No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Tendo-Fix Ingredients & Drug Interactions

by SuperSmart

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Tendo-Fix is a dietary supplement by SuperSmart with 2 active ingredients. Its ingredients are commonly taken for joint pain and stiffness, osteoarthritis, joint flexibility and range of motion.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Tendo-Fix by SuperSmart

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 8 active ingredients.
  • “Eggshell Membrane” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.
  • “TendoGuard” is listed as a grouped ingredient — the label gives one combined amount (750 mg) without saying how much of each component you get.

Tendo-Fix is a joint-support capsule with eight active ingredients. Hyaluronic acid — a substance your body naturally makes and uses to cushion joints and keep skin hydrated — is the only one we have detailed safety and effectiveness information for.

The other actives are structural proteins and compounds: collagen types I, II, V, and X; chondroitin; mucopolysaccharides; eggshell membrane; and chicken. The capsule also contains two inactive ingredients: acacia gum and white rice flour.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Hyaluronic Acid's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Joint comfort and connective tissue support.
  • We looked for evidence on: Osteoarthritis, Exercise-induced muscle soreness, Joint flexibility, Joint pain and stiffness.
  • The closest evidence on file: Hyaluronic Acid is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced muscle soreness (Natural Medicines).
  • Also on file: Hyaluronic Acid is rated "Insufficient Reliable Evidence To Rate" for Osteoarthritis.

In our data, hyaluronic acid is rated possibly effective for dry eye and venous leg ulcers (slow-healing sores on the lower leg), though the evidence is modest. For aging skin, hay fever, and sexual dysfunction, we don't have enough reliable evidence to say whether it works.

The effectiveness of the other seven active ingredients in this product — the collagens, chondroitin, mucopolysaccharides, eggshell membrane, and chicken — is not documented in our database, so we can't comment on their impact.

The evidence, ingredient by ingredient Eggshell Membrane

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Hyaluronic acid is generally well tolerated by most adults when taken by mouth or applied to skin. That said, long-term safety of supplements isn't fully studied, and the safety data for oral supplements advises caution.

The product's safety notes emphasize that there isn't enough long-term safety information to recommend oral hyaluronic acid supplements unless a doctor advises it. We have no pregnancy or breastfeeding safety data on file for any of the active ingredients in this product.

If you're pregnant, breastfeeding, or planning either, talk with your doctor or pharmacist before starting.

Side effects, ingredient by ingredient Eggshell Membrane

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

We have no documented interactions between this product's ingredients and any medications. However, we could not check most of the active ingredients — mucopolysaccharides, chondroitin, and the various collagens — so interactions may exist.

Use the medication checker below with your exact prescriptions before you start.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

Tendo-Fix is a joint-support blend, and hyaluronic acid within it is possibly effective for dry eye and leg ulcers — though evidence is limited. Most of the product's ingredients haven't been checked for drug interactions.

Before you take it, run your medications through the tool on this page, and if you're pregnant, breastfeeding, or have questions about long-term use, check with your pharmacist or doctor.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 8 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Tendo-Fix, straight from the product label.

Brand SuperSmart
Barcode (UPC) 5453003827122
Net contents 90 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Jul 24, 2025
DSLD ID 332533
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Tendo-Fix by SuperSmart, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
30
UPC/BARCODE
5453003827122
IngredientAmount% DV
Mucopolysaccharides0 NP--
Protein0 NP--
Hyaluronic Acid0 NP--
Chondroitin0 NP--
Collagen Type II0 NP--
Eggshell Membrane0 NP--
Collagen Type I0 NP--
TendoGuard750 mg--
Chicken0 NP--
Collagen Type V0 NP--
Collagen Type X0 NP--

Other ingredients: Acacia Gum, White Rice Flour

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

TendoGuard, Certified Nutraceuticals, USA, US Patent #8,344,106 B1.

Each capsule contains 250 mg TendoGuard.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Adults. Take 3 capsules a day.

Precautions

Precautions: Contains egg extract.

Do not exceed the recommended daily dose. This product is a nutritional supplement and should not replace a varied, balanced diet.

Keep out of childrens' reach.

As with any nutritional supplement, you should consult a health professional before taking this product if you are pregnant, breastfeeding or have a health problem.

Storage

Store away from direct light, heat and humidity.

See for yourself

Tendo-Fix by SuperSmart label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Tendo-Fix by SuperSmart

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size3 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

TendoGuard

750 mg per serving

Other (inactive) ingredients: Acacia Gum, White Rice Flour. These complete the product’s ingredient list but are not active constituents.

Interaction report

Tendo-Fix by SuperSmart Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Tendo-Fix. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Tendo-Fix, from the product label.

SuperSmart

See all SuperSmart products
Name
SN Worldwide Unipessoal, Lda
Street Address
Avenida Do Infante 66, Edificio Quinta Avenida 1 C
City
Funchal
ZipCode
9000-015
Pharmacist Counseling Corner

Tendo-Fix by SuperSmart: Common Questions

Does Tendo-Fix by SuperSmart interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Tendo-Fix. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Tendo-Fix contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is hyaluronic acid, and what's it supposed to do?
Hyaluronic acid is a naturally occurring compound that holds water and cushions joints and skin. In this product, it's included for joint support, though in our data it's documented as possibly effective mainly for dry eye and certain leg ulcers rather than general joint health.
Is hyaluronic acid safe to take by mouth?
Orally, hyaluronic acid appears to be well tolerated. However, long-term safety of oral supplements isn't fully studied, and the safety data advises caution. If you want to use an oral hyaluronic acid supplement, it's best to talk with your doctor first.
What about the other ingredients — collagen, chondroitin, and the rest?
We don't have interaction or safety data on file for them. They're structural proteins and compounds found naturally in connective tissue, but we can't comment on their effectiveness or long-term safety from our database.
Can I take this if I'm pregnant or breastfeeding?
We don't have pregnancy or breastfeeding safety data for any of the active ingredients in this product. Talk with your doctor or pharmacist to decide whether it's right for you in those circumstances.
Does this product have fillers or other inactive ingredients I should know about?
Yes — it contains acacia gum and white rice flour as inactive ingredients. These are common binders and flow agents in supplements.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Tendo-Fix is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Tendo-Fix label
Sources

Sources & How We Checked

Tendo-Fix's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Hyaluronic Acid 4 references
  1. Park Y, Song JS, Choi CY, Yoon KC, Lee HK, Kim HS. A randomized multicenter study comparing 0.1%, 0.15%, and 0.3% sodium hyaluronate with 0.05% cyclosporine in the treatment of dry eye. J Ocul Pharmacol Ther. 2017;33(2):66-72. PubMed
  2. U.S. Food and Drug Administration. Do Not Use Needle-Free Devices for Injection of Dermal Fillers - FDA Safety Communication. October 8, 2021. Available at: https://www.fda.gov/medical-devices/safety-communications/do-not-use-needle-free-devices-injection
  3. Disphanurat W, Srisantithum B. Efficacy and safety of 0.15% isobutylamido thiazolyl resorcinol combined with hyaluronic acid vs 0.15% isobutylamido thiazolyl resorcinol or hyaluronic acid alone in melasma treatment: A randomized evaluator-blind trial. J C PubMed
  4. Humbert P, Mikosinki J, Benchikhi H, Allaert FA. Efficacy and safety of a gauze pad containing hyaluronic acid in treatment of leg ulcers of venous or mixed origin: a double-blind, randomised, controlled trial. Int Wound J 2013;10(2):159-66. PubMed

See these in context on the Hyaluronic Acid monograph →

Eggshell Membrane 3 references
  1. Osteoarthritis — MedlinePlus (NIH) Source
  2. Dietary Supplements: What You Need to Know — NIH Office of Dietary Supplements Source
  3. Using Dietary Supplements Wisely — NIH NCCIH Source

See these in context on the Eggshell Membrane monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring