No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 2 of 4 ingredients. Check your meds →
Dietary supplement

Vegetarian Enzyme Ingredients & Drug Interactions

by Douglas Laboratories

Tablet Or Pill Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Vegetarian Enzyme is a dietary supplement by Douglas Laboratories with 4 active ingredients. Its ingredients are commonly taken for digestion and bloating, muscle soreness and exercise recovery, inflammation and swelling.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Vegetarian Enzyme by Douglas Laboratories

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 4 active ingredients.
  • “Vegetarian Enzyme Concentrate” is listed as a grouped ingredient — the label gives one combined amount (450 mg) without saying how much of each component you get.

This product contains 4 active ingredients: amylase, protease, lipase, and cellulase—all digestive enzymes that help break down different components of food. Amylase breaks down starches, protease breaks down proteins, lipase breaks down fats, and cellulase breaks down fiber.

The tablet also contains several inactive ingredients used as binders, fillers, and the tablet coating.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

The label doesn't state a purpose we can grade — see each ingredient's own graded uses on its monograph instead.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for these enzymes is limited. For protease and lipase, we hold no effectiveness ratings in our data.

Lipase has been studied for inflammatory bowel disease and indigestion, but the research to date is insufficient to establish whether it works for those conditions. We don't have effectiveness information on file for amylase or cellulase.

The evidence, ingredient by ingredient Proteolytic Enzymes (proteases) Lipase

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Protease and lipase are generally well tolerated by most adults, though either can occasionally cause digestive upset or, rarely, allergic reactions. Because protease is found in some laundry products, occupational exposure to airborne protease has rarely triggered allergic rhinitis or asthma in workers.

For lipase specifically, adverse effects haven't been reported in adults, though a complete safety review hasn't been done. During pregnancy, protease safety hasn't been established and is best avoided unless prescribed by your doctor.

Lipase has little safety data in pregnancy—use it only if your doctor advises. Both ingredients have limited data during breastfeeding; check with your healthcare provider before using if you're nursing.

Side effects, ingredient by ingredient Proteolytic Enzymes (proteases) Lipase

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 2 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we were able to check. However, we could not verify amylase or cellulase, so run your exact medications through the search tool on this page to be certain.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.

This enzyme blend is well tolerated by most adults and may help with digestion, though the evidence for its effectiveness isn't strong. It's a reasonable option if you're looking for a digestive aid, but pregnant or nursing individuals should talk with their doctor or pharmacist first.

If you take any medications, check them against the interaction tool on this page before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Vegetarian Enzyme, straight from the product label.

Brand Douglas Laboratories
Barcode (UPC) 310539002285
Net contents 120 Tablet(s)
Market status On market
Date entered into DSLD Feb 25, 2021
DSLD ID 245429
Product type Non-nutrient/non-botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Vegetarian Enzyme by Douglas Laboratories, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Tablet(s)
Maximum serving Sizes:
2 Tablet(s)
Servings per container
60
UPC/BARCODE
310539002285
IngredientAmount% DV
Amylase0 NP--
Protease0 NP--
Lipase0 NP--
Cellulase0 NP--
Vegetarian Enzyme Concentrate450 mg--

Other ingredients: Microcrystalline Cellulose, Hydroxypropyl Cellulose, Coating, Stearic Acid, Croscarmellose Sodium, Vegetable Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Usage: As a dietary supplement, adults take 2 tablets with each meal, or as directed by your health professional.

Precautions

Warning: If you are pregnant, nursing, have any health condition or taking any medication, consult your health professional before using this product.

Keep out of the reach of children.

Use only if safety seal is intact.

Storage

Store in a cool, dry place.

Formulation

Gluten-free, Non-GMO

Digestive health

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity. Scan to learn about our manufacturing excellence

FDA Statement of Identity

Dietary Supplement

See for yourself

Vegetarian Enzyme by Douglas Laboratories label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Vegetarian Enzyme by Douglas Laboratories

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Tablet(s) Dosage formTablet Or Pill Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Vegetarian Enzyme Concentrate

450 mg per serving

Other (inactive) ingredients: Microcrystalline Cellulose, Hydroxypropyl Cellulose, Coating, Stearic Acid, Croscarmellose Sodium, Vegetable Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Vegetarian Enzyme by Douglas Laboratories Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Vegetarian Enzyme. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Vegetarian Enzyme, from the product label.

Douglas Laboratories

See all Douglas Laboratories products
Name
Douglas Laboratories
Street Address
600 Boyce Road
City
Pittsburgh
State
PA
ZipCode
15205
Phone Number
1.800.245.4440
Web Address
www.douglaslabs.com
Pharmacist Counseling Corner

Vegetarian Enzyme by Douglas Laboratories: Common Questions

Does Vegetarian Enzyme by Douglas Laboratories interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Vegetarian Enzyme. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Vegetarian Enzyme contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while pregnant?
Protease safety in pregnancy hasn't been established and is best avoided unless your doctor prescribes it. Lipase has very little safety data in pregnancy. There's no information on file for amylase or cellulase during pregnancy. Talk with your doctor or pharmacist about whether this product is right for you.
Is it safe while breastfeeding?
Both protease and lipase have limited safety data during breastfeeding and aren't recommended without medical advice. We don't have information on amylase or cellulase while nursing. Check with your healthcare provider before using if you're breastfeeding.
What are these enzymes supposed to do?
Digestive enzymes help break down food into smaller pieces so your body can absorb nutrients. Amylase works on starches, protease on proteins, lipase on fats, and cellulase on fiber. The idea is to ease digestion, though the evidence for these specific supplements is limited.
Can this help with indigestion or bloating?
Lipase has been studied for indigestion, but the research so far is insufficient to say whether it actually works. The same goes for inflammatory bowel disease. If you have a serious digestive condition, use this product only under medical guidance.
What side effects might I experience?
Most people tolerate these enzymes well. Occasionally, digestive upset or allergic reactions can occur. Protease is used in some laundry detergents; rarely, airborne exposure has triggered allergic symptoms in workers, though that's not a concern with supplements taken by mouth.
Are there any fillers or inactive ingredients I should know about?
Yes, the tablet includes microcrystalline cellulose, hydroxypropyl cellulose, stearic acid, croscarmellose sodium, vegetable stearate, silica, and a coating. These are standard inactive ingredients used to hold the tablet together and help it dissolve.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Vegetarian Enzyme is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Vegetarian Enzyme label
Sources

Sources & How We Checked

Vegetarian Enzyme's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring