No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Vars Liposomal Glutathione Mint Burst Ingredients & Drug Interactions

by Physician Designed

Liquid Category: Other Combinations
No known interaction
The interaction bottom line No known interaction

Vars Liposomal Glutathione Mint Burst is a dietary supplement by Physician Designed with 2 active ingredients. Its ingredients are commonly taken for liver health, memory and brain support, ulcerative colitis.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Vars Liposomal Glutathione Mint Burst by Physician Designed

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains 2 active ingredients. Phosphatidylcholine is a phospholipid — a compound that supports cell structure and function — and is sometimes used to help with ulcerative colitis and liver health.

Glutathione is an antioxidant your body makes naturally; it's been studied mostly for its potential to protect nerve damage from the chemotherapy drug cisplatin. The rest is inactive ingredients: purified water, sunflower lecithin, polyglycerol esters, natural flavors, lemon and peppermint oils, potassium sorbate, sodium benzoate, and stevia leaf extract.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: antioxidant support and liver health.
  • We looked for evidence on: Aging, Alcohol use disorder, Alcohol-related liver disease, Alzheimer disease, Cardiovascular disease (CVD), Chronic fatigue syndrome (CFS) — and 4 related terms.
  • The closest evidence on file: Phosphatidylcholine is rated "Insufficient Reliable Evidence To Rate" for Alcohol-related liver disease (Natural Medicines).
  • Also on file: Phosphatidylcholine is rated "Insufficient Reliable Evidence To Rate" for Alzheimer disease, Hepatitis A, Dementia, Aging.
  • Also on file: Glutathione is rated "Insufficient Reliable Evidence To Rate" for Alcohol use disorder, Alzheimer disease.

Evidence for these ingredients is mixed. Phosphatidylcholine is possibly effective for ulcerative colitis, but there isn't enough reliable data yet to rate it for nonalcoholic fatty liver disease, alcohol-related liver disease, Alzheimer disease, or anxiety.

Glutathione is possibly effective for nerve damage caused by the chemotherapy drug cisplatin, but evidence is insufficient to rate it for nonalcoholic fatty liver disease, Alzheimer disease, athletic performance, or cataracts.

The evidence, ingredient by ingredient Phosphatidylcholine Glutathione

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Phosphatidylcholine is generally well tolerated in food and supplement amounts, though high doses can cause digestive upset like bloating, diarrhea, nausea, and vomiting. Oral glutathione appears well tolerated short-term, but long-term safety and safety of other forms (IV, inhaled) are less clear.

Inhaled glutathione can narrow airways and cause shortness of breath or cough in people with asthma, so avoid that form if you have asthma. For pregnancy: choline (a related compound in phosphatidylcholine) is needed in pregnancy, but supplement safety beyond food sources isn't well studied — check with your doctor.

Glutathione safety data in pregnancy isn't reliable enough; the data advises against it unless your doctor says otherwise. Breastfeeding data is limited for both ingredients; talk with your healthcare provider first.

Side effects, ingredient by ingredient Phosphatidylcholine Glutathione

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 2 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. Still, if you take any prescription medications, run them through the checker on this page before you start, or ask your pharmacist.

The bottom line

Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

This product combines two ingredients with modest evidence for specific uses — phosphatidylcholine for ulcerative colitis and glutathione for chemotherapy-related nerve damage. If you have either condition or are interested in their antioxidant or liver-support properties, it's worth a conversation with your pharmacist.

If you're pregnant, breastfeeding, or have asthma, check with your doctor or pharmacist first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Vars Liposomal Glutathione Mint Burst, straight from the product label.

Brand Physician Designed
Barcode (UPC) 607111481973
Net contents 50 mL; 222 mg
Market status On market
Date entered into DSLD Aug 23, 2021
DSLD ID 249580
Product type Other Combinations
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Vars Liposomal Glutathione Mint Burst by Physician Designed, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1.61 mL
Maximum serving Sizes:
1.61 mL
Servings per container
30
UPC/BARCODE
607111481973
IngredientAmount% DV
Phosphatidylcholine and Phosphatidylethanolamine Complex161 mg--
VARS Glutathione222 mg--

Other ingredients: purified Water, Sunflower Lecithin, Polyglycerol Esters of Fatty Acids, Natural flavors, Lemon Oil, Peppermint Oil, Potassium Sorbate, Sodium Benzoate, Stevia leaf extract

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Vars Mint Burst Liposomal Glutathione Made with setria The power to protect

VARS Patented Liposomal Glutathione is validated, absorbable, reduced, stabilized, and designed by an MD. It delivers up to 222 mg per dose of highly absorbable glutathione in a base of NON-GMO phosphatidylcholine.

VARS Liposomal Glutathione is clinically proven and Made in the USA.

Formulation

Validated absorbable reduced stable

It delivers up to 222 mg per dose of highly absorbable glutathione in a base of NON-GMO phosphatidylcholine.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: Dispense seven complete pumps into mouth, slowly swish and swallow. Do not eat or drink for at least 30 minutes after use. Use as directed by your healthcare professional.

Use within 60 days of opening

Precautions

For adults and children over 4 years old.

For adults and children over 4 years old.

Brand IP Statement(s)

Sertia is a registered trademark of KYOWA HAKKO BIOCO., LTD

Storage

Please keep refrigerated

General Statements

For more information and free eBook download, visit: DanPurserMD.com/how-does-glutathione-work

US Patent #10,272,130

FDA Disclaimer Statement

This product has not been evaluated by the Food and Drug Administration. This product is not intended to treat or diagnose any illness or disease.

See for yourself

Vars Liposomal Glutathione Mint Burst by Physician Designed label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Vars Liposomal Glutathione Mint Burst by Physician Designed

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1.61 mL Dosage formLiquid Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

161 mg per serving Form: non-GMO Sunflower Oil

Phosphatidylcholine is a phospholipid that is part of every cell membrane and a source of choline. People take it for liver, brain, and gut health, bu...

Phosphatidylcholine and Phosphatidylethanolamine Complex monograph & interactions

VARS Glutathione

No known
interactions
222 mg per serving

Glutathione is a powerful antioxidant your body makes naturally, and many people take it as a supplement hoping for skin, detox, or anti-aging benefit...

VARS Glutathione monograph & interactions

Other (inactive) ingredients: Purified Water, Sunflower Lecithin, Polyglycerol Esters of Fatty Acids, Natural flavors, Lemon Oil, Peppermint Oil, Potassium Sorbate, Sodium Benzoate, Stevia leaf extract. These complete the product’s ingredient list but are not active constituents.

Interaction report

Vars Liposomal Glutathione Mint Burst by Physician Designed Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Vars Liposomal Glutathione Mint Burst. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Vars Liposomal Glutathione Mint Burst, from the product label.

Physician Designed

See all Physician Designed products
Name
Professional Nutraceutical Design, LLC
City
Lindon
State
UT
ZipCode
84042
Pharmacist Counseling Corner

Vars Liposomal Glutathione Mint Burst by Physician Designed: Common Questions

Does Vars Liposomal Glutathione Mint Burst by Physician Designed interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Vars Liposomal Glutathione Mint Burst. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Vars Liposomal Glutathione Mint Burst contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is phosphatidylcholine really effective for ulcerative colitis?
The evidence says it's possibly effective, which means there's some support but it's not definitive. Talk to your gastroenterologist before adding it to your colitis treatment — it shouldn't replace your current medications.
What's glutathione, and why would I take it?
Glutathione is an antioxidant your body makes naturally. This product has been studied mainly for protecting nerve damage caused by the chemotherapy drug cisplatin. Evidence for other uses — like Alzheimer disease or athletic performance — isn't reliable enough to say it works yet.
Can I take this while pregnant?
Phosphatidylcholine contains choline, which is needed in pregnancy, but supplement safety beyond food sources isn't well studied. Glutathione safety in pregnancy isn't established enough; the data advises against it unless your doctor says otherwise. Talk with your doctor before starting.
What side effects might I notice?
Phosphatidylcholine can cause bloating, diarrhea, altered taste, nausea, and vomiting, especially at higher doses. Oral glutathione appears well tolerated short-term, though long-term safety isn't clear. If you have asthma, avoid inhaled glutathione — it can cause airway narrowing and shortness of breath.
Can I take this while breastfeeding?
There isn't enough reliable safety data on either ingredient for breastfeeding. Speak with your healthcare provider first to weigh the pros and cons for your situation.
Does this liquid contain any fillers or additives I should know about?
The inactive ingredients are purified water, sunflower lecithin, polyglycerol esters, natural flavors, lemon and peppermint oils, potassium sorbate, sodium benzoate, and stevia leaf extract. If you're sensitive to any of those — especially sorbate or benzoate — let your pharmacist know.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Vars Liposomal Glutathione Mint Burst is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Vars Liposomal Glutathione Mint Burst label
Sources

