Major interaction on record — check this product against your medications before combining. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

The Razor's Edge Ingredients & Drug Interactions

by Blackstone Labs

The Razor's Edge label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking The Razor's Edge against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

The Razor's Edge is a dietary supplement by Blackstone Labs with 3 active ingredients. Its ingredients are commonly taken for memory and thinking, brain health and aging, stroke recovery support.Based on those ingredients, 1,057 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Adrafinil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against The Razor's Edge by Blackstone Labs

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HelloPharmacist Scorecard of The Razor's Edge by Blackstone Labs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 3 active ingredients.
  • “THE RAZOR'S EDGE(TM) MATRIX” is a proprietary blend — the label doesn't break down how much of each component you get.

The Razor's Edge contains 3 active ingredients. CDP Choline (citicoline) supports brain health and has been studied for age-related memory loss and certain eye conditions.

Adrafinil is a stimulant precursor — your body converts it to a compound similar to the prescription drug modafinil — and it's designed to promote alertness and mental focus. Phenylpiracetam is a racetam-type nootropic that rounds out the formula.

The capsules also contain inactive ingredients: magnesium stearate, silicon dioxide, and titanium dioxide.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Enhanced focus, increased alertness, improved cognition.
  • We looked for evidence on: Mental alertness, Attention deficit-hyperactivity disorder (ADHD), Age-related cognitive decline, Alzheimer disease, Vascular dementia, Traumatic brain injury (TBI) — and 4 related terms.
  • The strongest evidence on file: Citicoline is rated "Possibly Effective" for Age-related cognitive decline (Natural Medicines).
  • Also on file: Citicoline is rated "Possibly Ineffective" for Stroke.
  • Also on file: Citicoline is rated "Insufficient Reliable Evidence To Rate" for Alzheimer disease, Attention deficit-hyperactivity disorder (ADHD), Cerebrovascular disease, Vascular dementia, and more.

CDP Choline is possibly effective for age-related cognitive decline and glaucoma, though the evidence for Alzheimer's disease, traumatic brain injury, and cardiac arrest is not yet established. Adrafinil's effectiveness for cognitive decline, mental alertness, athletic performance, and obesity has insufficient reliable evidence in our data — the science doesn't clearly support those claims yet.

We hold no effectiveness data for Phenylpiracetam.

The evidence, ingredient by ingredient Citicoline Adrafinil

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

CDP Choline is generally well tolerated in studies, but long-term safety isn't fully established. Common side effects may include abdominal pain, back pain, headache, insomnia, nausea, diarrhea, and blurred vision.

Adrafinil converts to a stimulant-like drug and may stress the liver, so casual use isn't advised. Reported side effects include disturbed sleep, headache, malodorous urine, and unpleasant stimulation; rarely, orofacial dyskinesia has been reported.

Some people report withdrawal-like symptoms — fatigue, irritability, headache — after stopping it. During pregnancy, CDP Choline and adrafinil safety data is insufficient or absent — both should be avoided.

The same applies to breastfeeding: there isn't enough data to know either way, so talk with your doctor or pharmacist for personalized guidance.

Side effects, ingredient by ingredient Citicoline Adrafinil

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Adrafinil.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 1,058 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking The Razor's Edge, double-check if you're on modafinil (Provigil) — the combination carries serious risk. Also review any blood pressure medications, other stimulant drugs, and prescriptions processed through your liver enzymes (CYP2C19, CYP2C9, CYP3A4, CYP1A2 substrates, or CYP3A4 inhibitors).

Use the checker on this page to search your exact medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This is a multi-ingredient nootropic designed for focus and cognitive support. If you take any prescription medications — especially blood pressure drugs, stimulants, or drugs metabolized by your liver — you'll need to check them against the interaction list below before starting.

Avoid during pregnancy and breastfeeding. Chat with your pharmacist or doctor about whether it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about The Razor's Edge, straight from the product label.

Brand Blackstone Labs
Barcode (UPC) 616641803476
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Jul 24, 2015
DSLD ID 47216
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for The Razor's Edge by Blackstone Labs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
60
UPC/BARCODE
616641803476
IngredientAmount% DV
CDP Choline0 NP--
Adrafinil0 NP--
Phenylpiracetam0 NP--
THE RAZOR'S EDGE(TM) MATRIX0 NP--

Other ingredients: Magnesium Stearate, Silicon Dioxide, Titanium Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

BLACKSTONE LABS THE RAZOR'S EDGE (TM)

Suggested/Recommended/Usage/Directions

Directions of usage: As a dietary supplement, take one (1) to two (2) capsules per day in the morning, or 30 minutes before you need to be focused.

General Statements

Visit our website for additional information and guidance.

Enhanced focus Increased alertness Improved cognitive ability

Consult your health care professional before using any dietary supplement.

Brain stimulating Nootropic formula

Razor sharp mentality

Precautions

WARNING: Do not exceed the recommended dose.

This product should not be used by anyone under the age of 21.

Do not use if pregnant or nursing, or if you are at risk of or being treated for diabetes or high blood pressure.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to cure or prevent, any disease.

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

The Razor's Edge by Blackstone Labs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

The Razor's Edge label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in The Razor's Edge by Blackstone Labs

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

THE RAZOR'S EDGE(TM) MATRIX

0 NP per serving

Other (inactive) ingredients: Magnesium Stearate, Silicon Dioxide, Titanium Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

The Razor's Edge by Blackstone Labs Drug Interactions

Want to check YOUR meds against The Razor's Edge?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,057Drugs
1 Major 1,056 Moderate

Ingredients driving the most interactions

Adrafinil 1,057

Individual Drug Interactions

The ingredients in The Razor's Edge interact with 1,057 drugs. Click any drug to see the details.

1 of the 3 ingredients in The Razor's Edge interact with drugs. Each result below shows which ingredient is responsible. Adrafinil

Each ingredient & the kinds of drugs it affects

For each ingredient in The Razor's Edge with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Adrafinil11 drug types · 1,057 drugs

Modafinil (Provigil)

Concomitant use might increase the risk for serious adverse effects.
Adrafinil is a precursor to the stimulant prescription drug modafinil. Concomitant use with modafinil would be expected to result in increased clinical and adverse effects.

Likelihood Likely Evidence D
Antihypertensive Drugs

Theoretically, adrafinil might reduce the effects of antihypertensive drugs.
Adrafinil is a precursor to the stimulant prescription drug modafinil. Modafinil has been shown to increase diastolic and systolic blood pressure. Retrospective analyses show that patients taking modafinil had a small but increased rate of requiring new antihypertensive drugs or increased use of antihypertensive drugs when compared with placebo.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, adrafinil might reduce the levels and clinical effects of CYP1A2 substrates.
Adrafinil is a precursor to the stimulant prescription drug modafinil. Modafinil has been shown to weakly induce CYP1A2 activity in vitro.

Likelihood Possible Evidence D
Cytochrome P450 2B6 (Cyp2B6) Substrates

Theoretically, adrafinil might reduce the levels and clinical effects of CYP2B6 substrates.
Adrafinil is a precursor to the stimulant prescription drug modafinil. Modafinil has been shown to weakly induce CYP2B6 activity in vitro.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, adrafinil might increase the levels and clinical effects of CYP2C19 substrates.
Adrafinil is a precursor to the stimulant prescription drug modafinil. Modafinil has been shown to inhibit CYP2C19 activity in vitro.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, adrafinil might increase the levels and clinical effects of CYP2C9 substrates.
Adrafinil is a precursor to the stimulant prescription drug modafinil. Modafinil has been shown to reduce CYP2C9 expression in vitro.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Inhibitors

Theoretically, drugs that inhibit CYP3A4 might increase the levels and clinical effects of adrafinil.
Adrafinil is a precursor to the stimulant prescription drug modafinil. Modafinil is metabolized by CYP3A4.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, adrafanil might reduce levels and clinical effects of CYP3A4 substrates.
Adrafinil is a precursor to the stimulant prescription drug modafinil. Modafinil has been shown to weakly induce CYP3A4 activity.

Likelihood Possible Evidence D
Monoamine Oxidase Inhibitors (Maois)

Theoretically, concomitant use might increase the risk for serious adverse effects.
Adrafinil is a precursor to the stimulant prescription drug modafinil. Modafinil, and a related drug, armodafinil, have been associated with reports of serious adverse effects, such as hypertensive crisis and hyperthermia, when used in combination with MAOIs.

Likelihood Possible Evidence D
Stimulant Drugs

Theoretically, taking adrafinil with stimulant drugs might have additive stimulant effects.
Adrafinil is a precursor to the prescription drug modafinil, which has stimulant effects.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, adrafinil might alter the effects and adverse effects of warfarin.
Adrafinil is a precursor to the stimulant prescription drug modafinil. Although pharmacokinetic research shows that modafinil does not alter levels of warfarin, this study was limited to a single dose. Experts recommend monitoring international normalized ratio (INR) in patients who are taking warfarin and initiating treatment with modafinil.

Likelihood Possible Evidence D
Adrafinil full monograph & interactions
The maker

Brand information

Manufacturer and brand details for The Razor's Edge, from the product label.

Blackstone Labs

See all Blackstone Labs products
Name
Blackstone Labs
City
Boca Raton
State
FL
ZipCode
33433
Phone Number
1-844-816-7803
Web Address
www.BlackStoneLabs.com
Pharmacist Counseling Corner

The Razor's Edge by Blackstone Labs: Common Questions

Does The Razor's Edge by Blackstone Labs interact with any medications?
Yes. Based on its ingredients, The Razor's Edge has a known interaction with 1,057 medications, including 1 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
The Razor's Edge contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is adrafinil and why is it in this product?
Adrafinil is a stimulant precursor — your body converts it into a compound similar to the prescription drug modafinil. It's included in The Razor's Edge to promote mental alertness and focus.
Can I take The Razor's Edge if I'm pregnant or breastfeeding?
No. CDP Choline should be avoided in pregnancy, and adrafinil has no safety data in pregnancy or breastfeeding — both should be avoided. Talk with your doctor or pharmacist about what's safe for you.
What are the most common side effects?
From CDP Choline: abdominal pain, back pain, headache, insomnia, nausea, and diarrhea. From adrafinil: disturbed sleep, headache, and unpleasant stimulation. Most people tolerate it, but side effects vary.
Is adrafinil regulated like a prescription drug?
Adrafinil isn't a prescription drug itself, but it converts in your body to a stimulant-like compound, and it may stress your liver — so it shouldn't be used casually without talking to your pharmacist first.
What does CDP Choline actually do?
CDP Choline (citicoline) supports brain function and has been studied for age-related memory loss and glaucoma. It appears possibly effective for those two conditions, though evidence for other brain conditions isn't established yet.
Can I stop taking The Razor's Edge anytime?
Anecdotally, some people report withdrawal-like symptoms — fatigue, irritability, headache — after stopping adrafinil. If you've been taking it regularly, talk with your pharmacist about how to stop safely.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

The Razor's Edge label
Go deeper

The Full Monographs Behind The Razor's Edge’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Citicoline

Citicoline is a naturally occurring compound involved in making brain cell membranes and the messenger chemical acetylcholine. It is popularly taken for memory, focus, and brain aging, and s...

Read the full Citicoline monograph → Herb & supplement monograph

Adrafinil

Interacts with 1,057 drugs

Adrafinil is a synthetic compound that the body converts into modafinil, a prescription wakefulness-promoting drug. It is sometimes sold as a nootropic supplement, but it is unregulated, car...

Read the full Adrafinil monograph →
Sources

Sources & How We Checked

The Razor's Edge's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 18 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Citicoline 11 references
  1. Spiers PA, Myers D, Hochanadel GS, et al. Citicoline improves verbal memory in aging. Arch Neurol 1996;53:441-8. PubMed
  2. Fioravanti M, Yanagi M. Cytidinediphosphocholine (CDP-choline) for cognitive and behavioural disturbances associated with chronic cerebral disorders in the elderly. Cochrane Database Syst Rev 2005;(2):CD000269. PubMed
  3. Conant R, Schauss AG. Therapeutic applications of citicoline for stroke and cognitive function in the elderly: A review of the literature. Altern Med Rev 2004;9:17-31.
  4. Warach, S., Pettigrew, L. C., Dashe, J. F., Pullicino, P., Lefkowitz, D. M., Sabounjian, L., Harnett, K., Schwiderski, U., and Gammans, R. Effect of citicoline on ischemic lesions as measured by diffusion-weighted magnetic resonance imaging. Citicoline 0 DOI
  5. Lukas, S. E., Kouri, E. M., Rhee, C., Madrid, A., and Renshaw, P. F. Effects of short-term citicoline treatment on acute cocaine intoxication and cardiovascular effects. Psychopharmacology.(Berl.) 2001;157(2):163-167. PubMed
  6. Dinsdale, J. R., Griffiths, G. K., Castello, J., Maddock, J., Ortiz, J. A., and Aylward, M. CDP-choline: repeated oral dose tolerance studies in adult healthy volunteers. Arzneimittelforschung. 1983;33(7A):1061-1065.
  7. Clark BC, Georgekutty J, Berul CI. Myocardial ischemia secondary to synthetic cannabinoid (K2) use in pediatric patients. J Pediatr 2015;167(3):757-61.e1. PubMed
  8. Ghajar A, Gholamian F, Tabatabei-Motlagh M, et al. Citicoline (CDP-choline) add-on therapy to risperidone for treatment of negative symptoms in patients with stable schizophrenia: a double-blind, randomized placebo-controlled trial. Hum Psychopharmacol. 2
  9. Castagna A, Manzo C, Fabbo A, Lacava R, Ruberto C, Ruotolo G. The CITIMERIVA Study: CITIcoline plus MEmantina plus RIVAstigmine in Older Patients Affected with Alzheimer's Disease. Clin Drug Investig. 2021 Feb;41(2):177-182. PubMed
  10. Jeong H, Yoon S, Sung YH, et al. Effects of cytidine-5'-diphosphate choline on gray matter volumes in methamphetamine-dependent patients: A randomized, double-blind, placebo-controlled study. J Psychiatr Res 2021;143:215-221. PubMed
  11. Nakazaki E, Mah E, Sanoshy K, Citrolo D, Watanabe F. Citicoline and Memory Function in Healthy Older Adults: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. J Nutr 2021;151(8):2153-2160. PubMed

See these in context on the Citicoline monograph →

Adrafinil 7 references
  1. Urban AE, Cubala WJ. The role of eugeroics in the treatment of affective disorders. Psychiatr Pol. 2020;54(1):21-33. PubMed
  2. Lowe DW, Dobson E, Jewett AG, Whisler EE. Adrafinil: Psychostimulant and purported nootropic? Am J Psych Res J. 2021;17(1):7-9. DOI
  3. Thobois S, Xie J, Mollion H, Benatru I, Broussolle E. Adrafinil-induced orofacial dyskinesia. Mov Disord 2004;19(8):965-6. PubMed
  4. Chariot J, Appia F, Vaille C, Rozé C. Effect of modafinil on pancreatic exocrine secretion in rats. A comparison with adrafinil and related drugs. Fundam Clin Pharmacol 1987;1(4):243-52. PubMed
  5. Kumar R. Approved and investigational uses of modafinil: an evidence-based review. Drugs. 2008;68(13):1803-39. PubMed
  6. Provigil (modafinil) [package insert]. North Wales, PA: Teva Pharmaceuticals USA, Inc. Published: January 2015. Accessed on: Nov 11, 2022.
  7. Kinslow, CJ, Shapiro SD, Grunebaum MF, Miller EC. Acute hypertensive crisis and severe headache after concurrent use of armodafinil and tranylcypromine: Case report and review of the literature. Clinical Short Communication. October 2018; 393:1-3. PubMed

See these in context on the Adrafinil monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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