Fluvastatin

Generic name: Pronounced as (floo' va sta tin)
Brand names
  • Lescol®
  • Lescol® XL
Click on drug name to hear pronunciation

Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 11/15/2017

[Posted 07/20/2021]

AUDIENCE: Patient, Health Professional, OBGYN, Cardiology, Endocrinology, Pharmacy

ISSUE: The FDA is requesting revisions to the information about use in pregnancy in the prescribing information of the entire class of statin medicines. These changes include removing the contraindication against using these medicines in all pregnant patients. A contraindication is FDA's strongest warning and is only added when a medicine should not be used because the risk clearly outweighs any possible benefit. Because the benefits of statins may include prevention of serious or potentially fatal events in a small group of very high-risk pregnant patients, contraindicating these drugs in all pregnant women is not appropriate.

FDA expects removing the contraindication will enable health care professionals and patients to make individual decisions about benefit and risk, especially for those at very high risk of heart attack or stroke. This includes patients with homozygous familial hypercholesterolemia and those who have previously had a heart attack or stroke.

BACKGROUND: Statins are a class of prescription medicines that have been used for decades to lower low-density lipoprotein (LDL-C or "bad") cholesterol in the blood. Medicines in the statin class include atorvastatin, fluvastatin, lovastatin, pitavastatin, pravastatin, rosuvastatin, and simvastatin.

RECOMMENDATIONS:

  • Patients: Patients taking statins should notify their health care professionals if they become pregnant or suspect they are pregnant. Your health care professional will be able to advise whether you should stop taking the medicine during pregnancy and whether you may stop your statin temporarily while breastfeeding. Patients who are at high risk of heart attack or stroke who require statins after giving birth should not breastfeed and should use alternatives such as infant formula.

  • Health Care Professionals: Health care professionals should discontinue statin therapy in most pregnant patients, or they can consider the ongoing therapeutic needs of the individual patient, particularly those at very high risk for cardiovascular events during pregnancy. Because of the chronic nature of cardiovascular disease, treatment of hyperlipidemia is not generally necessary during pregnancy. Discuss with patients whether they may discontinue statins temporarily while breastfeeding. Advise those who require a statin because of their cardiovascular risk that breastfeeding is not recommended because the medicine may pass into breast milk

The FDA hopes the revised language in the prescribing information will help reassure health care professionals that statins are safe to prescribe in patients who can become pregnant, and help them reassure patients with unintended statin exposure in early pregnancy or before pregnancy is recognized that the medicine is unlikely to harm the unborn baby.

For more information visit the FDA website at: http://www.fda.gov/Safety/MedWatch/SafetyInformation and http://www.fda.gov/Drugs/DrugSafety.

Fluvastatin is used together with diet, weight loss, and exercise to reduce the risk of heart attack and stroke and to decrease the chance that heart surgery will be needed in people who have heart disease or who are at risk of developing heart disease. Fluvastatin is also used to decrease the amount of fatty substances such as low-density lipoprotein (LDL) cholesterol ('bad cholesterol') and triglycerides in the blood and to increase the amount of high-density lipoprotein (HDL) cholesterol ('good cholesterol') in the blood. Fluvastatin may also be used to decrease the amount of cholesterol and other fatty substances in the blood in children and teenagers 10 to 17 years of age who have familial heterozygous hypercholesterolemia (an inherited condition in which cholesterol cannot be removed from the body normally). Fluvastatin is in a class of medications called HMG-CoA reductase inhibitors (statins). It works by slowing the production of cholesterol in the body to decrease the amount of cholesterol that may build up on the walls of the arteries and block blood flow to the heart, brain, and other parts of the body.

Accumulation of cholesterol and fats along the walls of your arteries (a process known as atherosclerosis) decreases blood flow and, therefore, the oxygen supply to your heart, brain, and other parts of your body. Lowering your blood level of cholesterol and fats with fluvastatin has been shown to prevent heart disease, angina (chest pain), strokes, and heart attacks.

Fluvastatin comes as a capsule and an extended-release (long-acting) tablet to take by mouth. The capsule is usually taken with or without food once a day at bedtime or twice a day. The extended-release tablet is usually taken once a day with or without food. Take fluvastatin at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take fluvastatin exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Swallow the extended-release tablets whole; do not split, chew, or crush them.

Your doctor may start you on a low dose of fluvastatin and gradually increase your dose, not more than once every 4 weeks.

Continue to take fluvastatin even if you feel well. Do not stop taking fluvastatin without talking to your doctor.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking fluvastatin,

  • tell your doctor and pharmacist if you are allergic to fluvastatin, any other medications, or any of the ingredients in fluvastatin capsules or extended release tablets. Ask your pharmacist for a list of the ingredients..

  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: anticoagulants ('blood thinners') such as warfarin; cimetidine (Tagamet); colchicine (Colcrys); cyclosporine (Neoral, Sandimmune); diclofenac (Cataflam, Voltaren); digoxin (Lanoxin); erythromycin (E.E.S., E-Mycin, Erythrocin); fluconazole (Diflucan), glyburide (DiaBeta, Glynase, Micronase); ketoconazole (Nizoral); omeprazole (Prilosec); other cholesterol-lowering medications such as cholestyramine (Questran), fenofibrate (Tricor), gemfibrozil (Lopid), and niacin (nicotinic acid, Niacor, Niaspan); phenytoin (Dilantin); ranitidine (Zantac); rifampin (Rifadin, Rimactane); and spironolactone (Aldactone). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with fluvastatin, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.

  • tell your doctor if you have liver disease. Your doctor will order laboratory tests to see how well your liver is working even if you do not think you have liver disease.Your doctor will probably tell you not to take fluvastatin if you have liver disease or if the tests show that you may be developing liver disease.

  • tell your doctor if you drink more than 2 alcoholic beverages per day, if you are 65 years of age or older, and if you have ever had liver disease or have or ever had muscle aches or weakness, diabetes, low blood pressure, seizures, or thyroid or kidney disease.

  • tell your doctor if you are pregnant, or plan to become pregnant. You should not become pregnant while you are taking fluvastatin. Talk to your doctor about birth control methods that you can use during your treatment. If you become pregnant while taking fluvastatin, stop taking fluvastatin and call your doctor immediately. Fluvastatin may harm the fetus.

  • do not breast-feed while you are taking this medication.

  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking fluvastatin. If you are hospitalized due to infection or serious injury, tell the doctor who treats you that you are taking fluvastatin.

  • ask your doctor about the safe use of alcoholic beverages while you are taking fluvastatin. Alcohol can increase the risk of serious side effects.

Eat a low-fat, low-cholesterol diet. Be sure to follow all exercise and dietary recommendations made by your doctor or dietitian. You can also visit the National Cholesterol Education Program (NCEP) website for additional dietary information at http://www.nhlbi.nih.gov/health/public/heart/chol/chol_tlc.pdf.

Take the missed dose as soon as you remember it. However, if it has been more than 12 hours since your last dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

  • Fluvastatin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • headache

    • heartburn

    • difficulty falling asleep or staying asleep

    • sinus pain

    • cough

    • memory loss or forgetfulness

    • confusion

  • Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately or get emergency medical help :

    • muscle pain, tenderness, or weakness

    • lack of energy

    • fever

    • yellowing of the skin or eyes

    • pain in the upper right part of the stomach

    • dark colored urine

    • nausea

    • extreme tiredness

    • unusual bleeding or bruising

    • loss of appetite

    • flu-like symptoms

    • rash

    • hives

    • itching

    • difficulty breathing or swallowing

    • swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs

    • hoarseness

  • Fluvastatin may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Keep all appointments with your doctor and the laboratory. Your doctor may order laboratory tests during your treatment, especially if you develop symptoms of liver damage.

Before having any laboratory test, tell your doctor and the laboratory personnel that you are taking fluvastatin.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug Interaction
Repaglinide Repaglinide The metabolism of Repaglinide can be decreased when combined with Fluvastatin.
Montelukast Montelukast The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Montelukast is combined with Fluvastatin.
Leflunomide Leflunomide The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Fluvastatin is combined with Leflunomide.
Delavirdine Delavirdine The metabolism of Fluvastatin can be decreased when combined with Delavirdine.
Nevirapine Nevirapine The metabolism of Fluvastatin can be decreased when combined with Nevirapine.
Atorvastatin Atorvastatin The metabolism of Atorvastatin can be decreased when combined with Fluvastatin.
Dolasetron Dolasetron The metabolism of Fluvastatin can be decreased when combined with Dolasetron.
Alendronate Alendronate The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Alendronic acid is combined with Fluvastatin.
Aminophylline Aminophylline The metabolism of Aminophylline can be decreased when combined with Fluvastatin.
Candesartan Candesartan The metabolism of Fluvastatin can be decreased when combined with Candesartan.
Cilostazol Cilostazol The serum concentration of Cilostazol can be increased when it is combined with Fluvastatin.
Clopidogrel Clopidogrel The metabolism of Fluvastatin can be decreased when combined with Clopidogrel.
Erythromycin and Sulfisoxazole Erythromycin and Sulfisoxazole The metabolism of Fluvastatin can be decreased when combined with Erythromycin.
Estrogen and Progestin (Oral Contraceptives) Estrogen and Progestin (Oral Contraceptives) The excretion of Conjugated estrogens can be decreased when combined with Fluvastatin.
Fenofibrate Fenofibrate The risk or severity of myopathy and rhabdomyolysis can be increased when Fenofibrate is combined with Fluvastatin.
Nafarelin Nafarelin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Nafarelin is combined with Fluvastatin.
Paregoric Paregoric The metabolism of Morphine can be decreased when combined with Fluvastatin.
Penbutolol Penbutolol The metabolism of Fluvastatin can be decreased when combined with Acebutolol.
Ranitidine Ranitidine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ranitidine is combined with Fluvastatin.
Reserpine Reserpine The metabolism of Fluvastatin can be increased when combined with Reserpine.
Sumatriptan Sumatriptan The excretion of Sumatriptan can be decreased when combined with Fluvastatin.
Tacrolimus Tacrolimus The serum concentration of Tacrolimus can be increased when it is combined with Fluvastatin.
Triamcinolone Triamcinolone The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Triamcinolone is combined with Fluvastatin.
Fluconazole Injection Fluconazole Injection The metabolism of Fluvastatin can be decreased when combined with Fluconazole.
Hydromorphone Injection Hydromorphone Injection The metabolism of Hydromorphone can be decreased when combined with Fluvastatin.
Meperidine Injection Meperidine Injection The metabolism of Meperidine can be decreased when combined with Fluvastatin.
Metoclopramide Injection Metoclopramide Injection The metabolism of Fluvastatin can be decreased when combined with Metoclopramide.
Metronidazole Injection Metronidazole Injection The metabolism of Fluvastatin can be decreased when combined with Metronidazole.
Morphine Injection Morphine Injection The metabolism of Morphine can be decreased when combined with Fluvastatin.
Pamidronate Injection Pamidronate Injection The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Pamidronic acid is combined with Fluvastatin.
Zidovudine Injection Zidovudine Injection The metabolism of Fluvastatin can be increased when combined with Zidovudine.
Altretamine Altretamine The metabolism of Fluvastatin can be decreased when combined with Amphetamine.
Cyclosporine Cyclosporine The serum concentration of Fluvastatin can be increased when it is combined with Cyclosporine.
Ondansetron Ondansetron The metabolism of Ondansetron can be decreased when combined with Fluvastatin.
Torsemide Torsemide The metabolism of Torasemide can be decreased when combined with Fluvastatin.
Olanzapine Olanzapine The metabolism of Fluvastatin can be decreased when combined with Olanzapine.
Alosetron Alosetron The metabolism of Alosetron can be decreased when combined with Fluvastatin.
Dofetilide Dofetilide The metabolism of Dofetilide can be decreased when combined with Fluvastatin.
Entacapone Entacapone The metabolism of Fluvastatin can be decreased when combined with Entacapone.
Eprosartan Eprosartan The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Eprosartan is combined with Fluvastatin.
Hydroxychloroquine Hydroxychloroquine The metabolism of Fluvastatin can be decreased when combined with Hydroxychloroquine.
Meloxicam Meloxicam The metabolism of Meloxicam can be decreased when combined with Fluvastatin.
Oxcarbazepine Oxcarbazepine The metabolism of Fluvastatin can be increased when combined with Oxcarbazepine.
Pantoprazole Pantoprazole The metabolism of Pantoprazole can be decreased when combined with Fluvastatin.
Risedronate Risedronate The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Risedronic acid is combined with Fluvastatin.
Sevelamer Sevelamer Sevelamer can cause a decrease in the absorption of Fluvastatin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Zaleplon Zaleplon The metabolism of Fluvastatin can be decreased when combined with Zaleplon.
Anakinra Anakinra The metabolism of Fluvastatin can be increased when combined with Anakinra.
Trimipramine Trimipramine The metabolism of Trimipramine can be decreased when combined with Fluvastatin.
Etanercept Injection Etanercept Injection The metabolism of Fluvastatin can be increased when combined with Etanercept.
Modafinil Modafinil The metabolism of Fluvastatin can be increased when combined with Modafinil.
Tenofovir Tenofovir The metabolism of Tenofovir can be decreased when combined with Fluvastatin.
Sirolimus Sirolimus The metabolism of Sirolimus can be decreased when combined with Fluvastatin.
Dutasteride Dutasteride The metabolism of Dutasteride can be decreased when combined with Fluvastatin.
Epinephrine Injection Epinephrine Injection The metabolism of Fluvastatin can be decreased when combined with Epinephrine.
Eplerenone Eplerenone The metabolism of Fluvastatin can be decreased when combined with Eplerenone.
Escitalopram Escitalopram The serum concentration of Escitalopram can be increased when it is combined with Fluvastatin.
Zonisamide Zonisamide The metabolism of Zonisamide can be decreased when combined with Fluvastatin.
Adalimumab Injection Adalimumab Injection The metabolism of Fluvastatin can be increased when combined with Adalimumab.
Aripiprazole Aripiprazole The metabolism of Aripiprazole can be decreased when combined with Fluvastatin.
Atomoxetine Atomoxetine The metabolism of Fluvastatin can be decreased when combined with Atomoxetine.
Ezetimibe Ezetimibe The excretion of Ezetimibe can be decreased when combined with Fluvastatin.
Atazanavir Atazanavir The metabolism of Fluvastatin can be decreased when combined with Atazanavir.
Almotriptan Almotriptan The metabolism of Almotriptan can be decreased when combined with Fluvastatin.
Eletriptan Eletriptan The metabolism of Eletriptan can be decreased when combined with Fluvastatin.
Mefloquine Mefloquine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Mefloquine is combined with Fluvastatin.
Rosuvastatin Rosuvastatin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Fluvastatin is combined with Rosuvastatin.
Vardenafil Vardenafil The metabolism of Vardenafil can be decreased when combined with Fluvastatin.
Alfuzosin Alfuzosin The metabolism of Alfuzosin can be decreased when combined with Fluvastatin.
Aprepitant Aprepitant The metabolism of Fluvastatin can be decreased when combined with Aprepitant.
Tegaserod Tegaserod The metabolism of Fluvastatin can be decreased when combined with Tegaserod.
Tadalafil Tadalafil The metabolism of Fluvastatin can be decreased when combined with Tadalafil.
Progesterone Progesterone The metabolism of Progesterone can be decreased when combined with Fluvastatin.
Apomorphine Injection Apomorphine Injection The metabolism of Apomorphine can be decreased when combined with Fluvastatin.
Infliximab Injection Infliximab Injection The metabolism of Fluvastatin can be increased when combined with Infliximab.
Oxandrolone Oxandrolone The metabolism of Fluvastatin can be decreased when combined with Oxandrolone.
Protriptyline Protriptyline The metabolism of Fluvastatin can be decreased when combined with Protriptyline.
Rifaximin Rifaximin The metabolism of Fluvastatin can be increased when combined with Rifaximin.
Duloxetine Duloxetine The metabolism of Duloxetine can be decreased when combined with Fluvastatin.
Norethindrone Norethindrone The metabolism of Norethisterone can be decreased when combined with Fluvastatin.
Trospium Trospium The metabolism of Fluvastatin can be decreased when combined with Trospium.
Bosentan Bosentan The serum concentration of Fluvastatin can be decreased when it is combined with Bosentan.
Cinacalcet Cinacalcet The metabolism of Fluvastatin can be decreased when combined with Cinacalcet.
Erlotinib Erlotinib The metabolism of Fluvastatin can be decreased when combined with Erlotinib.
Eszopiclone Eszopiclone The metabolism of Eszopiclone can be decreased when combined with Fluvastatin.
Ganciclovir Ganciclovir The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ganciclovir is combined with Fluvastatin.
Solifenacin Solifenacin The metabolism of Solifenacin can be decreased when combined with Fluvastatin.
Voriconazole Voriconazole The metabolism of Fluvastatin can be decreased when combined with Voriconazole.
Dextroamphetamine Dextroamphetamine The metabolism of Fluvastatin can be decreased when combined with Amphetamine.
Peginterferon Alfa-2b (PEG-Intron) Peginterferon Alfa-2b (PEG-Intron) The metabolism of Fluvastatin can be increased when combined with Peginterferon alfa-2b.
Ibandronate Ibandronate The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ibandronate is combined with Fluvastatin.
Ramelteon Ramelteon The metabolism of Ramelteon can be decreased when combined with Fluvastatin.
Darifenacin Darifenacin The metabolism of Darifenacin can be decreased when combined with Fluvastatin.
Fentanyl Fentanyl The metabolism of Fentanyl can be decreased when combined with Fluvastatin.
Deferasirox Deferasirox The metabolism of Fluvastatin can be decreased when combined with Deferasirox.
Tipranavir Tipranavir The metabolism of Tipranavir can be decreased when combined with Fluvastatin.
Felbamate Felbamate The metabolism of Fluvastatin can be decreased when combined with Felbamate.
Ranolazine Ranolazine The serum concentration of Fluvastatin can be increased when it is combined with Ranolazine.
Abatacept Injection Abatacept Injection The metabolism of Fluvastatin can be increased when combined with Abatacept.
Imatinib Imatinib The metabolism of Fluvastatin can be decreased when combined with Imatinib.
Sitagliptin Sitagliptin The metabolism of Sitagliptin can be decreased when combined with Fluvastatin.
Gefitinib Gefitinib The metabolism of Fluvastatin can be decreased when combined with Gefitinib.
Paliperidone Paliperidone The metabolism of Paliperidone can be decreased when combined with Fluvastatin.
Bortezomib Bortezomib The metabolism of Fluvastatin can be decreased when combined with Bortezomib.
Primaquine Primaquine The metabolism of Primaquine can be decreased when combined with Fluvastatin.
Darunavir Darunavir The excretion of Fluvastatin can be decreased when combined with Darunavir.
Lisdexamfetamine Lisdexamfetamine The metabolism of Fluvastatin can be decreased when combined with Lisdexamfetamine.
Nabilone Nabilone The metabolism of Fluvastatin can be decreased when combined with Nabilone.
Retapamulin Retapamulin The metabolism of Retapamulin can be decreased when combined with Fluvastatin.
Sorafenib Sorafenib The metabolism of Fluvastatin can be decreased when combined with Sorafenib.
Sunitinib Sunitinib The metabolism of Sunitinib can be decreased when combined with Fluvastatin.
Dronabinol Dronabinol The metabolism of Dronabinol can be decreased when combined with Fluvastatin.
Lapatinib Lapatinib The metabolism of Lapatinib can be decreased when combined with Fluvastatin.
Dasatinib Dasatinib The metabolism of Dasatinib can be decreased when combined with Fluvastatin.
Mexiletine Mexiletine The metabolism of Mexiletine can be increased when combined with Fluvastatin.
Armodafinil Armodafinil The metabolism of Fluvastatin can be increased when combined with Armodafinil.
Ivermectin Ivermectin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ivermectin is combined with Fluvastatin.
Temsirolimus Temsirolimus The metabolism of Temsirolimus can be decreased when combined with Fluvastatin.
Nilotinib Nilotinib The metabolism of Fluvastatin can be decreased when combined with Nilotinib.
Raltegravir Raltegravir The risk or severity of myopathy and rhabdomyolysis can be increased when Raltegravir is combined with Fluvastatin.
Bexarotene Bexarotene The metabolism of Fluvastatin can be decreased when combined with Bexarotene.
Budesonide Budesonide The metabolism of Fluvastatin can be increased when combined with Budesonide.
Chloramphenicol Injection Chloramphenicol Injection The metabolism of Fluvastatin can be decreased when combined with Chloramphenicol.
Etravirine Etravirine The serum concentration of Fluvastatin can be increased when it is combined with Etravirine.
Desvenlafaxine Desvenlafaxine The metabolism of Fluvastatin can be decreased when combined with Desvenlafaxine.
Cevimeline Cevimeline The metabolism of Fluvastatin can be decreased when combined with Cevimeline.
Nebivolol Nebivolol The metabolism of Nebivolol can be decreased when combined with Fluvastatin.
Tretinoin Tretinoin The metabolism of Tretinoin can be decreased when combined with Fluvastatin.
Flecainide Flecainide The metabolism of Flecainide can be decreased when combined with Fluvastatin.
Certolizumab Injection Certolizumab Injection The metabolism of Fluvastatin can be increased when combined with Certolizumab pegol.
Ixabepilone Injection Ixabepilone Injection The metabolism of Ixabepilone can be decreased when combined with Fluvastatin.
Irinotecan Injection Irinotecan Injection The metabolism of Irinotecan can be decreased when combined with Fluvastatin.
Daptomycin Injection Daptomycin Injection The risk or severity of myopathy can be increased when Fluvastatin is combined with Daptomycin.
Praziquantel Praziquantel The metabolism of Praziquantel can be decreased when combined with Fluvastatin.
Rufinamide Rufinamide The metabolism of Rufinamide can be decreased when combined with Fluvastatin.
Midazolam Midazolam The serum concentration of Midazolam can be increased when it is combined with Fluvastatin.
Naltrexone Injection Naltrexone Injection The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Naltrexone is combined with Fluvastatin.
Eltrombopag Eltrombopag The metabolism of Fluvastatin can be decreased when combined with Eltrombopag.
Dexlansoprazole Dexlansoprazole The metabolism of Dexlansoprazole can be decreased when combined with Fluvastatin.
Fesoterodine Fesoterodine The metabolism of Fesoterodine can be decreased when combined with Fluvastatin.
Betaxolol Betaxolol The metabolism of Fluvastatin can be decreased when combined with Betaxolol.
Iloperidone Iloperidone The metabolism of Iloperidone can be decreased when combined with Fluvastatin.
Prasugrel Prasugrel The metabolism of Prasugrel can be decreased when combined with Fluvastatin.
Lacosamide Lacosamide The metabolism of Lacosamide can be decreased when combined with Fluvastatin.
Everolimus Everolimus The metabolism of Everolimus can be decreased when combined with Fluvastatin.
Tolvaptan (low blood sodium) Tolvaptan (low blood sodium) The metabolism of Tolvaptan can be decreased when combined with Fluvastatin.
Dronedarone Dronedarone The metabolism of Dronedarone can be decreased when combined with Fluvastatin.
Palonosetron Injection Palonosetron Injection The metabolism of Fluvastatin can be decreased when combined with Palonosetron.
Saxagliptin Saxagliptin The metabolism of Saxagliptin can be decreased when combined with Fluvastatin.
Romidepsin Injection Romidepsin Injection The metabolism of Romidepsin can be decreased when combined with Fluvastatin.
Tapentadol Tapentadol The metabolism of Tapentadol can be decreased when combined with Fluvastatin.
Golimumab Injection Golimumab Injection The metabolism of Fluvastatin can be increased when combined with Golimumab.
Pazopanib Pazopanib Fluvastatin may increase the hepatotoxic activities of Pazopanib.
Pitavastatin Pitavastatin The metabolism of Pitavastatin can be decreased when combined with Fluvastatin.
Albendazole Albendazole The metabolism of Albendazole can be decreased when combined with Fluvastatin.
Levonorgestrel Levonorgestrel The metabolism of Fluvastatin can be decreased when combined with Levonorgestrel.
Oxymorphone Oxymorphone The metabolism of Oxymorphone can be decreased when combined with Fluvastatin.
Tocilizumab Injection Tocilizumab Injection The metabolism of Fluvastatin can be increased when combined with Tocilizumab.
Cabazitaxel Injection Cabazitaxel Injection The metabolism of Cabazitaxel can be decreased when combined with Fluvastatin.
Acetaminophen Injection Acetaminophen Injection The metabolism of Fluvastatin can be decreased when combined with Acetaminophen.
Vilazodone Vilazodone The metabolism of Vilazodone can be decreased when combined with Fluvastatin.
Busulfan Injection Busulfan Injection The metabolism of Busulfan can be decreased when combined with Fluvastatin.
Roflumilast Roflumilast The metabolism of Roflumilast can be decreased when combined with Fluvastatin.
Linagliptin Linagliptin The metabolism of Linagliptin can be decreased when combined with Fluvastatin.
Rilpivirine Rilpivirine The metabolism of Fluvastatin can be decreased when combined with Rilpivirine.
Telaprevir Telaprevir The metabolism of Fluvastatin can be decreased when combined with Glecaprevir.
Cyclophosphamide Injection Cyclophosphamide Injection The metabolism of Cyclophosphamide can be decreased when combined with Fluvastatin.
Abiraterone Abiraterone The metabolism of Fluvastatin can be decreased when combined with Abiraterone.
Rivaroxaban Rivaroxaban The metabolism of Rivaroxaban can be decreased when combined with Fluvastatin.
Ticagrelor Ticagrelor The metabolism of Fluvastatin can be decreased when combined with Ticagrelor.
Brentuximab Vedotin Injection Brentuximab Vedotin Injection The metabolism of Brentuximab vedotin can be decreased when combined with Fluvastatin.
Ruxolitinib Ruxolitinib The metabolism of Ruxolitinib can be decreased when combined with Fluvastatin.
Vandetanib Vandetanib The metabolism of Vandetanib can be decreased when combined with Fluvastatin.
Clobazam Clobazam The metabolism of Clobazam can be decreased when combined with Fluvastatin.
Vemurafenib Vemurafenib The metabolism of Fluvastatin can be decreased when combined with Vemurafenib.
Vismodegib Vismodegib The metabolism of Fluvastatin can be decreased when combined with Vismodegib.
Ivacaftor Ivacaftor The metabolism of Ivacaftor can be decreased when combined with Fluvastatin.
Axitinib Axitinib The metabolism of Axitinib can be decreased when combined with Fluvastatin.
Crizotinib Crizotinib The metabolism of Fluvastatin can be decreased when combined with Crizotinib.
Cabergoline Cabergoline The metabolism of Cabergoline can be decreased when combined with Fluvastatin.
Ambrisentan Ambrisentan The metabolism of Ambrisentan can be decreased when combined with Fluvastatin.
Iloprost Iloprost The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Iloprost is combined with Fluvastatin.
Enzalutamide Enzalutamide The metabolism of Enzalutamide can be decreased when combined with Fluvastatin.
Mirabegron Mirabegron The metabolism of Mirabegron can be decreased when combined with Fluvastatin.
Regorafenib Regorafenib The metabolism of Fluvastatin can be decreased when combined with Regorafenib.
Bosutinib Bosutinib The metabolism of Fluvastatin can be decreased when combined with Bosutinib.
Teriflunomide Teriflunomide The metabolism of Fluvastatin can be decreased when combined with Teriflunomide.
Cabozantinib (thyroid cancer) Cabozantinib (thyroid cancer) The metabolism of Cabozantinib can be decreased when combined with Fluvastatin.
Tofacitinib Tofacitinib The metabolism of Tofacitinib can be decreased when combined with Fluvastatin.
Alogliptin Alogliptin The metabolism of Alogliptin can be decreased when combined with Fluvastatin.
Ponatinib Ponatinib The metabolism of Ponatinib can be decreased when combined with Fluvastatin.
Pomalidomide Pomalidomide The metabolism of Pomalidomide can be decreased when combined with Fluvastatin.
Ado-trastuzumab Emtansine Injection Ado-trastuzumab Emtansine Injection The metabolism of Trastuzumab emtansine can be decreased when combined with Fluvastatin.
Apixaban Apixaban The metabolism of Apixaban can be decreased when combined with Fluvastatin.
Dabrafenib Dabrafenib The metabolism of Fluvastatin can be decreased when combined with Dabrafenib.
Ospemifene Ospemifene The metabolism of Ospemifene can be decreased when combined with Fluvastatin.
Trametinib Trametinib The metabolism of Fluvastatin can be decreased when combined with Trametinib.
Levomilnacipran Levomilnacipran The metabolism of Levomilnacipran can be decreased when combined with Fluvastatin.
Vortioxetine Vortioxetine The metabolism of Vortioxetine can be decreased when combined with Fluvastatin.
Perampanel Perampanel The metabolism of Perampanel can be increased when combined with Fluvastatin.
Ibrutinib Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Fluvastatin.
Lomitapide Lomitapide The metabolism of Lomitapide can be decreased when combined with Fluvastatin.
Ketorolac Injection Ketorolac Injection The metabolism of Ketorolac can be decreased when combined with Fluvastatin.
Simeprevir Simeprevir The excretion of Simeprevir can be decreased when combined with Fluvastatin.
Dapagliflozin Dapagliflozin The metabolism of Dapagliflozin can be decreased when combined with Fluvastatin.
Apremilast Apremilast The metabolism of Fluvastatin can be increased when combined with Apremilast.
Ceritinib Ceritinib The metabolism of Fluvastatin can be decreased when combined with Ceritinib.
Siltuximab Injection Siltuximab Injection The metabolism of Fluvastatin can be increased when combined with Siltuximab.
Idelalisib Idelalisib The metabolism of Fluvastatin can be decreased when combined with Idelalisib.
Testosterone Injection Testosterone Injection The metabolism of Fluvastatin can be decreased when combined with Testosterone.
Oritavancin Injection Oritavancin Injection The metabolism of Fluvastatin can be decreased when combined with Oritavancin.
Vorapaxar Vorapaxar The metabolism of Vorapaxar can be decreased when combined with Fluvastatin.
Hydrocodone Hydrocodone The metabolism of Hydrocodone can be increased when combined with Fluvastatin.
Suvorexant Suvorexant The metabolism of Suvorexant can be decreased when combined with Fluvastatin.
Olaparib Olaparib The metabolism of Olaparib can be decreased when combined with Fluvastatin.
Caspofungin Injection Caspofungin Injection The excretion of Fluvastatin can be decreased when combined with Caspofungin.
Methamphetamine Methamphetamine The metabolism of Metamfetamine can be decreased when combined with Fluvastatin.
Tasimelteon Tasimelteon The metabolism of Tasimelteon can be decreased when combined with Fluvastatin.
Riociguat Riociguat The metabolism of Riociguat can be decreased when combined with Fluvastatin.
Nintedanib Nintedanib The metabolism of Nintedanib can be decreased when combined with Fluvastatin.
Secukinumab Injection Secukinumab Injection The metabolism of Fluvastatin can be increased when combined with Secukinumab.
Risperidone Injection Risperidone Injection The metabolism of Fluvastatin can be decreased when combined with Risperidone.
Palbociclib Palbociclib The metabolism of Palbociclib can be decreased when combined with Fluvastatin.
Lenvatinib Lenvatinib The metabolism of Fluvastatin can be decreased when combined with Lenvatinib.
Naloxegol Naloxegol The metabolism of Fluvastatin can be decreased when combined with Naloxegol.
Panobinostat Panobinostat The metabolism of Panobinostat can be decreased when combined with Fluvastatin.
Haloperidol Injection Haloperidol Injection The serum concentration of Fluvastatin can be increased when it is combined with Haloperidol.
Sonidegib Sonidegib The metabolism of Sonidegib can be decreased when combined with Fluvastatin.
Rolapitant Rolapitant The metabolism of Rolapitant can be decreased when combined with Fluvastatin.
Daclatasvir Daclatasvir The serum concentration of Fluvastatin can be increased when it is combined with Daclatasvir.
Brexpiprazole Brexpiprazole The metabolism of Brexpiprazole can be decreased when combined with Fluvastatin.
Ziprasidone Injection Ziprasidone Injection The metabolism of Ziprasidone can be decreased when combined with Fluvastatin.
Cariprazine Cariprazine The metabolism of Cariprazine can be decreased when combined with Fluvastatin.
Eluxadoline Eluxadoline The serum concentration of Eluxadoline can be increased when it is combined with Fluvastatin.
Cobimetinib Cobimetinib The metabolism of Cobimetinib can be decreased when combined with Fluvastatin.
Trabectedin Injection Trabectedin Injection The risk or severity of myopathy and rhabdomyolysis can be increased when Fluvastatin is combined with Trabectedin.
Osimertinib Osimertinib The metabolism of Osimertinib can be decreased when combined with Fluvastatin.
Alectinib Alectinib The metabolism of Alectinib can be decreased when combined with Fluvastatin.
Ixazomib Ixazomib The metabolism of Ixazomib can be decreased when combined with Fluvastatin.
Rifapentine Rifapentine The metabolism of Fluvastatin can be increased when combined with Rifapentine.
Lesinurad Lesinurad The metabolism of Lesinurad can be decreased when combined with Fluvastatin.
Amphotericin B Liposomal Injection Amphotericin B Liposomal Injection The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Amphotericin B is combined with Fluvastatin.
Dexamethasone Injection Dexamethasone Injection The metabolism of Fluvastatin can be increased when combined with Dexamethasone.
Brivaracetam Injection Brivaracetam Injection The metabolism of Brivaracetam can be decreased when combined with Fluvastatin.
Venetoclax Venetoclax The metabolism of Fluvastatin can be decreased when combined with Venetoclax.
Cobicistat Cobicistat The metabolism of Fluvastatin can be decreased when combined with Cobicistat.
Selexipag Selexipag The metabolism of Selexipag can be decreased when combined with Fluvastatin.
Diphenhydramine Injection Diphenhydramine Injection The metabolism of Diphenhydramine can be decreased when combined with Fluvastatin.
Rucaparib Rucaparib The metabolism of Fluvastatin can be decreased when combined with Rucaparib.
Ribociclib Ribociclib The metabolism of Ribociclib can be decreased when combined with Fluvastatin.
Brigatinib Brigatinib The metabolism of Brigatinib can be decreased when combined with Fluvastatin.
Doxepin (Insomnia) Doxepin (Insomnia) The metabolism of Doxepin can be decreased when combined with Fluvastatin.
Deutetrabenazine Deutetrabenazine The metabolism of Deutetrabenazine can be decreased when combined with Fluvastatin.
Valbenazine Valbenazine The metabolism of Valbenazine can be decreased when combined with Fluvastatin.
Deflazacort Deflazacort The metabolism of Fluvastatin can be increased when combined with Deflazacort.
Safinamide Safinamide The metabolism of Fluvastatin can be decreased when combined with Safinamide.
Midostaurin Midostaurin The metabolism of Fluvastatin can be decreased when combined with Midostaurin.
Neratinib Neratinib The metabolism of Neratinib can be decreased when combined with Fluvastatin.
Enasidenib Enasidenib The metabolism of Fluvastatin can be decreased when combined with Enasidenib.
Aprepitant/Fosaprepitant Injection Aprepitant/Fosaprepitant Injection The metabolism of Fosaprepitant can be decreased when combined with Fluvastatin.
Copanlisib Injection Copanlisib Injection The metabolism of Copanlisib can be decreased when combined with Fluvastatin.
Delafloxacin Delafloxacin The metabolism of Fluvastatin can be increased when combined with Delafloxacin.
Abemaciclib Abemaciclib The metabolism of Abemaciclib can be decreased when combined with Fluvastatin.
Acalabrutinib Acalabrutinib The metabolism of Fluvastatin can be decreased when combined with Acalabrutinib.
Letermovir Letermovir The metabolism of Fluvastatin can be decreased when combined with Letermovir.
Tetrabenazine Tetrabenazine The metabolism of Tetrabenazine can be decreased when combined with Fluvastatin.
Ertugliflozin Ertugliflozin The metabolism of Fluvastatin can be decreased when combined with Ertugliflozin.
Buprenorphine Injection Buprenorphine Injection The metabolism of Buprenorphine can be decreased when combined with Fluvastatin.
Apalutamide Apalutamide The metabolism of Fluvastatin can be decreased when combined with Apalutamide.
Penicillamine Penicillamine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Penicillamine is combined with Fluvastatin.
Fostamatinib Fostamatinib The metabolism of Fluvastatin can be decreased when combined with Fostamatinib.
Avatrombopag Avatrombopag The metabolism of Fluvastatin can be increased when combined with Avatrombopag.
Baricitinib Baricitinib The metabolism of Fluvastatin can be decreased when combined with Baricitinib.
Lofexidine Lofexidine The metabolism of Lofexidine can be decreased when combined with Fluvastatin.
Eliglustat Eliglustat The metabolism of Eliglustat can be decreased when combined with Fluvastatin.
Encorafenib Encorafenib The metabolism of Encorafenib can be decreased when combined with Fluvastatin.
Ivosidenib Ivosidenib The metabolism of Ivosidenib can be decreased when combined with Fluvastatin.
Elagolix Elagolix The metabolism of Elagolix can be decreased when combined with Fluvastatin.
Doravirine Doravirine The metabolism of Doravirine can be decreased when combined with Fluvastatin.
Tafenoquine Tafenoquine The metabolism of Tafenoquine can be decreased when combined with Fluvastatin.
Cannabidiol Cannabidiol The metabolism of Cannabidiol can be decreased when combined with Fluvastatin.
Dacomitinib Dacomitinib The metabolism of Fluvastatin can be decreased when combined with Dacomitinib.
Duvelisib Duvelisib The metabolism of Duvelisib can be decreased when combined with Fluvastatin.
Stiripentol Stiripentol The metabolism of Fluvastatin can be decreased when combined with Stiripentol.
Gilteritinib Gilteritinib The metabolism of Gilteritinib can be decreased when combined with Fluvastatin.
Glasdegib Glasdegib The metabolism of Glasdegib can be decreased when combined with Fluvastatin.
Lorlatinib Lorlatinib The metabolism of Lorlatinib can be decreased when combined with Fluvastatin.
Paclitaxel (with albumin) Injection Paclitaxel (with albumin) Injection The metabolism of Paclitaxel can be decreased when combined with Fluvastatin.
Rifamycin Rifamycin The metabolism of Fluvastatin can be decreased when combined with Rifamycin.
Prucalopride Prucalopride The metabolism of Prucalopride can be decreased when combined with Fluvastatin.
Emapalumab-lzsg Injection Emapalumab-lzsg Injection The metabolism of Fluvastatin can be increased when combined with Emapalumab.
Siponimod Siponimod The metabolism of Siponimod can be decreased when combined with Fluvastatin.
Erdafitinib Erdafitinib The metabolism of Erdafitinib can be decreased when combined with Fluvastatin.
Esomeprazole Injection Esomeprazole Injection The metabolism of Esomeprazole can be decreased when combined with Fluvastatin.
Alpelisib Alpelisib The serum concentration of Fluvastatin can be decreased when it is combined with Alpelisib.
Cladribine Cladribine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Cladribine is combined with Fluvastatin.
Selinexor Selinexor The excretion of Fluvastatin can be decreased when combined with Selinexor.
Triclabendazole Triclabendazole The metabolism of Fluvastatin can be decreased when combined with Triclabendazole.
Entrectinib Entrectinib The metabolism of Entrectinib can be decreased when combined with Fluvastatin.
Pexidartinib Pexidartinib The metabolism of Fluvastatin can be decreased when combined with Pexidartinib.
Istradefylline Istradefylline The metabolism of Istradefylline can be decreased when combined with Fluvastatin.
Pitolisant Pitolisant The serum concentration of Fluvastatin can be decreased when it is combined with Pitolisant.
Fedratinib Fedratinib The metabolism of Fluvastatin can be decreased when combined with Fedratinib.
Lefamulin Lefamulin The metabolism of Lefamulin can be decreased when combined with Fluvastatin.
Phenytoin Injection Phenytoin Injection The serum concentration of Phenytoin can be increased when it is combined with Fluvastatin.
Fosphenytoin Injection Fosphenytoin Injection The serum concentration of Fosphenytoin can be increased when it is combined with Fluvastatin.
Zanubrutinib Zanubrutinib The metabolism of Zanubrutinib can be decreased when combined with Fluvastatin.
Voxelotor Voxelotor The serum concentration of Voxelotor can be increased when it is combined with Fluvastatin.
Avapritinib Avapritinib The metabolism of Avapritinib can be decreased when combined with Fluvastatin.
Tazemetostat Tazemetostat The metabolism of Tazemetostat can be decreased when combined with Fluvastatin.
Bempedoic Acid Bempedoic Acid The excretion of Fluvastatin can be decreased when combined with Bempedoic acid.
Cenobamate Cenobamate The serum concentration of Fluvastatin can be decreased when it is combined with Cenobamate.
Ozanimod Ozanimod The metabolism of Ozanimod can be decreased when combined with Fluvastatin.
Selumetinib Selumetinib The metabolism of Selumetinib can be decreased when combined with Fluvastatin.
Tucatinib Tucatinib The metabolism of Tucatinib can be decreased when combined with Fluvastatin.
Remdesivir Injection Remdesivir Injection The excretion of Remdesivir can be decreased when combined with Fluvastatin.
Selpercatinib Selpercatinib The serum concentration of Fluvastatin can be increased when it is combined with Selpercatinib.
Lemborexant Lemborexant The metabolism of Lemborexant can be decreased when combined with Fluvastatin.
Fenfluramine Fenfluramine The metabolism of Fluvastatin can be decreased when combined with Fenfluramine.
Fostemsavir Fostemsavir The serum concentration of Fluvastatin can be increased when it is combined with Fostemsavir.
Belantamab Mafodotin-blmf Injection Belantamab Mafodotin-blmf Injection The excretion of Belantamab mafodotin can be decreased when combined with Fluvastatin.
Pralsetinib Pralsetinib The metabolism of Fluvastatin can be decreased when combined with Pralsetinib.
Opicapone Opicapone The metabolism of Fluvastatin can be decreased when combined with Opicapone.
Satralizumab-mwge Injection Satralizumab-mwge Injection The serum concentration of Fluvastatin can be decreased when it is combined with Satralizumab.
Progestin-Only (drospirenone) Oral Contraceptives Progestin-Only (drospirenone) Oral Contraceptives The metabolism of Drospirenone can be decreased when combined with Fluvastatin.
Theophylline Theophylline The metabolism of Theophylline can be decreased when combined with Fluvastatin.
Indomethacin Indomethacin The metabolism of Indomethacin can be decreased when combined with Fluvastatin.
Mefenamic Acid Mefenamic Acid The metabolism of Fluvastatin can be decreased when combined with Mefenamic acid.
Naproxen Naproxen The metabolism of Naproxen can be decreased when combined with Fluvastatin.
Trazodone Trazodone The metabolism of Fluvastatin can be decreased when combined with Trazodone.
Isotretinoin Isotretinoin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Isotretinoin is combined with Fluvastatin.
Hydroxyurea Hydroxyurea The metabolism of Fluvastatin can be decreased when combined with Hydroxyurea.
Floxuridine Floxuridine The metabolism of Fluvastatin can be decreased when combined with Floxuridine.
Phenobarbital Phenobarbital The metabolism of Phenobarbital can be decreased when combined with Fluvastatin.
Methotrexate Injection Methotrexate Injection The metabolism of Fluvastatin can be decreased when combined with Methotrexate.
Primidone Primidone The metabolism of Primidone can be decreased when combined with Fluvastatin.
Methsuximide Methsuximide The metabolism of Methsuximide can be decreased when combined with Fluvastatin.
Chlorpromazine Chlorpromazine The metabolism of Chlorpromazine can be decreased when combined with Fluvastatin.
Diazepam Diazepam The metabolism of Fluvastatin can be decreased when combined with Diazepam.
Lorazepam Lorazepam The metabolism of Lorazepam can be decreased when combined with Fluvastatin.
Codeine Codeine The metabolism of Fluvastatin can be decreased when combined with Codeine.
Tranylcypromine Tranylcypromine The metabolism of Fluvastatin can be decreased when combined with Tranylcypromine.
Phenelzine Phenelzine The metabolism of Fluvastatin can be decreased when combined with Phenelzine.
Procarbazine Procarbazine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Fluvastatin is combined with Procarbazine.
Minocycline Minocycline The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Minocycline is combined with Fluvastatin.
Prochlorperazine Prochlorperazine The metabolism of Prochlorperazine can be decreased when combined with Fluvastatin.
Thioridazine Thioridazine The metabolism of Fluvastatin can be decreased when combined with Thioridazine.
Dapsone Dapsone The metabolism of Dapsone can be decreased when combined with Fluvastatin.
Sulfadiazine Sulfadiazine The metabolism of Sulfadiazine can be decreased when combined with Fluvastatin.
Oxycodone Oxycodone The metabolism of Fluvastatin can be decreased when combined with Oxycodone.
Methadone Methadone The metabolism of Methadone can be decreased when combined with Fluvastatin.
Oxybutynin Oxybutynin The metabolism of Fluvastatin can be decreased when combined with Oxybutynin.
Benztropine Benztropine The metabolism of Fluvastatin can be decreased when combined with Benzatropine.
Colestipol Colestipol Colestipol can cause a decrease in the absorption of Fluvastatin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Maprotiline Maprotiline The metabolism of Fluvastatin can be decreased when combined with Maprotiline.
Ibuprofen Ibuprofen The metabolism of Ibuprofen can be decreased when combined with Fluvastatin.
Orphenadrine Orphenadrine The metabolism of Fluvastatin can be decreased when combined with Orphenadrine.
Perphenazine Perphenazine The metabolism of Fluvastatin can be decreased when combined with Perphenazine.
Fluphenazine Fluphenazine The metabolism of Fluvastatin can be decreased when combined with Fluphenazine.
Phentermine Phentermine The metabolism of Phentermine can be decreased when combined with Fluvastatin.
Amoxapine Amoxapine The metabolism of Fluvastatin can be decreased when combined with Amoxapine.
Sulfasalazine Sulfasalazine The excretion of Fluvastatin can be decreased when combined with Sulfasalazine.
Hydrocortisone Hydrocortisone The metabolism of Fluvastatin can be increased when combined with Hydrocortisone.
Doxorubicin Doxorubicin The metabolism of Fluvastatin can be decreased when combined with Doxorubicin.
Cytarabine Cytarabine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Cytarabine is combined with Fluvastatin.
Carbamazepine Carbamazepine The metabolism of Carbamazepine can be decreased when combined with Fluvastatin.
Methyldopa Methyldopa The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Methyldopa is combined with Fluvastatin.
Clonidine Clonidine The metabolism of Fluvastatin can be decreased when combined with Clonidine.
Cimetidine Cimetidine The metabolism of Fluvastatin can be decreased when combined with Cimetidine.
Warfarin Warfarin The metabolism of Warfarin can be decreased when combined with Fluvastatin.
Loperamide Loperamide The metabolism of Loperamide can be increased when combined with Fluvastatin.
Promethazine Promethazine The metabolism of Fluvastatin can be decreased when combined with Promethazine.
Daunorubicin Daunorubicin The metabolism of Fluvastatin can be increased when combined with Daunorubicin.
Griseofulvin Griseofulvin The metabolism of Fluvastatin can be increased when combined with Griseofulvin.
Digoxin Digoxin The excretion of Fluvastatin can be decreased when combined with Digoxin.
Chloroquine Chloroquine The metabolism of Chloroquine can be decreased when combined with Fluvastatin.
Quinine Quinine The metabolism of Quinine can be decreased when combined with Fluvastatin.
Sulfinpyrazone Sulfinpyrazone The metabolism of Fluvastatin can be decreased when combined with Sulfinpyrazone.
Clindamycin Injection Clindamycin Injection The metabolism of Clindamycin can be decreased when combined with Fluvastatin.
Secobarbital Secobarbital The metabolism of Fluvastatin can be increased when combined with Secobarbital.
Desipramine Desipramine The metabolism of Desipramine can be decreased when combined with Fluvastatin.
Amitriptyline Amitriptyline The metabolism of Amitriptyline can be decreased when combined with Fluvastatin.
Imipramine Imipramine The metabolism of Imipramine can be decreased when combined with Fluvastatin.
Probenecid Probenecid The metabolism of Fluvastatin can be decreased when combined with Probenecid.
Quinidine Quinidine The metabolism of Fluvastatin can be decreased when combined with Quinidine.
Procainamide Procainamide The metabolism of Procainamide can be decreased when combined with Fluvastatin.
Isoniazid Isoniazid The metabolism of Fluvastatin can be decreased when combined with Isoniazid.
Rifampin Rifampin The metabolism of Fluvastatin can be increased when combined with Rifampicin.
Valproic Acid Valproic Acid The metabolism of Fluvastatin can be decreased when combined with Valproic acid.
Tamoxifen Tamoxifen The metabolism of Fluvastatin can be decreased when combined with Tamoxifen.
Levothyroxine Levothyroxine The metabolism of Fluvastatin can be decreased when combined with Levothyroxine.
Liothyronine Liothyronine The excretion of Liothyronine can be decreased when combined with Fluvastatin.
Methimazole Methimazole The metabolism of Fluvastatin can be decreased when combined with Methimazole.
Propylthiouracil Propylthiouracil The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Propylthiouracil is combined with Fluvastatin.
Chlorpropamide Chlorpropamide The metabolism of Chlorpropamide can be decreased when combined with Fluvastatin.
Tolbutamide Tolbutamide The metabolism of Tolbutamide can be decreased when combined with Fluvastatin.
Tolazamide Tolazamide The metabolism of Tolazamide can be decreased when combined with Fluvastatin.
Dextromethorphan Dextromethorphan The metabolism of Fluvastatin can be decreased when combined with Dextromethorphan.
Dinoprostone Dinoprostone The excretion of Dinoprostone can be decreased when combined with Fluvastatin.
Niacin Niacin The risk or severity of myopathy and rhabdomyolysis can be increased when Niacin is combined with Fluvastatin.
Baclofen Baclofen The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Fluvastatin.
Clemastine Clemastine The metabolism of Fluvastatin can be decreased when combined with Clemastine.
Chlorpheniramine Chlorpheniramine The metabolism of Chlorpheniramine can be decreased when combined with Fluvastatin.
Brompheniramine Brompheniramine The metabolism of Brompheniramine can be increased when combined with Fluvastatin.
Meclizine Meclizine The metabolism of Fluvastatin can be decreased when combined with Meclizine.
Chlorzoxazone Chlorzoxazone The metabolism of Fluvastatin can be decreased when combined with Chlorzoxazone.
Carisoprodol Carisoprodol The metabolism of Carisoprodol can be decreased when combined with Fluvastatin.
Danazol Danazol The serum concentration of Fluvastatin can be increased when it is combined with Danazol.
Disulfiram Disulfiram The metabolism of Fluvastatin can be decreased when combined with Disulfiram.
Nortriptyline Nortriptyline The metabolism of Nortriptyline can be decreased when combined with Fluvastatin.
Spironolactone Spironolactone The metabolism of Fluvastatin can be decreased when combined with Spironolactone.
Amphotericin B Injection Amphotericin B Injection The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Amphotericin B is combined with Fluvastatin.
Nadolol Nadolol The metabolism of Nadolol can be decreased when combined with Fluvastatin.
Cholestyramine Resin Cholestyramine Resin The serum concentration of Fluvastatin can be decreased when it is combined with Cholestyramine.
Fluorouracil Injection Fluorouracil Injection The metabolism of Fluorouracil can be decreased when combined with Fluvastatin.
Colchicine Colchicine The metabolism of Colchicine can be decreased when combined with Fluvastatin.
Cephalexin Cephalexin The metabolism of Cephalexin can be decreased when combined with Fluvastatin.
Nystatin Nystatin The excretion of Fluvastatin can be decreased when combined with Nystatin.
Ketoconazole Ketoconazole The metabolism of Fluvastatin can be decreased when combined with Ketoconazole.
Thiotepa Injection Thiotepa Injection The metabolism of Thiotepa can be decreased when combined with Fluvastatin.
Vincristine Injection Vincristine Injection The metabolism of Fluvastatin can be decreased when combined with Vincristine.
Captopril Captopril The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Fluvastatin is combined with Captopril.
Dipyridamole Dipyridamole The excretion of Fluvastatin can be decreased when combined with Dipyridamole.
Vinblastine Vinblastine The metabolism of Fluvastatin can be decreased when combined with Vinblastine.
Metoprolol Metoprolol The metabolism of Metoprolol can be decreased when combined with Fluvastatin.
Hydroxyzine Hydroxyzine The metabolism of Fluvastatin can be decreased when combined with Hydroxyzine.
Aspirin Aspirin The metabolism of Acetylsalicylic acid can be decreased when combined with Fluvastatin.
Alprazolam Alprazolam The metabolism of Alprazolam can be decreased when combined with Fluvastatin.
Triazolam Triazolam The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Triazolam is combined with Fluvastatin.
Trimethoprim Trimethoprim The metabolism of Trimethoprim can be decreased when combined with Fluvastatin.
Diltiazem Diltiazem The metabolism of Fluvastatin can be decreased when combined with Diltiazem.
Nifedipine Nifedipine The metabolism of Fluvastatin can be decreased when combined with Nifedipine.
Timolol Timolol The metabolism of Timolol can be decreased when combined with Fluvastatin.
Verapamil Verapamil The metabolism of Verapamil can be decreased when combined with Fluvastatin.
Atenolol Atenolol The metabolism of Fluvastatin can be decreased when combined with Atenolol.
Pindolol Pindolol The metabolism of Fluvastatin can be decreased when combined with Pindolol.
Cisplatin Injection Cisplatin Injection The metabolism of Fluvastatin can be decreased when combined with Cisplatin.
Piroxicam Piroxicam The metabolism of Piroxicam can be decreased when combined with Fluvastatin.
Bumetanide Bumetanide The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Bumetanide is combined with Fluvastatin.
Etoposide Etoposide The metabolism of Fluvastatin can be decreased when combined with Etoposide.
Glyburide Glyburide The metabolism of Fluvastatin can be decreased when combined with Glyburide.
Glipizide Glipizide The metabolism of Glipizide can be decreased when combined with Fluvastatin.
Pentamidine Injection Pentamidine Injection The metabolism of Fluvastatin can be decreased when combined with Pentamidine.
Labetalol Labetalol The metabolism of Fluvastatin can be decreased when combined with Labetalol.
Leuprolide Injection Leuprolide Injection The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Leuprolide is combined with Fluvastatin.
Gemfibrozil Gemfibrozil The risk or severity of rhabdomyolysis, myoglobinuria, and elevated creatine kinase (CPK) can be increased when Gemfibrozil is combined with Fluvastatin.
Ketoprofen Ketoprofen The metabolism of Fluvastatin can be decreased when combined with Ketoprofen.
Pimozide Pimozide The metabolism of Pimozide can be decreased when combined with Fluvastatin.
Enalapril Enalapril The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Enalapril is combined with Fluvastatin.
Flurbiprofen Flurbiprofen The metabolism of Fluvastatin can be decreased when combined with Flurbiprofen.
Amiodarone Amiodarone The metabolism of Fluvastatin can be increased when combined with Amiodarone.
Buspirone Buspirone The metabolism of Fluvastatin can be decreased when combined with Buspirone.
Lovastatin Lovastatin The metabolism of Lovastatin can be decreased when combined with Fluvastatin.
Ciprofloxacin Ciprofloxacin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ciprofloxacin is combined with Fluvastatin.
Diclofenac Diclofenac The metabolism of Diclofenac can be decreased when combined with Fluvastatin.
Fluoxetine Fluoxetine The serum concentration of Fluvastatin can be increased when it is combined with Fluoxetine.
Clozapine Clozapine The metabolism of Clozapine can be decreased when combined with Fluvastatin.
Idarubicin Idarubicin The metabolism of Idarubicin can be decreased when combined with Fluvastatin.
Ofloxacin Ofloxacin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Fluvastatin is combined with Ofloxacin.
Clarithromycin Clarithromycin The metabolism of Fluvastatin can be decreased when combined with Clarithromycin.
Etodolac Etodolac The metabolism of Etodolac can be decreased when combined with Fluvastatin.
Felodipine Felodipine The metabolism of Fluvastatin can be decreased when combined with Felodipine.
Nabumetone Nabumetone The metabolism of Nabumetone can be decreased when combined with Fluvastatin.
Pravastatin Pravastatin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Pravastatin is combined with Fluvastatin.
Simvastatin Simvastatin The metabolism of Fluvastatin can be decreased when combined with Simvastatin.
Teniposide Injection Teniposide Injection The metabolism of Fluvastatin can be decreased when combined with Teniposide.
Itraconazole Itraconazole The metabolism of Fluvastatin can be decreased when combined with Itraconazole.
Atovaquone Atovaquone The metabolism of Fluvastatin can be decreased when combined with Atovaquone.
Rifabutin Rifabutin The metabolism of Fluvastatin can be increased when combined with Rifabutin.
Sotalol Sotalol The metabolism of Sotalol can be decreased when combined with Fluvastatin.
Zolpidem Zolpidem The metabolism of Zolpidem can be decreased when combined with Fluvastatin.
Doxazosin Doxazosin The metabolism of Doxazosin can be decreased when combined with Fluvastatin.
Omeprazole Omeprazole The metabolism of Omeprazole can be decreased when combined with Fluvastatin.
Cisapride Cisapride The metabolism of Fluvastatin can be decreased when combined with Cisapride.
Venlafaxine Venlafaxine The metabolism of Venlafaxine can be decreased when combined with Fluvastatin.
Nizatidine Nizatidine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Nizatidine is combined with Fluvastatin.
Stavudine Stavudine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Stavudine is combined with Fluvastatin.
Famciclovir Famciclovir The metabolism of Famciclovir can be decreased when combined with Fluvastatin.
Fluvoxamine Fluvoxamine The metabolism of Fluvastatin can be decreased when combined with Fluvoxamine.
Nefazodone Nefazodone The excretion of Fluvastatin can be decreased when combined with Nefazodone.
Lamotrigine Lamotrigine The metabolism of Fluvastatin can be increased when combined with Lamotrigine.
Losartan Losartan The metabolism of Fluvastatin can be decreased when combined with Losartan.
Tramadol Tramadol The metabolism of Tramadol can be decreased when combined with Fluvastatin.
Vinorelbine Injection Vinorelbine Injection The metabolism of Fluvastatin can be decreased when combined with Vinorelbine.
Lansoprazole Lansoprazole The metabolism of Lansoprazole can be decreased when combined with Fluvastatin.
Ifosfamide Injection Ifosfamide Injection The metabolism of Ifosfamide can be decreased when combined with Fluvastatin.
Nicardipine Nicardipine The metabolism of Fluvastatin can be decreased when combined with Nicardipine.
Bupropion Bupropion The metabolism of Fluvastatin can be decreased when combined with Bupropion.
Ticlopidine Ticlopidine The metabolism of Ticlopidine can be decreased when combined with Fluvastatin.
Saquinavir Saquinavir The metabolism of Fluvastatin can be decreased when combined with Saquinavir.
Metformin Metformin Metformin may increase the hypolipidaemic activities of Fluvastatin.
Nisoldipine Nisoldipine The metabolism of Fluvastatin can be decreased when combined with Nisoldipine.
Lamivudine Lamivudine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Lamivudine is combined with Fluvastatin.
Glimepiride Glimepiride The metabolism of Glimepiride can be decreased when combined with Fluvastatin.
Anastrozole Anastrozole The metabolism of Fluvastatin can be decreased when combined with Anastrozole.
Indinavir Indinavir The metabolism of Fluvastatin can be decreased when combined with Indinavir.
Ritonavir Ritonavir The serum concentration of Fluvastatin can be increased when it is combined with Ritonavir.
Docetaxel Injection Docetaxel Injection The metabolism of Docetaxel can be decreased when combined with Fluvastatin.
Clomipramine Clomipramine The metabolism of Clomipramine can be decreased when combined with Fluvastatin.
Zafirlukast Zafirlukast The metabolism of Fluvastatin can be decreased when combined with Zafirlukast.
Mirtazapine Mirtazapine The metabolism of Fluvastatin can be decreased when combined with Mirtazapine.
Zileuton Zileuton The metabolism of Zileuton can be decreased when combined with Fluvastatin.
Valsartan Valsartan The metabolism of Fluvastatin can be decreased when combined with Valsartan.
Donepezil Donepezil The metabolism of Donepezil can be decreased when combined with Fluvastatin.
Nelfinavir Nelfinavir The metabolism of Nelfinavir can be decreased when combined with Fluvastatin.
Fexofenadine Fexofenadine The excretion of Fexofenadine can be decreased when combined with Fluvastatin.
Azithromycin Azithromycin The metabolism of Azithromycin can be decreased when combined with Fluvastatin.
Loratadine Loratadine The metabolism of Fluvastatin can be decreased when combined with Loratadine.
Carvedilol Carvedilol The metabolism of Carvedilol can be decreased when combined with Fluvastatin.
Nilutamide Nilutamide The metabolism of Fluvastatin can be decreased when combined with Nilutamide.
Flutamide Flutamide The metabolism of Fluvastatin can be decreased when combined with Flutamide.
Selegiline Selegiline The metabolism of Selegiline can be decreased when combined with Fluvastatin.
Bicalutamide Bicalutamide The metabolism of Fluvastatin can be decreased when combined with Bicalutamide.
Sertraline Sertraline The metabolism of Sertraline can be decreased when combined with Fluvastatin.
Propafenone Propafenone The metabolism of Fluvastatin can be decreased when combined with Propafenone.
Letrozole Letrozole The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Letrozole is combined with Fluvastatin.
Raloxifene Raloxifene The metabolism of Fluvastatin can be decreased when combined with Raloxifene.
Irbesartan Irbesartan The metabolism of Fluvastatin can be decreased when combined with Irbesartan.
Tamsulosin Tamsulosin The metabolism of Fluvastatin can be decreased when combined with Tamsulosin.
Finasteride Finasteride The metabolism of Finasteride can be decreased when combined with Fluvastatin.
Quetiapine Quetiapine The metabolism of Quetiapine can be decreased when combined with Fluvastatin.
Paroxetine Paroxetine The metabolism of Fluvastatin can be decreased when combined with Paroxetine.
Tolcapone Tolcapone The metabolism of Fluvastatin can be decreased when combined with Tolcapone.
Citalopram Citalopram Fluvastatin may increase the QTc-prolonging activities of Citalopram.
Capecitabine Capecitabine The metabolism of Fluvastatin can be decreased when combined with Capecitabine.
Efavirenz Efavirenz The metabolism of Fluvastatin can be increased when combined with Efavirenz.
Sildenafil Sildenafil The metabolism of Fluvastatin can be decreased when combined with Sildenafil.
Pioglitazone Pioglitazone The metabolism of Pioglitazone can be decreased when combined with Fluvastatin.
Celecoxib Celecoxib The metabolism of Celecoxib can be decreased when combined with Fluvastatin.
Rosiglitazone Rosiglitazone The metabolism of Fluvastatin can be decreased when combined with Rosiglitazone.
Tolterodine Tolterodine The metabolism of Tolterodine can be decreased when combined with Fluvastatin.
Thalidomide Thalidomide The metabolism of Fluvastatin can be increased when combined with Thalidomide.
Colesevelam Colesevelam Colesevelam can cause a decrease in the absorption of Fluvastatin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Nateglinide Nateglinide The metabolism of Nateglinide can be decreased when combined with Fluvastatin.
Galantamine Galantamine The metabolism of Fluvastatin can be decreased when combined with Galantamine.
Rabeprazole Rabeprazole The metabolism of Fluvastatin can be decreased when combined with Rabeprazole.
Terbinafine Terbinafine The metabolism of Terbinafine can be decreased when combined with Fluvastatin.

Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists