UC-II Ingredients & Drug Interactions
by NOW
What is this page for?
First and foremost: checking UC-II against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
UC-II is a dietary supplement by NOW with 3 active ingredients.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of UC-II by NOW
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
None of the active ingredients could be matched to our evidence database, so intended use can't be graded.
Why this rating?
- None of the active ingredients could be matched to a HelloPharmacist monograph, so intended use can't be graded against our evidence data.
Every active ingredient lists its own amount on the label.
Why this rating?
- The label discloses an exact amount for 3 of its 3 active ingredients.
- “UC-II Standardized Chicken Cartilage” is listed as a grouped ingredient — the label gives one combined amount (40 mg) without saying how much of each component you get.
None of the active ingredients could be matched to our interaction database.
Why this rating?
- We couldn't match any ingredient to a HelloPharmacist monograph, so there was nothing to check interactions against.
None of the active ingredients could be matched to our safety data.
Why this rating?
- We couldn't match any ingredient to a HelloPharmacist monograph, so there was no safety data to measure.
HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Medication interactions could not be assessed, and safety information could not be assessed.
Assessment coverage: 0 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 23, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about UC-II, straight from the product label.
| Brand | NOW |
|---|---|
| Barcode (UPC) | 733739031341 |
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | May 23, 2024 |
| DSLD ID | 314159 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for UC-II by NOW, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| UC-II Standardized Chicken Cartilage | 40 mg | -- |
| Total Collagen | 10 mg | -- |
| Aquamin | 250 mg | -- |
| Aquamin | 80 mg | 6% |
Other ingredients: Hypromellose, Microcrystalline Cellulose, Corn Starch, Potassium Chloride, Stearic Acid, Silicon Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested Usage: Take 1 capsule daily at bedtime on an empty stomach.
Formula
Cartilage is one of the primary connective tissues of the body, providing flexibility and support to joints. Undenatured Type II Collagen is the principal structural protein in cartilage that is responsible for its tensile strength and toughness. Derived from chicken sternum cartilage, the UC-II ingredient is a unique form of collagen with undenatured (native) type II collagen that works with the immune system to support healthy joints. Human clinical studies have found that supplementing with just one 40 mg capsule of UC-II per day can help to promote joint comfort, as well as healthy joint function and flexibility.
UC-II with undenatured type II collagen
Aquamin UC-II
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Formulation
Not manufactured with yeast, wheat, gluten, soy, milk, egg, fish, shellfish, tree nut or sesame ingredients.
Joint health
Promotes healthy joint comfort & function
Non-GMO
Natural color variation may occur in this product.
Made and quality tested in the USA with globally sourced ingredients.
Precautions
Not manufactured with yeast, wheat, gluten, soy, milk, egg, fish, shellfish, tree nut or sesame ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.
Caution: For adults only. Keep out of reach of children.
Consult physician if pregnant/nursing, taking medication, or have a medical condition.
General Statements
This bottle is made from 100% PCR (post-consumer recycled) resin.
General Health Family owned since 1968.
Seals/Symbols
GMP Quality Assured
FDA Statement of Identity
A Dietary Supplement
Brand IP Statement(s)
UC-II is a Lonza trademark, registered in the EU and/or USA. Aquamin is a registered trademark of Marigot Limited.
Storage
Store in a cool, dry place after opening.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
UC-II by NOW label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in UC-II by NOW
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
UC-II Standardized Chicken Cartilage
- › Total Collagen
Aquamin
Aquamin
Other (inactive) ingredients: Hypromellose, Microcrystalline Cellulose, Corn Starch, Potassium Chloride, Stearic Acid, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.
UC-II by NOW Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in UC-II. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for UC-II, from the product label.
NOW
See all NOW products- Name
- NOW FOODS
- Street Address
- 395 S. Glen Ellyn Rd.
- City
- Bloomingdale
- State
- IL
- ZipCode
- 60108
- Web Address
- nowfoods.com
UC-II by NOW: Common Questions
Does UC-II by NOW interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if UC-II is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
Sources & How We Checked
UC-II's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC