Total Digestion Chewables Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Total Digestion Chewables against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Total Digestion Chewables is a dietary supplement by Loomis Enzymes with 9 active ingredients. Its ingredients are commonly taken for digestion and bloating, muscle soreness and exercise recovery, inflammation and swelling.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Total Digestion Chewables by Loomis Enzymes
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Total Digestion Chewables contains 9 active enzymes designed to support different stages of digestion. Protease breaks down proteins, Lipase tackles fats, and Lactase helps break down lactose in dairy — which is especially useful if you have trouble digesting milk products.
The blend also includes Amylase, Cellulase, Invertase, Glucoamylase, Hemicellulase, and Diastase, each working on different carbohydrates and fibers. These come in a chewable tablet with inactive ingredients like fructose, dextrose, and stevia leaf extract for sweetness and texture.
Does it work?
Strong evidence
Lactase in this product is effective for lactose intolerance — the enzyme helps your body digest milk sugar. For the other enzymes (Protease, Lipase, and the rest), the evidence we hold shows insufficient reliable evidence to rate them for common digestive complaints like dyspepsia (indigestion) or inflammatory bowel disease.
That means we don't have strong clinical proof they work for those uses, though many people take digestive enzyme supplements regularly.
How safe is it?
Well-documented data
Protease and Lipase are generally well tolerated in most adults, though digestive upset or allergic reactions are possible with protease in rare cases. Lactase is generally well tolerated when used as directed.
Rarely, workers exposed to powdered lactase have developed allergic reactions like contact dermatitis or allergic rhinitis — this is an occupational concern, not typical for people taking the supplement by mouth. For pregnancy: Lactase is likely safe, but safety data for Protease and Lipase during pregnancy is limited, so check with your doctor first.
During breastfeeding, there is little safety data for any of these enzymes, so ask your healthcare provider before using regularly. We have no pregnancy or breastfeeding data on file for the other ingredients.
Meds to double-check
No known interactions
No interactions are documented in our data for the enzymes we checked in this product. That said, always confirm with your pharmacist — especially if you take any digestive or stomach medications — since we couldn't verify six of the nine active ingredients.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
This product may help if you have lactose intolerance or want general digestive enzyme support. If you're pregnant, breastfeeding, or have a serious digestive condition, talk with your doctor before starting.
Run your medications through our checker and give your pharmacist a heads-up before you begin.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 9 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Total Digestion Chewables, straight from the product label.
| Brand | Loomis Enzymes |
|---|---|
| Barcode (UPC) | 697706060201 |
| Net contents | 90 Tablet(s) |
| Market status | On market |
| Date entered into DSLD | Feb 23, 2025 |
| DSLD ID | 327451 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Children 4 or More Years of Age |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Total Digestion Chewables by Loomis Enzymes, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Total Carbohydrates | 1 Gram(s) | 1% |
| Amylase | 0 NP | -- |
| Protease | 0 NP | -- |
| Lipase | 0 NP | -- |
| Lactase | 0 NP | -- |
| Cellulase | 0 NP | -- |
| Invertase | 0 NP | -- |
| Glucoamylase | 0 NP | -- |
| Hemicellulase | 0 NP | -- |
| Diastase | 0 NP | -- |
| Proprietary Enzyme Blend | 107 mg | -- |
Other ingredients: Fructose, Dextrose, Microcrystalline Cellulose, Mixed Berry Flavor, Natural, Citric Acid, Magnesium Stearate, Phytase, Silica, Stevia Leaf Extract
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
pHBS pH balancing system
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Precautions
Keep out of reach of children.
Note: Consult your physician before using this product if you are pregnant, nursing, taking medication, or have a medical condition.
Do not use if inner or outer seal is broken, torn, or missing.
Do not keep in the mouth because doing so can cause irritation to the gums and cheeks. Swallow water to rinse if irritation occurs.
Storage
To ensure freshness and potency, keep bottle tightly closed and store in a cool, dry place.
FDA Statement of Identity
A Dietary Supplement
Suggested/Recommended/Usage/Directions
Directions for use: Children over four years chew one tablet thoroughly before meals.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Total Digestion Chewables by Loomis Enzymes label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Total Digestion Chewables by Loomis Enzymes
These are the 9 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container90 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Other (inactive) ingredients: Fructose, Dextrose, Microcrystalline Cellulose, Mixed Berry Flavor, Natural, Citric Acid, Magnesium Stearate, Phytase, Silica, Stevia Leaf Extract. These complete the product’s ingredient list but are not active constituents.
Total Digestion Chewables by Loomis Enzymes Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Total Digestion Chewables. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Total Digestion Chewables, from the product label.
Loomis Enzymes
See all Loomis Enzymes products- Name
- Loomis Enzymes, LLC
- City
- Fitchburg
- State
- Wisconsin
- ZipCode
- 53719
- Phone Number
- 1-800-614-4400
- Web Address
- www.loomisenzymes.com
Total Digestion Chewables by Loomis Enzymes: Common Questions
Does Total Digestion Chewables by Loomis Enzymes interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is this safe during pregnancy?
What is Lactase in this product for?
Is Protease safe to take regularly?
Does this product have evidence it works?
Can I take this while breastfeeding?
What if I'm allergic to enzymes?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Total Digestion Chewables is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Total Digestion Chewables’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Proteolytic Enzymes (proteases)
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), trypsin, chymotrypsin, and pancreatin. Peo...
Read the full Proteolytic Enzymes (proteases) monograph → Herb & supplement monographLipase
Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy for people who cannot make enough of their...
Read the full Lipase monograph → Herb & supplement monographLactase
Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can reduce gas, bloating, cramping, and diarrhe...
Read the full Lactase monograph →Sources & How We Checked
Total Digestion Chewables's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 5 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Proteolytic Enzymes (proteases) 3 references
- Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
- Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
- Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed
See these in context on the Proteolytic Enzymes (proteases) monograph →
Lipase 1 reference
- Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed
Lactase 1 reference
- Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC