Secobarbital
Generic name: Pronounced as (see koe bar' bi tal)
Medical Content Reviewed By HelloPharmacist Staff
Last Revised - 06/15/2017
On this page
- Why is this medication prescribed?
- How should this medicine be used?
- Other uses for this medicine
- What special precautions should I follow?
- What special dietary instructions should I follow?
- What should I do if I forget a dose?
- What side effects can this medication cause?
- What should I know about STORAGE and DISPOSAL of this medication?
- What should I do in case of OVERDOSE?
- What OTHER INFORMATION should I know?
- Other names
- Drug interactions
Why is this medication prescribed?
Secobarbital is used on a short-term basis to treat insomnia (difficulty falling asleep or staying asleep). It is also used to relieve anxiety before surgery. Secobarbital is in a class of medications called barbiturates. It works by slowing activity in the brain.
How should this medicine be used?
Secobarbital comes as a capsule to take by mouth. When secobarbital is used to treat insomnia, it is usually taken at bedtime as needed for sleep. When secobarbital is used to relieve anxiety before surgery, it is usually taken 1 to 2 hours before surgery. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take secobarbital exactly as directed.
Your sleep problems should improve within 7 to 10 days after you start taking secobarbital. Call your doctor if your sleep problems do not improve during this time, if they get worse at any time during your treatment, or if you notice any changes in your thoughts or behavior.
Secobarbital should normally be taken for short periods of time. If you take secobarbital for 2 weeks or longer, secobarbital may not help you sleep as well as it did when you first began to take the medication. If you take secobarbital for a long time, you may also develop dependence ('addiction,' a need to continue taking the medication) on secobarbital. Talk to your doctor about the risks of taking secobarbital for 2 weeks or longer. Do not take a larger dose of secobarbital, take it more often, or take it for a longer time than prescribed by your doctor.
Do not stop taking secobarbital without talking to your doctor. Your doctor will probably decrease your dose gradually. If you suddenly stop taking secobarbital, you may develop anxiety, muscle twitching, uncontrollable shaking of your hands or fingers, weakness, dizziness, changes in vision, nausea, vomiting, or difficulty falling asleep or staying asleep, or you may experience more severe withdrawal symptoms such as seizures or extreme confusion.
Other uses for this medicine
This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
What special precautions should I follow?
Before taking secobarbital,
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tell your doctor and pharmacist if you are allergic to secobarbital; other barbiturates such as amobarbital (Amytal, in Tuinal), butabarbital (Butisol), pentobarbital, or phenobarbital; any other medications, or any of the ingredients in secobarbital capsules. Ask your pharmacist for a list of the ingredients.
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tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: anticoagulants ('blood thinners') such as warfarin (Coumadin); antihistamines; doxycycline (Doryx, Vibramycin; Vibra-tabs); griseofulvin (Fulvicin-U/F, Grifulvin V, Gris-PEG ); hormone replacement therapy; monoamine oxidase (MAO) inhibitors such as isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate); medications for depression,pain, colds, or allergies; certain medictations for seizures such as phenytoin (Dilantin) and valproic acid (Depakene); muscle relaxants; oral steroids such as dexamethasone (Decadron, Dexone), methylprednisolone (Medrol), and prednisone (Deltasone); sedatives; sleeping pills; and tranquilizers. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
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tell your doctor if you have or have ever had porphyria (condition in which certain natural substances build up in the body and may cause stomach pain, changes in thinking and behavior, and other symptoms); any condition that causes shortness of breath or difficulty breathing; or liver disease. Your doctor will probably tell you not to take secobarbital.
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tell your doctor if you drink or have ever drunk large amounts of alcohol, use or have ever used street drugs, or have overused prescription medications.Also tell your doctor if you have ever thought about killing yourself or tried to do so and if you have or have ever had depression; pain; or kidney disease.
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tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking secobarbital, call your doctor.
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you should know that secobarbital may decrease the effectiveness of hormonal contraceptives (birth control pills, patches, rings, injections, implants, or intrauterine devices). Talk to your doctor about methods of birth control that will work for you while you are taking secobarbital. Tell your doctor if you have a missed period or think you may be pregnant while you are taking secobarbital.
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talk to your doctor about the risks and benefits of taking this medication if you are 65 years of age or older. Older adults should not usually take secobarbital to treat conditions other than seizures because it is not as safe as other medications that can be used to treat the same conditions.
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if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking secobarbital.
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you should know that this medication may make you drowsy during the daytime. Do not drive a car or operate machinery until you know how this medication affects you.
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do not drink alcohol during your treatment with secobarbital. Alcohol can make the side effects of secobarbital worse.
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you should know that some people who took medications for sleep got out of bed and drove their cars, prepared and ate food, had sex, made phone calls, or were involved in other activities while partially asleep. After they woke up, these people were usually unable to remember what they had done. Call your doctor right away if you find out that you have been driving or doing anything else while you were sleeping.
What special dietary instructions should I follow?
Unless your doctor tells you otherwise, continue your normal diet.
What should I do if I forget a dose?
Secobarbital is usually taken at bedtime. If you forget to take secobarbital at bedtime, you are unable to fall asleep, and you will still be able to stay in bed for a full night's sleep, you may take secobarbital at that time. Do not take a double dose of secobarbital to make up for a missed dose.
What side effects can this medication cause?
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Secobarbital may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
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drowsiness
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difficulty falling asleep or staying asleep
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nightmares
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headache
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dizziness
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nervousness
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agitation
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excitement
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restlessness
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confusion
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nausea
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vomiting
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diarrhea
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constipation
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Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:
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hallucinating (seeing things or hearing voices that do not exist)
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slow, shallow breathing
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slow heartbeat
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hives
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rash
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itching
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swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
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difficulty breathing or swallowing
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hoarseness
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Secobarbital may cause other side effects. Tell your doctor if you have any unusual problems during your treatment with secobarbital.
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If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).
What should I know about STORAGE and DISPOSAL of this medication?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).
Store secobarbital in a safe place so that no one else can take it accidentally or on purpose. Keep track of how many capsules are left so you will know if any are missing.
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.
It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org
What should I do in case of OVERDOSE?
In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.
Symptoms of overdose may include:
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slowed breathing
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low body temperature
What OTHER INFORMATION should I know?
Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your response to secobarbital.
This prescription is not refillable.
Do not let anyone else take your medication.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Drug interactions
Drug | Interaction |
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Repaglinide | Repaglinide The metabolism of Repaglinide can be increased when combined with Secobarbital. |
Montelukast | Montelukast The metabolism of Montelukast can be increased when combined with Secobarbital. |
Leflunomide | Leflunomide The metabolism of Leflunomide can be increased when combined with Secobarbital. |
Atorvastatin | Atorvastatin The metabolism of Atorvastatin can be increased when combined with Secobarbital. |
Dolasetron | Dolasetron The risk or severity of adverse effects can be increased when Secobarbital is combined with Dolasetron. |
Aminophylline | Aminophylline The therapeutic efficacy of Secobarbital can be decreased when used in combination with Aminophylline. |
Anagrelide | Anagrelide The metabolism of Anagrelide can be increased when combined with Secobarbital. |
Bisacodyl | Bisacodyl The therapeutic efficacy of Bisacodyl can be decreased when used in combination with Secobarbital. |
Cilostazol | Cilostazol The metabolism of Cilostazol can be increased when combined with Secobarbital. |
Clopidogrel | Clopidogrel The metabolism of Clopidogrel can be increased when combined with Secobarbital. |
Diphenoxylate | Diphenoxylate The risk or severity of adverse effects can be increased when Secobarbital is combined with Diphenoxylate. |
Estrogen and Progestin (Oral Contraceptives) | Estrogen and Progestin (Oral Contraceptives) The metabolism of Secobarbital can be increased when combined with Conjugated estrogens. |
Fenofibrate | Fenofibrate The metabolism of Fenofibrate can be increased when combined with Secobarbital. |
Guanfacine | Guanfacine The risk or severity of adverse effects can be increased when Secobarbital is combined with Guanfacine. |
Magnesium Hydroxide | Magnesium Hydroxide Secobarbital may decrease the excretion rate of Magnesium hydroxide which could result in a higher serum level. |
Magnesium Oxide | Magnesium Oxide The therapeutic efficacy of Magnesium oxide can be decreased when used in combination with Secobarbital. |
Mycophenolate | Mycophenolate Secobarbital may decrease the excretion rate of Mycophenolic acid which could result in a higher serum level. |
Naratriptan | Naratriptan The risk or severity of adverse effects can be increased when Secobarbital is combined with Naratriptan. |
Olsalazine | Olsalazine Olsalazine may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Paregoric | Paregoric The risk or severity of adverse effects can be increased when Secobarbital is combined with Morphine. |
Penbutolol | Penbutolol The serum concentration of Acebutolol can be decreased when it is combined with Secobarbital. |
Pentazocine | Pentazocine The risk or severity of adverse effects can be increased when Secobarbital is combined with Pentazocine. |
Polyethylene glycol-electrolyte solution (PEG-ES) | Polyethylene glycol-electrolyte solution (PEG-ES) The therapeutic efficacy of Polyethylene glycol can be decreased when used in combination with Secobarbital. |
Potassium | Potassium Potassium may increase the excretion rate of Secobarbital which could result in a lower serum level and potentially a reduction in efficacy. |
Prednisone | Prednisone Secobarbital may decrease the excretion rate of Prednisone which could result in a higher serum level. |
Psyllium | Psyllium The therapeutic efficacy of Plantago seed can be decreased when used in combination with Secobarbital. |
Ranitidine | Ranitidine The metabolism of Ranitidine can be increased when combined with Secobarbital. |
Reserpine | Reserpine Secobarbital may increase the hypotensive activities of Reserpine. |
Rizatriptan | Rizatriptan The risk or severity of adverse effects can be increased when Secobarbital is combined with Rizatriptan. |
Sumatriptan | Sumatriptan The risk or severity of adverse effects can be increased when Secobarbital is combined with Sumatriptan. |
Tacrolimus | Tacrolimus The metabolism of Tacrolimus can be increased when combined with Secobarbital. |
Tizanidine | Tizanidine The metabolism of Tizanidine can be increased when combined with Secobarbital. |
Zolmitriptan | Zolmitriptan The metabolism of Zolmitriptan can be increased when combined with Secobarbital. |
Ampicillin Injection | Ampicillin Injection Ampicillin may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Doxycycline Injection | Doxycycline Injection The serum concentration of Doxycycline can be decreased when it is combined with Secobarbital. |
Fluconazole Injection | Fluconazole Injection Fluconazole may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Foscarnet Injection | Foscarnet Injection Foscarnet may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Hydromorphone Injection | Hydromorphone Injection The risk or severity of adverse effects can be increased when Hydromorphone is combined with Secobarbital. |
Levofloxacin Injection | Levofloxacin Injection Secobarbital may decrease the excretion rate of Levofloxacin which could result in a higher serum level. |
Meperidine Injection | Meperidine Injection Secobarbital may increase the hypotensive and central nervous system depressant (CNS depressant) activities of Meperidine. |
Metoclopramide Injection | Metoclopramide Injection The risk or severity of sedation can be increased when Metoclopramide is combined with Secobarbital. |
Metronidazole Injection | Metronidazole Injection The therapeutic efficacy of Secobarbital can be decreased when used in combination with Metronidazole. |
Morphine Injection | Morphine Injection The risk or severity of adverse effects can be increased when Secobarbital is combined with Morphine. |
Pamidronate Injection | Pamidronate Injection Pamidronic acid may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Vancomycin Injection | Vancomycin Injection Secobarbital may decrease the excretion rate of Vancomycin which could result in a higher serum level. |
Zidovudine Injection | Zidovudine Injection The metabolism of Zidovudine can be increased when combined with Secobarbital. |
Altretamine | Altretamine The therapeutic efficacy of Secobarbital can be decreased when used in combination with Amphetamine. |
Cefuroxime | Cefuroxime Cefuroxime may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Cyclosporine | Cyclosporine The metabolism of Cyclosporine can be increased when combined with Secobarbital. |
Ondansetron | Ondansetron The risk or severity of adverse effects can be increased when Secobarbital is combined with Ondansetron. |
Granisetron | Granisetron The risk or severity of adverse effects can be increased when Secobarbital is combined with Granisetron. |
Torsemide | Torsemide The metabolism of Torasemide can be increased when combined with Secobarbital. |
Olanzapine | Olanzapine The risk or severity of adverse effects can be increased when Olanzapine is combined with Secobarbital. |
Alosetron | Alosetron The metabolism of Alosetron can be increased when combined with Secobarbital. |
Dofetilide | Dofetilide The metabolism of Dofetilide can be increased when combined with Secobarbital. |
Entacapone | Entacapone The risk or severity of adverse effects can be increased when Secobarbital is combined with Entacapone. |
Eprosartan | Eprosartan Secobarbital may increase the hypotensive activities of Eprosartan. |
Hydroxychloroquine | Hydroxychloroquine The therapeutic efficacy of Hydroxychloroquine can be decreased when used in combination with Secobarbital. |
Meloxicam | Meloxicam Meloxicam may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Orlistat | Orlistat Orlistat can cause a decrease in the absorption of Secobarbital resulting in a reduced serum concentration and potentially a decrease in efficacy. |
Oxcarbazepine | Oxcarbazepine The risk or severity of adverse effects can be increased when Secobarbital is combined with Oxcarbazepine. |
Pantoprazole | Pantoprazole Pantoprazole may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Telmisartan | Telmisartan Secobarbital may increase the hypotensive activities of Telmisartan. |
Temozolomide | Temozolomide Secobarbital may decrease the excretion rate of Temozolomide which could result in a higher serum level. |
Zaleplon | Zaleplon The risk or severity of adverse effects can be increased when Secobarbital is combined with Zaleplon. |
Desloratadine | Desloratadine The risk or severity of adverse effects can be increased when Secobarbital is combined with Desloratadine. |
Linezolid | Linezolid The risk or severity of adverse effects can be increased when Secobarbital is combined with Linezolid. |
Rivastigmine | Rivastigmine The therapeutic efficacy of Secobarbital can be decreased when used in combination with Rivastigmine. |
Trimipramine | Trimipramine The metabolism of Trimipramine can be increased when combined with Secobarbital. |
Glycopyrrolate | Glycopyrrolate Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Glycopyrronium. |
Perindopril | Perindopril Perindopril may increase the hypotensive activities of Secobarbital. |
Tenofovir | Tenofovir Tenofovir may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Choline Magnesium Trisalicylate | Choline Magnesium Trisalicylate Choline magnesium trisalicylate may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Sirolimus | Sirolimus The metabolism of Sirolimus can be increased when combined with Secobarbital. |
Eplerenone | Eplerenone Secobarbital may increase the hypotensive activities of Eplerenone. |
Escitalopram | Escitalopram The risk or severity of adverse effects can be increased when Secobarbital is combined with Escitalopram. |
Olmesartan | Olmesartan Secobarbital may increase the hypotensive activities of Olmesartan. |
Zonisamide | Zonisamide The risk or severity of adverse effects can be increased when Secobarbital is combined with Zonisamide. |
Aripiprazole | Aripiprazole The metabolism of Aripiprazole can be increased when combined with Secobarbital. |
Atomoxetine | Atomoxetine The risk or severity of adverse effects can be increased when Atomoxetine is combined with Secobarbital. |
Dexmethylphenidate | Dexmethylphenidate The risk or severity of adverse effects can be increased when Secobarbital is combined with Dexmethylphenidate. |
Atazanavir | Atazanavir Atazanavir may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Almotriptan | Almotriptan The metabolism of Almotriptan can be increased when combined with Secobarbital. |
Eletriptan | Eletriptan The risk or severity of adverse effects can be increased when Eletriptan is combined with Secobarbital. |
Mefloquine | Mefloquine The therapeutic efficacy of Secobarbital can be decreased when used in combination with Mefloquine. |
Polyethylene Glycol 3350 | Polyethylene Glycol 3350 The therapeutic efficacy of Polyethylene glycol can be decreased when used in combination with Secobarbital. |
Rosuvastatin | Rosuvastatin The metabolism of Rosuvastatin can be increased when combined with Secobarbital. |
Emtricitabine | Emtricitabine Secobarbital may decrease the excretion rate of Emtricitabine which could result in a higher serum level. |
Memantine | Memantine The therapeutic efficacy of Secobarbital can be decreased when used in combination with Memantine. |
Tegaserod | Tegaserod The therapeutic efficacy of Tegaserod can be decreased when used in combination with Secobarbital. |
Tadalafil | Tadalafil Secobarbital may decrease the excretion rate of Tadalafil which could result in a higher serum level. |
Frovatriptan | Frovatriptan The metabolism of Frovatriptan can be increased when combined with Secobarbital. |
Progesterone | Progesterone The metabolism of Progesterone can be increased when combined with Secobarbital. |
Apomorphine Injection | Apomorphine Injection The metabolism of Apomorphine can be increased when combined with Secobarbital. |
Protriptyline | Protriptyline The metabolism of Protriptyline can be increased when combined with Secobarbital. |
Duloxetine | Duloxetine The risk or severity of adverse effects can be increased when Secobarbital is combined with Duloxetine. |
Norethindrone | Norethindrone The metabolism of Norethisterone can be increased when combined with Secobarbital. |
Tinidazole | Tinidazole Secobarbital may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
Trospium | Trospium Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Trospium. |
Cefditoren | Cefditoren Secobarbital may decrease the excretion rate of Cefdinir which could result in a higher serum level. |
Cinacalcet | Cinacalcet The metabolism of Cinacalcet can be increased when combined with Secobarbital. |
Cyanocobalamin Injection | Cyanocobalamin Injection Hydroxocobalamin may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Erlotinib | Erlotinib The serum concentration of Erlotinib can be decreased when it is combined with Secobarbital. |
Eszopiclone | Eszopiclone The risk or severity of CNS depression can be increased when Secobarbital is combined with Eszopiclone. |
Ganciclovir | Ganciclovir The therapeutic efficacy of Ganciclovir can be decreased when used in combination with Secobarbital. |
Ribavirin | Ribavirin Secobarbital may decrease the excretion rate of Ribavirin which could result in a higher serum level. |
Solifenacin | Solifenacin Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Solifenacin. |
Valganciclovir | Valganciclovir The therapeutic efficacy of Valganciclovir can be decreased when used in combination with Secobarbital. |
Voriconazole | Voriconazole The serum concentration of Voriconazole can be decreased when it is combined with Secobarbital. |
Adefovir | Adefovir Adefovir may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Dextroamphetamine | Dextroamphetamine The therapeutic efficacy of Secobarbital can be decreased when used in combination with Amphetamine. |
Entecavir | Entecavir The metabolism of Entecavir can be increased when combined with Secobarbital. |
Sodium Oxybate | Sodium Oxybate Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate. |
Isocarboxazid | Isocarboxazid Secobarbital may increase the hypotensive activities of Isocarboxazid. |
Ramelteon | Ramelteon The risk or severity of adverse effects can be increased when Secobarbital is combined with Ramelteon. |
Darifenacin | Darifenacin Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Darifenacin. |
Fentanyl | Fentanyl The risk or severity of adverse effects can be increased when Secobarbital is combined with Fentanyl. |
Pregabalin | Pregabalin The therapeutic efficacy of Secobarbital can be increased when used in combination with Pregabalin. |
Felbamate | Felbamate The serum concentration of Secobarbital can be increased when it is combined with Felbamate. |
Ranolazine | Ranolazine The metabolism of Secobarbital can be increased when combined with Ranolazine. |
Rasagiline | Rasagiline Secobarbital may increase the hypotensive activities of Rasagiline. |
Imatinib | Imatinib The metabolism of Imatinib can be increased when combined with Secobarbital. |
Sitagliptin | Sitagliptin The metabolism of Sitagliptin can be increased when combined with Secobarbital. |
Varenicline | Varenicline Secobarbital may decrease the excretion rate of Varenicline which could result in a higher serum level. |
Albuterol | Albuterol Secobarbital may decrease the excretion rate of Salbutamol which could result in a higher serum level. |
Paliperidone | Paliperidone The risk or severity of adverse effects can be increased when Secobarbital is combined with Paliperidone. |
Bortezomib | Bortezomib The metabolism of Bortezomib can be increased when combined with Secobarbital. |
Clofarabine Injection | Clofarabine Injection Secobarbital may increase the hypotensive activities of Clofarabine. |
Lubiprostone | Lubiprostone Secobarbital may decrease the excretion rate of Lubiprostone which could result in a higher serum level. |
Primaquine | Primaquine The metabolism of Primaquine can be increased when combined with Secobarbital. |
Aliskiren | Aliskiren Secobarbital may increase the hypotensive activities of Aliskiren. |
Pemetrexed Injection | Pemetrexed Injection Secobarbital may decrease the excretion rate of Pemetrexed which could result in a higher serum level. |
Dimenhydrinate | Dimenhydrinate The risk or severity of adverse effects can be increased when Secobarbital is combined with Dimenhydrinate. |
Nabilone | Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Secobarbital. |
Retapamulin | Retapamulin The metabolism of Retapamulin can be increased when combined with Secobarbital. |
Sorafenib | Sorafenib The metabolism of Sorafenib can be increased when combined with Secobarbital. |
Sunitinib | Sunitinib The metabolism of Sunitinib can be increased when combined with Secobarbital. |
Dronabinol | Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Secobarbital. |
Lapatinib | Lapatinib The metabolism of Lapatinib can be increased when combined with Secobarbital. |
Levocetirizine | Levocetirizine The risk or severity of adverse effects can be increased when Secobarbital is combined with Levocetirizine. |
Pegaptanib Injection | Pegaptanib Injection Secobarbital may decrease the excretion rate of Pegaptanib which could result in a higher serum level. |
Dasatinib | Dasatinib The metabolism of Dasatinib can be increased when combined with Secobarbital. |
Mexiletine | Mexiletine The metabolism of Mexiletine can be increased when combined with Secobarbital. |
Azacitidine Injection | Azacitidine Injection Secobarbital may decrease the excretion rate of Azacitidine which could result in a higher serum level. |
Paclitaxel (with polyoxyethylated castor oil) Injection | Paclitaxel (with polyoxyethylated castor oil) Injection The therapeutic efficacy of Castor oil can be decreased when used in combination with Secobarbital. |
Temsirolimus | Temsirolimus The metabolism of Temsirolimus can be increased when combined with Secobarbital. |
Lenalidomide | Lenalidomide Secobarbital may decrease the excretion rate of Lenalidomide which could result in a higher serum level. |
Nilotinib | Nilotinib The metabolism of Nilotinib can be increased when combined with Secobarbital. |
Budesonide | Budesonide Secobarbital may decrease the excretion rate of Budesonide which could result in a higher serum level. |
Chloramphenicol Injection | Chloramphenicol Injection The metabolism of Secobarbital can be decreased when combined with Chloramphenicol. |
Desmopressin | Desmopressin Desmopressin may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Betaine | Betaine The therapeutic efficacy of Secobarbital can be decreased when used in combination with Glycine betaine. |
OnabotulinumtoxinA Injection | OnabotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Secobarbital is combined with Botulinum toxin type A. |
RimabotulinumtoxinB Injection | RimabotulinumtoxinB Injection The risk or severity of adverse effects can be increased when Secobarbital is combined with Botulinum Toxin Type B. |
Doripenem Injection | Doripenem Injection Secobarbital may decrease the excretion rate of Doripenem which could result in a higher serum level. |
Arsenic Trioxide Injection | Arsenic Trioxide Injection Secobarbital may increase the hypotensive activities of Arsenic trioxide. |
Desvenlafaxine | Desvenlafaxine The risk or severity of adverse effects can be increased when Secobarbital is combined with Desvenlafaxine. |
Cevimeline | Cevimeline Cevimeline may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Nebivolol | Nebivolol The serum concentration of Nebivolol can be decreased when it is combined with Secobarbital. |
Tretinoin | Tretinoin The metabolism of Tretinoin can be increased when combined with Secobarbital. |
Bendamustine Injection | Bendamustine Injection The metabolism of Bendamustine can be increased when combined with Secobarbital. |
Flecainide | Flecainide The metabolism of Flecainide can be increased when combined with Secobarbital. |
Certolizumab Injection | Certolizumab Injection Secobarbital may decrease the excretion rate of Certolizumab pegol which could result in a higher serum level. |
Ixabepilone Injection | Ixabepilone Injection The metabolism of Ixabepilone can be increased when combined with Secobarbital. |
Irinotecan Injection | Irinotecan Injection The metabolism of Irinotecan can be increased when combined with Secobarbital. |
Daptomycin Injection | Daptomycin Injection Daptomycin may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Praziquantel | Praziquantel The metabolism of Praziquantel can be increased when combined with Secobarbital. |
Methylnaltrexone Injection | Methylnaltrexone Injection Secobarbital may decrease the excretion rate of Methylnaltrexone which could result in a higher serum level. |
Rufinamide | Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Secobarbital. |
Midazolam | Midazolam The risk or severity of adverse effects can be increased when Secobarbital is combined with Midazolam. |
Naltrexone Injection | Naltrexone Injection The risk or severity of adverse effects can be increased when Secobarbital is combined with Naltrexone. |
Dexrazoxane Injection | Dexrazoxane Injection Dexrazoxane may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Eltrombopag | Eltrombopag The metabolism of Eltrombopag can be increased when combined with Secobarbital. |
Milnacipran | Milnacipran The metabolism of Milnacipran can be increased when combined with Secobarbital. |
Plerixafor Injection | Plerixafor Injection Secobarbital may decrease the excretion rate of Plerixafor which could result in a higher serum level. |
Sodium Phosphate | Sodium Phosphate The therapeutic efficacy of Secobarbital can be decreased when used in combination with Sodium phosphate, monobasic. |
Fesoterodine | Fesoterodine Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Fesoterodine. |
Betaxolol | Betaxolol The serum concentration of Betaxolol can be decreased when it is combined with Secobarbital. |
Iloperidone | Iloperidone The risk or severity of adverse effects can be increased when Secobarbital is combined with Iloperidone. |
Prasugrel | Prasugrel Secobarbital may decrease the excretion rate of Prasugrel which could result in a higher serum level. |
Lacosamide | Lacosamide The risk or severity of adverse effects can be increased when Secobarbital is combined with Lacosamide. |
Everolimus | Everolimus The metabolism of Everolimus can be increased when combined with Secobarbital. |
Tolvaptan (low blood sodium) | Tolvaptan (low blood sodium) The metabolism of Secobarbital can be increased when combined with Tolvaptan. |
Dronedarone | Dronedarone The metabolism of Dronedarone can be increased when combined with Secobarbital. |
AbobotulinumtoxinA Injection | AbobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Secobarbital is combined with Botulinum toxin type A. |
Pralatrexate Injection | Pralatrexate Injection Secobarbital may decrease the excretion rate of Pralatrexate which could result in a higher serum level. |
Palonosetron Injection | Palonosetron Injection The risk or severity of adverse effects can be increased when Palonosetron is combined with Secobarbital. |
Saxagliptin | Saxagliptin Secobarbital may decrease the excretion rate of Saxagliptin which could result in a higher serum level. |
Telavancin Injection | Telavancin Injection Secobarbital may decrease the excretion rate of Telavancin which could result in a higher serum level. |
Romidepsin Injection | Romidepsin Injection The metabolism of Romidepsin can be increased when combined with Secobarbital. |
Tapentadol | Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Secobarbital. |
Topotecan | Topotecan Secobarbital may increase the excretion rate of Topotecan which could result in a lower serum level and potentially a reduction in efficacy. |
Pazopanib | Pazopanib The metabolism of Pazopanib can be increased when combined with Secobarbital. |
Asenapine | Asenapine The risk or severity of adverse effects can be increased when Secobarbital is combined with Asenapine. |
Vigabatrin | Vigabatrin The risk or severity of adverse effects can be increased when Secobarbital is combined with Vigabatrin. |
Pitavastatin | Pitavastatin The metabolism of Pitavastatin can be increased when combined with Secobarbital. |
Albendazole | Albendazole The metabolism of Albendazole can be increased when combined with Secobarbital. |
Ulipristal | Ulipristal The serum concentration of Ulipristal can be decreased when it is combined with Secobarbital. |
Levonorgestrel | Levonorgestrel The metabolism of Levonorgestrel can be increased when combined with Secobarbital. |
Oxymorphone | Oxymorphone The risk or severity of adverse effects can be increased when Secobarbital is combined with Oxymorphone. |
Dalfampridine | Dalfampridine Secobarbital may decrease the excretion rate of Dalfampridine which could result in a higher serum level. |
IncobotulinumtoxinA Injection | IncobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Secobarbital is combined with Botulinum toxin type A. |
Cabazitaxel Injection | Cabazitaxel Injection The metabolism of Cabazitaxel can be increased when combined with Secobarbital. |
Ceftaroline Injection | Ceftaroline Injection Ceftaroline fosamil may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Lurasidone | Lurasidone The risk or severity of adverse effects can be increased when Secobarbital is combined with Lurasidone. |
Acetaminophen Injection | Acetaminophen Injection The metabolism of Secobarbital can be increased when combined with Acetaminophen. |
Vilazodone | Vilazodone The risk or severity of adverse effects can be increased when Secobarbital is combined with Vilazodone. |
Ipilimumab Injection | Ipilimumab Injection Secobarbital may decrease the excretion rate of Ipilimumab which could result in a higher serum level. |
Denileukin Diftitox Injection | Denileukin Diftitox Injection Secobarbital may increase the hypotensive activities of Aldesleukin. |
Terbutaline Injection | Terbutaline Injection The therapeutic efficacy of Secobarbital can be decreased when used in combination with Terbutaline. |
Azilsartan | Azilsartan Secobarbital may increase the hypotensive activities of Azilsartan medoxomil. |
Busulfan Injection | Busulfan Injection The metabolism of Busulfan can be increased when combined with Secobarbital. |
Roflumilast | Roflumilast The metabolism of Roflumilast can be increased when combined with Secobarbital. |
Linagliptin | Linagliptin The metabolism of Linagliptin can be increased when combined with Secobarbital. |
Cyclophosphamide Injection | Cyclophosphamide Injection The metabolism of Cyclophosphamide can be increased when combined with Secobarbital. |
Rivaroxaban | Rivaroxaban Secobarbital may decrease the excretion rate of Rivaroxaban which could result in a higher serum level. |
Brentuximab Vedotin Injection | Brentuximab Vedotin Injection The metabolism of Brentuximab vedotin can be increased when combined with Secobarbital. |
Ruxolitinib | Ruxolitinib The metabolism of Ruxolitinib can be increased when combined with Secobarbital. |
Vandetanib | Vandetanib The metabolism of Vandetanib can be increased when combined with Secobarbital. |
Clobazam | Clobazam The risk or severity of adverse effects can be increased when Clobazam is combined with Secobarbital. |
Vemurafenib | Vemurafenib The metabolism of Vemurafenib can be increased when combined with Secobarbital. |
Deferiprone | Deferiprone Secobarbital may decrease the excretion rate of Deferiprone which could result in a higher serum level. |
Axitinib | Axitinib The metabolism of Axitinib can be increased when combined with Secobarbital. |
Crizotinib | Crizotinib The metabolism of Crizotinib can be increased when combined with Secobarbital. |
Cabergoline | Cabergoline The metabolism of Secobarbital can be increased when combined with Cabergoline. |
Naloxone Injection | Naloxone Injection Secobarbital may decrease the excretion rate of Naloxone which could result in a higher serum level. |
Fondaparinux Injection | Fondaparinux Injection Secobarbital may decrease the excretion rate of Fondaparinux which could result in a higher serum level. |
Ezogabine | Ezogabine The risk or severity of adverse effects can be increased when Secobarbital is combined with Tiagabine. |
Iloprost | Iloprost Secobarbital may increase the hypotensive activities of Iloprost. |
Enzalutamide | Enzalutamide The metabolism of Enzalutamide can be increased when combined with Secobarbital. |
Mirabegron | Mirabegron Secobarbital may decrease the excretion rate of Mirabegron which could result in a higher serum level. |
Regorafenib | Regorafenib The metabolism of Regorafenib can be increased when combined with Secobarbital. |
Bosutinib | Bosutinib The metabolism of Bosutinib can be increased when combined with Secobarbital. |
Linaclotide | Linaclotide The therapeutic efficacy of Linaclotide can be decreased when used in combination with Secobarbital. |
Cabozantinib (thyroid cancer) | Cabozantinib (thyroid cancer) The metabolism of Cabozantinib can be increased when combined with Secobarbital. |
Teduglutide Injection | Teduglutide Injection Secobarbital may decrease the excretion rate of Teduglutide which could result in a higher serum level. |
Alogliptin | Alogliptin Secobarbital may decrease the excretion rate of Alogliptin which could result in a higher serum level. |
Ponatinib | Ponatinib The metabolism of Ponatinib can be increased when combined with Secobarbital. |
Pomalidomide | Pomalidomide The metabolism of Pomalidomide can be increased when combined with Secobarbital. |
Ado-trastuzumab Emtansine Injection | Ado-trastuzumab Emtansine Injection The metabolism of Trastuzumab emtansine can be increased when combined with Secobarbital. |
Apixaban | Apixaban The metabolism of Apixaban can be increased when combined with Secobarbital. |
Canagliflozin | Canagliflozin The serum concentration of Canagliflozin can be decreased when it is combined with Secobarbital. |
Methazolamide | Methazolamide Secobarbital may increase the hypotensive activities of Methazolamide. |
Dabrafenib | Dabrafenib The metabolism of Dabrafenib can be increased when combined with Secobarbital. |
Trametinib | Trametinib Secobarbital may decrease the excretion rate of Trametinib which could result in a higher serum level. |
Levomilnacipran | Levomilnacipran The metabolism of Levomilnacipran can be increased when combined with Secobarbital. |
Ertapenem Injection | Ertapenem Injection Ertapenem may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Vortioxetine | Vortioxetine The metabolism of Vortioxetine can be increased when combined with Secobarbital. |
Perampanel | Perampanel The metabolism of Perampanel can be increased when combined with Secobarbital. |
Lomitapide | Lomitapide The metabolism of Lomitapide can be increased when combined with Secobarbital. |
Ketorolac Injection | Ketorolac Injection The metabolism of Secobarbital can be increased when combined with Ketorolac. |
Obinutuzumab Injection | Obinutuzumab Injection Secobarbital may increase the hypotensive activities of Obinutuzumab. |
Sofosbuvir | Sofosbuvir Secobarbital may decrease the excretion rate of Sofosbuvir which could result in a higher serum level. |
Dapagliflozin | Dapagliflozin Secobarbital may increase the hypotensive activities of Dapagliflozin. |
Apremilast | Apremilast The metabolism of Apremilast can be increased when combined with Secobarbital. |
Droxidopa | Droxidopa Secobarbital may decrease the excretion rate of Droxidopa which could result in a higher serum level. |
Ceritinib | Ceritinib The metabolism of Ceritinib can be increased when combined with Secobarbital. |
Eslicarbazepine | Eslicarbazepine The risk or severity of adverse effects can be increased when Secobarbital is combined with Eslicarbazepine. |
Idelalisib | Idelalisib The metabolism of Idelalisib can be increased when combined with Secobarbital. |
Testosterone Injection | Testosterone Injection Secobarbital may decrease the excretion rate of Testosterone which could result in a higher serum level. |
Empagliflozin | Empagliflozin Secobarbital may increase the hypotensive activities of Empagliflozin. |
Vorapaxar | Vorapaxar The metabolism of Vorapaxar can be increased when combined with Secobarbital. |
Hydrocodone | Hydrocodone Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone. |
Suvorexant | Suvorexant Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Suvorexant. |
Edoxaban | Edoxaban Secobarbital may decrease the excretion rate of Edoxaban which could result in a higher serum level. |
Olaparib | Olaparib The metabolism of Olaparib can be increased when combined with Secobarbital. |
Methamphetamine | Methamphetamine The risk or severity of adverse effects can be increased when Secobarbital is combined with Metamfetamine. |
Tasimelteon | Tasimelteon The risk or severity of adverse effects can be increased when Secobarbital is combined with Tasimelteon. |
Riociguat | Riociguat The metabolism of Riociguat can be increased when combined with Secobarbital. |
Pirfenidone | Pirfenidone The metabolism of Pirfenidone can be increased when combined with Secobarbital. |
Nintedanib | Nintedanib The metabolism of Nintedanib can be increased when combined with Secobarbital. |
Risperidone Injection | Risperidone Injection The risk or severity of adverse effects can be increased when Secobarbital is combined with Risperidone. |
Palbociclib | Palbociclib The metabolism of Palbociclib can be increased when combined with Secobarbital. |
Panobinostat | Panobinostat The metabolism of Panobinostat can be increased when combined with Secobarbital. |
Dinutuximab Injection | Dinutuximab Injection Secobarbital may increase the hypotensive activities of Dinutuximab. |
Haloperidol Injection | Haloperidol Injection The risk or severity of CNS depression can be increased when Secobarbital is combined with Haloperidol. |
Amiloride | Amiloride Secobarbital may increase the hypotensive activities of Amiloride. |
Macitentan | Macitentan Secobarbital may decrease the excretion rate of Macitentan which could result in a higher serum level. |
Sonidegib | Sonidegib The metabolism of Sonidegib can be increased when combined with Secobarbital. |
Flibanserin | Flibanserin The risk or severity of adverse effects can be increased when Secobarbital is combined with Flibanserin. |
Brexpiprazole | Brexpiprazole The risk or severity of adverse effects can be increased when Secobarbital is combined with Brexpiprazole. |
Ziprasidone Injection | Ziprasidone Injection The risk or severity of adverse effects can be increased when Ziprasidone is combined with Secobarbital. |
Cariprazine | Cariprazine The risk or severity of adverse effects can be increased when Secobarbital is combined with Cariprazine. |
Penicillin G Procaine Injection | Penicillin G Procaine Injection Secobarbital may decrease the excretion rate of Procaine benzylpenicillin which could result in a higher serum level. |
Eluxadoline | Eluxadoline The risk or severity of constipation can be increased when Secobarbital is combined with Eluxadoline. |
Cobimetinib | Cobimetinib The metabolism of Cobimetinib can be increased when combined with Secobarbital. |
Trabectedin Injection | Trabectedin Injection The metabolism of Trabectedin can be increased when combined with Secobarbital. |
Osimertinib | Osimertinib The metabolism of Osimertinib can be increased when combined with Secobarbital. |
Alectinib | Alectinib The metabolism of Alectinib can be increased when combined with Secobarbital. |
Ixazomib | Ixazomib The metabolism of Ixazomib can be increased when combined with Secobarbital. |
Lesinurad | Lesinurad Secobarbital may decrease the excretion rate of Lesinurad which could result in a higher serum level. |
Amphotericin B Liposomal Injection | Amphotericin B Liposomal Injection Secobarbital may increase the hypotensive activities of Amphotericin B. |
Brivaracetam Injection | Brivaracetam Injection The risk or severity of adverse effects can be increased when Secobarbital is combined with Brivaracetam. |
Venetoclax | Venetoclax The metabolism of Venetoclax can be increased when combined with Secobarbital. |
Selexipag | Selexipag The metabolism of Selexipag can be increased when combined with Secobarbital. |
Pimavanserin | Pimavanserin The risk or severity of adverse effects can be increased when Secobarbital is combined with Pimavanserin. |
Diphenhydramine Injection | Diphenhydramine Injection The risk or severity of adverse effects can be increased when Secobarbital is combined with Diphenhydramine. |
Furosemide Injection | Furosemide Injection Secobarbital may increase the hypotensive activities of Furosemide. |
Rucaparib | Rucaparib The metabolism of Rucaparib can be increased when combined with Secobarbital. |
Lixisenatide Injection | Lixisenatide Injection Secobarbital may decrease the excretion rate of Lixisenatide which could result in a higher serum level. |
Ribociclib | Ribociclib The metabolism of Ribociclib can be increased when combined with Secobarbital. |
Brigatinib | Brigatinib The metabolism of Brigatinib can be increased when combined with Secobarbital. |
Doxepin (Insomnia) | Doxepin (Insomnia) Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Doxepin. |
Plecanatide | Plecanatide The therapeutic efficacy of Plecanatide can be decreased when used in combination with Secobarbital. |
Deutetrabenazine | Deutetrabenazine The risk or severity of sedation and somnolence can be increased when Secobarbital is combined with Deutetrabenazine. |
Valbenazine | Valbenazine Secobarbital may decrease the excretion rate of Valbenazine which could result in a higher serum level. |
Safinamide | Safinamide The risk or severity of adverse effects can be increased when Secobarbital is combined with Safinamide. |
Naldemedine | Naldemedine Secobarbital may decrease the excretion rate of Naldemedine which could result in a higher serum level. |
Midostaurin | Midostaurin The metabolism of Midostaurin can be increased when combined with Secobarbital. |
Neratinib | Neratinib The metabolism of Neratinib can be increased when combined with Secobarbital. |
Enasidenib | Enasidenib The metabolism of Enasidenib can be increased when combined with Secobarbital. |
Aprepitant/Fosaprepitant Injection | Aprepitant/Fosaprepitant Injection The metabolism of Fosaprepitant can be increased when combined with Secobarbital. |
Benznidazole | Benznidazole Secobarbital may decrease the excretion rate of Benznidazole which could result in a higher serum level. |
Copanlisib Injection | Copanlisib Injection The metabolism of Copanlisib can be increased when combined with Secobarbital. |
Delafloxacin | Delafloxacin Secobarbital may decrease the excretion rate of Delafloxacin which could result in a higher serum level. |
Abemaciclib | Abemaciclib The metabolism of Abemaciclib can be increased when combined with Secobarbital. |
Acalabrutinib | Acalabrutinib The metabolism of Acalabrutinib can be increased when combined with Secobarbital. |
Tetrabenazine | Tetrabenazine The risk or severity of sedation and somnolence can be increased when Secobarbital is combined with Tetrabenazine. |
Ertugliflozin | Ertugliflozin Ertugliflozin may increase the excretion rate of Secobarbital which could result in a lower serum level and potentially a reduction in efficacy. |
Buprenorphine Injection | Buprenorphine Injection Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine. |
Apalutamide | Apalutamide The metabolism of Apalutamide can be increased when combined with Secobarbital. |
Baricitinib | Baricitinib The metabolism of Baricitinib can be increased when combined with Secobarbital. |
Lofexidine | Lofexidine The therapeutic efficacy of Secobarbital can be increased when used in combination with Lofexidine. |
Plazomicin Injection | Plazomicin Injection Secobarbital may decrease the excretion rate of Plazomicin which could result in a higher serum level. |
Binimetinib | Binimetinib The metabolism of Binimetinib can be increased when combined with Secobarbital. |
Ivosidenib | Ivosidenib The metabolism of Ivosidenib can be increased when combined with Secobarbital. |
Elagolix | Elagolix The metabolism of Elagolix can be increased when combined with Secobarbital. |
Cannabidiol | Cannabidiol The risk or severity of adverse effects can be increased when Cannabidiol is combined with Secobarbital. |
Dacomitinib | Dacomitinib The metabolism of Dacomitinib can be increased when combined with Secobarbital. |
Duvelisib | Duvelisib The metabolism of Duvelisib can be increased when combined with Secobarbital. |
Stiripentol | Stiripentol The risk or severity of adverse effects can be increased when Secobarbital is combined with Stiripentol. |
Gilteritinib | Gilteritinib The metabolism of Gilteritinib can be increased when combined with Secobarbital. |
Glasdegib | Glasdegib The metabolism of Glasdegib can be increased when combined with Secobarbital. |
Lorlatinib | Lorlatinib The metabolism of Lorlatinib can be increased when combined with Secobarbital. |
Paclitaxel (with albumin) Injection | Paclitaxel (with albumin) Injection The metabolism of Paclitaxel can be increased when combined with Secobarbital. |
Prucalopride | Prucalopride The metabolism of Prucalopride can be increased when combined with Secobarbital. |
Magnesium Citrate | Magnesium Citrate The therapeutic efficacy of Magnesium citrate can be decreased when used in combination with Secobarbital. |
Siponimod | Siponimod The metabolism of Siponimod can be increased when combined with Secobarbital. |
Acyclovir Ophthalmic | Acyclovir Ophthalmic Acyclovir may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Erdafitinib | Erdafitinib The metabolism of Erdafitinib can be increased when combined with Secobarbital. |
Alpelisib | Alpelisib The metabolism of Alpelisib can be increased when combined with Secobarbital. |
Brexanolone Injection | Brexanolone Injection The risk or severity of adverse effects can be increased when Secobarbital is combined with Brexanolone. |
Solriamfetol | Solriamfetol The risk or severity of adverse effects can be increased when Secobarbital is combined with Solriamfetol. |
Triclabendazole | Triclabendazole The metabolism of Triclabendazole can be increased when combined with Secobarbital. |
Entrectinib | Entrectinib The metabolism of Entrectinib can be increased when combined with Secobarbital. |
Pexidartinib | Pexidartinib The metabolism of Pexidartinib can be increased when combined with Secobarbital. |
Istradefylline | Istradefylline The metabolism of Istradefylline can be increased when combined with Secobarbital. |
Pitolisant | Pitolisant Secobarbital may decrease the excretion rate of Pitolisant which could result in a higher serum level. |
Lefamulin | Lefamulin The metabolism of Lefamulin can be increased when combined with Secobarbital. |
Phenytoin Injection | Phenytoin Injection The metabolism of Phenytoin can be increased when combined with Secobarbital. |
Fosphenytoin Injection | Fosphenytoin Injection The metabolism of Fosphenytoin can be increased when combined with Secobarbital. |
Zanubrutinib | Zanubrutinib The metabolism of Zanubrutinib can be increased when combined with Secobarbital. |
Lumateperone | Lumateperone The serum concentration of Lumateperone can be decreased when it is combined with Secobarbital. |
Lasmiditan | Lasmiditan The risk or severity of adverse effects can be increased when Secobarbital is combined with Lasmiditan. |
Tazemetostat | Tazemetostat The metabolism of Tazemetostat can be increased when combined with Secobarbital. |
Ozanimod | Ozanimod The metabolism of Ozanimod can be increased when combined with Secobarbital. |
Selumetinib | Selumetinib The metabolism of Selumetinib can be increased when combined with Secobarbital. |
Rimegepant | Rimegepant The metabolism of Rimegepant can be increased when combined with Secobarbital. |
Tucatinib | Tucatinib The metabolism of Tucatinib can be increased when combined with Secobarbital. |
Selpercatinib | Selpercatinib The serum concentration of Selpercatinib can be decreased when it is combined with Secobarbital. |
Capmatinib | Capmatinib The serum concentration of Capmatinib can be decreased when it is combined with Secobarbital. |
Lemborexant | Lemborexant The serum concentration of Lemborexant can be decreased when it is combined with Secobarbital. |
Fenfluramine | Fenfluramine The risk or severity of adverse effects can be increased when Secobarbital is combined with Fenfluramine. |
Progestin-Only (drospirenone) Oral Contraceptives | Progestin-Only (drospirenone) Oral Contraceptives The metabolism of Drospirenone can be increased when combined with Secobarbital. |
Viloxazine | Viloxazine The risk or severity of adverse effects can be increased when Secobarbital is combined with Viloxazine. |
Tobramycin Injection | Tobramycin Injection Tobramycin may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Theophylline | Theophylline The metabolism of Theophylline can be increased when combined with Secobarbital. |
Fenoprofen | Fenoprofen Fenoprofen may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Indomethacin | Indomethacin Indomethacin may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Mefenamic Acid | Mefenamic Acid Mefenamic acid may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Naproxen | Naproxen The metabolism of Naproxen can be increased when combined with Secobarbital. |
Tolmetin | Tolmetin Tolmetin may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Sulindac | Sulindac Sulindac may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Trazodone | Trazodone The risk or severity of adverse effects can be increased when Secobarbital is combined with Trazodone. |
Isotretinoin | Isotretinoin Secobarbital may decrease the excretion rate of Isotretinoin which could result in a higher serum level. |
Sucralfate | Sucralfate Sucralfate may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Floxuridine | Floxuridine Floxuridine may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Phenobarbital | Phenobarbital The metabolism of Phenobarbital can be increased when combined with Secobarbital. |
Metaxalone | Metaxalone The risk or severity of adverse effects can be increased when Secobarbital is combined with Metaxalone. |
Methotrexate Injection | Methotrexate Injection The metabolism of Secobarbital can be increased when combined with Methotrexate. |
Levorphanol | Levorphanol The risk or severity of adverse effects can be increased when Secobarbital is combined with Levorphanol. |
Primidone | Primidone The risk or severity of adverse effects can be increased when Primidone is combined with Secobarbital. |
Methsuximide | Methsuximide The risk or severity of adverse effects can be increased when Secobarbital is combined with Methsuximide. |
Diethylpropion | Diethylpropion The risk or severity of adverse effects can be increased when Secobarbital is combined with Diethylpropion. |
Chlorpromazine | Chlorpromazine The metabolism of Secobarbital can be increased when combined with Chlorpromazine. |
Diazepam | Diazepam The risk or severity of adverse effects can be increased when Secobarbital is combined with Diazepam. |
Oxazepam | Oxazepam The risk or severity of adverse effects can be increased when Secobarbital is combined with Oxazepam. |
Flurazepam | Flurazepam The risk or severity of adverse effects can be increased when Secobarbital is combined with Flurazepam. |
Clorazepate | Clorazepate The risk or severity of adverse effects can be increased when Secobarbital is combined with Clorazepic acid. |
Lorazepam | Lorazepam The risk or severity of adverse effects can be increased when Lorazepam is combined with Secobarbital. |
Phenoxybenzamine | Phenoxybenzamine Secobarbital may increase the hypotensive activities of Phenoxybenzamine. |
Carmustine | Carmustine The metabolism of Secobarbital can be increased when combined with Carmustine. |
Amantadine | Amantadine Secobarbital may decrease the excretion rate of Amantadine which could result in a higher serum level. |
Codeine | Codeine The risk or severity of adverse effects can be increased when Secobarbital is combined with Codeine. |
Meprobamate | Meprobamate The risk or severity of adverse effects can be increased when Meprobamate is combined with Secobarbital. |
Chlordiazepoxide | Chlordiazepoxide The risk or severity of adverse effects can be increased when Secobarbital is combined with Chlordiazepoxide. |
Bromocriptine | Bromocriptine The risk or severity of adverse effects can be increased when Secobarbital is combined with Bromocriptine. |
Tranylcypromine | Tranylcypromine Secobarbital may increase the hypotensive activities of Tranylcypromine. |
Phenelzine | Phenelzine Secobarbital may increase the hypotensive activities of Phenelzine. |
Procarbazine | Procarbazine The risk or severity of adverse effects can be increased when Secobarbital is combined with Procarbazine. |
Ergoloid Mesylates | Ergoloid Mesylates The risk or severity of adverse effects can be increased when Secobarbital is combined with Ergoloid mesylate. |
Tetracycline | Tetracycline Secobarbital may decrease the excretion rate of Tetracycline which could result in a higher serum level. |
Minocycline | Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Secobarbital. |
Prochlorperazine | Prochlorperazine The risk or severity of adverse effects can be increased when Secobarbital is combined with Prochlorperazine. |
Thioridazine | Thioridazine The risk or severity of adverse effects can be increased when Secobarbital is combined with Thioridazine. |
Trifluoperazine | Trifluoperazine The risk or severity of adverse effects can be increased when Secobarbital is combined with Trifluoperazine. |
Bleomycin | Bleomycin Bleomycin may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Dapsone | Dapsone The metabolism of Dapsone can be increased when combined with Secobarbital. |
Sulfadiazine | Sulfadiazine The metabolism of Sulfadiazine can be increased when combined with Secobarbital. |
Oxycodone | Oxycodone The risk or severity of adverse effects can be increased when Secobarbital is combined with Oxycodone. |
Methadone | Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Secobarbital. |
Oxybutynin | Oxybutynin Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Oxybutynin. |
Benztropine | Benztropine Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Benzatropine. |
Maprotiline | Maprotiline Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Maprotiline. |
Ibuprofen | Ibuprofen The metabolism of Ibuprofen can be increased when combined with Secobarbital. |
Trihexyphenidyl | Trihexyphenidyl Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Trihexyphenidyl. |
Orphenadrine | Orphenadrine Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine. |
Perphenazine | Perphenazine The metabolism of Perphenazine can be increased when combined with Secobarbital. |
Azathioprine | Azathioprine The metabolism of Azathioprine can be increased when combined with Secobarbital. |
Fluphenazine | Fluphenazine The risk or severity of adverse effects can be increased when Secobarbital is combined with Fluphenazine. |
Phentermine | Phentermine The metabolism of Phentermine can be increased when combined with Secobarbital. |
Methylphenidate | Methylphenidate The therapeutic efficacy of Methylphenidate can be decreased when used in combination with Secobarbital. |
Amoxapine | Amoxapine The metabolism of Amoxapine can be increased when combined with Secobarbital. |
Sulfasalazine | Sulfasalazine Sulfasalazine may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Doxorubicin | Doxorubicin The metabolism of Doxorubicin can be increased when combined with Secobarbital. |
Mechlorethamine | Mechlorethamine The therapeutic efficacy of Secobarbital can be decreased when used in combination with Mechlorethamine. |
Pyridostigmine | Pyridostigmine The therapeutic efficacy of Secobarbital can be decreased when used in combination with Pyridostigmine. |
Phenazopyridine | Phenazopyridine Phenazopyridine may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Carbamazepine | Carbamazepine Carbamazepine may increase the Change in thyroid function activities of Secobarbital. |
Molindone | Molindone The risk or severity of adverse effects can be increased when Secobarbital is combined with Molindone. |
Methyldopa | Methyldopa Secobarbital may increase the hypotensive activities of Methyldopa. |
Clonidine | Clonidine The risk or severity of sedation can be increased when Clonidine is combined with Secobarbital. |
Prazosin | Prazosin Secobarbital may increase the hypotensive activities of Prazosin. |
Hydralazine | Hydralazine Secobarbital may increase the hypotensive activities of Hydralazine. |
Cimetidine | Cimetidine Secobarbital may decrease the excretion rate of Cimetidine which could result in a higher serum level. |
Gentamicin Injection | Gentamicin Injection Gentamicin may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Warfarin | Warfarin The metabolism of Warfarin can be increased when combined with Secobarbital. |
Clonazepam | Clonazepam The metabolism of Clonazepam can be increased when combined with Secobarbital. |
Loperamide | Loperamide The metabolism of Loperamide can be increased when combined with Secobarbital. |
Promethazine | Promethazine The risk or severity of adverse effects can be increased when Secobarbital is combined with Promethazine. |
Meclofenamate | Meclofenamate Meclofenamic acid may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Nitrofurantoin | Nitrofurantoin Secobarbital may decrease the excretion rate of Nitrofurantoin which could result in a higher serum level. |
Griseofulvin | Griseofulvin The serum concentration of Griseofulvin can be decreased when it is combined with Secobarbital. |
Digoxin | Digoxin Secobarbital may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Loxapine | Loxapine The risk or severity of adverse effects can be increased when Loxapine is combined with Secobarbital. |
Chloroquine | Chloroquine The metabolism of Chloroquine can be increased when combined with Secobarbital. |
Quinine | Quinine The metabolism of Quinine can be increased when combined with Secobarbital. |
Ethosuximide | Ethosuximide The risk or severity of adverse effects can be increased when Secobarbital is combined with Ethosuximide. |
Triamterene | Triamterene Secobarbital may increase the hypotensive activities of Triamterene. |
Lactulose | Lactulose The therapeutic efficacy of Lactulose can be decreased when used in combination with Secobarbital. |
Chlorothiazide | Chlorothiazide The risk or severity of hypotension and orthostatic hypotension can be increased when Secobarbital is combined with Chlorothiazide. |
Chlorthalidone | Chlorthalidone The risk or severity of hypotension and orthostatic hypotension can be increased when Secobarbital is combined with Chlorthalidone. |
Metolazone | Metolazone The risk or severity of hypotension and orthostatic hypotension can be increased when Secobarbital is combined with Metolazone. |
Isosorbide | Isosorbide The metabolism of Isosorbide can be increased when combined with Secobarbital. |
Clindamycin Injection | Clindamycin Injection The metabolism of Clindamycin can be increased when combined with Secobarbital. |
Desipramine | Desipramine Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Desipramine. |
Amitriptyline | Amitriptyline The metabolism of Amitriptyline can be increased when combined with Secobarbital. |
Imipramine | Imipramine The metabolism of Imipramine can be increased when combined with Secobarbital. |
Probenecid | Probenecid Secobarbital may decrease the excretion rate of Probenecid which could result in a higher serum level. |
Quinidine | Quinidine The metabolism of Quinidine can be increased when combined with Secobarbital. |
Procainamide | Procainamide Procainamide may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Isoniazid | Isoniazid The therapeutic efficacy of Isoniazid can be decreased when used in combination with Secobarbital. |
Pyrazinamide | Pyrazinamide Pyrazinamide may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Disopyramide | Disopyramide Disopyramide may increase the central nervous system depressant (CNS depressant) activities of Secobarbital. |
Valproic Acid | Valproic Acid The serum concentration of Secobarbital can be increased when it is combined with Valproic acid. |
Tamoxifen | Tamoxifen The metabolism of Tamoxifen can be increased when combined with Secobarbital. |
Butabarbital | Butabarbital The risk or severity of adverse effects can be increased when Butabarbital is combined with Secobarbital. |
Liothyronine | Liothyronine Liothyronine may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Methimazole | Methimazole Secobarbital may decrease the excretion rate of Methimazole which could result in a higher serum level. |
Chlorpropamide | Chlorpropamide Secobarbital may decrease the excretion rate of Chlorpropamide which could result in a higher serum level. |
Tolbutamide | Tolbutamide The metabolism of Tolbutamide can be increased when combined with Secobarbital. |
Tolazamide | Tolazamide Secobarbital may decrease the excretion rate of Tolazamide which could result in a higher serum level. |
Dextromethorphan | Dextromethorphan The risk or severity of adverse effects can be increased when Secobarbital is combined with Dextromethorphan. |
Cyclobenzaprine | Cyclobenzaprine The risk or severity of CNS depression can be increased when Secobarbital is combined with Cyclobenzaprine. |
Baclofen | Baclofen The risk or severity of adverse effects can be increased when Baclofen is combined with Secobarbital. |
Doxylamine | Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Secobarbital. |
Cyproheptadine | Cyproheptadine Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Cyproheptadine. |
Clemastine | Clemastine The risk or severity of adverse effects can be increased when Clemastine is combined with Secobarbital. |
