No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Vars Liposomal Glutathione Mint Burst Ingredients & Drug Interactions

by Physician Designed

Liquid Category: Other Combinations
No known interaction
The interaction bottom line No known interaction

Vars Liposomal Glutathione Mint Burst is a dietary supplement by Physician Designed with 2 active ingredients. Its ingredients are commonly taken for liver health, memory and brain support, ulcerative colitis.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Vars Liposomal Glutathione Mint Burst by Physician Designed

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This liquid supplement contains two active ingredients: phosphatidylcholine and phosphatidylethanolamine complex (a type of fat-based compound found in cell membranes) and glutathione (an antioxidant your body makes naturally). The "liposomal" form means the glutathione is wrapped in tiny fat droplets designed to help your body absorb it.

The remaining ingredients are inactive — purified water, sunflower lecithin, polyglycerol esters of fatty acids, natural flavors, lemon oil, peppermint oil, potassium sorbate, sodium benzoate, and stevia leaf extract — they're there for taste, preservation, and delivery.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Antioxidant support and protection.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

For phosphatidylcholine: there's possibly effective evidence it may help with ulcerative colitis (a type of inflammatory bowel disease). For other uses listed — nonalcoholic fatty liver disease, alcohol-related liver disease, Alzheimer's disease, and anxiety — the evidence isn't strong enough to rate.

For glutathione: there's possibly effective evidence for reducing nerve damage (neurotoxicity) from the chemotherapy drug cisplatin. For nonalcoholic fatty liver disease, Alzheimer's disease, athletic performance, and cataracts, the evidence isn't established in our data.

The evidence, ingredient by ingredient Phosphatidylcholine Glutathione

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Phosphatidylcholine is generally well tolerated, but high doses can upset your stomach — bloating, diarrhea, nausea, and vomiting have been reported, especially at very high intakes. Glutathione taken by mouth appears well tolerated short-term, though long-term safety isn't as clear.

During pregnancy, choline (part of phosphatidylcholine) is needed, but supplement safety beyond food sources hasn't been well studied — talk it over with your doctor. For glutathione in pregnancy, there isn't enough reliable safety data, so it's best avoided unless your doctor advises otherwise.

The same caution applies to breastfeeding for both ingredients — check with your healthcare provider first.

Side effects, ingredient by ingredient Phosphatidylcholine Glutathione

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 2 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check in this product. That's a good sign, but it doesn't guarantee none exist — run your specific medications through the checker on this page or confirm with your pharmacist or doctor before you start.

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.

This product might interest you if you're exploring support for ulcerative colitis or chemotherapy-related nerve damage, though the evidence is modest and you should discuss it with your doctor. If you're pregnant or breastfeeding, the safety data on supplements isn't solid enough — talk with your doctor or pharmacist before starting.

Because no drug interactions are documented, it's generally safer to combine with medications than many supplements, but confirm your full routine with your own healthcare provider.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Vars Liposomal Glutathione Mint Burst, straight from the product label.

Brand Physician Designed
Barcode (UPC) 607111481973
Net contents 50 mL; 222 mg
Market status On market
Date entered into DSLD Aug 23, 2021
DSLD ID 249580
Product type Other Combinations
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Vars Liposomal Glutathione Mint Burst by Physician Designed, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1.61 mL
Maximum serving Sizes:
1.61 mL
Servings per container
30
UPC/BARCODE
607111481973
IngredientAmount% DV
Phosphatidylcholine and Phosphatidylethanolamine Complex161 mg--
VARS Glutathione222 mg--

Other ingredients: purified Water, Sunflower Lecithin, Polyglycerol Esters of Fatty Acids, Natural flavors, Lemon Oil, Peppermint Oil, Potassium Sorbate, Sodium Benzoate, Stevia leaf extract

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Vars Mint Burst Liposomal Glutathione Made with setria The power to protect

VARS Patented Liposomal Glutathione is validated, absorbable, reduced, stabilized, and designed by an MD. It delivers up to 222 mg per dose of highly absorbable glutathione in a base of NON-GMO phosphatidylcholine.