Sources & How We Checked

Vars Liposomal Glutathione Mint Burst's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 16 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Phosphatidylcholine 15 references
  1. Domino EF, May WW, Demetriou S, et al. Lack of clinically significant improvement of patients with tardive dyskinesia following phosphatidylcholine therapy. Biol Psychiatry 1985;20:1189-96. PubMed
  2. Aronson PJ, Lorincz AL. Promotion of palmar sweating with oral phosphatidylcholine. Acta Derm Venereol 1985;65:19-24. DOI
  3. Hexsel DM, Serra M, de Oliveira Dal'Forno T, et al. Cosmetic uses of injectable phosphatidylcholine on the face. Otolaryngol Clin North Am 2005;38:1119-29. PubMed
  4. Kopera D, Binder B, Toplak H, et al. Histopathologic changes after intralesional application of phosphatidylcholine for lipoma reduction: report of a case. Am J Dermatopathol 2006;28:331-3. PubMed
  5. Rittes PG. The use of phosphatidylcholine for correction of lower lid bulging due to prominent fat pads. Dermatol Surg 2001;27:391-2. PubMed
  6. Rotunda AM, Kolodney MS. Mesotherapy and phosphatidylcholine injections: historical clarification and review. Dermatol Surg 2006;32:465-80. PubMed
  7. Hexsel D, Serra M, Mazzuco R, et al. Phosphatidylcholine in the treatment of localized fat. J Drugs Dermatol 2003;2:511-8.
  8. Hasengschwandtner F. Phosphatidylcholine treatment to induce lipolysis. Cosmet Dermatol 2005;4:308-13. PubMed
  9. Rittes PG. The use of phosphatidylcholine for correction of localized fat deposits. Aesthetic Plast Surg 2003;27:315-8. PubMed
  10. Ablon G, Rotunda AM. Treatment of lower eyelid fat pads using phosphatidylcholine: clinical trial and review. Dermatol Surg 2004;30:422-7. PubMed
  11. Loguercio C, Andreone P, Brisc C, et al. Silybin combined with phosphatidylcholine and vitamin E in patients with nonalcoholic fatty liver disease: a randomized controlled trial. Free Radic Biol Med 2012;52(9):1658-65. PubMed
  12. Panos, J. M., Palson, R., Johnson, R., Portmann, B., and Williams, R. Polyunsaturated phosphatidylcholine for acute alcoholic hepatitis: a double blind randomized placebo controlled trial. Eur.J.Gastroenterol 1990;2:351-355.
  13. Stremmel W, Braun A, Hanemann A, Ehehalt R, Autschbach F, Karner M. Delayed release phosphatidylcholine in chronic-active ulcerative colitis: a randomized, double-blinded, dose finding study. J Clin Gastroenterol 2010;44(5):e101-7. PubMed
  14. Stremmel W, Ehehalt R, Autschbach F, Karner M. Phosphatidylcholine for steroid-refractory chronic ulcerative colitis: a randomized trial. Ann Intern Med. 2007;147(9):603-10. PubMed
  15. Stremmel W, Vural H, Evliyaoglu O, Weiskirchen R. Delayed Release Phosphatidylcholine is Effective for Treatment of Ulcerative Colitis: A Meta-Analysis. Dig Dis 2021;39(5):508-515. PubMed

See these in context on the Phosphatidylcholine monograph →

Glutathione 1 reference
  1. Marrades RM, Roca J, Barbera JA, et al. Nebulized glutathione induces bronchoconstriction in patients with mild asthma. Am J Respir Crit Care Med 1997;156(2 Pt 1):425-30. PubMed

See these in context on the Glutathione monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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