No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Witch Hazel Ingredients & Drug Interactions

by Hawaii Pharm

Liquid Category: Botanical
No known interaction
The interaction bottom line No known interaction

Witch Hazel is a dietary supplement by Hawaii Pharm with 1 active ingredient. Its ingredients are commonly taken for skin irritation and inflammation, hemorrhoids, minor cuts and bruises.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Witch Hazel by Hawaii Pharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: wildcrafted witch hazel extract. Witch hazel is a plant-derived astringent—a substance that causes tissue to tighten—traditionally used for skin concerns.

The inactive ingredients are vegetable palm glycerin and pharmaceutical-grade alcohol, which serve as the liquid base and preservative.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: skin health and minor irritation relief.
  • We looked for evidence on: Acne, Atopic dermatitis (eczema), Bruises, Hemorrhoids, Insect bite, Skin irritation — and 3 related terms.
  • The strongest evidence on file: Witch Hazel is rated "Possibly Effective" for Hemorrhoids (Natural Medicines).
  • Also on file: Witch Hazel is rated "Possibly Ineffective" for Atopic dermatitis (eczema).
  • Also on file: Witch Hazel is rated "Insufficient Reliable Evidence To Rate" for Acne, Skin irritation, Sunburn, Insect bite, and more.

Witch hazel is possibly effective for hemorrhoids. For atopic dermatitis (eczema), the evidence rates it as possibly ineffective.

For varicose veins and postmenopausal conditions, there isn't enough reliable evidence yet to know whether it works.

The evidence, ingredient by ingredient Witch Hazel

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Topically, witch hazel is generally well tolerated. The most common side effect when applied to skin is contact dermatitis—redness or burning in a small number of people.

This product is not meant to be taken by mouth. If you do take it orally, it's generally well tolerated at normal doses, but high doses carry a risk of kidney and liver damage because of the tannin content (the leaf and bark contain 8% to 12% tannins).

There's also mixed evidence around tannins and cancer risk; some suggest regular high-dose consumption of tannin-rich herbs may correlate with increased esophageal or nasal cancer.

Side effects, ingredient by ingredient Witch Hazel

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for the ingredients we could check in this product.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Witch hazel is a topical option worth trying if you're dealing with hemorrhoids. Keep it on your skin and out of your mouth.

If you have kidney or liver concerns, or if you're thinking about taking it internally, talk to your pharmacist or doctor first. And if you develop redness or burning where you apply it, stop and let us know.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Witch Hazel, straight from the product label.

Brand Hawaii Pharm
Barcode (UPC) 650905471070
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Oct 23, 2020
DSLD ID 237848
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Witch Hazel by Hawaii Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.7 mL
Maximum serving Sizes:
1 mL
Servings per container
120
UPC/BARCODE
650905471070
IngredientAmount% DV
wildcrafted Witch Hazel extract970 mg--

Other ingredients: Vegetable Palm Glycerin, pharmaceutical grade Alcohol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Hawaii Pharm Herbal Extract Highest quality since 2008

Made with Aloha!

Formulation

Contains no GMO, gluten, artificial colors, heavy metals, preservatives, pesticides, fertilizers.

Super concentrated liquid herbal extract. Dry herb/menstruum ratio: 1:3.

Manufactured in an FDA registered facility.

Non GMO Gluten free

Made in USA, Hawaii

Suggested/Recommended/Usage/Directions

Directions for use: Shake well before using. Take about 20-30 drops (0.7-1 ml, one full squeeze of the dropper bulb) to 2-4 oz of juice or water up to 4 times per day.

Precautions

Warning: Keep out of the reach of children.

May have contraindications. We recommend to seek expert medical advice before taking.

Do not use if you are allergic to any ingredients.

Consult a physician before using during pregnancy, if nursing or taking any medications.

Do not use if seal is broken or missing.

Storage

Store in a cool dry place.

Formula

(Hamamelis virginiana)

FDA Statement of Identity

Herbal Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

FDA Registered Facility Made in United States of America USA

See for yourself

Witch Hazel by Hawaii Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Witch Hazel by Hawaii Pharm

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.7 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.

Wildcrafted Witch Hazel extract

No known
interactions
970 mg per serving

Witch hazel is a plant-based astringent used mostly on the skin for minor irritation, hemorrhoids, and oily skin. It is generally well tolerated as a...

Wildcrafted Witch Hazel extract monograph & interactions

Other (inactive) ingredients: Vegetable Palm Glycerin, Pharmaceutical grade Alcohol. These complete the product’s ingredient list but are not active constituents.

Interaction report

Witch Hazel by Hawaii Pharm Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Witch Hazel. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Witch Hazel, from the product label.

Hawaii Pharm

See all Hawaii Pharm products
Name
Hawaii Pharm LLC
City
Honolulu
State
HI
ZipCode
96815
Web Address
www.hawaiipharm.com
Pharmacist Counseling Corner

Witch Hazel by Hawaii Pharm: Common Questions

Does Witch Hazel by Hawaii Pharm interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Witch Hazel. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Witch Hazel contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I use witch hazel while I'm pregnant?
The safety data available to us doesn't provide clear guidance on pregnancy use. Topically it's likely low risk, but we'd recommend asking your doctor or pharmacist for personalized advice before using it while pregnant.
Is it safe to use witch hazel while breastfeeding?
Safety data for breastfeeding isn't on file for this ingredient. If you're thinking about topical use, check with your doctor or pharmacist first—and definitely avoid applying it to the nipple area.
What's the most common side effect if I use it on my skin?
Contact dermatitis—redness or burning—is the most common side effect when applied topically. A small number of people experience it. If that happens to you, stop using it and reach out to us.
Can I drink witch hazel?
This product is not meant to be taken by mouth. If you do take it orally at normal doses, it's generally well tolerated, but high doses can damage your kidneys and liver because of how much tannin is in the plant. Talk to your doctor first if you're considering that.
Does witch hazel work for eczema?
The evidence suggests it's possibly ineffective for atopic dermatitis (eczema), so it's not a reliable choice for that condition.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Witch Hazel is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Witch Hazel label
Go deeper

The Full Monographs Behind Witch Hazel’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Witch Hazel's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Witch Hazel 7 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  3. Robbers JE, Tyler VE. Tyler's Herbs of Choice: The Therapeutic Use of Phytomedicinals. New York, NY: The Haworth Herbal Press, 1999.
  4. Hormann HP, Korting HC. Evidence for the efficacy and safety of topical herbal drugs in dermatology: part I: anti-inflammatory agents. Phytomedicine 1994;1:161-71. PubMed
  5. Wolff, H. H. and Kieser, M. Hamamelis in children with skin disorders and skin injuries: results of an observational study. Eur.J.Pediatr. 2007;166(9):943-948. PubMed
  6. Khanna, N. and Datta, Gupta S. Rejuvenating facial massage--a bane or boon? Int J Dermatol. 2002;41(7):407-410. PubMed
  7. Theisen LL, Erdelmeier CA, Spoden GA, Boukhallouk F, Sausy A, Florin L, Muller CP. Tannins from Hamamelis virginiana bark extract: characterization and improvement of the antiviral efficacy against influenza A virus and human papillomavirus. PLoS One. 201 PubMed

See these in context on the Witch Hazel monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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