schisandra to improve sleep quality and reduce the symptoms of menopause. It is considered an 'adaptogen', which is believed to help the body adapt to stress.

Theanine, often referred to as L-theanine as that is the predominant isomer of theanine, is an amino acid commonly found in tea leaves, particularly in green tea. It is purported to increase levels of GABA, serotonin, and dopamine in the brain, which can help to reduce stress and anxiety. L-theanine may also promote a sense of calm and improve overall well-being. Some studies have also suggested that it may improve cognitive function, although more research is needed. Most reported drug interactions with theanine are due to its sedative effects.

L-tyrosine is a non-essential amino acid produced within the body through the conversion of the essential amino acid, phenylalanine. It is often used as a dietary supplement to support cognitive function, enhance focus, and mitigate stress by serving as a precursor for neurotransmitters like dopamine and norepinephrine.

Ginger is a spice native to Asia and part of the Zingiberaceae family. It has a pungent, spicy flavor and is often used to add flavor to dishes and drinks. Ginger has a long history of use in traditional medicine and is believed to have anti-inflammatory, antioxidant, and other medicinal properties. It is commonly used to treat nausea, motion sickness, and other digestive issues. Ginger is also sometimes used to relieve pain and reduce inflammation. Ginger supplements generally standardize several compounds found in the root, and are often labeled as containing a certain amount of 'ginger root extract'.

Guarana (Paullinia cupana) is a plant native to the Amazon rainforest in South America. The seeds of the guarana plant are used in traditional medicine and as a dietary supplement. Guarana is often marketed as a natural stimulant and is claimed to improve physical performance, increase energy and alertness, and reduce fatigue. It is sometimes added to energy drinks, weight loss supplements, and other products. Guarana seeds typically contain around 3-6% caffeine, although some extracts may contain far more. Guarana, when used in dietary supplements, is often standardized for its caffeine and tannin content.

Inositol is a type of carbohydrate (sugar alcohol) that is found in a variety of foods, including fruits, nuts, and grains. It is also known as vitamin B8 but is not considered 'essential' as it can be synthesized in the human body. Inositol is involved in a number of important physiological processes, including the metabolism of fats, the regulation of insulin, and the transmission of nerve impulses. Inositol is a popular dietary supplement and is believed to have a number of potential health benefits. It is thought to have a role in the treatment of certain mental health conditions, is believed to have a positive effect on cholesterol levels and may be helpful in the prevention or management of heart disease. In addition, inositol may have anti-inflammatory effects and may be helpful in the treatment of certain skin conditions.