Butabarbital

Generic name: Pronounced as (byoo ta bar' bi tal)
Brand names
  • Butabarb®
  • Butalan®
  • Buticaps®
  • Butisol® Sodium
  • Sarisol®
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Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 04/15/2019

Butabarbital is used on a short-term basis to treat insomnia (difficulty falling asleep or staying asleep). It is also used to relieve anxiety, including anxiety before surgery. Butabarbital is in a class of medications called barbiturates. It works by slowing activity in the brain.

Butabarbital comes as a tablet and a solution (liquid) to take by mouth. When butabarbital is used to treat insomnia, it is usually taken at bedtime as needed for sleep. When butabarbital is used to relieve anxiety before surgery, it is usually taken 60 to 90 minutes before surgery. When butabarbital is used to relieve anxiety, it is usually taken three to four times a day. If you are taking butabarbital on a regular schedule, take it at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take butabarbital exactly as directed.

Your sleep problems should improve within 7 to 10 days after you start taking butabarbital. Call your doctor if your sleep problems do not improve during this time, if they get worse at any time during your treatment, or if you notice any changes in your thoughts or behavior.

Butabarbital should normally be taken for short periods of time. If you take butabarbital for 2 weeks or longer, butabarbital may not help you sleep as well or control your anxiety as it did when you first began to take the medication. If you take butabarbital for a long time, you also may develop dependence ('addiction,' a need to continue taking the medication) on butabarbital. Talk to your doctor about the risks of taking butabarbital for 2 weeks or longer. Do not take a larger dose of butabarbital, take it more often, or take it for a longer time than prescribed by your doctor.

Do not stop taking butabarbital without talking to your doctor. Your doctor will probably decrease your dose gradually. If you suddenly stop taking butabarbital, you may develop anxiety, muscle twitching, uncontrollable shaking of your hands or fingers, weakness, dizziness, changes in vision, nausea, vomiting, or difficulty falling asleep or staying asleep, or you may experience more severe withdrawal symptoms such as seizures or extreme confusion.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking butabarbital,

  • tell your doctor and pharmacist if you are allergic to butabarbital; other barbiturates such as amobarbital (Amytal, in Tuinal), pentobarbital, phenobarbital, or secobarbital (Seconal); tartrazine (a yellow dye found in some foods and medications); aspirin; or any other medications. Ask your pharmacist for a list of the ingredients.

  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: anticoagulants ('blood thinners') such as warfarin (Coumadin, Jantoven); antihistamines; doxycycline (Doryx, Vibramycin; Vibra-tabs); griseofulvin (Fulvicin-U/F, Grifulvin V, Gris-PEG); hormone replacement therapy; monoamine oxidase (MAO) inhibitors such as isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate); medications for depression, pain, colds or allergies; muscle relaxants; certain medications for seizures such as phenytoin (Dilantin) and valproic acid (Depakene); oral steroids such as dexamethasone, methylprednisolone (Medrol), and prednisone; sedatives; sleeping pills; and tranquilizers. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

  • tell your doctor if you have or have ever had porphyria (condition in which certain natural substances build up in the body and may cause stomach pain, changes in thinking and behavior, and other symptoms). Your doctor will probably tell you not to take butabarbital.

  • tell your doctor if you drink or have ever drunk large amounts of alcohol, use or have ever used street drugs, or have overused prescription medications. Also tell your doctor if you have ever thought about killing yourself or tried to do so and if you have or have ever had asthma or any condition that causes shortness of breath or difficulty breathing; depression; seizures; or kidney or liver disease.

  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking butabarbital, call your doctor immediately. Butabarbital may harm the fetus.

  • you should know that butabarbital may decrease the effectiveness of hormonal contraceptives (birth control pills, patches, rings, injections, implants, or intrauterine devices). Talk to your doctor about methods of birth control that will work for you during your treatment with butabarbital. Tell your doctor if you have a missed period or think you may be pregnant while you are taking butabarbital.

  • talk to your doctor about the risks and benefits of taking this medication if you are 65 years of age or older. Older adults should not usually take butabarbital because it is not as safe or effective as other medication(s) that can be used to treat the same condition.

  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking butabarbital.

  • you should know that this medication may make you drowsy during the daytime, may decrease your mental alertness, and may increase the risk that you could fall. Take extra care to be sure you do not fall, especially if you get out of bed in the middle of the night. Do not drive a car or operate machinery until you know how this medication affects you.

  • do not drink alcohol during your treatment with butabarbital. Alcohol can make the side effects of butabarbital worse.

  • you should know that some people who took medications for sleep got out of bed and drove their cars, prepared and ate food, had sex, made phone calls, or were involved in other activities while partially asleep. After they woke up, these people were usually unable to remember what they had done. Call your doctor right away if you find out that you have been driving or doing anything else while you were sleeping.

Unless your doctor tells you otherwise, continue your normal diet.

If you are taking butabarbital on a regular basis, take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

  • Butabarbital may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • drowsiness

    • difficulty falling asleep or staying asleep

    • nightmares

    • headache

    • dizziness

    • depression

    • nervousness

    • agitation

    • excitement

    • confusion

    • restlessness

    • nausea

    • vomiting

    • constipation

  • Some side effects can be serious. If you experience any of the following symptoms, or those listed in the SPECIAL PRECAUTIONS sections, call your doctor immediately:

    • hallucinating (seeing things or hearing voices that do not exist)

    • slow, shallow breathing

    • slow heartbeat

    • fainting

    • hives

    • rash

    • itching

    • swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs

    • difficulty breathing or swallowing

    • hoarseness

  • Butabarbital may cause other side effects. Tell your doctor if you have any unusual problems while you are taking this medication.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Symptoms of overdose may include:

  • unsteadiness

  • slurred speech

  • uncontrollable eye movements

  • confusion

  • poor judgment

  • irritability

  • difficulty falling asleep or staying asleep

  • fast, slowed or shallow breathing

  • narrowed pupils (black circles in the middle of the eye)

  • decreased urination

  • fast heartbeat

  • low body temperature

  • coma (loss of consciousness for a periol of time)

Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your response to butabarbital.

Do not let anyone else take your medication. Butabarbital is a controlled substance. Prescriptions may be refilled only a limited number of times; ask your pharmacist if you have any questions.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

  • secbutobarabitone sodium

Drug Interaction
Dolasetron Dolasetron The risk or severity of adverse effects can be increased when Butabarbital is combined with Dolasetron.
Aminophylline Aminophylline The therapeutic efficacy of Butabarbital can be decreased when used in combination with Aminophylline.
Bisacodyl Bisacodyl The therapeutic efficacy of Bisacodyl can be decreased when used in combination with Butabarbital.
Cilostazol Cilostazol Butabarbital may decrease the excretion rate of Cilostazol which could result in a higher serum level.
Diphenoxylate Diphenoxylate The risk or severity of adverse effects can be increased when Butabarbital is combined with Diphenoxylate.
Estrogen and Progestin (Oral Contraceptives) Estrogen and Progestin (Oral Contraceptives) Butabarbital may decrease the excretion rate of Conjugated estrogens which could result in a higher serum level.
Fenofibrate Fenofibrate Butabarbital may decrease the excretion rate of Fenofibrate which could result in a higher serum level.
Guanfacine Guanfacine The risk or severity of adverse effects can be increased when Butabarbital is combined with Guanfacine.
Magnesium Hydroxide Magnesium Hydroxide Butabarbital may decrease the excretion rate of Magnesium hydroxide which could result in a higher serum level.
Magnesium Oxide Magnesium Oxide The therapeutic efficacy of Magnesium oxide can be decreased when used in combination with Butabarbital.
Mycophenolate Mycophenolate Butabarbital may decrease the excretion rate of Mycophenolic acid which could result in a higher serum level.
Naratriptan Naratriptan The risk or severity of adverse effects can be increased when Butabarbital is combined with Naratriptan.
Olsalazine Olsalazine Olsalazine may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Paregoric Paregoric The risk or severity of adverse effects can be increased when Butabarbital is combined with Morphine.
Penbutolol Penbutolol Butabarbital may increase the hypotensive activities of Acebutolol.
Pentazocine Pentazocine The risk or severity of adverse effects can be increased when Butabarbital is combined with Pentazocine.
Polyethylene glycol-electrolyte solution (PEG-ES) Polyethylene glycol-electrolyte solution (PEG-ES) The therapeutic efficacy of Polyethylene glycol can be decreased when used in combination with Butabarbital.
Potassium Potassium Potassium may increase the excretion rate of Butabarbital which could result in a lower serum level and potentially a reduction in efficacy.
Prednisone Prednisone Butabarbital may decrease the excretion rate of Prednisone which could result in a higher serum level.
Psyllium Psyllium The therapeutic efficacy of Plantago seed can be decreased when used in combination with Butabarbital.
Ranitidine Ranitidine Butabarbital may decrease the excretion rate of Ranitidine which could result in a higher serum level.
Reserpine Reserpine The risk or severity of adverse effects can be increased when Reserpine is combined with Butabarbital.
Rizatriptan Rizatriptan The risk or severity of adverse effects can be increased when Butabarbital is combined with Rizatriptan.
Sumatriptan Sumatriptan The risk or severity of adverse effects can be increased when Butabarbital is combined with Sumatriptan.
Tacrolimus Tacrolimus Tacrolimus may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Tizanidine Tizanidine The risk or severity of adverse effects can be increased when Butabarbital is combined with Tizanidine.
Zolmitriptan Zolmitriptan The risk or severity of adverse effects can be increased when Butabarbital is combined with Zolmitriptan.
Ampicillin Injection Ampicillin Injection Butabarbital may decrease the excretion rate of Ampicillin which could result in a higher serum level.
Doxycycline Injection Doxycycline Injection The serum concentration of Doxycycline can be decreased when it is combined with Butabarbital.
Fluconazole Injection Fluconazole Injection Fluconazole may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Foscarnet Injection Foscarnet Injection Foscarnet may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Hydromorphone Injection Hydromorphone Injection The risk or severity of adverse effects can be increased when Butabarbital is combined with Hydromorphone.
Levofloxacin Injection Levofloxacin Injection Butabarbital may decrease the excretion rate of Levofloxacin which could result in a higher serum level.
Meperidine Injection Meperidine Injection Butabarbital may increase the hypotensive and central nervous system depressant (CNS depressant) activities of Meperidine.
Metoclopramide Injection Metoclopramide Injection The risk or severity of sedation can be increased when Metoclopramide is combined with Butabarbital.
Morphine Injection Morphine Injection The risk or severity of adverse effects can be increased when Butabarbital is combined with Morphine.
Pamidronate Injection Pamidronate Injection Pamidronic acid may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Vancomycin Injection Vancomycin Injection Butabarbital may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Altretamine Altretamine The risk or severity of adverse effects can be increased when Amphetamine is combined with Butabarbital.
Cefuroxime Cefuroxime Cefuroxime may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Cyclosporine Cyclosporine The metabolism of Butabarbital can be increased when combined with Cyclosporine.
Ondansetron Ondansetron The risk or severity of adverse effects can be increased when Butabarbital is combined with Ondansetron.
Granisetron Granisetron The risk or severity of adverse effects can be increased when Butabarbital is combined with Granisetron.
Torsemide Torsemide Torasemide may increase the excretion rate of Butabarbital which could result in a lower serum level and potentially a reduction in efficacy.
Olanzapine Olanzapine The risk or severity of adverse effects can be increased when Butabarbital is combined with Olanzapine.
Alosetron Alosetron The risk or severity of adverse effects can be increased when Butabarbital is combined with Alosetron.
Entacapone Entacapone The risk or severity of adverse effects can be increased when Butabarbital is combined with Entacapone.
Eprosartan Eprosartan Butabarbital may increase the hypotensive activities of Eprosartan.
Meloxicam Meloxicam Meloxicam may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Oxcarbazepine Oxcarbazepine The risk or severity of adverse effects can be increased when Butabarbital is combined with Oxcarbazepine.
Pantoprazole Pantoprazole Pantoprazole may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Telmisartan Telmisartan Butabarbital may increase the hypotensive activities of Telmisartan.
Temozolomide Temozolomide Butabarbital may decrease the excretion rate of Temozolomide which could result in a higher serum level.
Zaleplon Zaleplon The risk or severity of adverse effects can be increased when Butabarbital is combined with Zaleplon.
Desloratadine Desloratadine The risk or severity of adverse effects can be increased when Butabarbital is combined with Desloratadine.
Linezolid Linezolid The risk or severity of adverse effects can be increased when Butabarbital is combined with Linezolid.
Rivastigmine Rivastigmine The therapeutic efficacy of Butabarbital can be decreased when used in combination with Rivastigmine.
Trimipramine Trimipramine The risk or severity of adverse effects can be increased when Butabarbital is combined with Trimipramine.
Glycopyrrolate Glycopyrrolate Butabarbital may increase the central nervous system depressant (CNS depressant) activities of Glycopyrronium.
Perindopril Perindopril Perindopril may increase the hypotensive activities of Butabarbital.
Tenofovir Tenofovir Tenofovir may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Choline Magnesium Trisalicylate Choline Magnesium Trisalicylate Choline magnesium trisalicylate may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Eplerenone Eplerenone Eplerenone may increase the excretion rate of Butabarbital which could result in a lower serum level and potentially a reduction in efficacy.
Escitalopram Escitalopram The risk or severity of adverse effects can be increased when Butabarbital is combined with Escitalopram.
Olmesartan Olmesartan Butabarbital may increase the hypotensive activities of Olmesartan.
Zonisamide Zonisamide The risk or severity of adverse effects can be increased when Butabarbital is combined with Zonisamide.
Aripiprazole Aripiprazole The risk or severity of adverse effects can be increased when Butabarbital is combined with Aripiprazole.
Atomoxetine Atomoxetine The risk or severity of adverse effects can be increased when Butabarbital is combined with Atomoxetine.
Dexmethylphenidate Dexmethylphenidate The risk or severity of adverse effects can be increased when Butabarbital is combined with Dexmethylphenidate.
Atazanavir Atazanavir Atazanavir may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Almotriptan Almotriptan The risk or severity of adverse effects can be increased when Butabarbital is combined with Almotriptan.
Eletriptan Eletriptan The risk or severity of adverse effects can be increased when Eletriptan is combined with Butabarbital.
Mefloquine Mefloquine The therapeutic efficacy of Butabarbital can be decreased when used in combination with Mefloquine.
Polyethylene Glycol 3350 Polyethylene Glycol 3350 The therapeutic efficacy of Polyethylene glycol can be decreased when used in combination with Butabarbital.
Emtricitabine Emtricitabine Butabarbital may decrease the excretion rate of Emtricitabine which could result in a higher serum level.
Memantine Memantine The therapeutic efficacy of Butabarbital can be decreased when used in combination with Memantine.
Tegaserod Tegaserod The therapeutic efficacy of Tegaserod can be decreased when used in combination with Butabarbital.
Tadalafil Tadalafil Butabarbital may decrease the excretion rate of Tadalafil which could result in a higher serum level.
Frovatriptan Frovatriptan The risk or severity of adverse effects can be increased when Butabarbital is combined with Frovatriptan.
Apomorphine Injection Apomorphine Injection The risk or severity of adverse effects can be increased when Butabarbital is combined with Apomorphine.
Protriptyline Protriptyline The risk or severity of adverse effects can be increased when Butabarbital is combined with Protriptyline.
Duloxetine Duloxetine The risk or severity of adverse effects can be increased when Butabarbital is combined with Duloxetine.
Tinidazole Tinidazole Butabarbital may decrease the excretion rate of Tinidazole which could result in a higher serum level.
Trospium Trospium Butabarbital may increase the central nervous system depressant (CNS depressant) activities of Trospium.
Cefditoren Cefditoren Butabarbital may decrease the excretion rate of Cefdinir which could result in a higher serum level.
Cyanocobalamin Injection Cyanocobalamin Injection Hydroxocobalamin may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Eszopiclone Eszopiclone The risk or severity of CNS depression can be increased when Butabarbital is combined with Eszopiclone.
Ganciclovir Ganciclovir Butabarbital may decrease the excretion rate of Ganciclovir which could result in a higher serum level.
Ribavirin Ribavirin Butabarbital may decrease the excretion rate of Ribavirin which could result in a higher serum level.
Solifenacin Solifenacin Butabarbital may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Valganciclovir Valganciclovir Butabarbital may decrease the excretion rate of Valganciclovir which could result in a higher serum level.
Voriconazole Voriconazole The serum concentration of Voriconazole can be decreased when it is combined with Butabarbital.
Adefovir Adefovir Adefovir may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Dextroamphetamine Dextroamphetamine The risk or severity of adverse effects can be increased when Amphetamine is combined with Butabarbital.
Sodium Oxybate Sodium Oxybate Butabarbital may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate.
Isocarboxazid Isocarboxazid The risk or severity of adverse effects can be increased when Butabarbital is combined with Isocarboxazid.
Ramelteon Ramelteon The risk or severity of adverse effects can be increased when Butabarbital is combined with Ramelteon.
Darifenacin Darifenacin Butabarbital may increase the central nervous system depressant (CNS depressant) activities of Darifenacin.
Fentanyl Fentanyl The risk or severity of adverse effects can be increased when Butabarbital is combined with Fentanyl.
Pregabalin Pregabalin The therapeutic efficacy of Butabarbital can be increased when used in combination with Pregabalin.
Felbamate Felbamate The serum concentration of Felbamate can be increased when it is combined with Butabarbital.
Ranolazine Ranolazine Butabarbital may decrease the excretion rate of Ranolazine which could result in a higher serum level.
Rasagiline Rasagiline The risk or severity of adverse effects can be increased when Butabarbital is combined with Rasagiline.
Sitagliptin Sitagliptin Butabarbital may decrease the excretion rate of Sitagliptin which could result in a higher serum level.
Varenicline Varenicline Butabarbital may decrease the excretion rate of Varenicline which could result in a higher serum level.
Albuterol Albuterol Butabarbital may decrease the excretion rate of Salbutamol which could result in a higher serum level.
Paliperidone Paliperidone The risk or severity of adverse effects can be increased when Butabarbital is combined with Paliperidone.
Clofarabine Injection Clofarabine Injection Butabarbital may increase the hypotensive activities of Clofarabine.
Lubiprostone Lubiprostone Butabarbital may decrease the excretion rate of Lubiprostone which could result in a higher serum level.
Aliskiren Aliskiren Butabarbital may increase the hypotensive activities of Aliskiren.
Pemetrexed Injection Pemetrexed Injection Butabarbital may decrease the excretion rate of Pemetrexed which could result in a higher serum level.
Dimenhydrinate Dimenhydrinate The risk or severity of adverse effects can be increased when Butabarbital is combined with Dimenhydrinate.
Nabilone Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Butabarbital.
Sorafenib Sorafenib Butabarbital may decrease the excretion rate of Sorafenib which could result in a higher serum level.
Dronabinol Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Butabarbital.
Levocetirizine Levocetirizine The risk or severity of adverse effects can be increased when Butabarbital is combined with Levocetirizine.
Pegaptanib Injection Pegaptanib Injection Butabarbital may decrease the excretion rate of Pegaptanib which could result in a higher serum level.
Azacitidine Injection Azacitidine Injection Butabarbital may decrease the excretion rate of Azacitidine which could result in a higher serum level.
Paclitaxel (with polyoxyethylated castor oil) Injection Paclitaxel (with polyoxyethylated castor oil) Injection The therapeutic efficacy of Castor oil can be decreased when used in combination with Butabarbital.
Lenalidomide Lenalidomide Butabarbital may decrease the excretion rate of Lenalidomide which could result in a higher serum level.
Budesonide Budesonide Butabarbital may decrease the excretion rate of Budesonide which could result in a higher serum level.
Chloramphenicol Injection Chloramphenicol Injection The metabolism of Butabarbital can be decreased when combined with Chloramphenicol.
Desmopressin Desmopressin Desmopressin may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Betaine Betaine The therapeutic efficacy of Butabarbital can be decreased when used in combination with Glycine betaine.
OnabotulinumtoxinA Injection OnabotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Butabarbital is combined with Botulinum toxin type A.
RimabotulinumtoxinB Injection RimabotulinumtoxinB Injection The risk or severity of adverse effects can be increased when Butabarbital is combined with Botulinum Toxin Type B.
Doripenem Injection Doripenem Injection Butabarbital may decrease the excretion rate of Doripenem which could result in a higher serum level.
Arsenic Trioxide Injection Arsenic Trioxide Injection Butabarbital may increase the hypotensive activities of Arsenic trioxide.
Desvenlafaxine Desvenlafaxine The risk or severity of adverse effects can be increased when Butabarbital is combined with Desvenlafaxine.
Cevimeline Cevimeline Cevimeline may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Nebivolol Nebivolol Butabarbital may increase the hypotensive activities of Nebivolol.
Tretinoin Tretinoin Butabarbital may increase the hypotensive activities of Tretinoin.
Certolizumab Injection Certolizumab Injection Butabarbital may decrease the excretion rate of Certolizumab pegol which could result in a higher serum level.
Daptomycin Injection Daptomycin Injection Daptomycin may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Methylnaltrexone Injection Methylnaltrexone Injection Butabarbital may decrease the excretion rate of Methylnaltrexone which could result in a higher serum level.
Rufinamide Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Butabarbital.
Midazolam Midazolam The risk or severity of adverse effects can be increased when Butabarbital is combined with Midazolam.
Naltrexone Injection Naltrexone Injection The risk or severity of adverse effects can be increased when Butabarbital is combined with Naltrexone.
Dexrazoxane Injection Dexrazoxane Injection Butabarbital may decrease the excretion rate of Dexrazoxane which could result in a higher serum level.
Milnacipran Milnacipran The risk or severity of adverse effects can be increased when Butabarbital is combined with Milnacipran.
Plerixafor Injection Plerixafor Injection Butabarbital may decrease the excretion rate of Plerixafor which could result in a higher serum level.
Sodium Phosphate Sodium Phosphate The therapeutic efficacy of Sodium phosphate, monobasic can be decreased when used in combination with Butabarbital.
Fesoterodine Fesoterodine Butabarbital may increase the central nervous system depressant (CNS depressant) activities of Fesoterodine.
Betaxolol Betaxolol Butabarbital may increase the hypotensive activities of Betaxolol.
Iloperidone Iloperidone The risk or severity of adverse effects can be increased when Butabarbital is combined with Iloperidone.
Prasugrel Prasugrel Butabarbital may decrease the excretion rate of Prasugrel which could result in a higher serum level.
Lacosamide Lacosamide The risk or severity of adverse effects can be increased when Butabarbital is combined with Lacosamide.
Tolvaptan (low blood sodium) Tolvaptan (low blood sodium) Tolvaptan may increase the excretion rate of Butabarbital which could result in a lower serum level and potentially a reduction in efficacy.
AbobotulinumtoxinA Injection AbobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Butabarbital is combined with Botulinum toxin type A.
