Indinavir

Indinavir is used along with other medications to treat human immunodeficiency virus (HIV) infection. Indinavir is in a class of medications called protease inhibitors. It works by decreasing the amount of HIV in the blood. Although indinavir does not cure HIV, it may decrease your chance of developing acquired immunodeficiency syndrome (AIDS) and HIV-related illnesses such as serious infections or cancer. Taking these medications along with practicing safer sex and making other lifestyle changes may decrease the risk of transmitting the HIV virus to other people.

Indinavir comes as a capsule to take by mouth. It is usually taken every 8 hours (three times a day). Take indinavir at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take indinavir exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Take indinavir on an empty stomach, 1 hour before meals or 2 hours after meals, with water, skim or nonfat milk, juice, coffee, or tea. However, if indinavir upsets your stomach, it may be taken with a light meal, such as dry toast or cornflakes with skim or nonfat milk. Talk to your doctor or pharmacist about what foods may be taken with indinavir.

Do not crush or chew the capsule, but it may be opened and mixed with fruit puree (such as banana).

Continue to take indinavir even if you feel well. Do not stop taking indinavir without talking to your doctor.

Your doctor may need to interrupt your treatment if you experience certain side effects. Be sure to tell your doctor how you are feeling during your treatment with indinavir.

Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

Indinavir is also used sometimes in combination with other medications to treat healthcare workers and other individuals exposed to HIV infection after accidental contact with HIV-contaminated blood, tissues, or other body fluids. Talk to your doctor about the possible risks of using this drug for your condition.

Before taking indinavir,

• tell your doctor and pharmacist if you are allergic to indinavir, any other medications, or any of the ingredients in indinavir capsules. Ask your pharmacist for a list of the ingredients.

• tell your doctor if you are taking any of the following medications: alfuzosin (Uroxatral); alprazolam (Xanax); amiodarone (Nexterone, Pacerone); cisapride (Propulsid) (not available in the U.S.); ergot-type medications such as dihydroergotamine (D.H.E. 45, Migranal), ergonovine (Ergotrate), ergotamine (Ergomar, in Cafergot, in Migergot), and methylergonovine (Methergine); lovastatin (Altoprev, Mevacor); lurasidone (Latuda); midazolam (Versed) by mouth; pimozide (Orap); sildenafil (only Revatio brand used for lung disease); simvastatin (Zocor, in Vytorin); or triazolam (Halcion). Your doctor will probably tell you not to take indinavir.

• tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, and nutritional supplements you are taking or plan to take. Be sure to mention any of the following: bosentan (Tracleer); calcium-channel blockers such as amlodipine (Norvasc, in Amturnide, in Tekamlo), felodipine, nicardipine, and nifedipine (Adalat, Afeditab, Procardia); carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, others); cholesterol-lowering medications (statins) such as atorvastatin (Lipitor, in Caduet) and rosuvastatin (Crestor); clarithromycin (Biaxin, in PrevPac); colchicine (Colcrys, Mitigare, in Col-Probenecid); dexamethasone; fluconazole (Diflucan); fluticasone (Flonase, Flovent, in Advair, in Dymista); itraconazole (Onmel, Sporanox); ketoconazole (Extina, Nizoral, Xolegel); other medications for HIV including atazanavir (Reyataz, in Evotaz), delavirdine (Rescriptor), efavirenz (Sustiva, in Atripla), nelfinavir (Viracept), nevirapine (Viramune), ritonavir (Norvir, in Kaletra, in Viekira Pak), and saquinavir (Invirase); medications for irregular heartbeat such as lidocaine (Glydo, Xylocaine) and quinidine (in Nuedexta); medications that suppress the immune system such as cyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune), and tacrolimus (Astagraf XL, Envarsus XR, Prograf); midazolam (Versed) by injection; certain phosphodiesterase inhibitors (PDE-5 inhibitors) used for erectile dysfunction such as sildenafil (Viagra), tadalafil (Adcirca, Cialis), and vardenafil (Levitra, in Staxyn); phenobarbital; phenytoin (Dilantin, Phenytek); quetiapine (Seroquel); rifabutin (Mycobutin); rifampin (Rifadin, Rimactane, in Rifamate, in Rifater); salmeterol (Serevent, in Advair); trazodone; and venlafaxine (Effexor). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with indinavir, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.

• tell your doctor what herbal products you are taking, especially St. John's wort.

• if you are taking didanosine (Videx), take it at least one hour before or after indinavir.

• tell your doctor if you have or have ever had hemophilia (bleeding disorder in which the blood does not clot properly), diabetes, or kidney or liver disease.

• tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking indinavir, call your doctor. You should not breastfeed if you are infected with HIV or if you are taking indinavir.

• you should know that your body fat may increase or move to different areas of your body such as your breasts, upper back, neck, chest, and stomach area. Loss of fat from the legs, arms, and face can also happen.

• you should know that you may experience hyperglycemia (increases in your blood sugar) while you are taking this medication, even if you do not already have diabetes. Tell your doctor immediately if you have any of the following symptoms while you are taking indinavir: extreme thirst, frequent urination, extreme hunger, blurred vision, or weakness. It is very important to call your doctor as soon as you have any of these symptoms, because high blood sugar that is not treated can cause a serious condition called ketoacidosis. Ketoacidosis may become life-threatening if it is not treated at an early stage. Symptoms of ketoacidosis include dry mouth, nausea and vomiting, shortness of breath, breath that smells fruity, and decreased consciousness.

• you should know that while you are taking medications to treat HIV infection, your immune system may get stronger and begin to fight other infections that were already in your body. This may cause you to develop symptoms of those infections. If you have new or worsening symptoms at any time during your treatment with indinavir, be sure to tell your doctor.

Drink at least 48 ounces (1.5 liters), which is approximately six 8-ounce (240-milliliter) glasses, of water or other liquids every 24 hours.

Talk to your doctor about eating grapefruit and drinking grapefruit juice while taking this medication.

If you miss a dose by less than 2 hours, take the missed dose as soon as you remember it. However, if you miss a dose by more than 2 hours, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

• Indinavir may cause side effects. Tell your doctor if this symptom is severe or does not go away:

  • change in sense of taste

• Indinavir may cause side effects. Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately or get emergency medical treatment:

  • rash

  • hives

  • itching

  • peeling or blistering skin

  • back pain

  • pain in the side of your body

  • middle to lower stomach pain

  • blood in urine

  • muscle pain or weakness

  • nausea

  • excessive tiredness

  • unusual bleeding or bruising

  • loss of appetite

  • pain in the upper right part of your stomach

  • flu-like symptoms

  • dark yellow or brown urine

  • yellowing of the skin or eyes

  • shortness of breath

  • fast heartbeat

  • confusion

  • dizziness

  • headache

  • paleness

• Indinavir may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

• If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. A desiccant (drying agent) is included with your capsules; keep this in your medicine bottle at all times. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Symptoms of overdose may include the following:

• pain in the side of your body

• blood in urine

• nausea

• vomiting

• diarrhea

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to indinavir.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

• IDV

Drug	Interaction
Repaglinide	Repaglinide Repaglinide may decrease the excretion rate of Indinavir which could result in a higher serum level.
Montelukast	Montelukast The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Indinavir is combined with Montelukast.
Insulin Glargine (rDNA origin) Injection	Insulin Glargine (rDNA origin) Injection The therapeutic efficacy of Insulin glargine can be decreased when used in combination with Indinavir.
Leflunomide	Leflunomide The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Indinavir is combined with Leflunomide.
Delavirdine	Delavirdine The serum concentration of Indinavir can be increased when it is combined with Delavirdine.
Nevirapine	Nevirapine The serum concentration of Indinavir can be decreased when it is combined with Nevirapine.
Atorvastatin	Atorvastatin The metabolism of Atorvastatin can be decreased when combined with Indinavir.
Alendronate	Alendronate The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Indinavir is combined with Alendronic acid.
Calcium Carbonate	Calcium Carbonate Calcium carbonate can cause a decrease in the absorption of Indinavir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Cilostazol	Cilostazol The metabolism of Cilostazol can be decreased when combined with Indinavir.
Clopidogrel	Clopidogrel The metabolism of Clopidogrel can be decreased when combined with Indinavir.
Erythromycin and Sulfisoxazole	Erythromycin and Sulfisoxazole The metabolism of Indinavir can be decreased when combined with Erythromycin.
Estrogen and Progestin (Oral Contraceptives)	Estrogen and Progestin (Oral Contraceptives) The excretion of Conjugated estrogens can be decreased when combined with Indinavir.
Fenofibrate	Fenofibrate Indinavir may decrease the excretion rate of Fenofibrate which could result in a higher serum level.
Guanfacine	Guanfacine The risk or severity of adverse effects can be increased when Indinavir is combined with Guanfacine.
Magnesium Hydroxide	Magnesium Hydroxide Magnesium hydroxide can cause a decrease in the absorption of Indinavir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Magnesium Oxide	Magnesium Oxide Magnesium oxide can cause a decrease in the absorption of Indinavir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Miglitol	Miglitol The therapeutic efficacy of Miglitol can be decreased when used in combination with Indinavir.
Mycophenolate	Mycophenolate The metabolism of Mycophenolic acid can be decreased when combined with Indinavir.
Nafarelin	Nafarelin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Indinavir is combined with Nafarelin.
Paregoric	Paregoric The metabolism of Morphine can be decreased when combined with Indinavir.
Ranitidine	Ranitidine Ranitidine can cause a decrease in the absorption of Indinavir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Reserpine	Reserpine Reserpine may decrease the excretion rate of Indinavir which could result in a higher serum level.
Sumatriptan	Sumatriptan The excretion of Sumatriptan can be decreased when combined with Indinavir.
Tacrolimus	Tacrolimus The serum concentration of Tacrolimus can be increased when it is combined with Indinavir.
Triamcinolone	Triamcinolone The metabolism of Triamcinolone can be increased when combined with Indinavir.
Famotidine Injection	Famotidine Injection Famotidine can cause a decrease in the absorption of Indinavir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Fluconazole Injection	Fluconazole Injection The metabolism of Indinavir can be decreased when combined with Fluconazole.
Metoclopramide Injection	Metoclopramide Injection The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Indinavir is combined with Metoclopramide.
Metronidazole Injection	Metronidazole Injection The metabolism of Metronidazole can be decreased when combined with Indinavir.
Morphine Injection	Morphine Injection The metabolism of Morphine can be decreased when combined with Indinavir.
Pamidronate Injection	Pamidronate Injection The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Indinavir is combined with Pamidronic acid.
Zidovudine Injection	Zidovudine Injection The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Indinavir is combined with Zidovudine.
Cyclosporine	Cyclosporine The metabolism of Cyclosporine can be decreased when combined with Indinavir.
Ondansetron	Ondansetron The metabolism of Ondansetron can be decreased when combined with Indinavir.
Torsemide	Torsemide The excretion of Torasemide can be decreased when combined with Indinavir.
Olanzapine	Olanzapine Olanzapine can cause a decrease in the absorption of Indinavir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Eprosartan	Eprosartan The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Indinavir is combined with Eprosartan.
Oxcarbazepine	Oxcarbazepine The metabolism of Indinavir can be increased when combined with Oxcarbazepine.
Pantoprazole	Pantoprazole Pantoprazole can cause a decrease in the absorption of Indinavir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Risedronate	Risedronate The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Indinavir is combined with Risedronic acid.
Telmisartan	Telmisartan Indinavir may decrease the excretion rate of Telmisartan which could result in a higher serum level.
Zaleplon	Zaleplon The metabolism of Zaleplon can be decreased when combined with Indinavir.
Anakinra	Anakinra The metabolism of Indinavir can be increased when combined with Anakinra.
Etanercept Injection	Etanercept Injection The metabolism of Indinavir can be increased when combined with Etanercept.
Modafinil	Modafinil The metabolism of Indinavir can be increased when combined with Modafinil.
Sirolimus	Sirolimus The metabolism of Sirolimus can be decreased when combined with Indinavir.
Dutasteride	Dutasteride The metabolism of Dutasteride can be decreased when combined with Indinavir.
Epinephrine Injection	Epinephrine Injection The risk or severity of adverse effects can be increased when Indinavir is combined with Epinephrine.
Eplerenone	Eplerenone The metabolism of Eplerenone can be decreased when combined with Indinavir.
Olmesartan	Olmesartan Olmesartan may decrease the excretion rate of Indinavir which could result in a higher serum level.
Zonisamide	Zonisamide The metabolism of Zonisamide can be decreased when combined with Indinavir.
Adalimumab Injection	Adalimumab Injection The metabolism of Indinavir can be increased when combined with Adalimumab.
Aripiprazole	Aripiprazole The metabolism of Aripiprazole can be decreased when combined with Indinavir.
Ezetimibe	Ezetimibe Indinavir may decrease the excretion rate of Ezetimibe which could result in a higher serum level.
Atazanavir	Atazanavir The risk or severity of hyperbilirubinemia can be increased when Atazanavir is combined with Indinavir.
Mefloquine	Mefloquine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Indinavir is combined with Mefloquine.
Rosuvastatin	Rosuvastatin Indinavir may decrease the excretion rate of Rosuvastatin which could result in a higher serum level.
Vardenafil	Vardenafil The serum concentration of Vardenafil can be increased when it is combined with Indinavir.
Alfuzosin	Alfuzosin The metabolism of Alfuzosin can be decreased when combined with Indinavir.
Aprepitant	Aprepitant The metabolism of Indinavir can be decreased when combined with Aprepitant.
Tadalafil	Tadalafil The metabolism of Tadalafil can be decreased when combined with Indinavir.
Progesterone	Progesterone Indinavir may decrease the excretion rate of Progesterone which could result in a higher serum level.
Apomorphine Injection	Apomorphine Injection The metabolism of Apomorphine can be decreased when combined with Indinavir.
Infliximab Injection	Infliximab Injection The metabolism of Indinavir can be increased when combined with Infliximab.
Norethindrone	Norethindrone The metabolism of Norethisterone can be decreased when combined with Indinavir.
Tinidazole	Tinidazole Indinavir may decrease the excretion rate of Tinidazole which could result in a higher serum level.
Bosentan	Bosentan The serum concentration of Bosentan can be increased when it is combined with Indinavir.
Erlotinib	Erlotinib The metabolism of Erlotinib can be decreased when combined with Indinavir.
Eszopiclone	Eszopiclone The metabolism of Eszopiclone can be decreased when combined with Indinavir.
Ganciclovir	Ganciclovir The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Indinavir is combined with Ganciclovir.
Insulin Aspart (rDNA Origin) Injection	Insulin Aspart (rDNA Origin) Injection The therapeutic efficacy of Insulin aspart can be decreased when used in combination with Indinavir.
Voriconazole	Voriconazole The metabolism of Indinavir can be decreased when combined with Voriconazole.
Pramlintide Injection	Pramlintide Injection The therapeutic efficacy of Pramlintide can be decreased when used in combination with Indinavir.
Exenatide Injection	Exenatide Injection The therapeutic efficacy of Exenatide can be decreased when used in combination with Indinavir.
Ibandronate	Ibandronate The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Indinavir is combined with Ibandronate.
Fentanyl	Fentanyl The metabolism of Fentanyl can be decreased when combined with Indinavir.
Deferasirox	Deferasirox The metabolism of Deferasirox can be decreased when combined with Indinavir.
Tipranavir	Tipranavir Tipranavir may decrease the excretion rate of Indinavir which could result in a higher serum level.
Insulin Detemir (rDNA Origin) Injection	Insulin Detemir (rDNA Origin) Injection The therapeutic efficacy of Insulin detemir can be decreased when used in combination with Indinavir.
Ranolazine	Ranolazine Indinavir may decrease the excretion rate of Ranolazine which could result in a higher serum level.
Abatacept Injection	Abatacept Injection The metabolism of Indinavir can be increased when combined with Abatacept.
Imatinib	Imatinib The metabolism of Indinavir can be decreased when combined with Imatinib.
Sitagliptin	Sitagliptin The therapeutic efficacy of Sitagliptin can be decreased when used in combination with Indinavir.
Gefitinib	Gefitinib The metabolism of Gefitinib can be decreased when combined with Indinavir.
Paliperidone	Paliperidone The metabolism of Paliperidone can be decreased when combined with Indinavir.
Influenza Vaccine, Live Intranasal	Influenza Vaccine, Live Intranasal The therapeutic efficacy of Typhoid Vaccine Live can be decreased when used in combination with Indinavir.
Live Shingles (Zoster) Vaccine (ZVL)	Live Shingles (Zoster) Vaccine (ZVL) The therapeutic efficacy of Varicella Zoster Vaccine (Live/attenuated) can be decreased when used in combination with Indinavir.
Fulvestrant Injection	Fulvestrant Injection The metabolism of Fulvestrant can be decreased when combined with Indinavir.
Insulin Glulisine (rDNA origin) Injection	Insulin Glulisine (rDNA origin) Injection The therapeutic efficacy of Insulin glulisine can be decreased when used in combination with Indinavir.
Darunavir	Darunavir The serum concentration of Darunavir can be increased when it is combined with Indinavir.
Retapamulin	Retapamulin The metabolism of Retapamulin can be decreased when combined with Indinavir.
Sorafenib	Sorafenib The metabolism of Sorafenib can be decreased when combined with Indinavir.
Sunitinib	Sunitinib The metabolism of Sunitinib can be decreased when combined with Indinavir.
Lapatinib	Lapatinib The metabolism of Lapatinib can be decreased when combined with Indinavir.
Dasatinib	Dasatinib The metabolism of Dasatinib can be decreased when combined with Indinavir.
Armodafinil	Armodafinil The metabolism of Indinavir can be increased when combined with Armodafinil.
Ivermectin	Ivermectin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Indinavir is combined with Ivermectin.
Temsirolimus	Temsirolimus The metabolism of Temsirolimus can be decreased when combined with Indinavir.
Raltegravir	Raltegravir The metabolism of Raltegravir can be decreased when combined with Indinavir.
Budesonide	Budesonide The metabolism of Indinavir can be increased when combined with Budesonide.
Chloramphenicol Injection	Chloramphenicol Injection The metabolism of Indinavir can be decreased when combined with Chloramphenicol.
Tretinoin	Tretinoin The metabolism of Tretinoin can be decreased when combined with Indinavir.
Certolizumab Injection	Certolizumab Injection The metabolism of Indinavir can be increased when combined with Certolizumab pegol.
Irinotecan Injection	Irinotecan Injection The risk or severity of neutropenia can be increased when Irinotecan is combined with Indinavir.
Daptomycin Injection	Daptomycin Injection The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Daptomycin is combined with Indinavir.
Praziquantel	Praziquantel The metabolism of Praziquantel can be decreased when combined with Indinavir.
Midazolam	Midazolam The serum concentration of Midazolam can be increased when it is combined with Indinavir.
Naltrexone Injection	Naltrexone Injection The metabolism of Naltrexone can be decreased when combined with Indinavir.
Eltrombopag	Eltrombopag The metabolism of Eltrombopag can be decreased when combined with Indinavir.
Dexlansoprazole	Dexlansoprazole Dexlansoprazole can cause a decrease in the absorption of Indinavir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Iloperidone	Iloperidone The metabolism of Iloperidone can be decreased when combined with Indinavir.
Dronedarone	Dronedarone The metabolism of Indinavir can be decreased when combined with Dronedarone.
Saxagliptin	Saxagliptin The therapeutic efficacy of Saxagliptin can be decreased when used in combination with Indinavir.
Romidepsin Injection	Romidepsin Injection The metabolism of Romidepsin can be decreased when combined with Indinavir.
Golimumab Injection	Golimumab Injection The metabolism of Indinavir can be increased when combined with Golimumab.
Asenapine	Asenapine Asenapine can cause a decrease in the absorption of Indinavir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Pitavastatin	Pitavastatin The serum concentration of Pitavastatin can be decreased when it is combined with Indinavir.
Levonorgestrel	Levonorgestrel The metabolism of Levonorgestrel can be decreased when combined with Indinavir.
Liraglutide Injection	Liraglutide Injection The therapeutic efficacy of Liraglutide can be decreased when used in combination with Indinavir.
Tocilizumab Injection	Tocilizumab Injection The metabolism of Indinavir can be increased when combined with Tocilizumab.
Cabazitaxel Injection	Cabazitaxel Injection The metabolism of Cabazitaxel can be decreased when combined with Indinavir.
Acetaminophen Injection	Acetaminophen Injection The metabolism of Acetaminophen can be decreased when combined with Indinavir.
Linagliptin	Linagliptin The therapeutic efficacy of Linagliptin can be decreased when used in combination with Indinavir.
Rilpivirine	Rilpivirine The serum concentration of Rilpivirine can be increased when it is combined with Indinavir.
Telaprevir	Telaprevir The excretion of Glecaprevir can be decreased when combined with Indinavir.
Cyclophosphamide Injection	Cyclophosphamide Injection The serum concentration of the active metabolites of Cyclophosphamide can be increased when Cyclophosphamide is used in combination with Indinavir.
Rivaroxaban	Rivaroxaban The metabolism of Rivaroxaban can be decreased when combined with Indinavir.
Ivacaftor	Ivacaftor The metabolism of Ivacaftor can be decreased when combined with Indinavir.
Axitinib	Axitinib The metabolism of Axitinib can be decreased when combined with Indinavir.
Crizotinib	Crizotinib The metabolism of Indinavir can be decreased when combined with Crizotinib.
Naloxone Injection	Naloxone Injection The metabolism of Naloxone can be decreased when combined with Indinavir.
Ambrisentan	Ambrisentan The excretion of Ambrisentan can be decreased when combined with Indinavir.
Ezogabine	Ezogabine The metabolism of Tiagabine can be decreased when combined with Indinavir.
Iloprost	Iloprost The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Indinavir is combined with Iloprost.
Enzalutamide	Enzalutamide The metabolism of Enzalutamide can be decreased when combined with Indinavir.
Lorcaserin	Lorcaserin The therapeutic efficacy of Mecasermin can be decreased when used in combination with Indinavir.
Tofacitinib	Tofacitinib The metabolism of Tofacitinib can be decreased when combined with Indinavir.
Alogliptin	Alogliptin The therapeutic efficacy of Alogliptin can be decreased when used in combination with Indinavir.
Ponatinib	Ponatinib The metabolism of Ponatinib can be decreased when combined with Indinavir.
Ado-trastuzumab Emtansine Injection	Ado-trastuzumab Emtansine Injection The metabolism of Trastuzumab emtansine can be decreased when combined with Indinavir.
Apixaban	Apixaban The metabolism of Apixaban can be decreased when combined with Indinavir.
Canagliflozin	Canagliflozin The therapeutic efficacy of Canagliflozin can be decreased when used in combination with Indinavir.
Dolutegravir	Dolutegravir The metabolism of Dolutegravir can be decreased when combined with Indinavir.
Vortioxetine	Vortioxetine The metabolism of Vortioxetine can be decreased when combined with Indinavir.
Perampanel	Perampanel The metabolism of Perampanel can be decreased when combined with Indinavir.
Ibrutinib	Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Indinavir.
Simeprevir	Simeprevir Simeprevir may decrease the excretion rate of Indinavir which could result in a higher serum level.
Dapagliflozin	Dapagliflozin The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Indinavir.
Apremilast	Apremilast The metabolism of Indinavir can be increased when combined with Apremilast.
Siltuximab Injection	Siltuximab Injection The metabolism of Indinavir can be increased when combined with Siltuximab.
Albiglutide Injection	Albiglutide Injection The therapeutic efficacy of Albiglutide can be decreased when used in combination with Indinavir.
Eslicarbazepine	Eslicarbazepine The metabolism of Eslicarbazepine can be decreased when combined with Indinavir.
Belinostat Injection	Belinostat Injection The metabolism of Belinostat can be decreased when combined with Indinavir.
Testosterone Injection	Testosterone Injection The metabolism of Testosterone can be decreased when combined with Indinavir.
Empagliflozin	Empagliflozin The therapeutic efficacy of Empagliflozin can be decreased when used in combination with Indinavir.
Dulaglutide Injection	Dulaglutide Injection The therapeutic efficacy of Dulaglutide can be decreased when used in combination with Indinavir.
Olaparib	Olaparib The metabolism of Olaparib can be decreased when combined with Indinavir.
Caspofungin Injection	Caspofungin Injection The excretion of Caspofungin can be decreased when combined with Indinavir.
Nintedanib	Nintedanib The metabolism of Nintedanib can be decreased when combined with Indinavir.
Secukinumab Injection	Secukinumab Injection The metabolism of Indinavir can be increased when combined with Secukinumab.
Risperidone Injection	Risperidone Injection The metabolism of Risperidone can be decreased when combined with Indinavir.
Insulin Human Inhalation	Insulin Human Inhalation The therapeutic efficacy of Insulin human can be decreased when used in combination with Indinavir.
Lenvatinib	Lenvatinib Lenvatinib may decrease the excretion rate of Indinavir which could result in a higher serum level.
Haloperidol Injection	Haloperidol Injection The serum concentration of Indinavir can be increased when it is combined with Haloperidol.
Deoxycholic Acid Injection	Deoxycholic Acid Injection Deoxycholic acid may increase the excretion rate of Indinavir which could result in a lower serum level and potentially a reduction in efficacy.
Daclatasvir	Daclatasvir The metabolism of Daclatasvir can be decreased when combined with Indinavir.
Ziprasidone Injection	Ziprasidone Injection The metabolism of Ziprasidone can be decreased when combined with Indinavir.
Eluxadoline	Eluxadoline The serum concentration of Eluxadoline can be increased when it is combined with Indinavir.
Insulin Degludec (rDNA Origin) Injection	Insulin Degludec (rDNA Origin) Injection The therapeutic efficacy of Insulin degludec can be decreased when used in combination with Indinavir.
Cobimetinib	Cobimetinib The excretion of Cobimetinib can be decreased when combined with Indinavir.
Trabectedin Injection	Trabectedin Injection The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Indinavir is combined with Trabectedin.
Amphotericin B Liposomal Injection	Amphotericin B Liposomal Injection The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Indinavir is combined with Amphotericin B.
Dexamethasone Injection	Dexamethasone Injection The metabolism of Dexamethasone can be increased when combined with Indinavir.
Cobicistat	Cobicistat The metabolism of Indinavir can be decreased when combined with Cobicistat.
Selexipag	Selexipag The excretion of Selexipag can be decreased when combined with Indinavir.
Furosemide Injection	Furosemide Injection The metabolism of Furosemide can be decreased when combined with Indinavir.
Rucaparib	Rucaparib The metabolism of Indinavir can be decreased when combined with Rucaparib.
Lixisenatide Injection	Lixisenatide Injection The therapeutic efficacy of Lixisenatide can be decreased when used in combination with Indinavir.
Doxepin (Insomnia)	Doxepin (Insomnia) Doxepin can cause a decrease in the absorption of Indinavir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Deutetrabenazine	Deutetrabenazine The metabolism of Deutetrabenazine can be decreased when combined with Indinavir.
Valbenazine	Valbenazine The metabolism of Valbenazine can be decreased when combined with Indinavir.
Deflazacort	Deflazacort The metabolism of Indinavir can be increased when combined with Deflazacort.
Safinamide	Safinamide The metabolism of Indinavir can be decreased when combined with Safinamide.
Midostaurin	Midostaurin The metabolism of Indinavir can be increased when combined with Midostaurin.
Enasidenib	Enasidenib The metabolism of Enasidenib can be decreased when combined with Indinavir.
Copanlisib Injection	Copanlisib Injection The metabolism of Copanlisib can be decreased when combined with Indinavir.
Delafloxacin	Delafloxacin The metabolism of Delafloxacin can be decreased when combined with Indinavir.
Acalabrutinib	Acalabrutinib The metabolism of Indinavir can be decreased when combined with Acalabrutinib.
Letermovir	Letermovir The metabolism of Letermovir can be decreased when combined with Indinavir.
Semaglutide Injection	Semaglutide Injection The therapeutic efficacy of Semaglutide can be decreased when used in combination with Indinavir.
Ertugliflozin	Ertugliflozin The therapeutic efficacy of Ertugliflozin can be decreased when used in combination with Indinavir.
Buprenorphine Injection	Buprenorphine Injection The metabolism of Buprenorphine can be decreased when combined with Indinavir.
Penicillamine	Penicillamine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Indinavir is combined with Penicillamine.
Sodium Zirconium Cyclosilicate	Sodium Zirconium Cyclosilicate Sodium zirconium cyclosilicate can cause a decrease in the absorption of Indinavir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Eliglustat	Eliglustat The metabolism of Eliglustat can be decreased when combined with Indinavir.
Binimetinib	Binimetinib The metabolism of Binimetinib can be decreased when combined with Indinavir.
Elagolix	Elagolix The metabolism of Elagolix can be decreased when combined with Indinavir.
Doravirine	Doravirine The metabolism of Doravirine can be decreased when combined with Indinavir.
Cannabidiol	Cannabidiol The metabolism of Indinavir can be decreased when combined with Cannabidiol.
Lorlatinib	Lorlatinib The metabolism of Lorlatinib can be decreased when combined with Indinavir.
Paclitaxel (with albumin) Injection	Paclitaxel (with albumin) Injection The metabolism of Paclitaxel can be decreased when combined with Indinavir.
Prucalopride	Prucalopride The metabolism of Indinavir can be decreased when combined with Prucalopride.
Emapalumab-lzsg Injection	Emapalumab-lzsg Injection The metabolism of Indinavir can be increased when combined with Emapalumab.
Acyclovir Ophthalmic	Acyclovir Ophthalmic The risk or severity of adverse effects can be increased when Indinavir is combined with Acyclovir.
Esomeprazole Injection	Esomeprazole Injection Esomeprazole can cause a decrease in the absorption of Indinavir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Cladribine	Cladribine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Indinavir is combined with Cladribine.
Darolutamide	Darolutamide The metabolism of Darolutamide can be decreased when combined with Indinavir.
Istradefylline	Istradefylline The metabolism of Istradefylline can be decreased when combined with Indinavir.
Pitolisant	Pitolisant The serum concentration of Pitolisant can be decreased when it is combined with Indinavir.
Phenytoin Injection	Phenytoin Injection The serum concentration of Phenytoin can be decreased when it is combined with Indinavir.
Fosphenytoin Injection	Fosphenytoin Injection The serum concentration of Indinavir can be decreased when it is combined with Fosphenytoin.
Voxelotor	Voxelotor The serum concentration of Voxelotor can be increased when it is combined with Indinavir.
Lumateperone	Lumateperone The serum concentration of Lumateperone can be increased when it is combined with Indinavir.
Cenobamate	Cenobamate The serum concentration of Indinavir can be decreased when it is combined with Cenobamate.
Selumetinib	Selumetinib The metabolism of Selumetinib can be decreased when combined with Indinavir.
Tucatinib	Tucatinib The metabolism of Tucatinib can be decreased when combined with Indinavir.
Remdesivir Injection	Remdesivir Injection The excretion of Remdesivir can be decreased when combined with Indinavir.
Sacituzumab govitecan-hziy Injection	Sacituzumab govitecan-hziy Injection The serum concentration of Sacituzumab govitecan can be increased when it is combined with Indinavir.
Selpercatinib	Selpercatinib The serum concentration of Selpercatinib can be increased when it is combined with Indinavir.
Capmatinib	Capmatinib The serum concentration of Capmatinib can be increased when it is combined with Indinavir.
Lemborexant	Lemborexant The serum concentration of Lemborexant can be increased when it is combined with Indinavir.
Belantamab Mafodotin-blmf Injection	Belantamab Mafodotin-blmf Injection Indinavir may decrease the excretion rate of Belantamab mafodotin which could result in a higher serum level.
Pralsetinib	Pralsetinib Pralsetinib may decrease the excretion rate of Indinavir which could result in a higher serum level.
Satralizumab-mwge Injection	Satralizumab-mwge Injection The serum concentration of Indinavir can be decreased when it is combined with Satralizumab.
Indomethacin	Indomethacin The metabolism of Indomethacin can be decreased when combined with Indinavir.
Naproxen	Naproxen The metabolism of Naproxen can be decreased when combined with Indinavir.
Trazodone	Trazodone The metabolism of Trazodone can be decreased when combined with Indinavir.
Isotretinoin	Isotretinoin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Indinavir is combined with Isotretinoin.
Sodium Bicarbonate	Sodium Bicarbonate Sodium bicarbonate can cause a decrease in the absorption of Indinavir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Phenobarbital	Phenobarbital The metabolism of Indinavir can be increased when combined with Phenobarbital.
Methotrexate Injection	Methotrexate Injection The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Indinavir is combined with Methotrexate.
Chlorpromazine	Chlorpromazine Chlorpromazine may decrease the excretion rate of Indinavir which could result in a higher serum level.
Diazepam	Diazepam The metabolism of Diazepam can be decreased when combined with Indinavir.
Amantadine	Amantadine The risk or severity of adverse effects can be increased when Indinavir is combined with Amantadine.
Codeine	Codeine The risk or severity of adverse effects can be increased when Indinavir is combined with Codeine.
Bromocriptine	Bromocriptine The therapeutic efficacy of Bromocriptine can be decreased when used in combination with Indinavir.
Phenelzine	Phenelzine The metabolism of Indinavir can be decreased when combined with Phenelzine.
Procarbazine	Procarbazine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Indinavir is combined with Procarbazine.
Minocycline	Minocycline The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Indinavir is combined with Minocycline.
Dapsone	Dapsone The metabolism of Dapsone can be decreased when combined with Indinavir.
Sulfadiazine	Sulfadiazine The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Indinavir.
Oxycodone	Oxycodone The metabolism of Oxycodone can be decreased when combined with Indinavir.
Methadone	Methadone The metabolism of Methadone can be decreased when combined with Indinavir.
Oxybutynin	Oxybutynin The metabolism of Oxybutynin can be decreased when combined with Indinavir.
Ibuprofen	Ibuprofen The metabolism of Ibuprofen can be decreased when combined with Indinavir.
Hydrocortisone	Hydrocortisone The metabolism of Hydrocortisone can be decreased when combined with Indinavir.
Doxorubicin	Doxorubicin Indinavir may decrease the excretion rate of Doxorubicin which could result in a higher serum level.
Cytarabine	Cytarabine The risk or severity of adverse effects can be increased when Indinavir is combined with Cytarabine.
Carbamazepine	Carbamazepine The serum concentration of Carbamazepine can be decreased when it is combined with Indinavir.
Methyldopa	Methyldopa The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Indinavir is combined with Methyldopa.
Clonidine	Clonidine The metabolism of Clonidine can be decreased when combined with Indinavir.
Prazosin	Prazosin The risk or severity of adverse effects can be increased when Indinavir is combined with Prazosin.
Cimetidine	Cimetidine Cimetidine can cause a decrease in the absorption of Indinavir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Warfarin	Warfarin The serum concentration of Warfarin can be increased when it is combined with Indinavir.
Promethazine	Promethazine Promethazine can cause a decrease in the absorption of Indinavir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Daunorubicin	Daunorubicin Daunorubicin may decrease the excretion rate of Indinavir which could result in a higher serum level.
Nitrofurantoin	Nitrofurantoin Indinavir may decrease the excretion rate of Nitrofurantoin which could result in a higher serum level.
Digoxin	Digoxin Indinavir may decrease the excretion rate of Digoxin which could result in a higher serum level.
Chloroquine	Chloroquine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Indinavir is combined with Chloroquine.
Quinine	Quinine The therapeutic efficacy of Quinine can be decreased when used in combination with Indinavir.
Sulfinpyrazone	Sulfinpyrazone Indinavir may decrease the excretion rate of Sulfinpyrazone which could result in a higher serum level.
Clindamycin Injection	Clindamycin Injection The metabolism of Clindamycin can be decreased when combined with Indinavir.
Amitriptyline	Amitriptyline The metabolism of Amitriptyline can be decreased when combined with Indinavir.
Imipramine	Imipramine The metabolism of Imipramine can be decreased when combined with Indinavir.
Quinidine	Quinidine The metabolism of Quinidine can be decreased when combined with Indinavir.
Procainamide	Procainamide The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Indinavir is combined with Procainamide.
Isoniazid	Isoniazid The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Indinavir is combined with Isoniazid.
Rifampin	Rifampin The metabolism of Indinavir can be increased when combined with Rifampicin.
Disopyramide	Disopyramide The therapeutic efficacy of Disopyramide can be decreased when used in combination with Indinavir.
Valproic Acid	Valproic Acid The metabolism of Valproic acid can be decreased when combined with Indinavir.
Tamoxifen	Tamoxifen The metabolism of Tamoxifen can be decreased when combined with Indinavir.
Levothyroxine	Levothyroxine The metabolism of Levothyroxine can be decreased when combined with Indinavir.
Liothyronine	Liothyronine The metabolism of Liothyronine can be decreased when combined with Indinavir.
Propylthiouracil	Propylthiouracil The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Indinavir is combined with Propylthiouracil.
Chlorpropamide	Chlorpropamide The therapeutic efficacy of Chlorpropamide can be decreased when used in combination with Indinavir.
Tolbutamide	Tolbutamide The therapeutic efficacy of Tolbutamide can be decreased when used in combination with Indinavir.
Tolazamide	Tolazamide The therapeutic efficacy of Tolazamide can be decreased when used in combination with Indinavir.
Dextromethorphan	Dextromethorphan The metabolism of Dextromethorphan can be decreased when combined with Indinavir.
Dinoprostone	Dinoprostone The excretion of Dinoprostone can be decreased when combined with Indinavir.
Niacin	Niacin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Indinavir is combined with Niacin.
Baclofen	Baclofen The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Indinavir.
Chlorpheniramine	Chlorpheniramine The metabolism of Chlorpheniramine can be decreased when combined with Indinavir.
Disulfiram	Disulfiram Indinavir may decrease the excretion rate of Disulfiram which could result in a higher serum level.
Propranolol (Cardiovascular)	Propranolol (Cardiovascular) The metabolism of Propranolol can be decreased when combined with Indinavir.
Minoxidil	Minoxidil The metabolism of Minoxidil can be decreased when combined with Indinavir.
Spironolactone	Spironolactone Indinavir may decrease the excretion rate of Spironolactone which could result in a higher serum level.
Amphotericin B Injection	Amphotericin B Injection The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Indinavir is combined with Amphotericin B.
Colchicine	Colchicine The serum concentration of Colchicine can be increased when it is combined with Indinavir.
Cefaclor	Cefaclor Indinavir may decrease the excretion rate of Cefaclor which could result in a higher serum level.
Bacillus Calmette-Guerin (BCG) Vaccine	Bacillus Calmette-Guerin (BCG) Vaccine The therapeutic efficacy of Bacillus calmette-guerin substrain tice live antigen can be decreased when used in combination with Indinavir.
Ketoconazole	Ketoconazole The metabolism of Indinavir can be decreased when combined with Ketoconazole.
Vincristine Injection	Vincristine Injection The metabolism of Vincristine can be decreased when combined with Indinavir.
Captopril	Captopril The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Indinavir is combined with Captopril.
Dipyridamole	Dipyridamole Indinavir may decrease the excretion rate of Dipyridamole which could result in a higher serum level.
Vinblastine	Vinblastine Vinblastine may decrease the excretion rate of Indinavir which could result in a higher serum level.
Hydroxyzine	Hydroxyzine The metabolism of Hydroxyzine can be decreased when combined with Indinavir.
Alprazolam	Alprazolam The metabolism of Alprazolam can be decreased when combined with Indinavir.
Triazolam	Triazolam The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Indinavir is combined with Triazolam.
Trimethoprim	Trimethoprim The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Indinavir is combined with Trimethoprim.
Diltiazem	Diltiazem The metabolism of Indinavir can be decreased when combined with Diltiazem.
Nifedipine	Nifedipine Indinavir may decrease the excretion rate of Nifedipine which could result in a higher serum level.
Verapamil	Verapamil The metabolism of Indinavir can be decreased when combined with Verapamil.
Atenolol	Atenolol Indinavir may decrease the excretion rate of Atenolol which could result in a higher serum level.
Bumetanide	Bumetanide The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Indinavir is combined with Bumetanide.
Etoposide	Etoposide The metabolism of Etoposide can be decreased when combined with Indinavir.
Glyburide	Glyburide Indinavir may decrease the excretion rate of Glyburide which could result in a higher serum level.
Glipizide	Glipizide The metabolism of Glipizide can be decreased when combined with Indinavir.
Pentamidine Injection	Pentamidine Injection The therapeutic efficacy of Pentamidine can be decreased when used in combination with Indinavir.
Labetalol	Labetalol The metabolism of Labetalol can be decreased when combined with Indinavir.
Leuprolide Injection	Leuprolide Injection The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Leuprolide is combined with Indinavir.
Gemfibrozil	Gemfibrozil The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Indinavir is combined with Gemfibrozil.
Ketoprofen	Ketoprofen The metabolism of Ketoprofen can be decreased when combined with Indinavir.
Pimozide	Pimozide The metabolism of Pimozide can be decreased when combined with Indinavir.
Enalapril	Enalapril The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Indinavir is combined with Enalapril.
Flurbiprofen	Flurbiprofen The metabolism of Flurbiprofen can be decreased when combined with Indinavir.
Amiodarone	Amiodarone The serum concentration of Amiodarone can be increased when it is combined with Indinavir.
Buspirone	Buspirone The metabolism of Buspirone can be decreased when combined with Indinavir.
Lovastatin	Lovastatin The metabolism of Lovastatin can be decreased when combined with Indinavir.
Ciprofloxacin	Ciprofloxacin The metabolism of Indinavir can be decreased when combined with Ciprofloxacin.
Diclofenac	Diclofenac Indinavir may decrease the excretion rate of Diclofenac which could result in a higher serum level.
Ofloxacin	Ofloxacin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Indinavir is combined with Ofloxacin.
Didanosine	Didanosine Didanosine can cause a decrease in the absorption of Indinavir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Clarithromycin	Clarithromycin The serum concentration of Clarithromycin can be increased when it is combined with Indinavir.
Felodipine	Felodipine Indinavir may decrease the excretion rate of Felodipine which could result in a higher serum level.
Pravastatin	Pravastatin Indinavir may decrease the excretion rate of Pravastatin which could result in a higher serum level.
Simvastatin	Simvastatin Indinavir may decrease the excretion rate of Simvastatin which could result in a higher serum level.
Teniposide Injection	Teniposide Injection The metabolism of Teniposide can be decreased when combined with Indinavir.
Itraconazole	Itraconazole The metabolism of Indinavir can be decreased when combined with Itraconazole.
Atovaquone	Atovaquone Atovaquone can cause a decrease in the absorption of Indinavir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Rifabutin	Rifabutin The serum concentration of the active metabolites of Rifabutin can be increased when Rifabutin is used in combination with Indinavir.
Isradipine	Isradipine Indinavir may decrease the excretion rate of Isradipine which could result in a higher serum level.
Omeprazole	Omeprazole Omeprazole can cause a decrease in the absorption of Indinavir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Cisapride	Cisapride The serum concentration of Cisapride can be increased when it is combined with Indinavir.
Fluvastatin	Fluvastatin The metabolism of Fluvastatin can be decreased when combined with Indinavir.
Venlafaxine	Venlafaxine The serum concentration of Indinavir can be decreased when it is combined with Venlafaxine.
Nizatidine	Nizatidine Nizatidine can cause a decrease in the absorption of Indinavir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Stavudine	Stavudine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Indinavir is combined with Stavudine.
Fluvoxamine	Fluvoxamine Fluvoxamine may decrease the excretion rate of Indinavir which could result in a higher serum level.
Nefazodone	Nefazodone Indinavir may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Lamotrigine	Lamotrigine The metabolism of Lamotrigine can be decreased when combined with Indinavir.
Losartan	Losartan The metabolism of Losartan can be decreased when combined with Indinavir.
Tramadol	Tramadol The metabolism of Indinavir can be decreased when combined with Tramadol.
Lansoprazole	Lansoprazole Lansoprazole can cause a decrease in the absorption of Indinavir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ifosfamide Injection	Ifosfamide Injection The metabolism of Ifosfamide can be decreased when combined with Indinavir.
Nicardipine	Nicardipine Indinavir may decrease the excretion rate of Nicardipine which could result in a higher serum level.
Saquinavir	Saquinavir The metabolism of Indinavir can be decreased when combined with Saquinavir.
Metformin	Metformin The therapeutic efficacy of Metformin can be decreased when used in combination with Indinavir.
Nisoldipine	Nisoldipine The metabolism of Nisoldipine can be decreased when combined with Indinavir.
Lamivudine	Lamivudine The risk or severity of adverse effects can be increased when Indinavir is combined with Lamivudine.
Acarbose	Acarbose The therapeutic efficacy of Acarbose can be decreased when used in combination with Indinavir.
Glimepiride	Glimepiride The therapeutic efficacy of Glimepiride can be decreased when used in combination with Indinavir.
Ritonavir	Ritonavir The serum concentration of Indinavir can be increased when it is combined with Ritonavir.
Docetaxel Injection	Docetaxel Injection The metabolism of Docetaxel can be decreased when combined with Indinavir.
Valsartan	Valsartan The excretion of Valsartan can be decreased when combined with Indinavir.
Insulin Lispro Injection	Insulin Lispro Injection The therapeutic efficacy of Insulin lispro can be decreased when used in combination with Indinavir.
Pramipexole	Pramipexole The risk or severity of adverse effects can be increased when Indinavir is combined with Pramipexole.
Nelfinavir	Nelfinavir The metabolism of Indinavir can be decreased when combined with Nelfinavir.
Fexofenadine	Fexofenadine The excretion of Fexofenadine can be decreased when combined with Indinavir.
Loratadine	Loratadine Indinavir may decrease the excretion rate of Loratadine which could result in a higher serum level.
Carvedilol	Carvedilol The metabolism of Carvedilol can be decreased when combined with Indinavir.
Flutamide	Flutamide The metabolism of Flutamide can be decreased when combined with Indinavir.
Letrozole	Letrozole The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Indinavir is combined with Letrozole.
Raloxifene	Raloxifene The metabolism of Raloxifene can be decreased when combined with Indinavir.
Finasteride	Finasteride The metabolism of Finasteride can be decreased when combined with Indinavir.
Quetiapine	Quetiapine The metabolism of Quetiapine can be decreased when combined with Indinavir.
Efavirenz	Efavirenz The serum concentration of Indinavir can be decreased when it is combined with Efavirenz.
Abacavir	Abacavir The metabolism of Abacavir can be decreased when combined with Indinavir.
Sildenafil	Sildenafil The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Indinavir is combined with Sildenafil.
Pioglitazone	Pioglitazone The therapeutic efficacy of Pioglitazone can be decreased when used in combination with Indinavir.
Celecoxib	Celecoxib Celecoxib may decrease the excretion rate of Indinavir which could result in a higher serum level.
Rosiglitazone	Rosiglitazone Indinavir may decrease the excretion rate of Rosiglitazone which could result in a higher serum level.
Thalidomide	Thalidomide The metabolism of Indinavir can be increased when combined with Thalidomide.
Aluminum Hydroxide	Aluminum Hydroxide Aluminum hydroxide can cause a decrease in the absorption of Indinavir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Nateglinide	Nateglinide The therapeutic efficacy of Nateglinide can be decreased when used in combination with Indinavir.
Rabeprazole	Rabeprazole Rabeprazole can cause a decrease in the absorption of Indinavir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Terbinafine	Terbinafine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Indinavir is combined with Terbinafine.