No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Yucca 500 mg Ingredients & Drug Interactions

by NOW

Capsule Category: Botanical
No known interaction
The interaction bottom line No known interaction

Yucca 500 mg is a dietary supplement by NOW with 1 active ingredient. Its ingredients are commonly taken for joint pain and arthritis, digestive health, high cholesterol.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Yucca 500 mg by NOW

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: yucca root concentrate at 500 mg per capsule. Yucca is a plant extract that's been used traditionally for joint support and other purposes.

The capsule also holds three inactive ingredients—hypromellose, magnesium stearate, and stearic acid—which are common binders and capsule materials.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Yucca's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: herbal supplement from traditional use.
  • We looked for evidence on: Hypercholesterolemia, Hypertension, Joint pain, Arthritis, Inflammation, Digestive health.
  • The closest evidence on file: Yucca is rated "Insufficient Reliable Evidence To Rate" for Hypercholesterolemia (Natural Medicines).
  • Also on file: Yucca is rated "Insufficient Reliable Evidence To Rate" for Hypertension, Joint pain.

The evidence for yucca doesn't yet support a clear rating. For bleeding, joint pain, and dandruff, we hold insufficient reliable evidence to say whether it works.

That doesn't mean it doesn't—it means the clinical trials we have aren't strong enough yet to draw a solid conclusion either way.

The evidence, ingredient by ingredient Yucca

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Yucca is generally well tolerated in food amounts, though supplement safety hasn't been studied extensively. The safety data we hold advises against use during pregnancy and breastfeeding because there isn't enough information to know either way.

Some people have developed allergic reactions after environmental or occupational exposure to yucca—allergic rhinitis (hay-fever-like symptoms) from inhalation, and contact urticaria (itchy welts) or phytodermatitis (plant-caused skin inflammation) from skin contact. If you have a known plant allergy or sensitive skin, mention this product to your doctor or pharmacist before starting.

Side effects, ingredient by ingredient Yucca

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredient we could check. That said, it's always smart to mention any new supplement to your pharmacist, especially if you're on medications for chronic conditions.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

Yucca 500 mg is a single-ingredient supplement with no documented drug interactions. If you're interested in yucca for joint support or other uses, the evidence isn't yet established, so talk with your pharmacist about whether it fits your situation.

Pregnancy, breastfeeding, and a history of plant allergies are reasons to check with your doctor first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Yucca 500 mg, straight from the product label.

Brand NOW
Barcode (UPC) 733739047809
Net contents 100 Veg. Capsule(s)
Market status On market
Date entered into DSLD Jul 25, 2024
DSLD ID 314223
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Yucca 500 mg by NOW, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Veg Capsule(s)
Maximum serving Sizes:
2 Veg Capsule(s)
Servings per container
50
UPC/BARCODE
733739047809
IngredientAmount% DV
Total Carbohydrates1 Gram(s)1%
Yucca Root Concentrate1 Gram(s)--

Other ingredients: Hypromellose, Magnesium Stearate, Stearic Acid

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Usage: Take 2 capsules 1 to 3 times daily.

Formula

Yucca is a popular herb from a shrub which grows in the southwest U.S. deserts. It has been used by Native American herbalists for hundreds of years.

Naturally Occurring Saponins

Triangle K (Kosher)

Precautions

Caution: For adults only.

Consult physician if pregnant/nursing, taking medication, or have a medical condition.

Keep out of reach of children.

Not manufactured with yeast, wheat, gluten, soy, milk, egg, fish, shellfish, tree nut or sesame ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Formulation

Natural color variation may occur in this product.

Herbal Supplement

Non-GMO

Vegetarian/Vegan

Made and quality tested in the USA with globally sourced ingredients.

Not manufactured with yeast, wheat, gluten, soy, milk, egg, fish, shellfish, tree nut or sesame ingredients.

General Statements

This bottle is made from 100% PCR (post-consumer recycled) resin.

Botanicals/Herbs Family owned since 1968.

FDA Statement of Identity

A Dietary Supplement

Seals/Symbols

Triangle K (Kosher)

GMP Quality Assured

Storage

Store in a cool, dry place after opening.

See for yourself

Yucca 500 mg by NOW label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Yucca 500 mg by NOW

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Veg Capsule(s) Dosage formCapsule Servings per container50 Amounts shown are per serving.

Yucca Root Concentrate

No known
interactions
1 Gram(s) per serving

Yucca is a desert plant traditionally used for joint pain, arthritis, and digestion, and it contains compounds called saponins thought to have anti-in...

Yucca Root Concentrate monograph & interactions

Other (inactive) ingredients: Hypromellose, Magnesium Stearate, Stearic Acid. These complete the product’s ingredient list but are not active constituents.

Interaction report

Yucca 500 mg by NOW Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Yucca 500 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Yucca 500 mg, from the product label.

NOW

See all NOW products
Name
NOW FOODS
Street Address
395 S. Glen Ellyn Rd.
City
Bloomingdale
State
IL
ZipCode
60108
Web Address
nowfoods.com
Pharmacist Counseling Corner

Yucca 500 mg by NOW: Common Questions

Does Yucca 500 mg by NOW interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Yucca 500 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Yucca 500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is yucca safe during pregnancy or while breastfeeding?
The safety data advises against use during pregnancy and breastfeeding because there isn't enough information to know either way. Talk with your doctor or pharmacist for personalized advice.
Can yucca cause allergic reactions?
Yes. Some people have developed allergic rhinitis (hay-fever-like symptoms) from breathing yucca dust, and contact urticaria (itchy welts) or skin inflammation from touching yucca plants. If you have a history of plant allergies or sensitive skin, mention this to your doctor before starting.
Does yucca really help with joint pain?
The evidence we hold is insufficient to say whether it works. That means the clinical trials so far aren't strong enough to draw a solid conclusion either way.
What's in the capsule besides yucca?
The capsule contains three inactive ingredients: hypromellose, magnesium stearate, and stearic acid. These are common binders and capsule materials.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Yucca 500 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Yucca 500 mg label
Go deeper

The Full Monographs Behind Yucca 500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Yucca 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Yucca 3 references
  1. <p><span>Kanerva, L., Estlander, T., Petman, L., Makinen-Kiljunen, S. Occupational allergic contact urticaria to yucca (Yucca aloifolia), weeping fig (Ficus benjamina), and spathe flower (Spathiphyllum wallisii). Allergy. 2001;56(10): 1008-11.</span></p>
  2. Poljacki, M., Paravina, M., Jovanovic, M., Subotic, M., and Duran, V. [Contact allergic dermatitis caused by plants]. Med Pregl. 1993;46(9-10):371-375.
  3. Mahillon, V., Saussez, S., and Michel, O. High incidence of sensitization to ornamental plants in allergic rhinitis. Allergy 2006;61(9):1138-1140. PubMed

See these in context on the Yucca monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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