No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 4 of 20 ingredients. Check your meds →
Dietary supplement

Vital-Zymes Complete Ingredients & Drug Interactions

by Klaire Labs

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Vital-Zymes Complete is a dietary supplement by Klaire Labs with 20 active ingredients. Its ingredients are commonly taken for digestive support, bloating and gas, fat digestion.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Vital-Zymes Complete by Klaire Labs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 20 active ingredients.
  • “Fat Specific Enzymes” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.
  • “Protein and Peptide Specific Enzymes” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.
  • “Other Enzymes” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.

Vital-Zymes Complete contains 20 active ingredients, all digestive enzymes designed to help break down different components of food. The formula includes carbohydrate-digesting enzymes (amylase, glucoamylase, maltase, sucrase), fat-digesting lipase, protein-digesting proteases (acid protease and alkaline protease), and several others targeting fiber, sugar, and more complex carbohydrates.

The inactive ingredients are a vegetarian capsule, coconut oil powder, and cellulose.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: comprehensive digestive enzyme support.
  • We looked for evidence on: Dyspepsia, Lactose intolerance, bloating and gas, indigestion, fat malabsorption.
  • The strongest evidence on file: Lactase is rated "Effective" for Lactose intolerance (Natural Medicines).
  • Also on file: Lipase is rated "Insufficient Reliable Evidence To Rate" for Dyspepsia.

Lactase in this formula is rated effective for lactose intolerance. The other enzymes — lipase, acid protease, alkaline protease, and phytase — do not have established evidence in our data for the conditions they're marketed to address; the evidence is either insufficient or not yet rated.

The formula as a whole lacks a documented effectiveness rating for general digestive support.

The evidence, ingredient by ingredient Lipase Proteolytic Enzymes (proteases) Lactase Phytase

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactase is generally well tolerated and likely safe in pregnancy. Lipase, acid protease, alkaline protease, and phytase are all generally well tolerated in adults, though protease enzymes may occasionally cause digestive upset or allergic reactions.

Rare cases of occupational airborne exposure to protease and phytase have triggered allergic rhinitis (stuffy nose and itchy eyes), asthma, and hypersensitivity lung inflammation — these occurred in industrial settings with powdered enzyme exposure, not typical supplement use. In pregnancy, safety data are limited for lipase and phytase; acid protease and alkaline protease have not been established as safe during pregnancy, so avoid them unless your doctor prescribes.

During breastfeeding, check with your doctor or pharmacist first, as data are sparse for most ingredients. Premature infants should not receive this product without medical supervision.

Side effects, ingredient by ingredient Lipase Proteolytic Enzymes (proteases) Lactase Phytase

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 4 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. That said, we could not verify interaction data for roughly half of the enzyme ingredients in this formula.

If you take any prescription medications, use the medication checker on this page with your specific drugs, or ask your pharmacist to review the full ingredient list.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

If you have lactose intolerance, Lactase here is evidence-backed. For general digestive support, the evidence isn't established in our data.

If you're pregnant or breastfeeding, or have a serious digestive condition, talk to your doctor or pharmacist before starting — the safety picture is incomplete for several ingredients. Check your exact medications with the tool on this page.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 20 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Vital-Zymes Complete, straight from the product label.

Brand Klaire Labs
Barcode (UPC) 790616310005
Net contents 120 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Jan 23, 2023
DSLD ID 281272
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Vital-Zymes Complete by Klaire Labs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
60
UPC/BARCODE
790616310005
IngredientAmount% DV
Amylase0 NP--
Serratiopeptidase0 NP--
Lipase0 NP--
Lactase0 NP--
Cellulase0 NP--
Glucoamylase0 NP--
Alpha-Galactosidase0 NP--
Maltase0 NP--
Acid Protease0 NP--
Beta-Glucanase0 NP--
Phytase0 NP--
Alpha-Amylase0 NP--
Sucrase0 NP--
Alkaline Protease0 NP--
Lysozyme0 NP--
Comprehensive Enzyme Blend800 mg--
Pullulanase0 NP--
Hemicellulase/Pectinase/Phytase Complex0 NP--
Galactomannase0 NP--
Fat Specific Enzymes0 NP--
Protein and Peptide Specific Enzymes0 NP--
Protease/Peptidase Complex0 NP--
Other Enzymes0 NP--
Carbohydrate Specific Enzymes0 NP--
Sugar Specific Enzymes0 NP--
Vegetable/Plant Fiber Specific Enzymes0 NP--

Other ingredients: Vegetarian Capsule, Coconut Oil, Powder, Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Comprehensive Enzyme Supplement

Brand IP Statement(s)

SFI

Peptizyme SP, a registered trademark of Specialty Enzymes

Precautions

Caution: If you are pregnant, nursing, have a medical condition, taking prescription drugs, or are allergic to eggs, consult your healthcare professional before using this product.

Caution: If you are pregnant, nursing, have a medical condition, taking prescription drugs, or are allergic to eggs, consult your healthcare professional before using this product.

Keep out of reach of children.

Do not use if shrinkwrap is broken or missing.

Formulation

Free of the following common allergens: milk/casein, fish, shellfish, peanuts, wheat, gluten, and soybeans. Contains no artificial colors, flavors, or preservatives.

Produced under a strict quality management system in compliance with Good Manufacturing Practices (GMP) and third-party quality certifications.

Suggested/Recommended/Usage/Directions

Suggested use: 2 capsules at the beginning of each meal or as directed by a healthcare professional.

General Statements

Units are those used in edition five (V) of the Food Chemicals Codex (FCC)

Storage

Store in a cool, dry place (59 degrees F-85 degrees F) away from direct light.

See for yourself

Vital-Zymes Complete by Klaire Labs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Vital-Zymes Complete by Klaire Labs

These are the 20 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Comprehensive Enzyme Blend

800 mg per serving

Fat Specific Enzymes

0 NP per serving

Protein and Peptide Specific Enzymes

0 NP per serving

Other Enzymes

0 NP per serving
  • › Serratiopeptidase
  • › Lysozyme

Carbohydrate Specific Enzymes

0 NP per serving
  • › Amylase
  • › Glucoamylase
  • › Alpha-Amylase

Sugar Specific Enzymes

0 NP per serving
  • Lactase
  • › Maltase
  • › Sucrase
  • › Pullulanase

Vegetable/Plant Fiber Specific Enzymes

0 NP per serving
  • › Cellulase
  • › Alpha-Galactosidase
  • › Beta-Glucanase
  • Phytase
  • › Hemicellulase/Pectinase/Phytase Complex
  • › Galactomannase

Other (inactive) ingredients: Vegetarian Capsule, Coconut Oil, Powder, Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Vital-Zymes Complete by Klaire Labs Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Vital-Zymes Complete. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Vital-Zymes Complete, from the product label.

Klaire Labs

See all Klaire Labs products
Name
SFI USA
City
Reno
State
NV
ZipCode
89521
Web Address
Klaire.com
Pharmacist Counseling Corner

Vital-Zymes Complete by Klaire Labs: Common Questions

Does Vital-Zymes Complete by Klaire Labs interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Vital-Zymes Complete. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Vital-Zymes Complete contains 20 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help with bloating and gas?
These enzymes are meant to break down food components that can cause bloating, but we don't have established evidence in our data showing this formula works for that purpose. Results vary person to person. If you're having ongoing digestive trouble, it's worth checking in with your doctor.
Is it safe to take if I'm pregnant?
Safety data are limited or not established for several ingredients here during pregnancy. Lipase, acid protease, and alkaline protease all lack solid pregnancy safety information. Talk to your doctor before starting — they can tell you whether it's right for you.
Can I take this if I'm breastfeeding?
Safety while breastfeeding hasn't been well studied for most of these enzymes. Check with your doctor or pharmacist first to make sure it's okay for your situation.
What is Lactase in this formula for?
Lactase helps your body digest lactose, the natural sugar in milk and dairy products. It's rated effective for lactose intolerance — if you have trouble digesting dairy, this ingredient is evidence-backed.
Are there any fillers in this?
The inactive ingredients are a vegetarian capsule, coconut oil powder, and cellulose. Those are the only non-active ingredients in the formula.
Is this safe for people with serious digestive conditions?
If you have inflammatory bowel disease or another serious digestive condition, use this only under medical guidance. Talk to your doctor first to make sure it's appropriate for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Vital-Zymes Complete is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Vital-Zymes Complete label
Sources

Sources & How We Checked

Vital-Zymes Complete's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Lactase 1 reference
  1. Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed

See these in context on the Lactase monograph →

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Phytase 7 references
  1. Lei XG, Weaver JD, Mullaney E, Ullah AH, Azain MJ. Phytase, a new life for an "old" enzyme. Annu Rev Anim Biosci. 2013;1:283-309. PubMed
  2. Smuts CM, Matsungo TM, Malan L, et al. Effect of small-quantity lipid-based nutrient supplements on growth, psychomotor development, iron status, and morbidity among 6- to 12-mo-old infants in South Africa: a randomized controlled trial. Am J Clin Nutr. 2 PubMed
  3. van Heemst RC, Sander I, Rooyackers J, et al. Hypersensitivity pneumonitis caused by occupational exposure to phytase. Eur Respir J. 2009;33(6):1507-9. PubMed
  4. Baur X, Melching-Kollmuss S, Koops F, Strassburger K, Zober A. IgE-mediated allergy to phytase -- a new animal feed additive. Allergy. 2002;57(10):943-5. PubMed
  5. Doekes G, Kamminga N, Helwegen L, Heederik D. Occupational IgE sensitisation to phytase, a phosphatase derived from Aspergillus niger. Occup Environ Med. 1999;56(7):454-9. PubMed
  6. Brnic M, Hurrell RF, Songré-Ouattara LT, et al. Effect of phytase on zinc absorption from a millet-based porridge fed to young Burkinabe children. Eur J Clin Nutr. 2017;71(1):137-141. PubMed
  7. Koshy JC, Sharabi SE, Feldman EM, Hollier LH Jr, Patrinely JR, Soparkar CN. Effect of dietary zinc and phytase supplementation on botulinum toxin treatments. J Drugs Dermatol. 2012;11(4):507-12.

See these in context on the Phytase monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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