Gefitinib

Generic name: Pronounced as (ge fi' ti nib)
Brand names
  • Iressa®
Click on drug name to hear pronunciation

Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 12/15/2015

Gefitinib is used to treat non-small cell lung cancer that has spread to other parts of the body in people with certain types of tumors. Gefitinib is in a class of medications called kinase inhibitors. It works by blocking the action of a certain naturally occurring substance that may be needed to help cancer cells multiply.

Gefitinib comes as a tablet to take by mouth. It is usually taken with or without food once a day. Take gefitinib at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take gefitinib exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

If you are unable to swallow the tablets, you may dissolve them in water. Place one tablet in 4 to 8 ounces (120 to 240 mL) of plain, noncarbonated drinking water. Stir with a spoon for about 15 minutes until the tablet is dissolved. Drink the mixture right away. Rinse the glass with another 4 to 8 ounces (120 to 240 mL) of water and drink the rinse water right away to be sure that you swallow all of the medication.

Your doctor may delay or permanently stop your treatment if you experience certain side effects. Be sure to tell your doctor how you are feeling during your treatment with gefitinib.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking gefitinib,

  • tell your doctor and pharmacist if you are allergic to gefitinib, any other medications, or any of the ingredients in gefitinib tablets. Ask your pharmacist for a list of the ingredients.

  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, and nutritional supplements you are taking or plan to take. Be sure to mention any of the following: anticoagulants ('blood thinners') such as warfarin (Coumadin, Jantoven); antifungals such as itraconazole (Onmel, Sporanox) and ketoconazole (Nizoral); metoprolol (Lopressor, Toprol XL, in Dutoprol); phenytoin (Dilantin, Phenytek); and tricyclic antidepressants such as imipramine (Tofranil) and amitriptyline. Many other medications may interact with gefitinib, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

  • if you are taking an antacid or an H2 blocker medication for indigestion, heartburn, or ulcers such as cimetidine (Tagamet), famotidine (Pepcid), nizatidine (Axid), or ranitidine (Zantac), take them at least 6 hours before or 6 hours after taking gefitinib.

  • if you are taking a proton pump inhibitor medication for indigestion, heartburn, or ulcers such as esomeprazole (Nexium), lansoprazole (Prevacid), omeprazole (Prilosec), pantoprazole (Protonix), or rabeprazole (AcipHex), take it at least 12 hours before or at least 12 hours after taking gefitinib.

  • tell your doctor if you have or have ever had pulmonary fibrosis (scarring of the lungs) or other lung or breathing problems, eye or vision problems, or liver disease.

  • tell your doctor if you are pregnant or plan to become pregnant. Gefitinib may cause infertility (difficulty becoming pregnant) in females. However, you should use birth control to prevent pregnancy during your treatment with gefitinib and for at least 2 weeks after you stop taking the medication. If you become pregnant while taking gefitinib, call your doctor. Gefitinib may harm the fetus and increase the risk of pregnancy loss.

  • tell your doctor if you are breastfeeding. You should not breast-feed while you are taking gefitinib.

Unless your doctor tells you otherwise, continue your normal diet.

Take the missed dose as soon as you remember it. However, if it is less than 12 hours before your next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

  • Gefitinib may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • dry skin

    • itching

    • rash

    • acne

    • mouth sores

    • weakness

  • Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately or get emergency medical treatment:

    • new or worsening shortness of breath, cough, or fever

    • severe or ongoing diarrhea

    • severe abdominal pain

    • loss of appetite

    • eye pain, redness, or irritation

    • vision changes

    • watery eyes

    • eye sensitivity to light

    • hives

    • blisters or peeling skin

    • swelling of the eyes, face, lips, tongue, throat, hands, arms, feet, ankles or lower legs

    • nausea

    • vomiting

    • yellowing of the skin or eyes

    • dark urine

    • pale stools

    • pain or discomfort in the right upper stomach area

  • Gefitinib may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your body's response to gefitinib.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug Interaction
Montelukast Montelukast The metabolism of Montelukast can be decreased when combined with Gefitinib.
Leflunomide Leflunomide Gefitinib may decrease the excretion rate of Leflunomide which could result in a higher serum level.
Delavirdine Delavirdine The metabolism of Gefitinib can be decreased when combined with Delavirdine.
Nevirapine Nevirapine The metabolism of Gefitinib can be decreased when combined with Nevirapine.
Atorvastatin Atorvastatin The metabolism of Atorvastatin can be decreased when combined with Gefitinib.
Dolasetron Dolasetron The metabolism of Dolasetron can be decreased when combined with Gefitinib.
Aminophylline Aminophylline The metabolism of Aminophylline can be decreased when combined with Gefitinib.
Calcium Carbonate Calcium Carbonate Calcium carbonate can cause a decrease in the absorption of Gefitinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Candesartan Candesartan The metabolism of Candesartan can be decreased when combined with Gefitinib.
Cilostazol Cilostazol The serum concentration of Cilostazol can be increased when it is combined with Gefitinib.
Clopidogrel Clopidogrel The metabolism of Clopidogrel can be decreased when combined with Gefitinib.
Erythromycin and Sulfisoxazole Erythromycin and Sulfisoxazole The metabolism of Gefitinib can be decreased when combined with Erythromycin.
Estrogen and Progestin (Oral Contraceptives) Estrogen and Progestin (Oral Contraceptives) Gefitinib may decrease the excretion rate of Conjugated estrogens which could result in a higher serum level.
Fenofibrate Fenofibrate The metabolism of Fenofibrate can be decreased when combined with Gefitinib.
Magnesium Hydroxide Magnesium Hydroxide Magnesium hydroxide can cause a decrease in the absorption of Gefitinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Magnesium Oxide Magnesium Oxide Magnesium oxide can cause a decrease in the absorption of Gefitinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Penbutolol Penbutolol The metabolism of Gefitinib can be decreased when combined with Acebutolol.
Ranitidine Ranitidine Ranitidine can cause a decrease in the absorption of Gefitinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Reserpine Reserpine The metabolism of Gefitinib can be increased when combined with Reserpine.
Sumatriptan Sumatriptan Gefitinib may decrease the excretion rate of Sumatriptan which could result in a higher serum level.
Tacrolimus Tacrolimus The serum concentration of Tacrolimus can be increased when it is combined with Gefitinib.
Triamcinolone Triamcinolone The metabolism of Gefitinib can be increased when combined with Triamcinolone.
Famotidine Injection Famotidine Injection Famotidine can cause a decrease in the absorption of Gefitinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Fluconazole Injection Fluconazole Injection The metabolism of Gefitinib can be decreased when combined with Fluconazole.
Hydromorphone Injection Hydromorphone Injection The metabolism of Hydromorphone can be decreased when combined with Gefitinib.
Meperidine Injection Meperidine Injection The metabolism of Meperidine can be decreased when combined with Gefitinib.
Metoclopramide Injection Metoclopramide Injection The metabolism of Gefitinib can be decreased when combined with Metoclopramide.
Metronidazole Injection Metronidazole Injection The metabolism of Metronidazole can be decreased when combined with Gefitinib.
Zidovudine Injection Zidovudine Injection Gefitinib may decrease the excretion rate of Zidovudine which could result in a higher serum level.
Altretamine Altretamine The metabolism of Amphetamine can be decreased when combined with Gefitinib.
Cyclosporine Cyclosporine The metabolism of Cyclosporine can be decreased when combined with Gefitinib.
Ondansetron Ondansetron The metabolism of Ondansetron can be decreased when combined with Gefitinib.
Torsemide Torsemide The metabolism of Torasemide can be decreased when combined with Gefitinib.
Olanzapine Olanzapine Olanzapine can cause a decrease in the absorption of Gefitinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Alosetron Alosetron The metabolism of Alosetron can be decreased when combined with Gefitinib.
Dofetilide Dofetilide The metabolism of Dofetilide can be decreased when combined with Gefitinib.
Entacapone Entacapone The metabolism of Gefitinib can be decreased when combined with Entacapone.
Hydroxychloroquine Hydroxychloroquine The metabolism of Gefitinib can be decreased when combined with Hydroxychloroquine.
Meloxicam Meloxicam The metabolism of Meloxicam can be decreased when combined with Gefitinib.
Oxcarbazepine Oxcarbazepine The metabolism of Gefitinib can be increased when combined with Oxcarbazepine.
Pantoprazole Pantoprazole Pantoprazole can cause a decrease in the absorption of Gefitinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Telmisartan Telmisartan Telmisartan may decrease the excretion rate of Gefitinib which could result in a higher serum level.
Zaleplon Zaleplon The metabolism of Zaleplon can be decreased when combined with Gefitinib.
Anakinra Anakinra The metabolism of Gefitinib can be increased when combined with Anakinra.
Trimipramine Trimipramine The metabolism of Trimipramine can be decreased when combined with Gefitinib.
Etanercept Injection Etanercept Injection The metabolism of Gefitinib can be increased when combined with Etanercept.
Modafinil Modafinil The metabolism of Gefitinib can be increased when combined with Modafinil.
Tenofovir Tenofovir The metabolism of Tenofovir can be decreased when combined with Gefitinib.
Sirolimus Sirolimus The metabolism of Sirolimus can be decreased when combined with Gefitinib.
Dutasteride Dutasteride The metabolism of Dutasteride can be decreased when combined with Gefitinib.
Eplerenone Eplerenone The metabolism of Eplerenone can be decreased when combined with Gefitinib.
Escitalopram Escitalopram The serum concentration of Escitalopram can be increased when it is combined with Gefitinib.
Zonisamide Zonisamide The metabolism of Zonisamide can be decreased when combined with Gefitinib.
Adalimumab Injection Adalimumab Injection The metabolism of Gefitinib can be increased when combined with Adalimumab.
Aripiprazole Aripiprazole The metabolism of Aripiprazole can be decreased when combined with Gefitinib.
Atomoxetine Atomoxetine The metabolism of Atomoxetine can be decreased when combined with Gefitinib.
Ezetimibe Ezetimibe Gefitinib may decrease the excretion rate of Ezetimibe which could result in a higher serum level.
Teriparatide Injection Teriparatide Injection The therapeutic efficacy of Teriparatide can be decreased when used in combination with Gefitinib.
Atazanavir Atazanavir The metabolism of Atazanavir can be decreased when combined with Gefitinib.
Almotriptan Almotriptan The metabolism of Almotriptan can be decreased when combined with Gefitinib.
Eletriptan Eletriptan The metabolism of Eletriptan can be decreased when combined with Gefitinib.
Mefloquine Mefloquine The metabolism of Gefitinib can be decreased when combined with Mefloquine.
Rosuvastatin Rosuvastatin Gefitinib may decrease the excretion rate of Rosuvastatin which could result in a higher serum level.
Vardenafil Vardenafil The metabolism of Vardenafil can be decreased when combined with Gefitinib.
Alfuzosin Alfuzosin The metabolism of Alfuzosin can be decreased when combined with Gefitinib.
Aprepitant Aprepitant The metabolism of Gefitinib can be decreased when combined with Aprepitant.
Tegaserod Tegaserod The metabolism of Gefitinib can be decreased when combined with Tegaserod.
Tadalafil Tadalafil The metabolism of Tadalafil can be decreased when combined with Gefitinib.
Progesterone Progesterone Progesterone may decrease the excretion rate of Gefitinib which could result in a higher serum level.
Apomorphine Injection Apomorphine Injection The metabolism of Apomorphine can be decreased when combined with Gefitinib.
Darbepoetin Alfa Injection Darbepoetin Alfa Injection The risk or severity of Thrombosis can be increased when Darbepoetin alfa is combined with Gefitinib.
Infliximab Injection Infliximab Injection The metabolism of Gefitinib can be increased when combined with Infliximab.
Protriptyline Protriptyline The metabolism of Protriptyline can be decreased when combined with Gefitinib.
Rifaximin Rifaximin The metabolism of Gefitinib can be increased when combined with Rifaximin.
Duloxetine Duloxetine The metabolism of Gefitinib can be decreased when combined with Duloxetine.
Norethindrone Norethindrone The metabolism of Norethisterone can be decreased when combined with Gefitinib.
Trospium Trospium The metabolism of Gefitinib can be decreased when combined with Trospium.
Bosentan Bosentan The metabolism of Bosentan can be decreased when combined with Gefitinib.
Cinacalcet Cinacalcet The metabolism of Gefitinib can be decreased when combined with Cinacalcet.
Erlotinib Erlotinib The metabolism of Gefitinib can be decreased when combined with Erlotinib.
Eszopiclone Eszopiclone The metabolism of Eszopiclone can be decreased when combined with Gefitinib.
Solifenacin Solifenacin The metabolism of Solifenacin can be decreased when combined with Gefitinib.
Voriconazole Voriconazole The metabolism of Gefitinib can be decreased when combined with Voriconazole.
Dextroamphetamine Dextroamphetamine The metabolism of Amphetamine can be decreased when combined with Gefitinib.
Peginterferon Alfa-2b (PEG-Intron) Peginterferon Alfa-2b (PEG-Intron) The metabolism of Gefitinib can be decreased when combined with Peginterferon alfa-2b.
Ramelteon Ramelteon The metabolism of Ramelteon can be decreased when combined with Gefitinib.
Darifenacin Darifenacin The metabolism of Darifenacin can be decreased when combined with Gefitinib.
Fentanyl Fentanyl The metabolism of Fentanyl can be decreased when combined with Gefitinib.
Tipranavir Tipranavir The metabolism of Tipranavir can be decreased when combined with Gefitinib.
Ranolazine Ranolazine The serum concentration of Ranolazine can be increased when it is combined with Gefitinib.
Abatacept Injection Abatacept Injection The metabolism of Gefitinib can be increased when combined with Abatacept.
Imatinib Imatinib The metabolism of Gefitinib can be decreased when combined with Imatinib.
Paliperidone Paliperidone The metabolism of Paliperidone can be decreased when combined with Gefitinib.
Bortezomib Bortezomib The metabolism of Bortezomib can be decreased when combined with Gefitinib.
Clofarabine Injection Clofarabine Injection Gefitinib may decrease the excretion rate of Clofarabine which could result in a higher serum level.
Oxaliplatin Injection Oxaliplatin Injection Gefitinib may decrease the excretion rate of Oxaliplatin which could result in a higher serum level.
Primaquine Primaquine The metabolism of Gefitinib can be decreased when combined with Primaquine.
Lisdexamfetamine Lisdexamfetamine The metabolism of Lisdexamfetamine can be decreased when combined with Gefitinib.
Retapamulin Retapamulin The metabolism of Retapamulin can be decreased when combined with Gefitinib.
Sorafenib Sorafenib The metabolism of Sorafenib can be decreased when combined with Gefitinib.
Sunitinib Sunitinib The metabolism of Gefitinib can be decreased when combined with Sunitinib.
Dronabinol Dronabinol Dronabinol may decrease the excretion rate of Gefitinib which could result in a higher serum level.
Lapatinib Lapatinib The metabolism of Lapatinib can be decreased when combined with Gefitinib.
Dasatinib Dasatinib The metabolism of Dasatinib can be decreased when combined with Gefitinib.
Mexiletine Mexiletine The metabolism of Mexiletine can be decreased when combined with Gefitinib.
Armodafinil Armodafinil The metabolism of Gefitinib can be increased when combined with Armodafinil.
Ivermectin Ivermectin Gefitinib may decrease the excretion rate of Ivermectin which could result in a higher serum level.
Temsirolimus Temsirolimus The metabolism of Temsirolimus can be decreased when combined with Gefitinib.
Nilotinib Nilotinib The metabolism of Gefitinib can be decreased when combined with Nilotinib.
Bexarotene Bexarotene The metabolism of Bexarotene can be decreased when combined with Gefitinib.
Budesonide Budesonide The metabolism of Gefitinib can be increased when combined with Budesonide.
Chloramphenicol Injection Chloramphenicol Injection The metabolism of Gefitinib can be decreased when combined with Chloramphenicol.
Etravirine Etravirine The metabolism of Etravirine can be decreased when combined with Gefitinib.
Mitoxantrone Injection Mitoxantrone Injection Gefitinib may decrease the excretion rate of Mitoxantrone which could result in a higher serum level.
Desvenlafaxine Desvenlafaxine The metabolism of Gefitinib can be decreased when combined with Desvenlafaxine.
Cevimeline Cevimeline The metabolism of Cevimeline can be decreased when combined with Gefitinib.
Nebivolol Nebivolol The metabolism of Nebivolol can be decreased when combined with Gefitinib.
Tretinoin Tretinoin The metabolism of Tretinoin can be decreased when combined with Gefitinib.
Flecainide Flecainide The metabolism of Flecainide can be decreased when combined with Gefitinib.
Certolizumab Injection Certolizumab Injection The metabolism of Gefitinib can be increased when combined with Certolizumab pegol.
Ixabepilone Injection Ixabepilone Injection The metabolism of Ixabepilone can be decreased when combined with Gefitinib.
Irinotecan Injection Irinotecan Injection The metabolism of Irinotecan can be decreased when combined with Gefitinib.
Praziquantel Praziquantel The metabolism of Praziquantel can be decreased when combined with Gefitinib.
Mitotane Mitotane The metabolism of Gefitinib can be increased when combined with Mitotane.
Rufinamide Rufinamide The metabolism of Rufinamide can be decreased when combined with Gefitinib.
Midazolam Midazolam The serum concentration of Midazolam can be increased when it is combined with Gefitinib.
Eltrombopag Eltrombopag Eltrombopag may decrease the excretion rate of Gefitinib which could result in a higher serum level.
Dexlansoprazole Dexlansoprazole Gefitinib can cause a decrease in the absorption of Dexlansoprazole resulting in a reduced serum concentration and potentially a decrease in efficacy.
Fesoterodine Fesoterodine The metabolism of Fesoterodine can be decreased when combined with Gefitinib.
Betaxolol Betaxolol The metabolism of Betaxolol can be decreased when combined with Gefitinib.
Iloperidone Iloperidone The metabolism of Iloperidone can be decreased when combined with Gefitinib.
Prasugrel Prasugrel The metabolism of Prasugrel can be decreased when combined with Gefitinib.
Lacosamide Lacosamide The metabolism of Lacosamide can be decreased when combined with Gefitinib.
Everolimus Everolimus The metabolism of Everolimus can be decreased when combined with Gefitinib.
Tolvaptan (low blood sodium) Tolvaptan (low blood sodium) The metabolism of Tolvaptan can be decreased when combined with Gefitinib.
Dronedarone Dronedarone The metabolism of Dronedarone can be decreased when combined with Gefitinib.
Pralatrexate Injection Pralatrexate Injection Gefitinib may decrease the excretion rate of Pralatrexate which could result in a higher serum level.
Palonosetron Injection Palonosetron Injection The metabolism of Palonosetron can be decreased when combined with Gefitinib.
Saxagliptin Saxagliptin The metabolism of Saxagliptin can be decreased when combined with Gefitinib.
Romidepsin Injection Romidepsin Injection The metabolism of Romidepsin can be decreased when combined with Gefitinib.
Tapentadol Tapentadol The metabolism of Tapentadol can be decreased when combined with Gefitinib.
Topotecan Topotecan Gefitinib may decrease the excretion rate of Topotecan which could result in a higher serum level.
Golimumab Injection Golimumab Injection The metabolism of Gefitinib can be increased when combined with Golimumab.
Pazopanib Pazopanib The metabolism of Pazopanib can be decreased when combined with Gefitinib.
Asenapine Asenapine Asenapine can cause a decrease in the absorption of Gefitinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Pitavastatin Pitavastatin Gefitinib may decrease the excretion rate of Pitavastatin which could result in a higher serum level.
Albendazole Albendazole The metabolism of Albendazole can be decreased when combined with Gefitinib.
Levonorgestrel Levonorgestrel The metabolism of Levonorgestrel can be decreased when combined with Gefitinib.
Oxymorphone Oxymorphone The metabolism of Oxymorphone can be decreased when combined with Gefitinib.
Tocilizumab Injection Tocilizumab Injection The metabolism of Gefitinib can be increased when combined with Tocilizumab.
Cabazitaxel Injection Cabazitaxel Injection The metabolism of Gefitinib can be decreased when combined with Cabazitaxel.
Acetaminophen Injection Acetaminophen Injection The serum concentration of Acetaminophen can be increased when it is combined with Gefitinib.
Vilazodone Vilazodone The metabolism of Gefitinib can be decreased when combined with Vilazodone.
Busulfan Injection Busulfan Injection The metabolism of Busulfan can be decreased when combined with Gefitinib.
Roflumilast Roflumilast The metabolism of Roflumilast can be decreased when combined with Gefitinib.
Linagliptin Linagliptin The metabolism of Linagliptin can be decreased when combined with Gefitinib.
Rilpivirine Rilpivirine Rilpivirine may decrease the excretion rate of Gefitinib which could result in a higher serum level.
Telaprevir Telaprevir Gefitinib may decrease the excretion rate of Glecaprevir which could result in a higher serum level.
Potassium Iodide Potassium Iodide The therapeutic efficacy of Potassium Iodide can be decreased when used in combination with Gefitinib.
Cyclophosphamide Injection Cyclophosphamide Injection The metabolism of Cyclophosphamide can be decreased when combined with Gefitinib.
Abiraterone Abiraterone The metabolism of Gefitinib can be decreased when combined with Abiraterone.
Rivaroxaban Rivaroxaban Gefitinib may decrease the excretion rate of Rivaroxaban which could result in a higher serum level.
Brentuximab Vedotin Injection Brentuximab Vedotin Injection The metabolism of Brentuximab vedotin can be decreased when combined with Gefitinib.
Ruxolitinib Ruxolitinib The metabolism of Ruxolitinib can be decreased when combined with Gefitinib.
Vandetanib Vandetanib The metabolism of Gefitinib can be decreased when combined with Vandetanib.
Clobazam Clobazam The metabolism of Clobazam can be decreased when combined with Gefitinib.
Vemurafenib Vemurafenib The metabolism of Vemurafenib can be decreased when combined with Gefitinib.
Vismodegib Vismodegib Vismodegib may decrease the excretion rate of Gefitinib which could result in a higher serum level.
Ivacaftor Ivacaftor The metabolism of Ivacaftor can be decreased when combined with Gefitinib.
Axitinib Axitinib The metabolism of Axitinib can be decreased when combined with Gefitinib.
Crizotinib Crizotinib The metabolism of Gefitinib can be decreased when combined with Crizotinib.
Cabergoline Cabergoline The metabolism of Cabergoline can be decreased when combined with Gefitinib.
Ambrisentan Ambrisentan The metabolism of Ambrisentan can be decreased when combined with Gefitinib.
Enzalutamide Enzalutamide The metabolism of Gefitinib can be increased when combined with Enzalutamide.
Mirabegron Mirabegron The metabolism of Mirabegron can be decreased when combined with Gefitinib.
Regorafenib Regorafenib The metabolism of Gefitinib can be decreased when combined with Regorafenib.
Bosutinib Bosutinib The metabolism of Bosutinib can be decreased when combined with Gefitinib.
Teriflunomide Teriflunomide Gefitinib may decrease the excretion rate of Teriflunomide which could result in a higher serum level.
Cabozantinib (thyroid cancer) Cabozantinib (thyroid cancer) The metabolism of Cabozantinib can be decreased when combined with Gefitinib.
Tofacitinib Tofacitinib The metabolism of Tofacitinib can be decreased when combined with Gefitinib.
Alogliptin Alogliptin The metabolism of Alogliptin can be decreased when combined with Gefitinib.
Ponatinib Ponatinib The metabolism of Ponatinib can be decreased when combined with Gefitinib.
Pomalidomide Pomalidomide The metabolism of Pomalidomide can be decreased when combined with Gefitinib.
Ado-trastuzumab Emtansine Injection Ado-trastuzumab Emtansine Injection The metabolism of Trastuzumab emtansine can be decreased when combined with Gefitinib.
Apixaban Apixaban Gefitinib may decrease the excretion rate of Apixaban which could result in a higher serum level.
Dabrafenib Dabrafenib The metabolism of Dabrafenib can be decreased when combined with Gefitinib.
Ospemifene Ospemifene The metabolism of Ospemifene can be decreased when combined with Gefitinib.
Dolutegravir Dolutegravir Gefitinib may decrease the excretion rate of Dolutegravir which could result in a higher serum level.
Afatinib Afatinib Gefitinib may decrease the excretion rate of Afatinib which could result in a higher serum level.
Levomilnacipran Levomilnacipran The metabolism of Levomilnacipran can be decreased when combined with Gefitinib.
Vortioxetine Vortioxetine The metabolism of Vortioxetine can be decreased when combined with Gefitinib.
Perampanel Perampanel The metabolism of Perampanel can be decreased when combined with Gefitinib.
Ibrutinib Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Gefitinib.
Lomitapide Lomitapide The metabolism of Lomitapide can be decreased when combined with Gefitinib.
Ketorolac Injection Ketorolac Injection The metabolism of Ketorolac can be decreased when combined with Gefitinib.
Simeprevir Simeprevir Gefitinib may decrease the excretion rate of Simeprevir which could result in a higher serum level.
Sofosbuvir Sofosbuvir Gefitinib may decrease the excretion rate of Sofosbuvir which could result in a higher serum level.
Dapagliflozin Dapagliflozin The metabolism of Dapagliflozin can be decreased when combined with Gefitinib.
Apremilast Apremilast The metabolism of Gefitinib can be increased when combined with Apremilast.
Ceritinib Ceritinib The metabolism of Ceritinib can be decreased when combined with Gefitinib.
Siltuximab Injection Siltuximab Injection The metabolism of Gefitinib can be increased when combined with Siltuximab.
Idelalisib Idelalisib The metabolism of Idelalisib can be decreased when combined with Gefitinib.
Testosterone Injection Testosterone Injection Gefitinib may decrease the excretion rate of Testosterone which could result in a higher serum level.
Oritavancin Injection Oritavancin Injection The metabolism of Gefitinib can be decreased when combined with Oritavancin.
Vorapaxar Vorapaxar The metabolism of Vorapaxar can be decreased when combined with Gefitinib.
Hydrocodone Hydrocodone The metabolism of Hydrocodone can be decreased when combined with Gefitinib.
Suvorexant Suvorexant The metabolism of Suvorexant can be decreased when combined with Gefitinib.
Olaparib Olaparib The metabolism of Gefitinib can be decreased when combined with Olaparib.
Methamphetamine Methamphetamine The metabolism of Metamfetamine can be decreased when combined with Gefitinib.
Tasimelteon Tasimelteon The metabolism of Tasimelteon can be decreased when combined with Gefitinib.
Riociguat Riociguat Gefitinib may decrease the excretion rate of Riociguat which could result in a higher serum level.
Nintedanib Nintedanib The metabolism of Nintedanib can be decreased when combined with Gefitinib.
Secukinumab Injection Secukinumab Injection The metabolism of Gefitinib can be increased when combined with Secukinumab.
Risperidone Injection Risperidone Injection The metabolism of Risperidone can be decreased when combined with Gefitinib.
Palbociclib Palbociclib The metabolism of Palbociclib can be decreased when combined with Gefitinib.
Lenvatinib Lenvatinib Gefitinib may decrease the excretion rate of Lenvatinib which could result in a higher serum level.
Naloxegol Naloxegol The metabolism of Gefitinib can be decreased when combined with Naloxegol.
Panobinostat Panobinostat The metabolism of Panobinostat can be decreased when combined with Gefitinib.
Haloperidol Injection Haloperidol Injection The serum concentration of Haloperidol can be increased when it is combined with Gefitinib.
Sonidegib Sonidegib The metabolism of Sonidegib can be decreased when combined with Gefitinib.
Rolapitant Rolapitant The metabolism of Gefitinib can be decreased when combined with Rolapitant.
Daclatasvir Daclatasvir Daclatasvir may decrease the excretion rate of Gefitinib which could result in a higher serum level.
Brexpiprazole Brexpiprazole The metabolism of Brexpiprazole can be decreased when combined with Gefitinib.
Ziprasidone Injection Ziprasidone Injection The metabolism of Ziprasidone can be decreased when combined with Gefitinib.
Cariprazine Cariprazine The metabolism of Cariprazine can be decreased when combined with Gefitinib.
Cobimetinib Cobimetinib The metabolism of Cobimetinib can be decreased when combined with Gefitinib.
Trabectedin Injection Trabectedin Injection The metabolism of Trabectedin can be decreased when combined with Gefitinib.
Osimertinib Osimertinib The metabolism of Osimertinib can be decreased when combined with Gefitinib.
Alectinib Alectinib The metabolism of Gefitinib can be decreased when combined with Alectinib.
Ixazomib Ixazomib The metabolism of Ixazomib can be decreased when combined with Gefitinib.
Lesinurad Lesinurad The metabolism of Lesinurad can be decreased when combined with Gefitinib.
Dexamethasone Injection Dexamethasone Injection The metabolism of Gefitinib can be increased when combined with Dexamethasone.
Brivaracetam Injection Brivaracetam Injection The metabolism of Brivaracetam can be decreased when combined with Gefitinib.
Venetoclax Venetoclax The metabolism of Venetoclax can be decreased when combined with Gefitinib.
Cobicistat Cobicistat The metabolism of Gefitinib can be decreased when combined with Cobicistat.
Diphenhydramine Injection Diphenhydramine Injection The metabolism of Diphenhydramine can be decreased when combined with Gefitinib.
Rucaparib Rucaparib The metabolism of Rucaparib can be decreased when combined with Gefitinib.
Ribociclib Ribociclib The metabolism of Ribociclib can be decreased when combined with Gefitinib.
Parathyroid Hormone Injection Parathyroid Hormone Injection The therapeutic efficacy of Parathyroid hormone can be decreased when used in combination with Gefitinib.
Brigatinib Brigatinib The metabolism of Brigatinib can be decreased when combined with Gefitinib.
Doxepin (Insomnia) Doxepin (Insomnia) Doxepin can cause a decrease in the absorption of Gefitinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Deutetrabenazine Deutetrabenazine The metabolism of Deutetrabenazine can be decreased when combined with Gefitinib.
Valbenazine Valbenazine The metabolism of Valbenazine can be decreased when combined with Gefitinib.
Deflazacort Deflazacort The metabolism of Gefitinib can be increased when combined with Deflazacort.
Safinamide Safinamide Safinamide may decrease the excretion rate of Gefitinib which could result in a higher serum level.
Midostaurin Midostaurin The metabolism of Gefitinib can be increased when combined with Midostaurin.
Neratinib Neratinib The metabolism of Neratinib can be decreased when combined with Gefitinib.
Abaloparatide Injection Abaloparatide Injection The therapeutic efficacy of Abaloparatide can be decreased when used in combination with Gefitinib.
Enasidenib Enasidenib The metabolism of Enasidenib can be decreased when combined with Gefitinib.
Aprepitant/Fosaprepitant Injection Aprepitant/Fosaprepitant Injection The metabolism of Fosaprepitant can be decreased when combined with Gefitinib.
Copanlisib Injection Copanlisib Injection The metabolism of Copanlisib can be decreased when combined with Gefitinib.
Delafloxacin Delafloxacin Gefitinib may decrease the excretion rate of Delafloxacin which could result in a higher serum level.
Abemaciclib Abemaciclib The metabolism of Abemaciclib can be decreased when combined with Gefitinib.
Acalabrutinib Acalabrutinib The metabolism of Gefitinib can be decreased when combined with Acalabrutinib.
Letermovir Letermovir Letermovir may decrease the excretion rate of Gefitinib which could result in a higher serum level.
Tetrabenazine Tetrabenazine The metabolism of Tetrabenazine can be decreased when combined with Gefitinib.
Ertugliflozin Ertugliflozin Gefitinib may decrease the excretion rate of Ertugliflozin which could result in a higher serum level.
Buprenorphine Injection Buprenorphine Injection Buprenorphine may decrease the excretion rate of Gefitinib which could result in a higher serum level.
Apalutamide Apalutamide The metabolism of Gefitinib can be increased when combined with Apalutamide.
Fostamatinib Fostamatinib Fostamatinib may decrease the excretion rate of Gefitinib which could result in a higher serum level.
Avatrombopag Avatrombopag Avatrombopag may decrease the excretion rate of Gefitinib which could result in a higher serum level.
Baricitinib Baricitinib The metabolism of Gefitinib can be decreased when combined with Baricitinib.
Sodium Zirconium Cyclosilicate Sodium Zirconium Cyclosilicate Sodium zirconium cyclosilicate can cause a decrease in the absorption of Gefitinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Lofexidine Lofexidine The metabolism of Lofexidine can be decreased when combined with Gefitinib.
Eliglustat Eliglustat The metabolism of Eliglustat can be decreased when combined with Gefitinib.
Encorafenib Encorafenib The metabolism of Encorafenib can be decreased when combined with Gefitinib.
Ivosidenib Ivosidenib The metabolism of Ivosidenib can be decreased when combined with Gefitinib.
Lusutrombopag Lusutrombopag Gefitinib may decrease the excretion rate of Lusutrombopag which could result in a higher serum level.
Elagolix Elagolix The metabolism of Elagolix can be decreased when combined with Gefitinib.
Doravirine Doravirine The metabolism of Doravirine can be decreased when combined with Gefitinib.
Tafenoquine Tafenoquine The metabolism of Tafenoquine can be decreased when combined with Gefitinib.
Cannabidiol Cannabidiol Cannabidiol may decrease the excretion rate of Gefitinib which could result in a higher serum level.
Dacomitinib Dacomitinib The metabolism of Gefitinib can be decreased when combined with Dacomitinib.
Duvelisib Duvelisib Gefitinib may decrease the excretion rate of Duvelisib which could result in a higher serum level.
Stiripentol Stiripentol The metabolism of Gefitinib can be decreased when combined with Stiripentol.
Talazoparib Talazoparib Gefitinib may decrease the excretion rate of Talazoparib which could result in a higher serum level.
Gilteritinib Gilteritinib Gilteritinib may decrease the excretion rate of Gefitinib which could result in a higher serum level.
Glasdegib Glasdegib Gefitinib may decrease the excretion rate of Glasdegib which could result in a higher serum level.
Lorlatinib Lorlatinib The metabolism of Lorlatinib can be decreased when combined with Gefitinib.
Methoxy Polyethylene Glycol-Epoetin Beta Injection Methoxy Polyethylene Glycol-Epoetin Beta Injection The risk or severity of Thrombosis can be increased when Methoxy polyethylene glycol-epoetin beta is combined with Gefitinib.
Paclitaxel (with albumin) Injection Paclitaxel (with albumin) Injection The metabolism of Paclitaxel can be decreased when combined with Gefitinib.
Rifamycin Rifamycin The metabolism of Gefitinib can be increased when combined with Rifamycin.
Prucalopride Prucalopride The metabolism of Prucalopride can be decreased when combined with Gefitinib.
Emapalumab-lzsg Injection Emapalumab-lzsg Injection The metabolism of Gefitinib can be increased when combined with Emapalumab.
Siponimod Siponimod The metabolism of Siponimod can be decreased when combined with Gefitinib.
Erdafitinib Erdafitinib The metabolism of Erdafitinib can be decreased when combined with Gefitinib.
Esomeprazole Injection Esomeprazole Injection Gefitinib can cause a decrease in the absorption of Esomeprazole resulting in a reduced serum concentration and potentially a decrease in efficacy.
Alpelisib Alpelisib The serum concentration of Alpelisib can be increased when it is combined with Gefitinib.
Cladribine Cladribine Gefitinib may decrease the excretion rate of Cladribine which could result in a higher serum level.
Darolutamide Darolutamide The serum concentration of Darolutamide can be increased when it is combined with Gefitinib.
Triclabendazole Triclabendazole The metabolism of Triclabendazole can be decreased when combined with Gefitinib.
Entrectinib Entrectinib The metabolism of Entrectinib can be decreased when combined with Gefitinib.
Pexidartinib Pexidartinib The metabolism of Pexidartinib can be decreased when combined with Gefitinib.
Istradefylline Istradefylline The metabolism of Istradefylline can be decreased when combined with Gefitinib.
Pitolisant Pitolisant The serum concentration of Gefitinib can be decreased when it is combined with Pitolisant.
Fedratinib Fedratinib Fedratinib may decrease the excretion rate of Gefitinib which could result in a higher serum level.
Lefamulin Lefamulin The metabolism of Lefamulin can be decreased when combined with Gefitinib.
Phenytoin Injection Phenytoin Injection The metabolism of Gefitinib can be increased when combined with Phenytoin.
Fosphenytoin Injection Fosphenytoin Injection The metabolism of Gefitinib can be increased when combined with Fosphenytoin.
Zanubrutinib Zanubrutinib The metabolism of Zanubrutinib can be decreased when combined with Gefitinib.
Voxelotor Voxelotor The serum concentration of Voxelotor can be increased when it is combined with Gefitinib.
Avapritinib Avapritinib The metabolism of Avapritinib can be decreased when combined with Gefitinib.
Lasmiditan Lasmiditan The serum concentration of Gefitinib can be increased when it is combined with Lasmiditan.
Ubrogepant Ubrogepant The serum concentration of Ubrogepant can be increased when it is combined with Gefitinib.
Tazemetostat Tazemetostat Gefitinib may decrease the excretion rate of Tazemetostat which could result in a higher serum level.
Cenobamate Cenobamate The serum concentration of Gefitinib can be decreased when it is combined with Cenobamate.
Ozanimod Ozanimod Gefitinib may decrease the excretion rate of Ozanimod which could result in a higher serum level.
Selumetinib Selumetinib Gefitinib may decrease the excretion rate of Selumetinib which could result in a higher serum level.
Rimegepant Rimegepant The serum concentration of Rimegepant can be increased when it is combined with Gefitinib.
Tucatinib Tucatinib The metabolism of Tucatinib can be decreased when combined with Gefitinib.
Ripretinib Ripretinib Gefitinib may decrease the excretion rate of Ripretinib which could result in a higher serum level.
Capmatinib Capmatinib The serum concentration of Gefitinib can be increased when it is combined with Capmatinib.
Lemborexant Lemborexant The metabolism of Lemborexant can be decreased when combined with Gefitinib.
Fenfluramine Fenfluramine The metabolism of Gefitinib can be decreased when combined with Fenfluramine.
Fostemsavir Fostemsavir Gefitinib may decrease the excretion rate of Fostemsavir which could result in a higher serum level.
Pralsetinib Pralsetinib Gefitinib may decrease the excretion rate of Pralsetinib which could result in a higher serum level.
Satralizumab-mwge Injection Satralizumab-mwge Injection The serum concentration of Gefitinib can be decreased when it is combined with Satralizumab.
Progestin-Only (drospirenone) Oral Contraceptives Progestin-Only (drospirenone) Oral Contraceptives The metabolism of Drospirenone can be decreased when combined with Gefitinib.
Theophylline Theophylline The metabolism of Theophylline can be decreased when combined with Gefitinib.
Indomethacin Indomethacin The metabolism of Indomethacin can be decreased when combined with Gefitinib.
Mefenamic Acid Mefenamic Acid The metabolism of Mefenamic acid can be decreased when combined with Gefitinib.
Naproxen Naproxen The metabolism of Naproxen can be decreased when combined with Gefitinib.
Trazodone Trazodone The metabolism of Trazodone can be decreased when combined with Gefitinib.
Sodium Bicarbonate Sodium Bicarbonate Sodium bicarbonate can cause a decrease in the absorption of Gefitinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Hydroxyurea Hydroxyurea The metabolism of Gefitinib can be decreased when combined with Hydroxyurea.
Phenobarbital Phenobarbital The metabolism of Gefitinib can be increased when combined with Phenobarbital.
Methotrexate Injection Methotrexate Injection The metabolism of Methotrexate can be decreased when combined with Gefitinib.
Primidone Primidone The metabolism of Gefitinib can be increased when combined with Primidone.
Methsuximide Methsuximide The metabolism of Methsuximide can be decreased when combined with Gefitinib.
Chlorpromazine Chlorpromazine The metabolism of Chlorpromazine can be decreased when combined with Gefitinib.
Diazepam Diazepam The metabolism of Diazepam can be decreased when combined with Gefitinib.
Lorazepam Lorazepam The metabolism of Lorazepam can be decreased when combined with Gefitinib.
Codeine Codeine The metabolism of Codeine can be decreased when combined with Gefitinib.
Tranylcypromine Tranylcypromine The metabolism of Gefitinib can be decreased when combined with Tranylcypromine.
Phenelzine Phenelzine The metabolism of Gefitinib can be decreased when combined with Phenelzine.
Prochlorperazine Prochlorperazine The metabolism of Prochlorperazine can be decreased when combined with Gefitinib.
Thioridazine Thioridazine The metabolism of Gefitinib can be decreased when combined with Thioridazine.
Dapsone Dapsone The metabolism of Gefitinib can be decreased when combined with Dapsone.
Oxycodone Oxycodone The metabolism of Oxycodone can be decreased when combined with Gefitinib.
Methadone Methadone The metabolism of Methadone can be decreased when combined with Gefitinib.
Oxybutynin Oxybutynin The metabolism of Oxybutynin can be decreased when combined with Gefitinib.
Benztropine Benztropine The metabolism of Benzatropine can be decreased when combined with Gefitinib.
Maprotiline Maprotiline The metabolism of Maprotiline can be decreased when combined with Gefitinib.
Ibuprofen Ibuprofen The metabolism of Ibuprofen can be decreased when combined with Gefitinib.
Orphenadrine Orphenadrine The metabolism of Gefitinib can be decreased when combined with Orphenadrine.
Perphenazine Perphenazine The metabolism of Perphenazine can be decreased when combined with Gefitinib.
Fluphenazine Fluphenazine The metabolism of Gefitinib can be decreased when combined with Fluphenazine.
Phentermine Phentermine The metabolism of Phentermine can be decreased when combined with Gefitinib.
Amoxapine Amoxapine The metabolism of Gefitinib can be decreased when combined with Amoxapine.
Sulfasalazine Sulfasalazine Gefitinib may decrease the excretion rate of Sulfasalazine which could result in a higher serum level.
Hydrocortisone Hydrocortisone The metabolism of Hydrocortisone can be decreased when combined with Gefitinib.
Doxorubicin Doxorubicin The metabolism of Doxorubicin can be decreased when combined with Gefitinib.
Dactinomycin Dactinomycin Gefitinib may decrease the excretion rate of Dactinomycin which could result in a higher serum level.
Carbamazepine Carbamazepine The metabolism of Gefitinib can be increased when combined with Carbamazepine.
Clonidine Clonidine The metabolism of Clonidine can be decreased when combined with Gefitinib.
Prazosin Prazosin Gefitinib may decrease the excretion rate of Prazosin which could result in a higher serum level.
Cimetidine Cimetidine Cimetidine can cause a decrease in the absorption of Gefitinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Warfarin Warfarin Gefitinib may increase the anticoagulant activities of Warfarin.
Loperamide Loperamide The metabolism of Loperamide can be decreased when combined with Gefitinib.
Promethazine Promethazine Promethazine can cause a decrease in the absorption of Gefitinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Daunorubicin Daunorubicin Gefitinib may decrease the excretion rate of Daunorubicin which could result in a higher serum level.
Nitrofurantoin Nitrofurantoin Gefitinib may decrease the excretion rate of Nitrofurantoin which could result in a higher serum level.
Chloroquine Chloroquine The metabolism of Chloroquine can be decreased when combined with Gefitinib.
Quinine Quinine The metabolism of Quinine can be decreased when combined with Gefitinib.
Clindamycin Injection Clindamycin Injection The metabolism of Clindamycin can be decreased when combined with Gefitinib.
Desipramine Desipramine The metabolism of Desipramine can be decreased when combined with Gefitinib.
Amitriptyline Amitriptyline The metabolism of Amitriptyline can be decreased when combined with Gefitinib.
Imipramine Imipramine The metabolism of Imipramine can be decreased when combined with Gefitinib.
Quinidine Quinidine The metabolism of Quinidine can be decreased when combined with Gefitinib.
Procainamide Procainamide The metabolism of Procainamide can be decreased when combined with Gefitinib.
Rifampin Rifampin The metabolism of Gefitinib can be increased when combined with Rifampicin.
Valproic Acid Valproic Acid The metabolism of Valproic acid can be decreased when combined with Gefitinib.
Tamoxifen Tamoxifen The metabolism of Tamoxifen can be decreased when combined with Gefitinib.
Levothyroxine Levothyroxine The therapeutic efficacy of Levothyroxine can be decreased when used in combination with Gefitinib.
Liothyronine Liothyronine The therapeutic efficacy of Liothyronine can be decreased when used in combination with Gefitinib.
Methimazole Methimazole The therapeutic efficacy of Gefitinib can be decreased when used in combination with Methimazole.
Propylthiouracil Propylthiouracil The therapeutic efficacy of Propylthiouracil can be decreased when used in combination with Gefitinib.
Chlorpropamide Chlorpropamide The metabolism of Chlorpropamide can be decreased when combined with Gefitinib.
Tolbutamide Tolbutamide The metabolism of Tolbutamide can be decreased when combined with Gefitinib.
Tolazamide Tolazamide The metabolism of Tolazamide can be decreased when combined with Gefitinib.
Dextromethorphan Dextromethorphan The metabolism of Dextromethorphan can be decreased when combined with Gefitinib.
Niacin Niacin The metabolism of Gefitinib can be decreased when combined with Niacin.
Clemastine Clemastine The metabolism of Gefitinib can be decreased when combined with Clemastine.
Chlorpheniramine Chlorpheniramine The metabolism of Chlorpheniramine can be decreased when combined with Gefitinib.
Meclizine Meclizine The metabolism of Meclizine can be decreased when combined with Gefitinib.
Chlorzoxazone Chlorzoxazone The metabolism of Chlorzoxazone can be decreased when combined with Gefitinib.
Carisoprodol Carisoprodol The metabolism of Carisoprodol can be decreased when combined with Gefitinib.
Folic Acid Folic Acid Gefitinib may decrease the excretion rate of Folic acid which could result in a higher serum level.
Disulfiram Disulfiram The metabolism of Disulfiram can be decreased when combined with Gefitinib.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) The serum concentration of Propranolol can be increased when it is combined with Gefitinib.
Nortriptyline Nortriptyline The metabolism of Nortriptyline can be decreased when combined with Gefitinib.
Nadolol Nadolol The metabolism of Nadolol can be decreased when combined with Gefitinib.
Allopurinol Allopurinol Gefitinib may decrease the excretion rate of Allopurinol which could result in a higher serum level.
Fluorouracil Injection Fluorouracil Injection Gefitinib may decrease the excretion rate of Fluorouracil which could result in a higher serum level.
Colchicine Colchicine The metabolism of Colchicine can be decreased when combined with Gefitinib.
Cephalexin Cephalexin The metabolism of Cephalexin can be decreased when combined with Gefitinib.
Calcitonin Salmon Injection Calcitonin Salmon Injection The therapeutic efficacy of Salmon calcitonin can be decreased when used in combination with Gefitinib.
Ketoconazole Ketoconazole The metabolism of Gefitinib can be decreased when combined with Ketoconazole.
Thiotepa Injection Thiotepa Injection The metabolism of Thiotepa can be decreased when combined with Gefitinib.
Vincristine Injection Vincristine Injection The metabolism of Vincristine can be decreased when combined with Gefitinib.
Vinblastine Vinblastine The metabolism of Gefitinib can be decreased when combined with Vinblastine.
Metoprolol Metoprolol The metabolism of Metoprolol can be decreased when combined with Gefitinib.
Hydroxyzine Hydroxyzine The metabolism of Gefitinib can be decreased when combined with Hydroxyzine.
Aspirin Aspirin The metabolism of Acetylsalicylic acid can be decreased when combined with Gefitinib.
Alprazolam Alprazolam The metabolism of Alprazolam can be decreased when combined with Gefitinib.
Triazolam Triazolam The metabolism of Triazolam can be decreased when combined with Gefitinib.
Trimethoprim Trimethoprim The metabolism of Trimethoprim can be decreased when combined with Gefitinib.
Diltiazem Diltiazem The metabolism of Diltiazem can be decreased when combined with Gefitinib.
Nifedipine Nifedipine The metabolism of Gefitinib can be decreased when combined with Nifedipine.
Timolol Timolol The metabolism of Timolol can be decreased when combined with Gefitinib.
Verapamil Verapamil The metabolism of Verapamil can be decreased when combined with Gefitinib.
Atenolol Atenolol The metabolism of Atenolol can be decreased when combined with Gefitinib.
Pindolol Pindolol The metabolism of Pindolol can be decreased when combined with Gefitinib.
Piroxicam Piroxicam The metabolism of Piroxicam can be decreased when combined with Gefitinib.
Etoposide Etoposide The metabolism of Etoposide can be decreased when combined with Gefitinib.
Glyburide Glyburide Gefitinib may decrease the excretion rate of Glyburide which could result in a higher serum level.
Glipizide Glipizide The metabolism of Glipizide can be decreased when combined with Gefitinib.
Pentamidine Injection Pentamidine Injection The metabolism of Pentamidine can be decreased when combined with Gefitinib.
Labetalol Labetalol The metabolism of Gefitinib can be decreased when combined with Labetalol.
Pimozide Pimozide The metabolism of Pimozide can be decreased when combined with Gefitinib.
Flurbiprofen Flurbiprofen The metabolism of Flurbiprofen can be decreased when combined with Gefitinib.
Amiodarone Amiodarone The metabolism of Amiodarone can be decreased when combined with Gefitinib.
Buspirone Buspirone The metabolism of Buspirone can be decreased when combined with Gefitinib.
Lovastatin Lovastatin The metabolism of Lovastatin can be decreased when combined with Gefitinib.
Ciprofloxacin Ciprofloxacin The metabolism of Gefitinib can be decreased when combined with Ciprofloxacin.
Diclofenac Diclofenac The metabolism of Diclofenac can be decreased when combined with Gefitinib.
Fluoxetine Fluoxetine The serum concentration of Gefitinib can be increased when it is combined with Fluoxetine.
Clozapine Clozapine The metabolism of Clozapine can be decreased when combined with Gefitinib.
Idarubicin Idarubicin The metabolism of Idarubicin can be decreased when combined with Gefitinib.
Clarithromycin Clarithromycin The metabolism of Clarithromycin can be decreased when combined with Gefitinib.
Etodolac Etodolac The metabolism of Etodolac can be decreased when combined with Gefitinib.
Felodipine Felodipine The metabolism of Felodipine can be decreased when combined with Gefitinib.
Nabumetone Nabumetone The metabolism of Nabumetone can be decreased when combined with Gefitinib.
Pravastatin Pravastatin Pravastatin may decrease the excretion rate of Gefitinib which could result in a higher serum level.
Simvastatin Simvastatin The metabolism of Simvastatin can be decreased when combined with Gefitinib.
Epoetin Alfa, Injection Epoetin Alfa, Injection The risk or severity of Thrombosis can be increased when Erythropoietin is combined with Gefitinib.
Teniposide Injection Teniposide Injection The metabolism of Teniposide can be decreased when combined with Gefitinib.
Itraconazole Itraconazole The metabolism of Itraconazole can be decreased when combined with Gefitinib.
Sotalol Sotalol The metabolism of Sotalol can be decreased when combined with Gefitinib.
Zolpidem Zolpidem The metabolism of Zolpidem can be decreased when combined with Gefitinib.
Doxazosin Doxazosin The metabolism of Doxazosin can be decreased when combined with Gefitinib.
Omeprazole Omeprazole Omeprazole can cause a decrease in the absorption of Gefitinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Cisapride Cisapride The metabolism of Gefitinib can be decreased when combined with Cisapride.
Fluvastatin Fluvastatin The metabolism of Fluvastatin can be decreased when combined with Gefitinib.
Venlafaxine Venlafaxine The metabolism of Gefitinib can be decreased when combined with Venlafaxine.
Nizatidine Nizatidine Nizatidine can cause a decrease in the absorption of Gefitinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Famciclovir Famciclovir The metabolism of Famciclovir can be decreased when combined with Gefitinib.
Fluvoxamine Fluvoxamine The metabolism of Gefitinib can be decreased when combined with Fluvoxamine.
Nefazodone Nefazodone The metabolism of Nefazodone can be decreased when combined with Gefitinib.
Losartan Losartan The metabolism of Losartan can be decreased when combined with Gefitinib.
Tramadol Tramadol The metabolism of Tramadol can be decreased when combined with Gefitinib.
Vinorelbine Injection Vinorelbine Injection Gefitinib may increase the neutropenic activities of Vinorelbine.
Lansoprazole Lansoprazole Lansoprazole can cause a decrease in the absorption of Gefitinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ifosfamide Injection Ifosfamide Injection The metabolism of Ifosfamide can be decreased when combined with Gefitinib.
Nicardipine Nicardipine The metabolism of Nicardipine can be decreased when combined with Gefitinib.
Bupropion Bupropion The metabolism of Gefitinib can be decreased when combined with Bupropion.
Ticlopidine Ticlopidine The metabolism of Ticlopidine can be decreased when combined with Gefitinib.
Saquinavir Saquinavir The metabolism of Gefitinib can be decreased when combined with Saquinavir.
Nisoldipine Nisoldipine The metabolism of Nisoldipine can be decreased when combined with Gefitinib.
Lamivudine Lamivudine Gefitinib may decrease the excretion rate of Lamivudine which could result in a higher serum level.
Riluzole Riluzole Gefitinib may decrease the excretion rate of Riluzole which could result in a higher serum level.
Glimepiride Glimepiride The metabolism of Glimepiride can be decreased when combined with Gefitinib.
Indinavir Indinavir The metabolism of Gefitinib can be decreased when combined with Indinavir.
Ritonavir Ritonavir The serum concentration of Gefitinib can be increased when it is combined with Ritonavir.
Docetaxel Injection Docetaxel Injection The metabolism of Docetaxel can be decreased when combined with Gefitinib.
Clomipramine Clomipramine The metabolism of Clomipramine can be decreased when combined with Gefitinib.
Zafirlukast Zafirlukast The metabolism of Zafirlukast can be decreased when combined with Gefitinib.
Mirtazapine Mirtazapine The metabolism of Mirtazapine can be decreased when combined with Gefitinib.
Zileuton Zileuton The metabolism of Zileuton can be decreased when combined with Gefitinib.
Valsartan Valsartan The metabolism of Valsartan can be decreased when combined with Gefitinib.
Donepezil Donepezil The metabolism of Donepezil can be decreased when combined with Gefitinib.
Nelfinavir Nelfinavir The metabolism of Nelfinavir can be decreased when combined with Gefitinib.
Azithromycin Azithromycin The metabolism of Azithromycin can be decreased when combined with Gefitinib.
Carvedilol Carvedilol The metabolism of Carvedilol can be decreased when combined with Gefitinib.
Flutamide Flutamide The metabolism of Flutamide can be decreased when combined with Gefitinib.
Selegiline Selegiline The metabolism of Selegiline can be decreased when combined with Gefitinib.
Bicalutamide Bicalutamide The metabolism of Gefitinib can be decreased when combined with Bicalutamide.
Sertraline Sertraline The metabolism of Sertraline can be decreased when combined with Gefitinib.
Propafenone Propafenone The metabolism of Gefitinib can be decreased when combined with Propafenone.
Raloxifene Raloxifene Gefitinib may decrease the excretion rate of Raloxifene which could result in a higher serum level.
Irbesartan Irbesartan The metabolism of Irbesartan can be decreased when combined with Gefitinib.
Tamsulosin Tamsulosin The metabolism of Tamsulosin can be decreased when combined with Gefitinib.
Finasteride Finasteride The metabolism of Finasteride can be decreased when combined with Gefitinib.
Quetiapine Quetiapine The metabolism of Quetiapine can be decreased when combined with Gefitinib.
Paroxetine Paroxetine The metabolism of Gefitinib can be decreased when combined with Paroxetine.
Citalopram Citalopram Gefitinib may increase the QTc-prolonging activities of Citalopram.
Capecitabine Capecitabine The metabolism of Capecitabine can be decreased when combined with Gefitinib.
Efavirenz Efavirenz The metabolism of Gefitinib can be increased when combined with Efavirenz.
Sildenafil Sildenafil The metabolism of Sildenafil can be decreased when combined with Gefitinib.
Celecoxib Celecoxib The metabolism of Celecoxib can be decreased when combined with Gefitinib.
Rosiglitazone Rosiglitazone The metabolism of Rosiglitazone can be decreased when combined with Gefitinib.
Tolterodine Tolterodine The metabolism of Tolterodine can be decreased when combined with Gefitinib.
Thalidomide Thalidomide The metabolism of Thalidomide can be decreased when combined with Gefitinib.
Aluminum Hydroxide Aluminum Hydroxide Aluminum hydroxide can cause a decrease in the absorption of Gefitinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Nateglinide Nateglinide The metabolism of Nateglinide can be decreased when combined with Gefitinib.
Galantamine Galantamine The metabolism of Galantamine can be decreased when combined with Gefitinib.
Rabeprazole Rabeprazole Rabeprazole can cause a decrease in the absorption of Gefitinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Terbinafine Terbinafine The metabolism of Gefitinib can be decreased when combined with Terbinafine.

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