Systemic Care By XtendLife Overview & Drug Interactions

Niacin, also known as vitamin B3, is a water-soluble vitamin found in a variety of foods, including meat, poultry, fish, and fortified grains. It plays a variety of roles in the body, including in the metabolism of carbohydrates, fats, and proteins. It is also necessary for the production of energy in the body and in the synthesis of different hormones. Niacin deficiency is rare in developed countries, however, supplementation has been shown to have several positive benefits. For example, it can reduce the risk of diabetic neuropathy (i.e., nerve pain) and has been shown effective for treating some types of high cholesterol (extended-release niacin is used as a prescription drug in the United States for this purpose). There is a multitude of niacin forms available as dietary supplements, including NADH, niacinamide, and nicotinamide riboside, all with different properties.

Biotin, also known as vitamin H or vitamin B7, is a water-soluble vitamin that plays a role in various metabolic processes in the body. It is necessary for the growth and maintenance of healthy skin, hair, and nails, and is also involved in the metabolism of carbohydrates, fats, and amino acids. Biotin is considered to be generally safe when consumed in the recommended daily amounts but it is important to note that consuming large amounts of biotin-containing supplements or products can cause falsely high or falsely low test results for certain laboratory tests, such as those for thyroid function, hormone levels, and certain biomarkers for certain diseases.

Calcium is a vital nutrient found in various foods such as dairy products, certain vegetables, and many fortified items. Over 99% of the body's calcium is stored in the bones and teeth, predominantly as hydroxyapatite. The remaining calcium circulates in the blood, extracellular fluid, muscles, and other tissues, where it is essential for processes like nerve signaling, muscle contraction, vascular activities, glandular secretion, and maintaining cell membrane and capillary permeability. It also plays critical roles in enzyme reactions, respiration, kidney function, and blood clotting, and is involved in neurotransmitter and hormone release, amino acid uptake, vitamin B12 absorption, and gastrin secretion. Calcium balance changes with age: it is positive during periods of growth, stable in adulthood, and tends to become negative in older age. Calcium loss occurs through feces, urine, sweat, and shedding skin cells. In women, reduced estrogen levels decrease calcium absorption and retention, increase bone turnover, and lead to lower bone mass. Calcium supplements come in various forms, including citrate and carbonate, which differ mainly in their calcium content and absorption rates. Calcium citrate is easily absorbed and can be taken without food, making it suitable for older adults or those with low stomach acid. In contrast, calcium carbonate, which contains a higher percentage of calcium, is best absorbed when taken with meals.

Magnesium is a mineral that is essential for the proper functioning of the body. It plays a role in many important physiological processes, including the contraction and relaxation of muscles, the transmission of nerve impulses, and the regulation of blood pressure. Magnesium is found in a variety of foods, including leafy green vegetables, nuts, and grains, and it is also available as a dietary supplement. There are several different forms of magnesium that are available as supplements, all of which can be used to prevent deficiency. Additionally, magnesium is purported to have several different health benefits, such as improving sleep, reducing muscle cramps, reducing anxiety, and preventing or treating migraines. Although magnesium is essential for health, magnesium-containing foods and supplements can interact with some prescription medications if used at the same time.

Zinc is a mineral that is essential for the proper functioning of the human body. It is involved in many important physiological processes, including immune system function, wound healing, taste, and smell. Zinc is found in a variety of foods, including meat, seafood, and whole grains, and it is also available as a dietary supplement. Zinc supplements may be used to treat or prevent zinc deficiency, which can occur due to certain medical conditions, such as gastrointestinal disorders, alcohol abuse, and certain medications. Zinc supplements may also be used for other purposes, such as to boost the immune system, improve acne, and reduce the severity and duration of colds. There are several different forms of zinc supplements available, including zinc gluconate, zinc acetate, and zinc sulfate. The most common form of zinc supplements is zinc gluconate, which is well absorbed and is less likely to cause stomach-related side effects than other forms of zinc.

Selenium is an essential trace element that plays a crucial role in various physiological functions in the human body. It is often included in dietary supplements due to its antioxidant properties and its contribution to maintaining a healthy immune system. Selenium is important for thyroid function and may also have a role in protecting against certain chronic diseases. However, it's essential to note that excessive selenium intake can be harmful, so it's crucial to adhere to recommended daily allowances and consult with a healthcare professional before taking selenium supplements.

Manganese is an essential trace mineral that plays a vital role in various physiological processes within the human body. It is required for proper brain function, bone formation, enzyme activation, and wound healing. Manganese also contributes to metabolism, antioxidant defense, and the formation of connective tissues.

Chromium is a trace mineral that is found in small amounts in the human body. It is believed to play a role in the metabolism of carbohydrates, fats, and proteins. It is used as a dietary supplement for its purported ability to help with weight loss and blood sugar control. There is some evidence to suggest that chromium supplements may help to improve blood sugar control in people with type 2 diabetes, although the results of studies on this topic have been mixed. Some studies have found that chromium supplements can improve insulin sensitivity and reduce blood sugar levels in those with poorly controlled diabetes, while others have found no significant effects.

Bitter melon, also known as bitter gourd or karela, is a tropical fruit native to Asia, Africa, and the Caribbean. It is a long, green fruit with a bumpy exterior and flesh that is pale green or white in color. In traditional medicine, bitter melon is purported to have a number of health benefits. It is a rich source of antioxidants and has been historically used as a natural remedy for a variety of ailments, including diabetes, asthma, and immune conditions.

Gymnema (Gymnema sylvestre) is a plant species native to India and Africa that has been used traditionally in Ayurvedic medicine for centuries to treat a range of conditions, including diabetes, obesity, and digestive problems. Gymnema is thought to work by inhibiting the absorption of sugar in the intestines and by increasing the production of insulin in the pancreas. If applied topically to the tongue, it reduces the sweetness and bitter sensation of foods, which may deter excess sugar intake (the plant is sometimes referred to informally as 'the sugar destroyer'). One of the most popular natural medicines utilized for dietary supplements, an extract of the leaf (Gymnema leaf extract) is the most often standardized for use, although the root can be used as well.

Green tea is a type of tea that is made from the leaves of the Camellia sinensis plant. It is native to Asia and is widely consumed throughout the world. Green tea has a mild, slightly grassy flavor and is typically lighter in color and less astringent than black tea. Green tea is a rich source of antioxidants, particularly a group of compounds called catechins. These antioxidants are thought to help protect cells from damage caused by free radicals. Green tea is also a good source of other nutrients, including vitamin C and several B vitamins. Green tea is often consumed for a number of purported health benefits including reducing the risk of heart disease, immune-stimulating effects, and weight loss. Oral green tea supplements, containing dried powder, are most often utilized for the caffeine content and used as an appetite suppressant for weight loss.

Milk thistle (Silybum marianum) is a plant belonging to the aster family (Asteraceae). It is native to the Mediterranean region and is widely cultivated in many parts of the world. The plant is known for its milk-white veins on the leaves, which gives it its name. Milk thistle has a long history of use in traditional medicine, and is extremely popular as a dietary supplement, making it one of the most well-known plants in the world. It is purported to have liver-protectant effects and has been used to treat liver disorders such as hepatitis and cirrhosis. It has also been used to treat gallbladder problems and high cholesterol. While there are a number of compounds in milk thistle, one of the active constituents, silymarin, is thought to be responsible for many of its effects, and dietary supplements often report using a standardized amount (generally 70% to 80% silymarin in extracts).

Quercetin is a type of flavonoid, which is a class of compounds found in a wide variety of plants and foods. It is purported to have a number of health benefits such as anti-inflammatory, antioxidant, and immune-boosting effects. Studies suggest it may also help to reduce the risk of certain chronic diseases, such as heart disease. In addition, quercetin may have anti-allergic properties and may be helpful in the treatment of allergies and asthma. It is a popular dietary supplement worldwide and is often included in products that contain antioxidants or various vitamins/minerals. Its wide range of potential health benefits mean that it could potentiate the effects of other drugs (e.g., anti-hypertensives), which is why there are an abundant number of potential interactions listed for quercetin.

Valerian (Valeriana officinalis) is a perennial herb native to Europe and Asia. The plant is known for its strong, distinctive odor and its purported medicinal effects. Valerian contains a number of active compounds, including valerenic acid and valepotriates, which are believed to have a sedative effect on the body and are may to be helpful in the treatment of insomnia and anxiety. Valerian is also believed to have mild tranquilizing and muscle-relaxing properties and may be helpful in the treatment of muscle spasms and other muscle disorders. The root of the valerian plant is most commonly utilized in dietary supplements and is often standardized for valerenic acid content.

Inositol is a type of carbohydrate (sugar alcohol) that is found in a variety of foods, including fruits, nuts, and grains. It is also known as vitamin B8 but is not considered 'essential' as it can be synthesized in the human body. Inositol is involved in a number of important physiological processes, including the metabolism of fats, the regulation of insulin, and the transmission of nerve impulses. Inositol is a popular dietary supplement and is believed to have a number of potential health benefits. It is thought to have a role in the treatment of certain mental health conditions, is believed to have a positive effect on cholesterol levels and may be helpful in the prevention or management of heart disease. In addition, inositol may have anti-inflammatory effects and may be helpful in the treatment of certain skin conditions.

Banaba (Lagerstroemia speciosa) is a plant species in the family Lythraceae. It is native to tropical regions of Asia, including the Philippines, India, and Malaysia. It is commonly used as a natural remedy to lower blood sugar levels in people with diabetes, and has also been used to treat high blood pressure, obesity, and kidney problems. Banaba contains a number of active compounds, including corosolic acid, ellagitannins, and lagerstroemin, which are believed to be responsible for its medicinal effects. Dietary supplements are generally made from the leaf of the plant. Patented extracts of banaba, such as Glucosol (i.e., Glucofit), are often utilized in dietary supplements as well.

Betaine hydrochloride (HCL) is a supplement that is sometimes used to increase the amount of hydrochloric acid in the stomach. Hydrochloric acid is an important component of stomach acid that helps to break down food and kill harmful bacteria. As a dietary supplement, it is used to help with digestion problems such as bloating, gas, and indigestion. It is also used to help people with conditions such as low stomach acid, heartburn, and acid reflux.

Bromelain is a group of proteolytic enzymes derived from pineapples. It has been traditionally used for its anti-inflammatory and protein-digesting properties. Some research suggests it may have potential benefits for conditions such as allergic rhinitis, burns, cancer, diabetic foot ulcers, and postoperative pain, among others. However, the evidence for its effectiveness in these areas is lacking, and more research is needed. It is important to note that bromelain should not be confused with other protein-digesting enzymes. Pregnant and lactating individuals should avoid using bromelain due to insufficient information about its safety in these populations.

Alpha-lipoic acid (ALA) is a naturally occurring compound that is made by the body and is also found in some foods, such as spinach, broccoli, and potatoes. It plays a role in energy production in the body and acts as an antioxidant, helping to protect cells from damage caused by free radicals. ALA has been studied for its potential health benefits, including the treatment of certain types of nerve damage, diabetes, and liver disease.

Black seed, also known as black cumin, is a flowering plant belonging to the Ranunculaceae family. It is used in traditional medicine for the treatment of several conditions, including bronchitis, colic, fatigue, fever, headache, toothache, back pain, and infections. Most dietary supplements containing black seed market it as supporting the respiratory and digestive system, as well as improving immune health. Black seed oil is obtained from the seeds being cold-pressed. In regard to supplements, whole black seeds contain both the oil and other components such as fiber and proteins, while black seed oil is a concentrated source of the oil only. Both can be taken as supplements, but black seed oil contains larger amounts of active components, while whole seeds can provide additional nutrients and fiber.