No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Usnea Ingredients & Drug Interactions

by Village Vitality

Usnea label
See full label image
Liquid Category: Botanical
No known interaction
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Usnea against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line No known interaction

Usnea is a dietary supplement by Village Vitality with 1 active ingredient. Its ingredients are commonly taken for sore throat, skin and wound care, respiratory infections.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

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HelloPharmacist Scorecard of Usnea by Village Vitality

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: usnea, a lichen used traditionally for cough, pain, and wound healing. It comes as a liquid in a base of grain alcohol and water.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Usnea product and its label doesn't state a use — see Usnea's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold doesn't establish whether usnea works for cough, pain, wound healing, tinea pedis (athlete's foot), or weight management. All of those uses are rated insufficient reliable evidence to rate, meaning studies so far haven't been conclusive enough to say yes or no.

The evidence, ingredient by ingredient Usnea

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Here's what you need to know: usnea taken by mouth may be unsafe because its active compound, usnic acid, has been linked to liver damage. If you do use it topically (on skin), it's generally well tolerated — though some people have reported contact dermatitis, local irritation, conjunctivitis, or allergic reactions with respiratory symptoms.

The safety data for pregnancy and breastfeeding isn't there yet, so the facts advise against use in both. If you're pregnant, nursing, or have liver concerns, talk with your pharmacist or doctor before starting this.

Side effects, ingredient by ingredient Usnea

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for usnea. Still, run it through the medication checker below if you take anything, and let your pharmacist know you're thinking about this supplement.

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Usnea is a traditional herb with very limited evidence backing its uses. If you're considering it for oral use, the liver-safety concern is real and worth discussing with your pharmacist first — topical use appears safer.

Pregnant or nursing folks should avoid it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 23, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Usnea, straight from the product label.

Brand Village Vitality
Barcode (UPC) 788332045516
Net contents 1 Fluid Ounce(s); 30 Milliliter(s)
Market status On market
Date entered into DSLD May 23, 2024
DSLD ID 310330
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Usnea by Village Vitality, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
20 Drop(s)
Maximum serving Sizes:
60 Drop(s)
Servings per container
30
UPC/BARCODE
788332045516
IngredientAmount% DV
Usnea333 mg--

Other ingredients: Grain Alcohol, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: 20 - 60 drops in water or juice, 2 - 3 times daily, or as needed.

Shake well before using.

Precautions

Warning: Keep out of the reach of children.

FDA Statement of Identity

Herbal Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Usnea by Village Vitality label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Usnea label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Usnea by Village Vitality

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size20 Drop(s) Dosage formLiquid Servings per container30 Amounts shown are per serving.

Usnea

No known
interactions
333 mg per serving Form: Usnea barbata

Usnea is a lichen used in traditional herbal medicine, mainly for sore throats, skin infections, and as a general antimicrobial. Laboratory studies su...

Usnea monograph & interactions

Other (inactive) ingredients: Grain Alcohol, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Usnea by Village Vitality Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Usnea. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Usnea, from the product label.

Village Vitality

See all Village Vitality products
Name
Woodstock Apothecary
Street Address
79 Tinker Street
City
Woodstock
State
NY
ZipCode
12498
Pharmacist Counseling Corner

Usnea by Village Vitality: Common Questions

Does Usnea by Village Vitality interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Usnea. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Usnea contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is usnea safe to take by mouth?
The evidence suggests caution. Usnic acid, the active compound in usnea, has been linked to liver damage when taken orally. Topical use (on skin) is generally better tolerated. If you have any liver concerns or take medications, talk with your pharmacist first.
Can I use usnea while pregnant or breastfeeding?
Not enough safety data exists, so the facts advise against it in both cases. Talk with your doctor or pharmacist for personalized advice.
Does usnea actually work for cough or pain?
The evidence we hold doesn't establish that it does. All the common uses — cough, pain, wound healing, and others — are rated insufficient reliable evidence to rate, meaning studies haven't been conclusive enough to confirm it works.
Can usnea cause side effects topically?
Most topical side effects are mild: contact dermatitis, local irritation, or conjunctivitis (eye inflammation) have been reported in some people. Allergic reactions with respiratory symptoms are also possible. If you develop a rash, eye irritation, or breathing trouble, stop and talk with your pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Usnea is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Usnea label
Go deeper

The Full Monographs Behind Usnea’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Usnea

Usnea is a lichen used in traditional herbal medicine, mainly for sore throats, skin infections, and as a general antimicrobial. Laboratory studies suggest its main compound, usnic acid, can...

Read the full Usnea monograph →
Sources

Sources & How We Checked

Usnea's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 10 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Usnea 10 references
  1. Favreau JT, Ryu Ml, Braunstein G, et al. Severe hepatotoxicity associated with the dietary supplement LipoKinetix. Ann Intern Med 2002;136:590-5. PubMed
  2. Ingolfsdottir K. Usnic acid. Phytochemistry 2002;61:729-36.
  3. Scirpa, P., Scambia, G., Masciullo, V., Battaglia, F., Foti, E., Lopez, R., Villa, P., Malecore, M., and Mancuso, S. [A zinc sulfate and usnic acid preparation used as post-surgical adjuvant therapy in genital lesions by Human Papillomavirus]. Minerva Gin
  4. Mitchell, J. C. Allergy to lichens. Allergic contact dermatitis from usnic acid produced by lichenized fungi. Arch Dermatol 1965;92(2):142-146.
  5. Durazo, F. A., Lassman, C., Han, S. H., Saab, S., Lee, N. P., Kawano, M., Saggi, B., Gordon, S., Farmer, D. G., Yersiz, H., Goldstein, R. L., Ghobrial, M., and Busuttil, R. W. Fulminant liver failure due to usnic acid for weight loss. Am.J Gastroenterol. PubMed
  6. Neff, G. W., Reddy, K. R., Durazo, F. A., Meyer, D., Marrero, R., and Kaplowitz, N. Severe hepatotoxicity associated with the use of weight loss diet supplements containing ma huang or usnic acid. J Hepatol. 2004;41(6):1062-1064. PubMed
  7. Hsu, L. M., Huang, Y. S., Chang, F. Y., and Lee, S. D. 'Fat burner' herb, usnic Acid, induced acute hepatitis in a family. J Gastroenterol.Hepatol. 2005;20(7):1138-1139. PubMed
  8. Arneborn, P., Jansson, A., and Bottiger, Y. [Acute hepatitis in a woman after intake of slimming pills bought via Internet]. Lakartidningen 7-11-2005;102(28-29):2071-2072.
  9. Sanchez, W., Maple, J. T., Burgart, L. J., and Kamath, P. S. Severe hepatotoxicity associated with use of a dietary supplement containing usnic acid. Mayo Clin Proc 2006;81(4):541-544. PubMed
  10. Rafanelli, S., Bacchilega, R., Stanganelli, I., and Rafanelli, A. Contact dermatitis from usnic acid in vaginal ovules. Contact Dermatitis 1995;33(4):271-272. PubMed

See these in context on the Usnea monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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