VARS Liposomal Glutathione is clinically proven and Made in the USA.

Formulation

Validated absorbable reduced stable

It delivers up to 222 mg per dose of highly absorbable glutathione in a base of NON-GMO phosphatidylcholine.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: Dispense seven complete pumps into mouth, slowly swish and swallow. Do not eat or drink for at least 30 minutes after use. Use as directed by your healthcare professional.

Use within 60 days of opening

Precautions

For adults and children over 4 years old.

For adults and children over 4 years old.

Brand IP Statement(s)

Sertia is a registered trademark of KYOWA HAKKO BIOCO., LTD

Storage

Please keep refrigerated

General Statements

For more information and free eBook download, visit: DanPurserMD.com/how-does-glutathione-work

US Patent #10,272,130

FDA Disclaimer Statement

This product has not been evaluated by the Food and Drug Administration. This product is not intended to treat or diagnose any illness or disease.

See for yourself

Vars Liposomal Glutathione Mint Burst by Physician Designed label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Vars Liposomal Glutathione Mint Burst by Physician Designed

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1.61 mL Dosage formLiquid Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

161 mg per serving Form: non-GMO Sunflower Oil

Phosphatidylcholine is a phospholipid that is part of every cell membrane and a source of choline. People take it for liver, brain, and gut health, bu...

Phosphatidylcholine and Phosphatidylethanolamine Complex monograph & interactions

VARS Glutathione

No known
interactions
222 mg per serving

Glutathione is a powerful antioxidant your body makes naturally, and many people take it as a supplement hoping for skin, detox, or anti-aging benefit...

VARS Glutathione monograph & interactions

Other (inactive) ingredients: Purified Water, Sunflower Lecithin, Polyglycerol Esters of Fatty Acids, Natural flavors, Lemon Oil, Peppermint Oil, Potassium Sorbate, Sodium Benzoate, Stevia leaf extract. These complete the product’s ingredient list but are not active constituents.

Interaction report

Vars Liposomal Glutathione Mint Burst by Physician Designed Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Vars Liposomal Glutathione Mint Burst. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Vars Liposomal Glutathione Mint Burst, from the product label.

Physician Designed

See all Physician Designed products
Name
Professional Nutraceutical Design, LLC
City
Lindon
State
UT
ZipCode
84042
Pharmacist Counseling Corner

Vars Liposomal Glutathione Mint Burst by Physician Designed: Common Questions

Does Vars Liposomal Glutathione Mint Burst by Physician Designed interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Vars Liposomal Glutathione Mint Burst. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Vars Liposomal Glutathione Mint Burst contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take while I'm pregnant?
Glutathione doesn't have enough reliable safety data in pregnancy, so it's best avoided unless your doctor says otherwise. Phosphatidylcholine contains choline, which your body needs in pregnancy, but supplement safety beyond food sources isn't well studied either. Talk with your doctor before taking this product while pregnant.
Can I take this while breastfeeding?
There isn't enough reliable data on either ingredient during breastfeeding, so caution and avoidance are advised. Speak with your healthcare provider first to weigh the benefits and risks for your situation.
What's the difference between regular and liposomal glutathione?
The liposomal form wraps glutathione in tiny fat droplets designed to help your body absorb it better. Your regular oral glutathione isn't packaged that way. Both appear generally well tolerated short-term when taken by mouth.
Will this upset my stomach?
Phosphatidylcholine is usually well tolerated, but higher doses can cause bloating, diarrhea, nausea, and vomiting. Glutathione taken by mouth also appears well tolerated, though long-term side effects aren't fully clear. Start with the dose on the label and see how you feel.
Does this really work for liver disease or Alzheimer's?
The evidence isn't solid enough to rate. Phosphatidylcholine shows possibly effective evidence for ulcerative colitis, and glutathione shows possibly effective evidence for nerve damage from certain chemotherapy drugs — those are the strongest uses supported. For liver disease and Alzheimer's, we don't have reliable evidence either way.
Are there any fillers or additives I should know about?
Yes — besides the two active ingredients, you're getting purified water, sunflower lecithin, natural flavors, lemon and peppermint oils, and preservatives (potassium sorbate and sodium benzoate). Stevia leaf extract adds sweetness. These are all inactive ingredients meant to make the product stable and palatable.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Vars Liposomal Glutathione Mint Burst is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Vars Liposomal Glutathione Mint Burst label
Sources

Sources & How We Checked

Vars Liposomal Glutathione Mint Burst's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 16 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Phosphatidylcholine 15 references
  1. Domino EF, May WW, Demetriou S, et al. Lack of clinically significant improvement of patients with tardive dyskinesia following phosphatidylcholine therapy. Biol Psychiatry 1985;20:1189-96. PubMed
  2. Aronson PJ, Lorincz AL. Promotion of palmar sweating with oral phosphatidylcholine. Acta Derm Venereol 1985;65:19-24. DOI
  3. Hexsel DM, Serra M, de Oliveira Dal'Forno T, et al. Cosmetic uses of injectable phosphatidylcholine on the face. Otolaryngol Clin North Am 2005;38:1119-29. PubMed
  4. Kopera D, Binder B, Toplak H, et al. Histopathologic changes after intralesional application of phosphatidylcholine for lipoma reduction: report of a case. Am J Dermatopathol 2006;28:331-3. PubMed
  5. Rittes PG. The use of phosphatidylcholine for correction of lower lid bulging due to prominent fat pads. Dermatol Surg 2001;27:391-2. PubMed
  6. Rotunda AM, Kolodney MS. Mesotherapy and phosphatidylcholine injections: historical clarification and review. Dermatol Surg 2006;32:465-80. PubMed
  7. Hexsel D, Serra M, Mazzuco R, et al. Phosphatidylcholine in the treatment of localized fat. J Drugs Dermatol 2003;2:511-8.
  8. Hasengschwandtner F. Phosphatidylcholine treatment to induce lipolysis. Cosmet Dermatol 2005;4:308-13. PubMed
  9. Rittes PG. The use of phosphatidylcholine for correction of localized fat deposits. Aesthetic Plast Surg 2003;27:315-8. PubMed
  10. Ablon G, Rotunda AM. Treatment of lower eyelid fat pads using phosphatidylcholine: clinical trial and review. Dermatol Surg 2004;30:422-7. PubMed
  11. Loguercio C, Andreone P, Brisc C, et al. Silybin combined with phosphatidylcholine and vitamin E in patients with nonalcoholic fatty liver disease: a randomized controlled trial. Free Radic Biol Med 2012;52(9):1658-65. PubMed
  12. Panos, J. M., Palson, R., Johnson, R., Portmann, B., and Williams, R. Polyunsaturated phosphatidylcholine for acute alcoholic hepatitis: a double blind randomized placebo controlled trial. Eur.J.Gastroenterol 1990;2:351-355.
  13. Stremmel W, Braun A, Hanemann A, Ehehalt R, Autschbach F, Karner M. Delayed release phosphatidylcholine in chronic-active ulcerative colitis: a randomized, double-blinded, dose finding study. J Clin Gastroenterol 2010;44(5):e101-7. PubMed
  14. Stremmel W, Ehehalt R, Autschbach F, Karner M. Phosphatidylcholine for steroid-refractory chronic ulcerative colitis: a randomized trial. Ann Intern Med. 2007;147(9):603-10. PubMed
  15. Stremmel W, Vural H, Evliyaoglu O, Weiskirchen R. Delayed Release Phosphatidylcholine is Effective for Treatment of Ulcerative Colitis: A Meta-Analysis. Dig Dis 2021;39(5):508-515. PubMed

See these in context on the Phosphatidylcholine monograph →

Glutathione 1 reference
  1. Marrades RM, Roca J, Barbera JA, et al. Nebulized glutathione induces bronchoconstriction in patients with mild asthma. Am J Respir Crit Care Med 1997;156(2 Pt 1):425-30. PubMed

See these in context on the Glutathione monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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