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Dietary supplement

Ultimate Eye Formula Ingredients & Drug Interactions

by Woodstock Vitamins

Capsule Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Ultimate Eye Formula is a dietary supplement by Woodstock Vitamins with 3 active ingredients. Its ingredients are commonly taken for eye health, age-related macular degeneration, cataract prevention.Based on those ingredients, 277 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bilberry concentrate, Blueberry concentrate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Ultimate Eye Formula by Woodstock Vitamins

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 3 active ingredients.
  • “BIL-MAX/BLU-MAX 2:1 Blend” is a proprietary blend — the label gives one combined amount (500 mg) without saying how much of each component you get.

Ultimate Eye Formula has three active ingredients working on eye and vision support. Blueberry concentrate and bilberry concentrate are both fruit extracts rich in anthocyanins, compounds that give berries their deep color and are thought to support eye tissue.

Lutein is a naturally occurring carotenoid — a pigment your eyes actually store in the retina — that's been studied for age-related eye conditions. The product also contains standard inactive ingredients: a capsule shell and magnesium stearate (a binding agent).

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: supports eye health.
  • We looked for evidence on: Age-related macular degeneration (AMD), Asthenopia (eye strain), Cataracts, Central serous retinopathy, Diabetic retinopathy, Dry eye — and 4 related terms.
  • The strongest evidence on file: Lutein is rated "Possibly Effective" for Age-related macular degeneration (AMD) (Natural Medicines).
  • Also on file: Lutein is rated "Possibly Effective" for Cataracts.
  • Also on file: Bilberry is rated "Insufficient Reliable Evidence To Rate" for Age-related macular degeneration (AMD), Cataracts, Diabetic retinopathy, Dry eye, and more.

The evidence for this formula is mixed. Lutein has possibly effective evidence for age-related macular degeneration (AMD) and cataracts, the two most common age-related eye problems.

Blueberry, on the other hand, does not have reliable evidence for any of the eye-related conditions listed — there's insufficient evidence for cognitive decline, anxiety, athletic performance, and cholesterol support, and it's rated possibly ineffective for high blood pressure. Bilberry is similar: night vision is rated possibly ineffective, and the evidence is insufficient for AMD, cognitive decline, and several other conditions.

If you're specifically concerned about cataracts or AMD, lutein is the ingredient here with documented support.

The evidence, ingredient by ingredient Lutein Blueberry Bilberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Blueberry concentrate is generally well tolerated, though freeze-dried blueberries can cause gastrointestinal side effects — constipation, diarrhea, nausea, and vomiting. In one clinical trial, about a quarter of participants taking 50 grams daily dropped out in the first week due to stomach complaints.

Lutein is well tolerated at doses up to 20 mg daily with no reported adverse effects. Bilberry is also generally well tolerated but may cause dark-colored stools, flatulence, and mild gastrointestinal discomfort in some people.

All three ingredients are rated likely safe in pregnancy and lactation, though the safety of concentrated blueberry and bilberry supplements — rather than food amounts — hasn't been extensively studied during these periods, so discuss with your doctor if you're pregnant or nursing.

Side effects, ingredient by ingredient Lutein Blueberry Bilberry

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 3 matched ingredients can interact with medications — Bilberry, Blueberry.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 277 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take Ultimate Eye Formula, check if you're on any blood thinners or antiplatelet drugs (warfarin, aspirin, clopidogrel) — bilberry carries a moderate interaction that could raise bleeding risk. Also double-check antidiabetes medications (insulin, metformin, sulfonylureas), as both berry extracts may lower blood sugar further.

If you take erlotinib for cancer, buspirone for anxiety, or flurbiprofen for pain, check those too — they all have documented interactions with these ingredients. Since the interaction list is long, the medication checker on this page is your best bet.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This formula combines two berry extracts and lutein for eye support. Lutein has decent evidence for cataracts and AMD.

If you take blood thinners, diabetes medications, or any other regular prescriptions, check them against our drug interaction tool before starting — the berry extracts in this product interact with over 270 medications. Talk to your pharmacist if you're on any of those drugs or have a sensitive stomach.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 11, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Ultimate Eye Formula, straight from the product label.

Brand Woodstock Vitamins
Barcode (UPC) 719985995316
Net contents 60 Vegan Capsule(s)
Market status On market
Date entered into DSLD Apr 11, 2022
DSLD ID 263214
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Ultimate Eye Formula by Woodstock Vitamins, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
719985995316
IngredientAmount% DV
Blueberry concentrate0 NP--
Lutein10 mg--
Bilberry concentrate0 NP--
BIL-MAX/BLU-MAX 2:1 Blend500 mg--

Other ingredients: Capsule, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Our powerful Ultimate Eye Formula supports eye health with a proprietary low heat process. Our Bio-Shield Technology concentrates, protects, and controls the release of nutrients that are easily damaged during processing or in the stomach.

SGS verified the process for manufacturing this product wit no GMO ingredients. www.sgs.com/no-gmo

We guarantee our supplements for potency and purity

Bio-Shield Technology

No GMO ingredients

GF Gluten free

Contains no: artificial colors, flavors, or preservatives; no wheat, gluten, milk, eggs, peanuts, tree nuts, soy, crustacean shellfish, or fish.

Formula

Lutein and zeaxanthin are carotenoids that promote eye health. Bilberries, native to northern Europe, are combined with blueberry concentrates in this full spectrum formula. Both are rich in anthocyanin compounds and other nutrients to support healthy eyes.

Lutemax 2020 lutein with bilberry & blueberry concentrates

Brand IP Statement(s)

BIL-MAX and BLU-MAX are registered trademarks of Cape Cod Biolab Corp. Lutemax 2020 trademark belongs to OmniActive Health Technologies Ltd.

Storage

Store in a cool, dry place.

Precautions

To report a serious adverse event, call 1-888-710-0006

Keep out of reach of children.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: Take one capsule up to two times daily with food.

See for yourself

Ultimate Eye Formula by Woodstock Vitamins label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Ultimate Eye Formula by Woodstock Vitamins

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Lutein

No known
interactions
10 mg per serving Form: Aztec Marigold flower extract, Lutemax 2020

Lutein is a plant-based antioxidant pigment that concentrates in the eye, and the best evidence suggests it (often combined with zeaxanthin) may help...

Lutein monograph & interactions

BIL-MAX/BLU-MAX 2:1 Blend

500 mg per serving

Other (inactive) ingredients: Capsule, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Ultimate Eye Formula by Woodstock Vitamins Drug Interactions

Want to check YOUR meds against Ultimate Eye Formula?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
277Drugs
275 Moderate 2 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Ultimate Eye Formula with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Bilberry concentrate4 drug types · 275 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, bilberry fruit extract might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro, animal, and clinical research suggest that anthocyanidin extracts from bilberry can inhibit platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, bilberry leaf or fruit extract may increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research suggests that bilberry leaf extract might have blood glucose-lowering activity. Also, one small clinical trial in patients with type 2 diabetes shows that taking bilberry fruit extract 470 mg as a single dose prior to an oral glucose tolerance test lowers plasma glucose levels when compared with placebo.

Likelihood Possible Evidence D
Cytochrome P450 2E1 (Cyp2E1) Substrates

Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Animal research shows that exposure to small concentrations of bilberry extract in drinking water for around one month increased CYP2E1 activity by 31%. However, exposure over a 2-month period did not increase CYP2E1 activity. This effect has not been reported in humans.

Likelihood Possible Evidence D
Erlotinib (Tarceva)

Theoretically, bilberry fruit extract might reduce the efficacy of erlotinib.
In vitro research suggests that bilberry fruit extract and its constituents, delphinidin and delphinidin-3-O-glucoside, inhibit the activity of erlotinib. This interaction has not been reported in humans.

Likelihood Possible Evidence D

Blueberry concentrate3 drug types · 88 drugs

Antidiabetes Drugs

Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal and in vitro research suggests that blueberry and/or blueberry leaf extracts can lower blood glucose levels.

Likelihood Unlikely Evidence D
Buspirone (Buspar)

Theoretically, blueberry juice might increase blood levels of buspirone.
In vitro research shows that blueberry juice can inhibit the metabolism of buspirone, possibly by inhibiting cytochrome P450 3A (CYP3A) enzymes. However, pharmacokinetic research in humans shows that drinking 300 mL of blueberry juice 30 minutes before taking buspirone hydrochloride 10 mg does not significantly affect the concentration or clearance of buspirone.

Likelihood Unlikely Evidence B
Flurbiprofen (Ansaid, Others)

Theoretically, blueberry juice might increase blood levels of flurbiprofen.
In vitro research shows that blueberry juice can inhibit the metabolism of flurbiprofen, possibly by inhibiting cytochrome P450 2C9 (CYP2C9) enzymes. However, pharmacokinetic research in humans shows that drinking 300 mL of blueberry juice 30 minutes before taking flurbiprofen 100 mg does not significantly affect the concentration or clearance of flurbiprofen.

Likelihood Unlikely Evidence B
The maker

Brand information

Manufacturer and brand details for Ultimate Eye Formula, from the product label.

Woodstock Vitamins

See all Woodstock Vitamins products
Name
Village Vitality LLC
City
Woodstock
State
NY
ZipCode
12498
Web Address
woodstockvitamins.com
Pharmacist Counseling Corner

Ultimate Eye Formula by Woodstock Vitamins: Common Questions

Does Ultimate Eye Formula by Woodstock Vitamins interact with any medications?
Yes. Based on its ingredients, Ultimate Eye Formula has a known interaction with 277 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Ultimate Eye Formula contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this formula actually work for age-related macular degeneration?
Lutein in here has possibly effective evidence for AMD, which is the strongest rating of the three ingredients. Blueberry and bilberry both lack reliable evidence for AMD — the research hasn't established them for eye conditions. Lutein is your best bet in this formula for that specific concern.
Can I take this if I'm pregnant?
All three ingredients are rated likely safe in pregnancy. That said, the safety of concentrated blueberry and bilberry supplements during pregnancy hasn't been deeply studied, so talk with your doctor or pharmacist about whether it's right for you personally.
What side effects might I get?
Blueberry and bilberry can both cause gastrointestinal upset — constipation, diarrhea, nausea, or vomiting with blueberry, and dark stools or flatulence with bilberry. About a quarter of people taking high-dose freeze-dried blueberry dropped out of one trial due to stomach issues. Lutein is well tolerated with no adverse effects reported at typical doses.
Is this safe if I'm breastfeeding?
All three ingredients are rated likely safe while breastfeeding. The safety of high-dose concentrated blueberry and bilberry supplements isn't as well established as food amounts, though, so check with your pharmacist for personalized guidance.
What exactly is lutein and why is it in an eye formula?
Lutein is a plant pigment called a carotenoid that your eyes naturally store in the retina, the light-sensitive tissue at the back of your eye. It's thought to protect eye tissue from damage, and it's the ingredient here with evidence supporting its use for cataracts and age-related macular degeneration.
Will this turn my stools dark?
Yes — bilberry can cause dark-colored or bluish-black stools in some people, and blueberry can too. About half the people in one bilberry study reported dark green stools. This is harmless and should go away when you stop taking the product.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Ultimate Eye Formula is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Ultimate Eye Formula label
Sources

Sources & How We Checked

Ultimate Eye Formula's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 23 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Blueberry 7 references
  1. Cignarella A, Nastasi M, Cavalli E, Puglisi L. Novel lipid-lowering properties of Vaccinium myrtillus L. leaves, a traditional antidiabetic treatment, in several models of rat dyslipidaemia: a comparison with ciprofibrate. Thromb Res 1996;84:311-22. PubMed
  2. Wang SY, Lin HS. Antioxidant activity in fruits and leaves of blackberry, raspberry, and strawberry varies with cultivar and developmental stage. J Agric Food Chem 2000;48:140-6.. PubMed
  3. Martineau, L. C., Couture, A., Spoor, D., Benhaddou-Andaloussi, A., Harris, C., Meddah, B., Leduc, C., Burt, A., Vuong, T., Mai, Le P., Prentki, M., Bennett, S. A., Arnason, J. T., and Haddad, P. S. Anti-diabetic properties of the Canadian lowbush bluebe
  4. Vuong, T., Martineau, L. C., Ramassamy, C., Matar, C., and Haddad, P. S. Fermented Canadian lowbush blueberry juice stimulates glucose uptake and AMP-activated protein kinase in insulin-sensitive cultured muscle cells and adipocytes. Can J Physiol Pharma
  5. Hanley MJ, Masse G, Harmatz JS, Cancalon PF, Dolnikowski GG, Court MH, Greenblatt DJ. Effect of blueberry juice on clearance of buspirone and flurbiprofen in human volunteers. Br J Clin Pharmacol. 2013 Apr;75(4):1041-52. PubMed
  6. Basu A, Du M, Leyva MJ, et al. Blueberries decrease cardiovascular risk factors in obese men and women with metabolic syndrome. J Nutr 2010;140(9):1582-7. PubMed
  7. Basu A, Feng D, Planinic P, Ebersole JL, Lyons TJ, Alexander JM. Dietary blueberry and soluble fiber supplementation reduces risk of gestational diabetes in women with obesity in a randomized controlled trial. J Nutr 2021;151(5):1128-38. PubMed

See these in context on the Blueberry monograph →

Lutein 2 references
  1. Brown L, Rimm EB, Seddon JM, et al. A prospective study of carotenoid intake and risk of cataract extraction in US men. Am J Clin Nutr 1999;70:517-24. PubMed
  2. Chasan-Taber L, Willett WC, Seddon JM, et al. A prospective study of carotenoid and vitamin A intakes and risk of cataract extraction in US women. Am J Clin Nutr 1999;70:509-16. PubMed

See these in context on the Lutein monograph →

Bilberry 14 references
  1. Cignarella A, Nastasi M, Cavalli E, Puglisi L. Novel lipid-lowering properties of Vaccinium myrtillus L. leaves, a traditional antidiabetic treatment, in several models of rat dyslipidaemia: a comparison with ciprofibrate. Thromb Res 1996;84:311-22. PubMed
  2. Morazzoni P, Magistretti MJ. Activity of Myrtocyan, an anthosyanoside complex from Vaccinium myrtillus (VMA), on platelet aggregation and adhesiveness. Fitoterapia 1990;61:13-21.
  3. Erlund, I., Koli, R., Alfthan, G., Marniemi, J., Puukka, P., Mustonen, P., Mattila, P., and Jula, A. Favorable effects of berry consumption on platelet function, blood pressure, and HDL cholesterol. Am J Clin Nutr 2008;87(2):323-331. PubMed
  4. Hawrelak, J. A. and Myers, S. P. Effects of two natural medicine formulations on irritable bowel syndrome symptoms: a pilot study. J Altern Complement Med 2010;16(10):1065-1071. PubMed
  5. Morazzoni P and Magistretti MJ. Effects of Vaccinium myrtillus anthocyanosides on prostacyclin-like activity in rat arterial issue. Fitoterapia 1986;57:11-14.
  6. Pulliero G, Montin S, Bettini V, and et al. Ex vivo study of the inhibitory effects of Vaccinium myrtillus anthocyanosides on human platelet aggregation. Fitoterapia 1989;60:69-75.
  7. Bottecchia D. Preliminary report on the inhibitory effect of vaccinium myrtillus anthocyanosides on platelet aggregation and clot retraction. Fitoterapia 1987;48:3-8.
  8. Fdez, M., Zaragoza, F., and Alvarez, P. In vitro platelet aggregation effects of anthocyanosides of vaccinium myrtilus L. Anales de la Real Academia de Farmacia 1983;49:79-90.
  9. Biedermann L, Mwinyi J, Scharl M, Frei P, Zeitz J, Kullak-Ublick GA, et al. Bilberry ingestion improves disease activity in mild to moderate ulcerative colitis-an open pilot study. 2013 May;7(4):271-9. PubMed
  10. Hoggard N, Cruickshank M, Moar KM, Bestwick C, Holst J, Russell W, et al. A single supplement of a standardized bilberry (Vaccinium myrtillus L.) extract (36% wet weight anthocyanins) modifies glycaemic response in individuals with type 2 diabetes control
  11. Aichinger G, Pahlke G, Nagel LJ, Berger W, Marko D. Bilberry extract, its major phenolic compounds, and soy isoflavone genistein antagonize the cytostatic drug erlotinib in human epithelial cells. Food Funct 2016;7(8):3628-36.
  12. Prokop J, Lněničková K, Cibicek N, et al. Effect of bilberry extract (Vaccinium myrtillus L.) on drug-metabolizing enzymes in rats. Food Chem Toxicol 2019;129:382-90. PubMed
  13. Chan SW, Chu TTW, Choi SW, Benzie IFF, Tomlinson B. Impact of short-term bilberry supplementation on glycemic control, cardiovascular disease risk factors, and antioxidant status in Chinese patients with type 2 diabetes. Phytother Res 2021. Online ahead o PubMed
  14. Bøhn SK, Myhrstad MCW, Thoresen M, et al. Bilberry/red grape juice decreases plasma biomarkers of inflammation and tissue damage in aged men with subjective memory impairment -a randomized clinical trial. BMC Nutr 2021;7(1):75. PubMed

See these in context on the Bilberry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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