Pralatrexate Injection Pralatrexate Injection Butabarbital may decrease the excretion rate of Pralatrexate which could result in a higher serum level.
Palonosetron Injection Palonosetron Injection The risk or severity of adverse effects can be increased when Butabarbital is combined with Palonosetron.
Saxagliptin Saxagliptin Butabarbital may decrease the excretion rate of Saxagliptin which could result in a higher serum level.
Telavancin Injection Telavancin Injection Butabarbital may decrease the excretion rate of Telavancin which could result in a higher serum level.
Tapentadol Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Butabarbital.
Topotecan Topotecan Butabarbital may decrease the excretion rate of Topotecan which could result in a higher serum level.
Asenapine Asenapine The risk or severity of adverse effects can be increased when Butabarbital is combined with Asenapine.
Vigabatrin Vigabatrin The risk or severity of adverse effects can be increased when Butabarbital is combined with Vigabatrin.
Ulipristal Ulipristal The serum concentration of Ulipristal can be decreased when it is combined with Butabarbital.
Oxymorphone Oxymorphone The risk or severity of adverse effects can be increased when Butabarbital is combined with Oxymorphone.
Dalfampridine Dalfampridine Butabarbital may decrease the excretion rate of Dalfampridine which could result in a higher serum level.
IncobotulinumtoxinA Injection IncobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Butabarbital is combined with Botulinum toxin type A.
Ceftaroline Injection Ceftaroline Injection Ceftaroline fosamil may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Lurasidone Lurasidone The risk or severity of adverse effects can be increased when Butabarbital is combined with Lurasidone.
Acetaminophen Injection Acetaminophen Injection The metabolism of Acetaminophen can be increased when combined with Butabarbital.
Vilazodone Vilazodone The risk or severity of adverse effects can be increased when Butabarbital is combined with Vilazodone.
Ipilimumab Injection Ipilimumab Injection Butabarbital may decrease the excretion rate of Ipilimumab which could result in a higher serum level.
Denileukin Diftitox Injection Denileukin Diftitox Injection Aldesleukin may increase the hypotensive activities of Butabarbital.
Terbutaline Injection Terbutaline Injection The therapeutic efficacy of Butabarbital can be decreased when used in combination with Terbutaline.
Azilsartan Azilsartan Butabarbital may increase the hypotensive activities of Azilsartan medoxomil.
Roflumilast Roflumilast Butabarbital may decrease the excretion rate of Roflumilast which could result in a higher serum level.
Rivaroxaban Rivaroxaban Butabarbital may decrease the excretion rate of Rivaroxaban which could result in a higher serum level.
Ruxolitinib Ruxolitinib Butabarbital may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Clobazam Clobazam The risk or severity of adverse effects can be increased when Butabarbital is combined with Clobazam.
Deferiprone Deferiprone Butabarbital may decrease the excretion rate of Deferiprone which could result in a higher serum level.
Cabergoline Cabergoline The risk or severity of adverse effects can be increased when Butabarbital is combined with Cabergoline.
Naloxone Injection Naloxone Injection Butabarbital may decrease the excretion rate of Naloxone which could result in a higher serum level.
Fondaparinux Injection Fondaparinux Injection Butabarbital may decrease the excretion rate of Fondaparinux which could result in a higher serum level.
Ezogabine Ezogabine The risk or severity of adverse effects can be increased when Butabarbital is combined with Tiagabine.
Iloprost Iloprost Butabarbital may increase the hypotensive activities of Iloprost.
Enzalutamide Enzalutamide Butabarbital may decrease the excretion rate of Enzalutamide which could result in a higher serum level.
Mirabegron Mirabegron Butabarbital may decrease the excretion rate of Mirabegron which could result in a higher serum level.
Linaclotide Linaclotide The therapeutic efficacy of Linaclotide can be decreased when used in combination with Butabarbital.
Teduglutide Injection Teduglutide Injection Butabarbital may decrease the excretion rate of Teduglutide which could result in a higher serum level.
Alogliptin Alogliptin Butabarbital may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Pomalidomide Pomalidomide The risk or severity of adverse effects can be increased when Butabarbital is combined with Pomalidomide.
Canagliflozin Canagliflozin The serum concentration of Canagliflozin can be decreased when it is combined with Butabarbital.
Methazolamide Methazolamide Methazolamide may increase the excretion rate of Butabarbital which could result in a lower serum level and potentially a reduction in efficacy.
Trametinib Trametinib Butabarbital may decrease the excretion rate of Trametinib which could result in a higher serum level.
Levomilnacipran Levomilnacipran The risk or severity of adverse effects can be increased when Butabarbital is combined with Levomilnacipran.
Ertapenem Injection Ertapenem Injection Butabarbital may decrease the excretion rate of Ertapenem which could result in a higher serum level.
Vortioxetine Vortioxetine The risk or severity of adverse effects can be increased when Butabarbital is combined with Vortioxetine.
Perampanel Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Butabarbital.
Ketorolac Injection Ketorolac Injection Ketorolac may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Obinutuzumab Injection Obinutuzumab Injection Butabarbital may increase the hypotensive activities of Obinutuzumab.
Sofosbuvir Sofosbuvir Butabarbital may decrease the excretion rate of Sofosbuvir which could result in a higher serum level.
Dapagliflozin Dapagliflozin Dapagliflozin may increase the excretion rate of Butabarbital which could result in a lower serum level and potentially a reduction in efficacy.
Apremilast Apremilast Butabarbital may decrease the excretion rate of Apremilast which could result in a higher serum level.
Droxidopa Droxidopa Butabarbital may decrease the excretion rate of Droxidopa which could result in a higher serum level.
Eslicarbazepine Eslicarbazepine The risk or severity of adverse effects can be increased when Butabarbital is combined with Eslicarbazepine.
Testosterone Injection Testosterone Injection Butabarbital may decrease the excretion rate of Testosterone which could result in a higher serum level.
Empagliflozin Empagliflozin Butabarbital may increase the hypotensive activities of Empagliflozin.
Hydrocodone Hydrocodone Butabarbital may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone.
Suvorexant Suvorexant Butabarbital may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Edoxaban Edoxaban Butabarbital may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Methamphetamine Methamphetamine The risk or severity of adverse effects can be increased when Butabarbital is combined with Metamfetamine.
Tasimelteon Tasimelteon The risk or severity of adverse effects can be increased when Butabarbital is combined with Tasimelteon.
Riociguat Riociguat Butabarbital may increase the hypotensive activities of Riociguat.
Risperidone Injection Risperidone Injection The risk or severity of adverse effects can be increased when Butabarbital is combined with Risperidone.
Dinutuximab Injection Dinutuximab Injection Butabarbital may increase the hypotensive activities of Dinutuximab.
Haloperidol Injection Haloperidol Injection The risk or severity of CNS depression can be increased when Butabarbital is combined with Haloperidol.
Amiloride Amiloride Amiloride may increase the excretion rate of Butabarbital which could result in a lower serum level and potentially a reduction in efficacy.
Macitentan Macitentan Butabarbital may decrease the excretion rate of Macitentan which could result in a higher serum level.
Flibanserin Flibanserin The risk or severity of adverse effects can be increased when Butabarbital is combined with Flibanserin.
Brexpiprazole Brexpiprazole The risk or severity of adverse effects can be increased when Butabarbital is combined with Brexpiprazole.
Ziprasidone Injection Ziprasidone Injection The risk or severity of adverse effects can be increased when Butabarbital is combined with Ziprasidone.
Cariprazine Cariprazine The risk or severity of adverse effects can be increased when Butabarbital is combined with Cariprazine.
Penicillin G Procaine Injection Penicillin G Procaine Injection Butabarbital may decrease the excretion rate of Procaine benzylpenicillin which could result in a higher serum level.
Eluxadoline Eluxadoline The risk or severity of constipation can be increased when Butabarbital is combined with Eluxadoline.
Ixazomib Ixazomib Butabarbital may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Lesinurad Lesinurad Butabarbital may decrease the excretion rate of Lesinurad which could result in a higher serum level.
Amphotericin B Liposomal Injection Amphotericin B Liposomal Injection Amphotericin B may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Brivaracetam Injection Brivaracetam Injection The risk or severity of adverse effects can be increased when Butabarbital is combined with Brivaracetam.
Pimavanserin Pimavanserin The risk or severity of adverse effects can be increased when Butabarbital is combined with Pimavanserin.
Diphenhydramine Injection Diphenhydramine Injection The risk or severity of adverse effects can be increased when Butabarbital is combined with Diphenhydramine.
Furosemide Injection Furosemide Injection Butabarbital may increase the excretion rate of Furosemide which could result in a lower serum level and potentially a reduction in efficacy.
Lixisenatide Injection Lixisenatide Injection Butabarbital may decrease the excretion rate of Lixisenatide which could result in a higher serum level.
Doxepin (Insomnia) Doxepin (Insomnia) Butabarbital may increase the central nervous system depressant (CNS depressant) activities of Doxepin.
Plecanatide Plecanatide The therapeutic efficacy of Plecanatide can be decreased when used in combination with Butabarbital.
Deutetrabenazine Deutetrabenazine The risk or severity of sedation and somnolence can be increased when Butabarbital is combined with Deutetrabenazine.
Valbenazine Valbenazine Butabarbital may decrease the excretion rate of Valbenazine which could result in a higher serum level.
Safinamide Safinamide The risk or severity of adverse effects can be increased when Butabarbital is combined with Safinamide.
Naldemedine Naldemedine Butabarbital may decrease the excretion rate of Naldemedine which could result in a higher serum level.
Benznidazole Benznidazole Butabarbital may decrease the excretion rate of Benznidazole which could result in a higher serum level.
Delafloxacin Delafloxacin Butabarbital may decrease the excretion rate of Delafloxacin which could result in a higher serum level.
Tetrabenazine Tetrabenazine The risk or severity of sedation and somnolence can be increased when Butabarbital is combined with Tetrabenazine.
Ertugliflozin Ertugliflozin Ertugliflozin may increase the excretion rate of Butabarbital which could result in a lower serum level and potentially a reduction in efficacy.
Buprenorphine Injection Buprenorphine Injection Butabarbital may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Apalutamide Apalutamide Butabarbital may decrease the excretion rate of Apalutamide which could result in a higher serum level.
Baricitinib Baricitinib Butabarbital may decrease the excretion rate of Baricitinib which could result in a higher serum level.
Lofexidine Lofexidine The therapeutic efficacy of Butabarbital can be increased when used in combination with Lofexidine.
Plazomicin Injection Plazomicin Injection Butabarbital may decrease the excretion rate of Plazomicin which could result in a higher serum level.
Cannabidiol Cannabidiol The risk or severity of adverse effects can be increased when Cannabidiol is combined with Butabarbital.
Stiripentol Stiripentol The risk or severity of adverse effects can be increased when Butabarbital is combined with Stiripentol.
Paclitaxel (with albumin) Injection Paclitaxel (with albumin) Injection Butabarbital may increase the hypotensive activities of Paclitaxel.
Prucalopride Prucalopride Butabarbital may decrease the excretion rate of Prucalopride which could result in a higher serum level.
Magnesium Citrate Magnesium Citrate The therapeutic efficacy of Magnesium citrate can be decreased when used in combination with Butabarbital.
Acyclovir Ophthalmic Acyclovir Ophthalmic Acyclovir may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Brexanolone Injection Brexanolone Injection The risk or severity of adverse effects can be increased when Butabarbital is combined with Brexanolone.
Solriamfetol Solriamfetol The risk or severity of adverse effects can be increased when Butabarbital is combined with Solriamfetol.
Pitolisant Pitolisant Butabarbital may decrease the excretion rate of Pitolisant which could result in a higher serum level.
Phenytoin Injection Phenytoin Injection The risk or severity of adverse effects can be increased when Butabarbital is combined with Phenytoin.
Fosphenytoin Injection Fosphenytoin Injection The risk or severity of adverse effects can be increased when Butabarbital is combined with Fosphenytoin.
Lumateperone Lumateperone The risk or severity of adverse effects can be increased when Butabarbital is combined with Lumateperone.
Lasmiditan Lasmiditan The risk or severity of adverse effects can be increased when Butabarbital is combined with Lasmiditan.
Lemborexant Lemborexant The risk or severity of adverse effects can be increased when Butabarbital is combined with Lemborexant.
Fenfluramine Fenfluramine The risk or severity of adverse effects can be increased when Butabarbital is combined with Fenfluramine.
Progestin-Only (drospirenone) Oral Contraceptives Progestin-Only (drospirenone) Oral Contraceptives Drospirenone may increase the excretion rate of Butabarbital which could result in a lower serum level and potentially a reduction in efficacy.
Viloxazine Viloxazine The risk or severity of adverse effects can be increased when Butabarbital is combined with Viloxazine.
Tobramycin Injection Tobramycin Injection Tobramycin may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Theophylline Theophylline The serum concentration of Theophylline can be decreased when it is combined with Butabarbital.
Fenoprofen Fenoprofen Fenoprofen may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Indomethacin Indomethacin Indomethacin may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Mefenamic Acid Mefenamic Acid Mefenamic acid may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Naproxen Naproxen Naproxen may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Tolmetin Tolmetin Tolmetin may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Sulindac Sulindac Sulindac may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Trazodone Trazodone The risk or severity of adverse effects can be increased when Butabarbital is combined with Trazodone.
Isotretinoin Isotretinoin Butabarbital may decrease the excretion rate of Isotretinoin which could result in a higher serum level.
Sucralfate Sucralfate Butabarbital may decrease the excretion rate of Sucralfate which could result in a higher serum level.
Floxuridine Floxuridine Butabarbital may decrease the excretion rate of Floxuridine which could result in a higher serum level.
Phenobarbital Phenobarbital The risk or severity of adverse effects can be increased when Butabarbital is combined with Phenobarbital.
Metaxalone Metaxalone The risk or severity of adverse effects can be increased when Butabarbital is combined with Metaxalone.
Methotrexate Injection Methotrexate Injection Methotrexate may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Levorphanol Levorphanol The risk or severity of adverse effects can be increased when Butabarbital is combined with Levorphanol.
Primidone Primidone The risk or severity of adverse effects can be increased when Butabarbital is combined with Primidone.
Methsuximide Methsuximide The risk or severity of adverse effects can be increased when Butabarbital is combined with Methsuximide.
Diethylpropion Diethylpropion The risk or severity of adverse effects can be increased when Butabarbital is combined with Diethylpropion.
Chlorpromazine Chlorpromazine Chlorpromazine may increase the hypotensive activities of Butabarbital.
Diazepam Diazepam The risk or severity of adverse effects can be increased when Butabarbital is combined with Diazepam.
Oxazepam Oxazepam The risk or severity of adverse effects can be increased when Butabarbital is combined with Oxazepam.
Flurazepam Flurazepam The risk or severity of adverse effects can be increased when Butabarbital is combined with Flurazepam.
Clorazepate Clorazepate The risk or severity of adverse effects can be increased when Butabarbital is combined with Clorazepic acid.
Lorazepam Lorazepam The risk or severity of adverse effects can be increased when Lorazepam is combined with Butabarbital.
Phenoxybenzamine Phenoxybenzamine Butabarbital may increase the hypotensive activities of Phenoxybenzamine.
Carmustine Carmustine Butabarbital may decrease the excretion rate of Carmustine which could result in a higher serum level.
Amantadine Amantadine Butabarbital may decrease the excretion rate of Amantadine which could result in a higher serum level.
Codeine Codeine The risk or severity of adverse effects can be increased when Butabarbital is combined with Codeine.
Meprobamate Meprobamate The risk or severity of adverse effects can be increased when Butabarbital is combined with Meprobamate.
Chlordiazepoxide Chlordiazepoxide The risk or severity of adverse effects can be increased when Butabarbital is combined with Chlordiazepoxide.
Bromocriptine Bromocriptine The risk or severity of adverse effects can be increased when Butabarbital is combined with Bromocriptine.
Tranylcypromine Tranylcypromine The risk or severity of adverse effects can be increased when Butabarbital is combined with Tranylcypromine.
Phenelzine Phenelzine The risk or severity of adverse effects can be increased when Butabarbital is combined with Phenelzine.
Procarbazine Procarbazine The risk or severity of adverse effects can be increased when Butabarbital is combined with Procarbazine.
Ergoloid Mesylates Ergoloid Mesylates The risk or severity of adverse effects can be increased when Butabarbital is combined with Ergoloid mesylate.
Tetracycline Tetracycline Butabarbital may decrease the excretion rate of Tetracycline which could result in a higher serum level.
Minocycline Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Butabarbital.
Prochlorperazine Prochlorperazine The risk or severity of adverse effects can be increased when Butabarbital is combined with Prochlorperazine.
Thioridazine Thioridazine The risk or severity of adverse effects can be increased when Butabarbital is combined with Thioridazine.
Trifluoperazine Trifluoperazine The risk or severity of adverse effects can be increased when Butabarbital is combined with Trifluoperazine.
Bleomycin Bleomycin Butabarbital may decrease the excretion rate of Bleomycin which could result in a higher serum level.
Sulfadiazine Sulfadiazine Butabarbital may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Oxycodone Oxycodone The risk or severity of adverse effects can be increased when Butabarbital is combined with Oxycodone.
Methadone Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Butabarbital.
Oxybutynin Oxybutynin Butabarbital may increase the central nervous system depressant (CNS depressant) activities of Oxybutynin.
Benztropine Benztropine Butabarbital may increase the central nervous system depressant (CNS depressant) activities of Benzatropine.
Maprotiline Maprotiline Butabarbital may increase the central nervous system depressant (CNS depressant) activities of Maprotiline.
Ibuprofen Ibuprofen Ibuprofen may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Trihexyphenidyl Trihexyphenidyl Butabarbital may increase the central nervous system depressant (CNS depressant) activities of Trihexyphenidyl.
Orphenadrine Orphenadrine Butabarbital may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Perphenazine Perphenazine The risk or severity of adverse effects can be increased when Butabarbital is combined with Perphenazine.
Azathioprine Azathioprine Butabarbital may decrease the excretion rate of Azathioprine which could result in a higher serum level.
Fluphenazine Fluphenazine The risk or severity of adverse effects can be increased when Butabarbital is combined with Fluphenazine.
Methylphenidate Methylphenidate Butabarbital may decrease the excretion rate of Methylphenidate which could result in a higher serum level.
Amoxapine Amoxapine Butabarbital may increase the central nervous system depressant (CNS depressant) activities of Amoxapine.
Sulfasalazine Sulfasalazine Sulfasalazine may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Mechlorethamine Mechlorethamine The therapeutic efficacy of Butabarbital can be decreased when used in combination with Mechlorethamine.
Pyridostigmine Pyridostigmine The therapeutic efficacy of Butabarbital can be decreased when used in combination with Pyridostigmine.
Phenazopyridine Phenazopyridine Phenazopyridine may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Carbamazepine Carbamazepine Butabarbital may decrease the excretion rate of Carbamazepine which could result in a higher serum level.
Molindone Molindone The risk or severity of adverse effects can be increased when Butabarbital is combined with Molindone.
Methyldopa Methyldopa Butabarbital may increase the hypotensive activities of Methyldopa.
Clonidine Clonidine The risk or severity of sedation can be increased when Clonidine is combined with Butabarbital.
Prazosin Prazosin Butabarbital may increase the hypotensive activities of Prazosin.
Hydralazine Hydralazine Butabarbital may increase the hypotensive activities of Hydralazine.
Cimetidine Cimetidine Butabarbital may decrease the excretion rate of Cimetidine which could result in a higher serum level.
Gentamicin Injection Gentamicin Injection Gentamicin may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Warfarin Warfarin Butabarbital may decrease the excretion rate of Warfarin which could result in a higher serum level.
Clonazepam Clonazepam The risk or severity of adverse effects can be increased when Butabarbital is combined with Clonazepam.
Loperamide Loperamide The metabolism of Loperamide can be increased when combined with Butabarbital.
Promethazine Promethazine The risk or severity of adverse effects can be increased when Butabarbital is combined with Promethazine.
Meclofenamate Meclofenamate Meclofenamic acid may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Nitrofurantoin Nitrofurantoin Butabarbital may decrease the excretion rate of Nitrofurantoin which could result in a higher serum level.
Griseofulvin Griseofulvin The serum concentration of Griseofulvin can be decreased when it is combined with Butabarbital.
Digoxin Digoxin Butabarbital may decrease the excretion rate of Digoxin which could result in a higher serum level.
Loxapine Loxapine The risk or severity of adverse effects can be increased when Butabarbital is combined with Loxapine.
Chloroquine Chloroquine Butabarbital may decrease the excretion rate of Chloroquine which could result in a higher serum level.
Quinine Quinine The risk or severity of adverse effects can be increased when Butabarbital is combined with Quinine.
Ethosuximide Ethosuximide The risk or severity of adverse effects can be increased when Butabarbital is combined with Ethosuximide.
Triamterene Triamterene Triamterene may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Lactulose Lactulose The therapeutic efficacy of Lactulose can be decreased when used in combination with Butabarbital.
Chlorothiazide Chlorothiazide Chlorothiazide may increase the excretion rate of Butabarbital which could result in a lower serum level and potentially a reduction in efficacy.
Chlorthalidone Chlorthalidone Chlorthalidone may increase the excretion rate of Butabarbital which could result in a lower serum level and potentially a reduction in efficacy.
Metolazone Metolazone Butabarbital may increase the excretion rate of Metolazone which could result in a lower serum level and potentially a reduction in efficacy.
Isosorbide Isosorbide Isosorbide may increase the excretion rate of Butabarbital which could result in a lower serum level and potentially a reduction in efficacy.
Secobarbital Secobarbital The risk or severity of adverse effects can be increased when Butabarbital is combined with Secobarbital.
Desipramine Desipramine Butabarbital may increase the central nervous system depressant (CNS depressant) activities of Desipramine.
Amitriptyline Amitriptyline Butabarbital may increase the central nervous system depressant (CNS depressant) activities of Amitriptyline.
Imipramine Imipramine Butabarbital may increase the central nervous system depressant (CNS depressant) activities of Imipramine.
Probenecid Probenecid Butabarbital may decrease the excretion rate of Probenecid which could result in a higher serum level.
Quinidine Quinidine Butabarbital may decrease the excretion rate of Quinidine which could result in a higher serum level.
Procainamide Procainamide Procainamide may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Isoniazid Isoniazid Butabarbital may decrease the excretion rate of Isoniazid which could result in a higher serum level.
Pyrazinamide Pyrazinamide Butabarbital may decrease the excretion rate of Pyrazinamide which could result in a higher serum level.
Disopyramide Disopyramide Butabarbital may increase the central nervous system depressant (CNS depressant) activities of Disopyramide.
Valproic Acid Valproic Acid The serum concentration of Valproic acid can be increased when it is combined with Butabarbital.
Liothyronine Liothyronine Butabarbital may decrease the excretion rate of Liothyronine which could result in a higher serum level.
Methimazole Methimazole Butabarbital may decrease the excretion rate of Methimazole which could result in a higher serum level.
Chlorpropamide Chlorpropamide Butabarbital may decrease the excretion rate of Chlorpropamide which could result in a higher serum level.
Tolbutamide Tolbutamide Butabarbital may decrease the excretion rate of Tolbutamide which could result in a higher serum level.
Tolazamide Tolazamide Butabarbital may decrease the excretion rate of Tolazamide which could result in a higher serum level.
Dextromethorphan Dextromethorphan The risk or severity of adverse effects can be increased when Butabarbital is combined with Dextromethorphan.
Cyclobenzaprine Cyclobenzaprine The risk or severity of CNS depression can be increased when Butabarbital is combined with Cyclobenzaprine.
Baclofen Baclofen The risk or severity of adverse effects can be increased when Baclofen is combined with Butabarbital.
Doxylamine Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Butabarbital.
Cyproheptadine Cyproheptadine Butabarbital may increase the central nervous system depressant (CNS depressant) activities of Cyproheptadine.
Clemastine Clemastine The risk or severity of adverse effects can be increased when Butabarbital is combined with Clemastine.
Chlorpheniramine Chlorpheniramine The risk or severity of adverse effects can be increased when Butabarbital is combined with Chlorpheniramine.
Brompheniramine Brompheniramine The risk or severity of adverse effects can be increased when Butabarbital is combined with Dexbrompheniramine.
Meclizine Meclizine The risk or severity of adverse effects can be increased when Butabarbital is combined with Meclizine.
Ethambutol Ethambutol Butabarbital may decrease the excretion rate of Ethambutol which could result in a higher serum level.
Methyclothiazide Methyclothiazide Methyclothiazide may increase the excretion rate of Butabarbital which could result in a lower serum level and potentially a reduction in efficacy.
Hydrochlorothiazide Hydrochlorothiazide Hydrochlorothiazide may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Dantrolene Dantrolene The risk or severity of adverse effects can be increased when Butabarbital is combined with Dantrolene.
Chlorzoxazone Chlorzoxazone The risk or severity of adverse effects can be increased when Butabarbital is combined with Chlorzoxazone.
Carisoprodol Carisoprodol The risk or severity of adverse effects can be increased when Carisoprodol is combined with Butabarbital.
Methocarbamol Methocarbamol The risk or severity of adverse effects can be increased when Butabarbital is combined with Methocarbamol.
Pyridoxine Pyridoxine The metabolism of Butabarbital can be increased when combined with Pyridoxine.
Folic Acid Folic Acid Folic acid may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) Butabarbital may increase the hypotensive activities of Propranolol.
Minoxidil Minoxidil Butabarbital may increase the hypotensive activities of Minoxidil.
Nortriptyline Nortriptyline Butabarbital may increase the central nervous system depressant (CNS depressant) activities of Nortriptyline.
Spironolactone Spironolactone Spironolactone may increase the excretion rate of Butabarbital which could result in a lower serum level and potentially a reduction in efficacy.
Amphotericin B Injection Amphotericin B Injection Amphotericin B may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Mercaptopurine Mercaptopurine The serum concentration of Mercaptopurine can be decreased when it is combined with Butabarbital.
Phytonadione Phytonadione Butabarbital may decrease the excretion rate of Phylloquinone which could result in a higher serum level.
Amikacin Injection Amikacin Injection Amikacin may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Nadolol Nadolol Butabarbital may increase the hypotensive activities of Nadolol.
Butorphanol Injection Butorphanol Injection The risk or severity of adverse effects can be increased when Butabarbital is combined with Butorphanol.
Nalbuphine Injection Nalbuphine Injection The risk or severity of adverse effects can be increased when Butabarbital is combined with Nalbuphine.
Allopurinol Allopurinol Butabarbital may decrease the excretion rate of Allopurinol which could result in a higher serum level.
Trimethobenzamide Trimethobenzamide The risk or severity of adverse effects can be increased when Butabarbital is combined with Trimethobenzamide.
Flavoxate Flavoxate Butabarbital may increase the central nervous system depressant (CNS depressant) activities of Flavoxate.
Papaverine Papaverine Butabarbital may increase the hypotensive activities of Papaverine.
Colchicine Colchicine Butabarbital may decrease the excretion rate of Colchicine which could result in a higher serum level.
Cefaclor Cefaclor Cefaclor may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Cefadroxil Cefadroxil Cefadroxil may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Cefazolin Injection Cefazolin Injection Cefazolin may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Cephalexin Cephalexin Cephalexin may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Cefoxitin Injection Cefoxitin Injection Cefoxitin may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Dacarbazine Dacarbazine Butabarbital may decrease the excretion rate of Dacarbazine which could result in a higher serum level.
Acetazolamide Acetazolamide The risk or severity of adverse effects can be increased when Butabarbital is combined with Acetazolamide.
Cefotaxime Injection Cefotaxime Injection Cefotaxime may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Calcitonin Salmon Injection Calcitonin Salmon Injection Salmon calcitonin may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Pyrantel Pyrantel The risk or severity of adverse effects can be increased when Butabarbital is combined with Pyrantel.
Thiotepa Injection Thiotepa Injection The therapeutic efficacy of Butabarbital can be decreased when used in combination with Thiotepa.
Captopril Captopril Butabarbital may increase the hypotensive activities of Captopril.
Dipyridamole Dipyridamole Butabarbital may increase the hypotensive activities of Dipyridamole.
Isoxsuprine Isoxsuprine Butabarbital may increase the hypotensive activities of Isoxsuprine.
Ethacrynic Acid Ethacrynic Acid Etacrynic acid may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Colistimethate Injection Colistimethate Injection Colistimethate may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Metoprolol Metoprolol Butabarbital may increase the hypotensive activities of Metoprolol.
Hydroxyzine Hydroxyzine Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Butabarbital.
Thiothixene Thiothixene The risk or severity of adverse effects can be increased when Butabarbital is combined with Thiothixene.
Aspirin Aspirin Acetylsalicylic acid may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Salsalate Salsalate Salsalate may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Alprazolam Alprazolam The risk or severity of adverse effects can be increased when Butabarbital is combined with Alprazolam.
Temazepam Temazepam The risk or severity of adverse effects can be increased when Temazepam is combined with Butabarbital.
Triazolam Triazolam The risk or severity of adverse effects can be increased when Butabarbital is combined with Triazolam.
Dicyclomine Dicyclomine Butabarbital may increase the central nervous system depressant (CNS depressant) activities of Dicyclomine.
Hyoscyamine Hyoscyamine Butabarbital may increase the central nervous system depressant (CNS depressant) activities of Hyoscyamine.
Propantheline Propantheline Butabarbital may increase the central nervous system depressant (CNS depressant) activities of Propantheline.
Trimethoprim Trimethoprim Butabarbital may decrease the excretion rate of Trimethoprim which could result in a higher serum level.
Diltiazem Diltiazem Butabarbital may increase the hypotensive activities of Diltiazem.
Nifedipine Nifedipine Butabarbital may increase the hypotensive activities of Nifedipine.
Timolol Timolol Butabarbital may increase the hypotensive activities of Timolol.
Verapamil Verapamil Butabarbital may increase the hypotensive activities of Verapamil.
Atenolol Atenolol Butabarbital may increase the hypotensive activities of Atenolol.
Pindolol Pindolol The risk or severity of adverse effects can be increased when Butabarbital is combined with Pindolol.
Cisplatin Injection Cisplatin Injection Cisplatin may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Diflunisal Diflunisal Diflunisal may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Piroxicam Piroxicam Piroxicam may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Bumetanide Bumetanide Butabarbital may increase the excretion rate of Bumetanide which could result in a lower serum level and potentially a reduction in efficacy.
Glipizide Glipizide Butabarbital may decrease the excretion rate of Glipizide which could result in a higher serum level.
Indapamide Indapamide Butabarbital may increase the excretion rate of Indapamide which could result in a lower serum level and potentially a reduction in efficacy.
Amoxicillin Amoxicillin Butabarbital may decrease the excretion rate of Amoxicillin which could result in a higher serum level.
Oxacillin Injection Oxacillin Injection Butabarbital may decrease the excretion rate of Oxacillin which could result in a higher serum level.
Pentoxifylline Pentoxifylline The serum concentration of Pentoxifylline can be decreased when it is combined with Butabarbital.
Pentamidine Injection Pentamidine Injection Pentamidine may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Ceftriaxone Injection Ceftriaxone Injection Ceftriaxone may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Labetalol Labetalol Butabarbital may increase the hypotensive activities of Labetalol.
Auranofin Auranofin Butabarbital may decrease the excretion rate of Auranofin which could result in a higher serum level.
Leuprolide Injection Leuprolide Injection Leuprolide may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Gemfibrozil Gemfibrozil Butabarbital may decrease the excretion rate of Gemfibrozil which could result in a higher serum level.
Dipivefrin Ophthalmic Dipivefrin Ophthalmic Adefovir dipivoxil may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Ceftazidime Injection Ceftazidime Injection Ceftazidime may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Ketoprofen Ketoprofen Ketoprofen may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Cefotetan Injection Cefotetan Injection Cefotetan may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Pimozide Pimozide The risk or severity of adverse effects can be increased when Butabarbital is combined with Pimozide.
Enalapril Enalapril Butabarbital may increase the hypotensive activities of Enalapril.
Flurbiprofen Flurbiprofen Flurbiprofen may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Amiodarone Amiodarone Butabarbital may increase the hypotensive activities of Amiodarone.
Aztreonam Injection Aztreonam Injection Butabarbital may decrease the excretion rate of Aztreonam which could result in a higher serum level.
Buspirone Buspirone Butabarbital may decrease the excretion rate of Buspirone which could result in a higher serum level.
Ciprofloxacin Ciprofloxacin Butabarbital may decrease the excretion rate of Ciprofloxacin which could result in a higher serum level.
Mesalamine Mesalamine Mesalazine may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Diclofenac Diclofenac Diclofenac may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Fluoxetine Fluoxetine Butabarbital may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Nimodipine Nimodipine Butabarbital may increase the hypotensive activities of Nimodipine.
Clozapine Clozapine The risk or severity of adverse effects can be increased when Butabarbital is combined with Clozapine.
Estazolam Estazolam The risk or severity of adverse effects can be increased when Butabarbital is combined with Estazolam.
Didanosine Didanosine Butabarbital may decrease the excretion rate of Didanosine which could result in a higher serum level.
Pentostatin Injection Pentostatin Injection Butabarbital may decrease the excretion rate of Pentostatin which could result in a higher serum level.
Benazepril Benazepril Butabarbital may increase the hypotensive activities of Benazepril.
Etodolac Etodolac Etodolac may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Felodipine Felodipine Butabarbital may increase the hypotensive activities of Felodipine.
Fosinopril Fosinopril Butabarbital may increase the hypotensive activities of Fosinopril.
Nabumetone Nabumetone Nabumetone may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Quinapril Quinapril Butabarbital may increase the hypotensive activities of Quinapril.
Ramipril Ramipril Ramipril may increase the hypotensive activities of Butabarbital.
Amlodipine Amlodipine Butabarbital may increase the hypotensive activities of Amlodipine.
Teniposide Injection Teniposide Injection The serum concentration of Teniposide can be decreased when it is combined with Butabarbital.
Lisinopril Lisinopril Butabarbital may increase the hypotensive activities of Lisinopril.
Oxaprozin Oxaprozin Oxaprozin may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Sotalol Sotalol Butabarbital may increase the hypotensive activities of Sotalol.
Bisoprolol Bisoprolol Butabarbital may increase the hypotensive activities of Bisoprolol.
Zolpidem Zolpidem Butabarbital may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Doxazosin Doxazosin Butabarbital may increase the hypotensive activities of Doxazosin.
Terazosin Terazosin Butabarbital may increase the hypotensive activities of Terazosin.
Isradipine Isradipine Butabarbital may increase the hypotensive activities of Isradipine.
Cisapride Cisapride The risk or severity of adverse effects can be increased when Butabarbital is combined with Cisapride.
Gabapentin Gabapentin The risk or severity of adverse effects can be increased when Butabarbital is combined with Gabapentin.
Venlafaxine Venlafaxine The risk or severity of adverse effects can be increased when Butabarbital is combined with Venlafaxine.
Nizatidine Nizatidine The therapeutic efficacy of Butabarbital can be decreased when used in combination with Nizatidine.
Fluvoxamine Fluvoxamine The risk or severity of adverse effects can be increased when Butabarbital is combined with Fluvoxamine.
Nefazodone Nefazodone The risk or severity of adverse effects can be increased when Butabarbital is combined with Nefazodone.
Lamotrigine Lamotrigine The serum concentration of Lamotrigine can be decreased when it is combined with Butabarbital.
Losartan Losartan Butabarbital may increase the hypotensive activities of Losartan.
Valacyclovir Valacyclovir Valaciclovir may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Tramadol Tramadol The risk or severity of CNS depression can be increased when Butabarbital is combined with Tramadol.
Carboplatin Injection Carboplatin Injection Carboplatin may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Moexipril Moexipril Butabarbital may increase the hypotensive activities of Moexipril.
Ifosfamide Injection Ifosfamide Injection Butabarbital may decrease the excretion rate of Ifosfamide which could result in a higher serum level.
Nicardipine Nicardipine Butabarbital may increase the central nervous system depressant (CNS depressant) activities of Nicardipine.
Bupropion Bupropion The risk or severity of adverse effects can be increased when Butabarbital is combined with Bupropion.
Ticlopidine Ticlopidine Ticlopidine may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Metformin Metformin Butabarbital may decrease the excretion rate of Metformin which could result in a higher serum level.
Nisoldipine Nisoldipine Butabarbital may increase the hypotensive activities of Nisoldipine.
Lamivudine Lamivudine Butabarbital may decrease the excretion rate of Lamivudine which could result in a higher serum level.
Riluzole Riluzole The risk or severity of adverse effects can be increased when Butabarbital is combined with Riluzole.
Amifostine Injection Amifostine Injection Butabarbital may increase the hypotensive activities of Amifostine.
Acarbose Acarbose Butabarbital may decrease the excretion rate of Acarbose which could result in a higher serum level.
Gemcitabine Injection Gemcitabine Injection Butabarbital may decrease the excretion rate of Gemcitabine which could result in a higher serum level.
Cidofovir Injection Cidofovir Injection Cidofovir may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Meropenem Injection Meropenem Injection Butabarbital may decrease the excretion rate of Meropenem which could result in a higher serum level.
Clomipramine Clomipramine The risk or severity of adverse effects can be increased when Butabarbital is combined with Clomipramine.
Fosfomycin Fosfomycin Butabarbital may decrease the excretion rate of Fosfomycin which could result in a higher serum level.
Mirtazapine Mirtazapine Butabarbital may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Trandolapril Trandolapril Butabarbital may increase the hypotensive activities of Trandolapril.
Topiramate Topiramate The risk or severity of adverse effects can be increased when Butabarbital is combined with Topiramate.
Valsartan Valsartan Butabarbital may increase the hypotensive activities of Valsartan.
Pramipexole Pramipexole Butabarbital may increase the sedative activities of Pramipexole.
Donepezil Donepezil The therapeutic efficacy of Butabarbital can be decreased when used in combination with Donepezil.
Loratadine Loratadine Butabarbital may increase the anticholinergic activities of Loratadine.
Carvedilol Carvedilol Butabarbital may increase the hypotensive activities of Carvedilol.
Nilutamide Nilutamide Butabarbital may decrease the excretion rate of Nilutamide which could result in a higher serum level.
Flutamide Flutamide Butabarbital may decrease the excretion rate of Flutamide which could result in a higher serum level.
Selegiline Selegiline The risk or severity of adverse effects can be increased when Butabarbital is combined with Selegiline.
Sertraline Sertraline The risk or severity of adverse effects can be increased when Butabarbital is combined with Sertraline.
Propafenone Propafenone The serum concentration of Propafenone can be decreased when it is combined with Butabarbital.
Irbesartan Irbesartan Butabarbital may increase the hypotensive activities of Irbesartan.
Tamsulosin Tamsulosin Butabarbital may increase the hypotensive activities of Tamsulosin.
Ropinirole Ropinirole Butabarbital may increase the sedative activities of Ropinirole.
Quetiapine Quetiapine The risk or severity of adverse effects can be increased when Butabarbital is combined with Quetiapine.
Cefepime Injection Cefepime Injection Cefepime may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Cefprozil Cefprozil Cefprozil may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Cefpodoxime Cefpodoxime Cefpodoxime may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Cetirizine Cetirizine The risk or severity of adverse effects can be increased when Butabarbital is combined with Cetirizine.
Paroxetine Paroxetine The risk or severity of adverse effects can be increased when Butabarbital is combined with Paroxetine.
Tolcapone Tolcapone The risk or severity of adverse effects can be increased when Butabarbital is combined with Tolcapone.
Citalopram Citalopram The risk or severity of adverse effects can be increased when Butabarbital is combined with Citalopram.
Capecitabine Capecitabine Butabarbital may decrease the excretion rate of Capecitabine which could result in a higher serum level.
Efavirenz Efavirenz The risk or severity of adverse effects can be increased when Butabarbital is combined with Efavirenz.
Abacavir Abacavir Butabarbital may decrease the excretion rate of Abacavir which could result in a higher serum level.
Celecoxib Celecoxib Celecoxib may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Rosiglitazone Rosiglitazone Butabarbital may decrease the excretion rate of Rosiglitazone which could result in a higher serum level.
Tolterodine Tolterodine Butabarbital may increase the central nervous system depressant (CNS depressant) activities of Tolterodine.
Thalidomide Thalidomide Butabarbital may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Oseltamivir Oseltamivir Oseltamivir may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Balsalazide Balsalazide Balsalazide may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Nateglinide Nateglinide Butabarbital may decrease the excretion rate of Nateglinide which could result in a higher serum level.
Galantamine Galantamine The therapeutic efficacy of Butabarbital can be decreased when used in combination with Galantamine.
Levetiracetam Levetiracetam The risk or severity of adverse effects can be increased when Butabarbital is combined with Levetiracetam.
Rabeprazole Rabeprazole Butabarbital may decrease the excretion rate of Rabeprazole which could result in a higher serum level.

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