Chlorpheniramine | Chlorpheniramine The risk or severity of adverse effects can be increased when Secobarbital is combined with Chlorpheniramine. |
Brompheniramine | Brompheniramine The risk or severity of adverse effects can be increased when Dexbrompheniramine is combined with Secobarbital. |
Meclizine | Meclizine The risk or severity of adverse effects can be increased when Secobarbital is combined with Meclizine. |
Ethambutol | Ethambutol Ethambutol may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Methyclothiazide | Methyclothiazide The risk or severity of hypotension and orthostatic hypotension can be increased when Secobarbital is combined with Methyclothiazide. |
Hydrochlorothiazide | Hydrochlorothiazide The risk or severity of hypotension and orthostatic hypotension can be increased when Secobarbital is combined with Hydrochlorothiazide. |
Dantrolene | Dantrolene The risk or severity of adverse effects can be increased when Secobarbital is combined with Dantrolene. |
Chlorzoxazone | Chlorzoxazone The risk or severity of adverse effects can be increased when Chlorzoxazone is combined with Secobarbital. |
Carisoprodol | Carisoprodol The risk or severity of adverse effects can be increased when Carisoprodol is combined with Secobarbital. |
Methocarbamol | Methocarbamol The risk or severity of adverse effects can be increased when Secobarbital is combined with Methocarbamol. |
Pyridoxine | Pyridoxine The metabolism of Secobarbital can be increased when combined with Pyridoxine. |
Folic Acid | Folic Acid Folic acid may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Disulfiram | Disulfiram The therapeutic efficacy of Secobarbital can be decreased when used in combination with Disulfiram. |
Propranolol (Cardiovascular) | Propranolol (Cardiovascular) The serum concentration of Propranolol can be decreased when it is combined with Secobarbital. |
Minoxidil | Minoxidil Secobarbital may increase the hypotensive activities of Minoxidil. |
Nortriptyline | Nortriptyline The metabolism of Nortriptyline can be increased when combined with Secobarbital. |
Spironolactone | Spironolactone Secobarbital may increase the hypotensive activities of Spironolactone. |
Amphotericin B Injection | Amphotericin B Injection Secobarbital may increase the hypotensive activities of Amphotericin B. |
Mercaptopurine | Mercaptopurine The serum concentration of Mercaptopurine can be decreased when it is combined with Secobarbital. |
Phytonadione | Phytonadione Secobarbital may decrease the excretion rate of Phylloquinone which could result in a higher serum level. |
Amikacin Injection | Amikacin Injection Amikacin may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Nadolol | Nadolol The serum concentration of Nadolol can be decreased when it is combined with Secobarbital. |
Butorphanol Injection | Butorphanol Injection The risk or severity of adverse effects can be increased when Secobarbital is combined with Butorphanol. |
Nalbuphine Injection | Nalbuphine Injection The risk or severity of adverse effects can be increased when Secobarbital is combined with Nalbuphine. |
Allopurinol | Allopurinol Secobarbital may decrease the excretion rate of Allopurinol which could result in a higher serum level. |
Trimethobenzamide | Trimethobenzamide The risk or severity of adverse effects can be increased when Secobarbital is combined with Trimethobenzamide. |
Flavoxate | Flavoxate Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Flavoxate. |
Papaverine | Papaverine Secobarbital may increase the hypotensive activities of Papaverine. |
Fluorouracil Injection | Fluorouracil Injection The metabolism of Fluorouracil can be increased when combined with Secobarbital. |
Colchicine | Colchicine Secobarbital may decrease the excretion rate of Colchicine which could result in a higher serum level. |
Cefaclor | Cefaclor Cefaclor may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Cefadroxil | Cefadroxil Cefadroxil may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Cefazolin Injection | Cefazolin Injection Cefazolin may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Cephalexin | Cephalexin Cephalexin may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Cefoxitin Injection | Cefoxitin Injection Cefoxitin may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Dacarbazine | Dacarbazine The metabolism of Dacarbazine can be increased when combined with Secobarbital. |
Acetazolamide | Acetazolamide The risk or severity of adverse effects can be increased when Secobarbital is combined with Acetazolamide. |
Cefotaxime Injection | Cefotaxime Injection Cefotaxime may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Calcitonin Salmon Injection | Calcitonin Salmon Injection Salmon calcitonin may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Pyrantel | Pyrantel The risk or severity of adverse effects can be increased when Secobarbital is combined with Pyrantel. |
Thiotepa Injection | Thiotepa Injection The metabolism of Secobarbital can be increased when combined with Thiotepa. |
Vincristine Injection | Vincristine Injection The metabolism of Vincristine can be increased when combined with Secobarbital. |
Captopril | Captopril Secobarbital may increase the hypotensive activities of Captopril. |
Dipyridamole | Dipyridamole Secobarbital may increase the hypotensive activities of Dipyridamole. |
Isoxsuprine | Isoxsuprine Secobarbital may increase the hypotensive activities of Isoxsuprine. |
Vinblastine | Vinblastine The metabolism of Vinblastine can be increased when combined with Secobarbital. |
Ethacrynic Acid | Ethacrynic Acid Secobarbital may increase the hypotensive activities of Etacrynic acid. |
Colistimethate Injection | Colistimethate Injection Colistimethate may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Metoprolol | Metoprolol The serum concentration of Metoprolol can be decreased when it is combined with Secobarbital. |
Hydroxyzine | Hydroxyzine Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Secobarbital. |
Thiothixene | Thiothixene The risk or severity of adverse effects can be increased when Secobarbital is combined with Thiothixene. |
Aspirin | Aspirin Acetylsalicylic acid may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Salsalate | Salsalate Salsalate may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Chlorambucil | Chlorambucil The therapeutic efficacy of Secobarbital can be decreased when used in combination with Chlorambucil. |
Alprazolam | Alprazolam The risk or severity of adverse effects can be increased when Alprazolam is combined with Secobarbital. |
Temazepam | Temazepam The risk or severity of adverse effects can be increased when Temazepam is combined with Secobarbital. |
Triazolam | Triazolam The risk or severity of adverse effects can be increased when Secobarbital is combined with Triazolam. |
Dicyclomine | Dicyclomine Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Dicyclomine. |
Hyoscyamine | Hyoscyamine Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Hyoscyamine. |
Propantheline | Propantheline Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Propantheline. |
Trimethoprim | Trimethoprim Secobarbital may decrease the excretion rate of Trimethoprim which could result in a higher serum level. |
Diltiazem | Diltiazem The metabolism of Diltiazem can be increased when combined with Secobarbital. |
Nifedipine | Nifedipine The metabolism of Nifedipine can be increased when combined with Secobarbital. |
Timolol | Timolol The serum concentration of Timolol can be decreased when it is combined with Secobarbital. |
Verapamil | Verapamil The metabolism of Verapamil can be increased when combined with Secobarbital. |
Atenolol | Atenolol The serum concentration of Atenolol can be decreased when it is combined with Secobarbital. |
Pindolol | Pindolol The serum concentration of Pindolol can be decreased when it is combined with Secobarbital. |
Cisplatin Injection | Cisplatin Injection Cisplatin may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Diflunisal | Diflunisal Diflunisal may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Piroxicam | Piroxicam The metabolism of Piroxicam can be increased when combined with Secobarbital. |
Bumetanide | Bumetanide Secobarbital may increase the hypotensive activities of Bumetanide. |
Etoposide | Etoposide The metabolism of Etoposide can be increased when combined with Secobarbital. |
Glipizide | Glipizide Secobarbital may decrease the excretion rate of Glipizide which could result in a higher serum level. |
Indapamide | Indapamide The risk or severity of hypotension and orthostatic hypotension can be increased when Secobarbital is combined with Indapamide. |
Amoxicillin | Amoxicillin Secobarbital may decrease the excretion rate of Amoxicillin which could result in a higher serum level. |
Oxacillin Injection | Oxacillin Injection Secobarbital may decrease the excretion rate of Oxacillin which could result in a higher serum level. |
Pentoxifylline | Pentoxifylline The serum concentration of Pentoxifylline can be decreased when it is combined with Secobarbital. |
Pentamidine Injection | Pentamidine Injection Pentamidine may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Ceftriaxone Injection | Ceftriaxone Injection Ceftriaxone may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Labetalol | Labetalol The serum concentration of Labetalol can be decreased when it is combined with Secobarbital. |
Auranofin | Auranofin Secobarbital may decrease the excretion rate of Auranofin which could result in a higher serum level. |
Leuprolide Injection | Leuprolide Injection Leuprolide may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Gemfibrozil | Gemfibrozil Secobarbital may decrease the excretion rate of Gemfibrozil which could result in a higher serum level. |
Guanabenz | Guanabenz The metabolism of Guanabenz can be increased when combined with Secobarbital. |
Dipivefrin Ophthalmic | Dipivefrin Ophthalmic Adefovir dipivoxil may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Ceftazidime Injection | Ceftazidime Injection Ceftazidime may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Ketoprofen | Ketoprofen Ketoprofen may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Cefotetan Injection | Cefotetan Injection Cefotetan may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Pimozide | Pimozide The metabolism of Pimozide can be increased when combined with Secobarbital. |
Enalapril | Enalapril Secobarbital may increase the hypotensive activities of Enalapril. |
Flurbiprofen | Flurbiprofen Flurbiprofen may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Amiodarone | Amiodarone The metabolism of Amiodarone can be increased when combined with Secobarbital. |
Aztreonam Injection | Aztreonam Injection Aztreonam may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Buspirone | Buspirone Secobarbital may decrease the excretion rate of Buspirone which could result in a higher serum level. |
Lovastatin | Lovastatin The metabolism of Lovastatin can be increased when combined with Secobarbital. |
Ciprofloxacin | Ciprofloxacin Secobarbital may decrease the excretion rate of Ciprofloxacin which could result in a higher serum level. |
Mesalamine | Mesalamine Mesalazine may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Diclofenac | Diclofenac The metabolism of Diclofenac can be increased when combined with Secobarbital. |
Fluoxetine | Fluoxetine Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine. |
Nimodipine | Nimodipine The metabolism of Nimodipine can be increased when combined with Secobarbital. |
Clozapine | Clozapine Clozapine may increase the central nervous system depressant (CNS depressant) activities of Secobarbital. |
Estazolam | Estazolam The risk or severity of adverse effects can be increased when Secobarbital is combined with Estazolam. |
Didanosine | Didanosine Secobarbital may decrease the excretion rate of Didanosine which could result in a higher serum level. |
Pentostatin Injection | Pentostatin Injection Secobarbital may decrease the excretion rate of Pentostatin which could result in a higher serum level. |
Benazepril | Benazepril Secobarbital may increase the hypotensive activities of Benazepril. |
Etodolac | Etodolac Etodolac may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Felodipine | Felodipine Secobarbital may increase the hypotensive activities of Felodipine. |
Fosinopril | Fosinopril Secobarbital may increase the hypotensive activities of Fosinopril. |
Nabumetone | Nabumetone Nabumetone may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Quinapril | Quinapril Secobarbital may increase the hypotensive activities of Quinapril. |
Ramipril | Ramipril Ramipril may increase the hypotensive activities of Secobarbital. |
Simvastatin | Simvastatin The metabolism of Simvastatin can be increased when combined with Secobarbital. |
Amlodipine | Amlodipine The metabolism of Amlodipine can be increased when combined with Secobarbital. |
Teniposide Injection | Teniposide Injection The serum concentration of Teniposide can be decreased when it is combined with Secobarbital. |
Lisinopril | Lisinopril Secobarbital may increase the hypotensive activities of Lisinopril. |
Oxaprozin | Oxaprozin Oxaprozin may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Sotalol | Sotalol The serum concentration of Sotalol can be decreased when it is combined with Secobarbital. |
Bisoprolol | Bisoprolol The serum concentration of Bisoprolol can be decreased when it is combined with Secobarbital. |
Zolpidem | Zolpidem Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Zolpidem. |
Doxazosin | Doxazosin Secobarbital may increase the hypotensive activities of Doxazosin. |
Terazosin | Terazosin Secobarbital may increase the hypotensive activities of Terazosin. |
Isradipine | Isradipine The metabolism of Isradipine can be increased when combined with Secobarbital. |
Omeprazole | Omeprazole The metabolism of Omeprazole can be increased when combined with Secobarbital. |
Cisapride | Cisapride The metabolism of Cisapride can be increased when combined with Secobarbital. |
Gabapentin | Gabapentin The risk or severity of adverse effects can be increased when Secobarbital is combined with Gabapentin. |
Fluvastatin | Fluvastatin The metabolism of Fluvastatin can be increased when combined with Secobarbital. |
Venlafaxine | Venlafaxine The risk or severity of adverse effects can be increased when Venlafaxine is combined with Secobarbital. |
Nizatidine | Nizatidine The therapeutic efficacy of Secobarbital can be decreased when used in combination with Nizatidine. |
Famciclovir | Famciclovir The metabolism of Famciclovir can be increased when combined with Secobarbital. |
Fluvoxamine | Fluvoxamine The risk or severity of adverse effects can be increased when Secobarbital is combined with Fluvoxamine. |
Nefazodone | Nefazodone The risk or severity of adverse effects can be increased when Secobarbital is combined with Nefazodone. |
Lamotrigine | Lamotrigine The serum concentration of Lamotrigine can be decreased when it is combined with Secobarbital. |
Losartan | Losartan Secobarbital may increase the hypotensive activities of Losartan. |
Valacyclovir | Valacyclovir Valaciclovir may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Tramadol | Tramadol The metabolism of Tramadol can be increased when combined with Secobarbital. |
Vinorelbine Injection | Vinorelbine Injection The metabolism of Vinorelbine can be increased when combined with Secobarbital. |
Carboplatin Injection | Carboplatin Injection Carboplatin may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Moexipril | Moexipril Secobarbital may increase the hypotensive activities of Moexipril. |
Lansoprazole | Lansoprazole The metabolism of Lansoprazole can be increased when combined with Secobarbital. |
Ifosfamide Injection | Ifosfamide Injection The metabolism of Ifosfamide can be increased when combined with Secobarbital. |
Nicardipine | Nicardipine The metabolism of Nicardipine can be increased when combined with Secobarbital. |
Bupropion | Bupropion The risk or severity of adverse effects can be increased when Secobarbital is combined with Bupropion. |
Ticlopidine | Ticlopidine The metabolism of Secobarbital can be increased when combined with Ticlopidine. |
Metformin | Metformin Metformin may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Nisoldipine | Nisoldipine Secobarbital may increase the hypotensive activities of Nisoldipine. |
Lamivudine | Lamivudine Secobarbital may decrease the excretion rate of Lamivudine which could result in a higher serum level. |
Riluzole | Riluzole The risk or severity of adverse effects can be increased when Secobarbital is combined with Riluzole. |
Amifostine Injection | Amifostine Injection Secobarbital may increase the hypotensive activities of Amifostine. |
Acarbose | Acarbose Acarbose may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Anastrozole | Anastrozole The metabolism of Anastrozole can be increased when combined with Secobarbital. |
Gemcitabine Injection | Gemcitabine Injection Secobarbital may decrease the excretion rate of Gemcitabine which could result in a higher serum level. |
Docetaxel Injection | Docetaxel Injection The metabolism of Docetaxel can be increased when combined with Secobarbital. |
Cidofovir Injection | Cidofovir Injection Cidofovir may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Meropenem Injection | Meropenem Injection Secobarbital may decrease the excretion rate of Meropenem which could result in a higher serum level. |
Clomipramine | Clomipramine The metabolism of Clomipramine can be increased when combined with Secobarbital. |
Zafirlukast | Zafirlukast The metabolism of Zafirlukast can be increased when combined with Secobarbital. |
Fosfomycin | Fosfomycin Secobarbital may decrease the excretion rate of Fosfomycin which could result in a higher serum level. |
Mirtazapine | Mirtazapine Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine. |
Trandolapril | Trandolapril Secobarbital may increase the hypotensive activities of Trandolapril. |
Topiramate | Topiramate The risk or severity of adverse effects can be increased when Topiramate is combined with Secobarbital. |
Zileuton | Zileuton The metabolism of Zileuton can be increased when combined with Secobarbital. |
Valsartan | Valsartan Secobarbital may increase the hypotensive activities of Valsartan. |
Pramipexole | Pramipexole Secobarbital may increase the sedative activities of Pramipexole. |
Donepezil | Donepezil The therapeutic efficacy of Secobarbital can be decreased when used in combination with Donepezil. |
Azithromycin | Azithromycin The metabolism of Azithromycin can be increased when combined with Secobarbital. |
Loratadine | Loratadine Secobarbital may increase the anticholinergic activities of Loratadine. |
Carvedilol | Carvedilol The serum concentration of Carvedilol can be decreased when it is combined with Secobarbital. |
Nilutamide | Nilutamide Secobarbital may decrease the excretion rate of Nilutamide which could result in a higher serum level. |
Flutamide | Flutamide The metabolism of Flutamide can be increased when combined with Secobarbital. |
Selegiline | Selegiline The metabolism of Selegiline can be increased when combined with Secobarbital. |
Bicalutamide | Bicalutamide The metabolism of Bicalutamide can be increased when combined with Secobarbital. |
Sertraline | Sertraline The risk or severity of adverse effects can be increased when Secobarbital is combined with Sertraline. |
Propafenone | Propafenone The serum concentration of Propafenone can be decreased when it is combined with Secobarbital. |
Irbesartan | Irbesartan The metabolism of Irbesartan can be increased when combined with Secobarbital. |
Tamsulosin | Tamsulosin Secobarbital may increase the hypotensive activities of Tamsulosin. |
Ropinirole | Ropinirole The metabolism of Ropinirole can be increased when combined with Secobarbital. |
Quetiapine | Quetiapine Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Quetiapine. |
Cefepime Injection | Cefepime Injection Cefepime may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Cefprozil | Cefprozil Cefprozil may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Cefpodoxime | Cefpodoxime Cefpodoxime may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Cetirizine | Cetirizine The risk or severity of adverse effects can be increased when Cetirizine is combined with Secobarbital. |
Paroxetine | Paroxetine The risk or severity of adverse effects can be increased when Secobarbital is combined with Paroxetine. |
Tolcapone | Tolcapone The risk or severity of adverse effects can be increased when Tolcapone is combined with Secobarbital. |
Citalopram | Citalopram The risk or severity of adverse effects can be increased when Secobarbital is combined with Citalopram. |
Capecitabine | Capecitabine The metabolism of Capecitabine can be increased when combined with Secobarbital. |
Efavirenz | Efavirenz The risk or severity of adverse effects can be increased when Secobarbital is combined with Efavirenz. |
Abacavir | Abacavir Secobarbital may decrease the excretion rate of Abacavir which could result in a higher serum level. |
Pioglitazone | Pioglitazone The metabolism of Pioglitazone can be increased when combined with Secobarbital. |
Celecoxib | Celecoxib The metabolism of Celecoxib can be increased when combined with Secobarbital. |
Rosiglitazone | Rosiglitazone The metabolism of Rosiglitazone can be increased when combined with Secobarbital. |
Tolterodine | Tolterodine Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Thalidomide | Thalidomide Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Thalidomide. |
Oseltamivir | Oseltamivir Oseltamivir may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Balsalazide | Balsalazide Balsalazide may decrease the excretion rate of Secobarbital which could result in a higher serum level. |
Nateglinide | Nateglinide Secobarbital may decrease the excretion rate of Nateglinide which could result in a higher serum level. |
Galantamine | Galantamine The therapeutic efficacy of Secobarbital can be decreased when used in combination with Galantamine. |
Levetiracetam | Levetiracetam The risk or severity of adverse effects can be increased when Secobarbital is combined with Levetiracetam. |
Rabeprazole | Rabeprazole Secobarbital may decrease the excretion rate of Rabeprazole which could result in a higher serum level. |
Terbinafine | Terbinafine The metabolism of Terbinafine can be increased when combined with Secobarbital. |
Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists