Zi Su Zi Ingredients & Drug Interactions
by Herbal Terra
What is this page for?
First and foremost: checking Zi Su Zi against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Zi Su Zi is a dietary supplement by Herbal Terra with 1 active ingredient. Its ingredients are commonly taken for seasonal and food allergies, asthma and airway inflammation, atopic dermatitis (eczema).We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Zi Su Zi by Herbal Terra
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: certified organic Zi Su Zi (Perilla frutescens) dried leaf liquid extract. Perilla is a plant used in traditional medicine and cooking.
The inactive ingredient is menstruum, a liquid carrier used to extract and deliver the herb.
Does it work?
Insufficient evidence
The evidence for Perilla does not yet support its use for any of the conditions listed on the label — age-related cognitive decline, allergic rhinitis (hay fever), asthma, osteoporosis, cancer, and headache all show insufficient reliable evidence. That means either there's not enough good research, or the research that exists doesn't point in one direction.
We simply don't have the data to say whether it works for these purposes.
How safe is it?
Well-documented data
Perilla is generally well tolerated when used as a food, but supplement-strength products haven't been well studied, so caution is wise. The most common topical side effect is dermatitis (skin irritation).
Oral use is uncommon, but there is a rare serious risk: anaphylaxis (a severe allergic reaction) has been reported in both adults and children who consumed perilla seeds, and some research points to oleosin as the likely culprit. Occupational asthma has also been reported from breathing smoke from roasted perilla seeds.
During pregnancy and breastfeeding, there isn't enough safety data — the facts advise against medicinal amounts at these times. Talk with your doctor or pharmacist to weigh whether this is right for you if you're pregnant, nursing, or have a known allergy to perilla.
Meds to double-check
No known interactions
No interactions are documented in our data for Perilla. Still, if you take any medications regularly, it's wise to run them through the checker on this page or ask your pharmacist — we can only speak to what we've reviewed.
The bottom line
Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
Zi Su Zi is a single-ingredient herbal extract with no documented drug interactions, but also no solid evidence of effectiveness for the conditions on the label. It's generally well tolerated when used as a food, though supplement-strength products lack robust safety study.
If you have a history of severe allergies or are pregnant or breastfeeding, check with your pharmacist first.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Zi Su Zi, straight from the product label.
| Brand | Herbal Terra |
|---|---|
| Barcode (UPC) | 738600508823 |
| Net contents | 4 Fluid Ounce(s); 120 mL |
| Market status | On market |
| Date entered into DSLD | Sep 25, 2020 |
| DSLD ID | 234432 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Organic, Gluten Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Zi Su Zi by Herbal Terra, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| certified organic Zi Su Zi (Perilla frutescens) dried leaf liquid extract | 970 mg | -- |
Other ingredients: Menstruum
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Direction Shake well before use. Adults take up to 30 drops (1 mL, one full squeeze of the dropper bulb) in 3-4 fl. oz of juice or water up to 4 times a day. We recommend to seek expert medical advice before taking this or any other herbal supplements.
FDA Disclaimer Statement
Notice This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure, or prevent any disease.
Formulation
Manufactured in the USA in an FDA registered facility
Sugar free
Dried herb/menstruum ratio: 1:3 Expertly extracted Laboratory tested 330 mg/1 mL Premium product Super concentrated liquid herbal extract
Non GMO
No artificial ingredients, GMO, gluten, color additives, fillers, preservatives or binders. Natural Gluten Free
Precautions
Caution May have contraindications.
Do not use if you are allergic to any ingredients.
Consult a physician before using during pregnancy, if nursing, or if you are on any medications.
Keep out of the reach of children.
Storage
Store in a cool, dry, dark place.
Formula
Perilla frutescens
FDA Statement of Identity
Herbal Supplement
Seals/Symbols
Made in USA Made in an FDA registered facility Natural Gluten Free
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Zi Su Zi by Herbal Terra label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Zi Su Zi by Herbal Terra
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.
Certified organic Zi Su Zi (Perilla frutescens) dried leaf liquid extract
No knowninteractions
Perilla is an Asian mint-family plant used in cooking and traditional medicine, mainly for allergy, breathing, and digestive complaints. Most human ev...
Certified organic Zi Su Zi (Perilla frutescens) dried leaf liquid extract monograph & interactionsOther (inactive) ingredients: Menstruum. These complete the product’s ingredient list but are not active constituents.
Zi Su Zi by Herbal Terra Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Zi Su Zi. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Zi Su Zi, from the product label.
Zi Su Zi by Herbal Terra: Common Questions
Does Zi Su Zi by Herbal Terra interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is Zi Su Zi safe to take while I'm pregnant?
Can I use this if I'm breastfeeding?
Does Perilla actually work for hay fever or asthma?
What are the side effects I should watch for?
I have a tree nut or seed allergy — is this safe for me?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Zi Su Zi is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Zi Su Zi’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Zi Su Zi's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 4 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Perilla 4 references
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- Kanzaki, T. and Kimura, S. Occupational allergic contact dermatitis from Perilla frutescens (shiso). Contact Dermatitis 1992;26(1):55-56.
- Yu H, Qiu JF, Ma LJ, Hu YJ, Li P, Wan JB. Phytochemical and phytopharmacological review of Perilla frutescens L. (Labiatae), a traditional edible-medicinal herb in China. Food Chem Toxicol 2017;108(Pt B):375-91. PubMed
- Jeong K, Lee SY, Jeon SA, et al. Clinical and immunological characterization of perilla seed allergy in children. J Investig Allergol Clin Immunol 2021. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC