Secobarbital

Generic name: Pronounced as (see koe bar' bi tal)
Brand names
  • Seconal®
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Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 06/15/2017

Secobarbital is used on a short-term basis to treat insomnia (difficulty falling asleep or staying asleep). It is also used to relieve anxiety before surgery. Secobarbital is in a class of medications called barbiturates. It works by slowing activity in the brain.

Secobarbital comes as a capsule to take by mouth. When secobarbital is used to treat insomnia, it is usually taken at bedtime as needed for sleep. When secobarbital is used to relieve anxiety before surgery, it is usually taken 1 to 2 hours before surgery. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take secobarbital exactly as directed.

Your sleep problems should improve within 7 to 10 days after you start taking secobarbital. Call your doctor if your sleep problems do not improve during this time, if they get worse at any time during your treatment, or if you notice any changes in your thoughts or behavior.

Secobarbital should normally be taken for short periods of time. If you take secobarbital for 2 weeks or longer, secobarbital may not help you sleep as well as it did when you first began to take the medication. If you take secobarbital for a long time, you may also develop dependence ('addiction,' a need to continue taking the medication) on secobarbital. Talk to your doctor about the risks of taking secobarbital for 2 weeks or longer. Do not take a larger dose of secobarbital, take it more often, or take it for a longer time than prescribed by your doctor.

Do not stop taking secobarbital without talking to your doctor. Your doctor will probably decrease your dose gradually. If you suddenly stop taking secobarbital, you may develop anxiety, muscle twitching, uncontrollable shaking of your hands or fingers, weakness, dizziness, changes in vision, nausea, vomiting, or difficulty falling asleep or staying asleep, or you may experience more severe withdrawal symptoms such as seizures or extreme confusion.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking secobarbital,

  • tell your doctor and pharmacist if you are allergic to secobarbital; other barbiturates such as amobarbital (Amytal, in Tuinal), butabarbital (Butisol), pentobarbital, or phenobarbital; any other medications, or any of the ingredients in secobarbital capsules. Ask your pharmacist for a list of the ingredients.

  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: anticoagulants ('blood thinners') such as warfarin (Coumadin); antihistamines; doxycycline (Doryx, Vibramycin; Vibra-tabs); griseofulvin (Fulvicin-U/F, Grifulvin V, Gris-PEG ); hormone replacement therapy; monoamine oxidase (MAO) inhibitors such as isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate); medications for depression,pain, colds, or allergies; certain medictations for seizures such as phenytoin (Dilantin) and valproic acid (Depakene); muscle relaxants; oral steroids such as dexamethasone (Decadron, Dexone), methylprednisolone (Medrol), and prednisone (Deltasone); sedatives; sleeping pills; and tranquilizers. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

  • tell your doctor if you have or have ever had porphyria (condition in which certain natural substances build up in the body and may cause stomach pain, changes in thinking and behavior, and other symptoms); any condition that causes shortness of breath or difficulty breathing; or liver disease. Your doctor will probably tell you not to take secobarbital.

  • tell your doctor if you drink or have ever drunk large amounts of alcohol, use or have ever used street drugs, or have overused prescription medications.Also tell your doctor if you have ever thought about killing yourself or tried to do so and if you have or have ever had depression; pain; or kidney disease.

  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking secobarbital, call your doctor.

  • you should know that secobarbital may decrease the effectiveness of hormonal contraceptives (birth control pills, patches, rings, injections, implants, or intrauterine devices). Talk to your doctor about methods of birth control that will work for you while you are taking secobarbital. Tell your doctor if you have a missed period or think you may be pregnant while you are taking secobarbital.

  • talk to your doctor about the risks and benefits of taking this medication if you are 65 years of age or older. Older adults should not usually take secobarbital to treat conditions other than seizures because it is not as safe as other medications that can be used to treat the same conditions.

  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking secobarbital.

  • you should know that this medication may make you drowsy during the daytime. Do not drive a car or operate machinery until you know how this medication affects you.

  • do not drink alcohol during your treatment with secobarbital. Alcohol can make the side effects of secobarbital worse.

  • you should know that some people who took medications for sleep got out of bed and drove their cars, prepared and ate food, had sex, made phone calls, or were involved in other activities while partially asleep. After they woke up, these people were usually unable to remember what they had done. Call your doctor right away if you find out that you have been driving or doing anything else while you were sleeping.

Unless your doctor tells you otherwise, continue your normal diet.

Secobarbital is usually taken at bedtime. If you forget to take secobarbital at bedtime, you are unable to fall asleep, and you will still be able to stay in bed for a full night's sleep, you may take secobarbital at that time. Do not take a double dose of secobarbital to make up for a missed dose.

  • Secobarbital may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • drowsiness

    • difficulty falling asleep or staying asleep

    • nightmares

    • headache

    • dizziness

    • nervousness

    • agitation

    • excitement

    • restlessness

    • confusion

    • nausea

    • vomiting

    • diarrhea

    • constipation

  • Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:

    • hallucinating (seeing things or hearing voices that do not exist)

    • slow, shallow breathing

    • slow heartbeat

    • hives

    • rash

    • itching

    • swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs

    • difficulty breathing or swallowing

    • hoarseness

  • Secobarbital may cause other side effects. Tell your doctor if you have any unusual problems during your treatment with secobarbital.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Store secobarbital in a safe place so that no one else can take it accidentally or on purpose. Keep track of how many capsules are left so you will know if any are missing.

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Symptoms of overdose may include:

  • slowed breathing

  • low body temperature

Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your response to secobarbital.

This prescription is not refillable.

Do not let anyone else take your medication.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

  • quinalbarbitone sodium

Drug Interaction
Repaglinide Repaglinide The metabolism of Repaglinide can be increased when combined with Secobarbital.
Montelukast Montelukast The metabolism of Montelukast can be increased when combined with Secobarbital.
Leflunomide Leflunomide The metabolism of Leflunomide can be increased when combined with Secobarbital.
Atorvastatin Atorvastatin The metabolism of Atorvastatin can be increased when combined with Secobarbital.
Dolasetron Dolasetron The risk or severity of adverse effects can be increased when Secobarbital is combined with Dolasetron.
Aminophylline Aminophylline The therapeutic efficacy of Secobarbital can be decreased when used in combination with Aminophylline.
Anagrelide Anagrelide The metabolism of Anagrelide can be increased when combined with Secobarbital.
Bisacodyl Bisacodyl The therapeutic efficacy of Bisacodyl can be decreased when used in combination with Secobarbital.
Cilostazol Cilostazol The metabolism of Cilostazol can be increased when combined with Secobarbital.
Clopidogrel Clopidogrel The metabolism of Clopidogrel can be increased when combined with Secobarbital.
Diphenoxylate Diphenoxylate The risk or severity of adverse effects can be increased when Secobarbital is combined with Diphenoxylate.
Estrogen and Progestin (Oral Contraceptives) Estrogen and Progestin (Oral Contraceptives) The metabolism of Secobarbital can be increased when combined with Conjugated estrogens.
Fenofibrate Fenofibrate The metabolism of Fenofibrate can be increased when combined with Secobarbital.
Guanfacine Guanfacine The risk or severity of adverse effects can be increased when Secobarbital is combined with Guanfacine.
Magnesium Hydroxide Magnesium Hydroxide Secobarbital may decrease the excretion rate of Magnesium hydroxide which could result in a higher serum level.
Magnesium Oxide Magnesium Oxide The therapeutic efficacy of Magnesium oxide can be decreased when used in combination with Secobarbital.
Mycophenolate Mycophenolate Secobarbital may decrease the excretion rate of Mycophenolic acid which could result in a higher serum level.
Naratriptan Naratriptan The risk or severity of adverse effects can be increased when Secobarbital is combined with Naratriptan.
Olsalazine Olsalazine Olsalazine may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Paregoric Paregoric The risk or severity of adverse effects can be increased when Secobarbital is combined with Morphine.
Penbutolol Penbutolol The serum concentration of Acebutolol can be decreased when it is combined with Secobarbital.
Pentazocine Pentazocine The risk or severity of adverse effects can be increased when Secobarbital is combined with Pentazocine.
Polyethylene glycol-electrolyte solution (PEG-ES) Polyethylene glycol-electrolyte solution (PEG-ES) The therapeutic efficacy of Polyethylene glycol can be decreased when used in combination with Secobarbital.
Potassium Potassium Potassium may increase the excretion rate of Secobarbital which could result in a lower serum level and potentially a reduction in efficacy.
Prednisone Prednisone Secobarbital may decrease the excretion rate of Prednisone which could result in a higher serum level.
Psyllium Psyllium The therapeutic efficacy of Plantago seed can be decreased when used in combination with Secobarbital.
Ranitidine Ranitidine The metabolism of Ranitidine can be increased when combined with Secobarbital.
Reserpine Reserpine Secobarbital may increase the hypotensive activities of Reserpine.
Rizatriptan Rizatriptan The risk or severity of adverse effects can be increased when Secobarbital is combined with Rizatriptan.
Sumatriptan Sumatriptan The risk or severity of adverse effects can be increased when Secobarbital is combined with Sumatriptan.
Tacrolimus Tacrolimus The metabolism of Tacrolimus can be increased when combined with Secobarbital.
Tizanidine Tizanidine The metabolism of Tizanidine can be increased when combined with Secobarbital.
Zolmitriptan Zolmitriptan The metabolism of Zolmitriptan can be increased when combined with Secobarbital.
Ampicillin Injection Ampicillin Injection Ampicillin may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Doxycycline Injection Doxycycline Injection The serum concentration of Doxycycline can be decreased when it is combined with Secobarbital.
Fluconazole Injection Fluconazole Injection Fluconazole may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Foscarnet Injection Foscarnet Injection Foscarnet may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Hydromorphone Injection Hydromorphone Injection The risk or severity of adverse effects can be increased when Hydromorphone is combined with Secobarbital.
Levofloxacin Injection Levofloxacin Injection Secobarbital may decrease the excretion rate of Levofloxacin which could result in a higher serum level.
Meperidine Injection Meperidine Injection Secobarbital may increase the hypotensive and central nervous system depressant (CNS depressant) activities of Meperidine.
Metoclopramide Injection Metoclopramide Injection The risk or severity of sedation can be increased when Metoclopramide is combined with Secobarbital.
Metronidazole Injection Metronidazole Injection The therapeutic efficacy of Secobarbital can be decreased when used in combination with Metronidazole.
Morphine Injection Morphine Injection The risk or severity of adverse effects can be increased when Secobarbital is combined with Morphine.
Pamidronate Injection Pamidronate Injection Pamidronic acid may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Vancomycin Injection Vancomycin Injection Secobarbital may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Zidovudine Injection Zidovudine Injection The metabolism of Zidovudine can be increased when combined with Secobarbital.
Altretamine Altretamine The therapeutic efficacy of Secobarbital can be decreased when used in combination with Amphetamine.
Cefuroxime Cefuroxime Cefuroxime may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Cyclosporine Cyclosporine The metabolism of Cyclosporine can be increased when combined with Secobarbital.
Ondansetron Ondansetron The risk or severity of adverse effects can be increased when Secobarbital is combined with Ondansetron.
Granisetron Granisetron The risk or severity of adverse effects can be increased when Secobarbital is combined with Granisetron.
Torsemide Torsemide The metabolism of Torasemide can be increased when combined with Secobarbital.
Olanzapine Olanzapine The risk or severity of adverse effects can be increased when Olanzapine is combined with Secobarbital.
Alosetron Alosetron The metabolism of Alosetron can be increased when combined with Secobarbital.
Dofetilide Dofetilide The metabolism of Dofetilide can be increased when combined with Secobarbital.
Entacapone Entacapone The risk or severity of adverse effects can be increased when Secobarbital is combined with Entacapone.
Eprosartan Eprosartan Secobarbital may increase the hypotensive activities of Eprosartan.
Hydroxychloroquine Hydroxychloroquine The therapeutic efficacy of Hydroxychloroquine can be decreased when used in combination with Secobarbital.
Meloxicam Meloxicam Meloxicam may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Orlistat Orlistat Orlistat can cause a decrease in the absorption of Secobarbital resulting in a reduced serum concentration and potentially a decrease in efficacy.
Oxcarbazepine Oxcarbazepine The risk or severity of adverse effects can be increased when Secobarbital is combined with Oxcarbazepine.
Pantoprazole Pantoprazole Pantoprazole may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Telmisartan Telmisartan Secobarbital may increase the hypotensive activities of Telmisartan.
Temozolomide Temozolomide Secobarbital may decrease the excretion rate of Temozolomide which could result in a higher serum level.
Zaleplon Zaleplon The risk or severity of adverse effects can be increased when Secobarbital is combined with Zaleplon.
Desloratadine Desloratadine The risk or severity of adverse effects can be increased when Secobarbital is combined with Desloratadine.
Linezolid Linezolid The risk or severity of adverse effects can be increased when Secobarbital is combined with Linezolid.
Rivastigmine Rivastigmine The therapeutic efficacy of Secobarbital can be decreased when used in combination with Rivastigmine.
Trimipramine Trimipramine The metabolism of Trimipramine can be increased when combined with Secobarbital.
Glycopyrrolate Glycopyrrolate Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Glycopyrronium.
Perindopril Perindopril Perindopril may increase the hypotensive activities of Secobarbital.
Tenofovir Tenofovir Tenofovir may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Choline Magnesium Trisalicylate Choline Magnesium Trisalicylate Choline magnesium trisalicylate may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Sirolimus Sirolimus The metabolism of Sirolimus can be increased when combined with Secobarbital.
Eplerenone Eplerenone Secobarbital may increase the hypotensive activities of Eplerenone.
Escitalopram Escitalopram The risk or severity of adverse effects can be increased when Secobarbital is combined with Escitalopram.
Olmesartan Olmesartan Secobarbital may increase the hypotensive activities of Olmesartan.
Zonisamide Zonisamide The risk or severity of adverse effects can be increased when Secobarbital is combined with Zonisamide.
Aripiprazole Aripiprazole The metabolism of Aripiprazole can be increased when combined with Secobarbital.
Atomoxetine Atomoxetine The risk or severity of adverse effects can be increased when Atomoxetine is combined with Secobarbital.
Dexmethylphenidate Dexmethylphenidate The risk or severity of adverse effects can be increased when Secobarbital is combined with Dexmethylphenidate.
Atazanavir Atazanavir Atazanavir may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Almotriptan Almotriptan The metabolism of Almotriptan can be increased when combined with Secobarbital.
Eletriptan Eletriptan The risk or severity of adverse effects can be increased when Eletriptan is combined with Secobarbital.
Mefloquine Mefloquine The therapeutic efficacy of Secobarbital can be decreased when used in combination with Mefloquine.
Polyethylene Glycol 3350 Polyethylene Glycol 3350 The therapeutic efficacy of Polyethylene glycol can be decreased when used in combination with Secobarbital.
Rosuvastatin Rosuvastatin The metabolism of Rosuvastatin can be increased when combined with Secobarbital.
Emtricitabine Emtricitabine Secobarbital may decrease the excretion rate of Emtricitabine which could result in a higher serum level.
Memantine Memantine The therapeutic efficacy of Secobarbital can be decreased when used in combination with Memantine.
Tegaserod Tegaserod The therapeutic efficacy of Tegaserod can be decreased when used in combination with Secobarbital.
Tadalafil Tadalafil Secobarbital may decrease the excretion rate of Tadalafil which could result in a higher serum level.
Frovatriptan Frovatriptan The metabolism of Frovatriptan can be increased when combined with Secobarbital.
Progesterone Progesterone The metabolism of Progesterone can be increased when combined with Secobarbital.
Apomorphine Injection Apomorphine Injection The metabolism of Apomorphine can be increased when combined with Secobarbital.
Protriptyline Protriptyline The metabolism of Protriptyline can be increased when combined with Secobarbital.
Duloxetine Duloxetine The risk or severity of adverse effects can be increased when Secobarbital is combined with Duloxetine.
Norethindrone Norethindrone The metabolism of Norethisterone can be increased when combined with Secobarbital.
Tinidazole Tinidazole Secobarbital may decrease the excretion rate of Tinidazole which could result in a higher serum level.
Trospium Trospium Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Trospium.
Cefditoren Cefditoren Secobarbital may decrease the excretion rate of Cefdinir which could result in a higher serum level.
Cinacalcet Cinacalcet The metabolism of Cinacalcet can be increased when combined with Secobarbital.
Cyanocobalamin Injection Cyanocobalamin Injection Hydroxocobalamin may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Erlotinib Erlotinib The serum concentration of Erlotinib can be decreased when it is combined with Secobarbital.
Eszopiclone Eszopiclone The risk or severity of CNS depression can be increased when Secobarbital is combined with Eszopiclone.
Ganciclovir Ganciclovir The therapeutic efficacy of Ganciclovir can be decreased when used in combination with Secobarbital.
Ribavirin Ribavirin Secobarbital may decrease the excretion rate of Ribavirin which could result in a higher serum level.
Solifenacin Solifenacin Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Valganciclovir Valganciclovir The therapeutic efficacy of Valganciclovir can be decreased when used in combination with Secobarbital.
Voriconazole Voriconazole The serum concentration of Voriconazole can be decreased when it is combined with Secobarbital.
Adefovir Adefovir Adefovir may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Dextroamphetamine Dextroamphetamine The therapeutic efficacy of Secobarbital can be decreased when used in combination with Amphetamine.
Entecavir Entecavir The metabolism of Entecavir can be increased when combined with Secobarbital.
Sodium Oxybate Sodium Oxybate Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate.
Isocarboxazid Isocarboxazid Secobarbital may increase the hypotensive activities of Isocarboxazid.
Ramelteon Ramelteon The risk or severity of adverse effects can be increased when Secobarbital is combined with Ramelteon.
Darifenacin Darifenacin Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Darifenacin.
Fentanyl Fentanyl The risk or severity of adverse effects can be increased when Secobarbital is combined with Fentanyl.
Pregabalin Pregabalin The therapeutic efficacy of Secobarbital can be increased when used in combination with Pregabalin.
Felbamate Felbamate The serum concentration of Secobarbital can be increased when it is combined with Felbamate.
Ranolazine Ranolazine The metabolism of Secobarbital can be increased when combined with Ranolazine.
Rasagiline Rasagiline Secobarbital may increase the hypotensive activities of Rasagiline.
Imatinib Imatinib The metabolism of Imatinib can be increased when combined with Secobarbital.
Sitagliptin Sitagliptin The metabolism of Sitagliptin can be increased when combined with Secobarbital.
Varenicline Varenicline Secobarbital may decrease the excretion rate of Varenicline which could result in a higher serum level.
Albuterol Albuterol Secobarbital may decrease the excretion rate of Salbutamol which could result in a higher serum level.
Paliperidone Paliperidone The risk or severity of adverse effects can be increased when Secobarbital is combined with Paliperidone.
Bortezomib Bortezomib The metabolism of Bortezomib can be increased when combined with Secobarbital.
Clofarabine Injection Clofarabine Injection Secobarbital may increase the hypotensive activities of Clofarabine.
Lubiprostone Lubiprostone Secobarbital may decrease the excretion rate of Lubiprostone which could result in a higher serum level.
Primaquine Primaquine The metabolism of Primaquine can be increased when combined with Secobarbital.
Aliskiren Aliskiren Secobarbital may increase the hypotensive activities of Aliskiren.
Pemetrexed Injection Pemetrexed Injection Secobarbital may decrease the excretion rate of Pemetrexed which could result in a higher serum level.
Dimenhydrinate Dimenhydrinate The risk or severity of adverse effects can be increased when Secobarbital is combined with Dimenhydrinate.
Nabilone Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Secobarbital.
Retapamulin Retapamulin The metabolism of Retapamulin can be increased when combined with Secobarbital.
Sorafenib Sorafenib The metabolism of Sorafenib can be increased when combined with Secobarbital.
Sunitinib Sunitinib The metabolism of Sunitinib can be increased when combined with Secobarbital.
Dronabinol Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Secobarbital.
Lapatinib Lapatinib The metabolism of Lapatinib can be increased when combined with Secobarbital.
Levocetirizine Levocetirizine The risk or severity of adverse effects can be increased when Secobarbital is combined with Levocetirizine.
Pegaptanib Injection Pegaptanib Injection Secobarbital may decrease the excretion rate of Pegaptanib which could result in a higher serum level.
Dasatinib Dasatinib The metabolism of Dasatinib can be increased when combined with Secobarbital.
Mexiletine Mexiletine The metabolism of Mexiletine can be increased when combined with Secobarbital.
Azacitidine Injection Azacitidine Injection Secobarbital may decrease the excretion rate of Azacitidine which could result in a higher serum level.
Paclitaxel (with polyoxyethylated castor oil) Injection Paclitaxel (with polyoxyethylated castor oil) Injection The therapeutic efficacy of Castor oil can be decreased when used in combination with Secobarbital.
Temsirolimus Temsirolimus The metabolism of Temsirolimus can be increased when combined with Secobarbital.
Lenalidomide Lenalidomide Secobarbital may decrease the excretion rate of Lenalidomide which could result in a higher serum level.
Nilotinib Nilotinib The metabolism of Nilotinib can be increased when combined with Secobarbital.
Budesonide Budesonide Secobarbital may decrease the excretion rate of Budesonide which could result in a higher serum level.
Chloramphenicol Injection Chloramphenicol Injection The metabolism of Secobarbital can be decreased when combined with Chloramphenicol.
Desmopressin Desmopressin Desmopressin may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Betaine Betaine The therapeutic efficacy of Secobarbital can be decreased when used in combination with Glycine betaine.
OnabotulinumtoxinA Injection OnabotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Secobarbital is combined with Botulinum toxin type A.
RimabotulinumtoxinB Injection RimabotulinumtoxinB Injection The risk or severity of adverse effects can be increased when Secobarbital is combined with Botulinum Toxin Type B.
Doripenem Injection Doripenem Injection Secobarbital may decrease the excretion rate of Doripenem which could result in a higher serum level.
Arsenic Trioxide Injection Arsenic Trioxide Injection Secobarbital may increase the hypotensive activities of Arsenic trioxide.
Desvenlafaxine Desvenlafaxine The risk or severity of adverse effects can be increased when Secobarbital is combined with Desvenlafaxine.
Cevimeline Cevimeline Cevimeline may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Nebivolol Nebivolol The serum concentration of Nebivolol can be decreased when it is combined with Secobarbital.
Tretinoin Tretinoin The metabolism of Tretinoin can be increased when combined with Secobarbital.
Bendamustine Injection Bendamustine Injection The metabolism of Bendamustine can be increased when combined with Secobarbital.
Flecainide Flecainide The metabolism of Flecainide can be increased when combined with Secobarbital.
Certolizumab Injection Certolizumab Injection Secobarbital may decrease the excretion rate of Certolizumab pegol which could result in a higher serum level.
Ixabepilone Injection Ixabepilone Injection The metabolism of Ixabepilone can be increased when combined with Secobarbital.
Irinotecan Injection Irinotecan Injection The metabolism of Irinotecan can be increased when combined with Secobarbital.
Daptomycin Injection Daptomycin Injection Daptomycin may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Praziquantel Praziquantel The metabolism of Praziquantel can be increased when combined with Secobarbital.
Methylnaltrexone Injection Methylnaltrexone Injection Secobarbital may decrease the excretion rate of Methylnaltrexone which could result in a higher serum level.
Rufinamide Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Secobarbital.
Midazolam Midazolam The risk or severity of adverse effects can be increased when Secobarbital is combined with Midazolam.
Naltrexone Injection Naltrexone Injection The risk or severity of adverse effects can be increased when Secobarbital is combined with Naltrexone.
Dexrazoxane Injection Dexrazoxane Injection Dexrazoxane may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Eltrombopag Eltrombopag The metabolism of Eltrombopag can be increased when combined with Secobarbital.
Milnacipran Milnacipran The metabolism of Milnacipran can be increased when combined with Secobarbital.
Plerixafor Injection Plerixafor Injection Secobarbital may decrease the excretion rate of Plerixafor which could result in a higher serum level.
Sodium Phosphate Sodium Phosphate The therapeutic efficacy of Secobarbital can be decreased when used in combination with Sodium phosphate, monobasic.
Fesoterodine Fesoterodine Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Fesoterodine.
Betaxolol Betaxolol The serum concentration of Betaxolol can be decreased when it is combined with Secobarbital.
Iloperidone Iloperidone The risk or severity of adverse effects can be increased when Secobarbital is combined with Iloperidone.
Prasugrel Prasugrel Secobarbital may decrease the excretion rate of Prasugrel which could result in a higher serum level.
Lacosamide Lacosamide The risk or severity of adverse effects can be increased when Secobarbital is combined with Lacosamide.
Everolimus Everolimus The metabolism of Everolimus can be increased when combined with Secobarbital.
Tolvaptan (low blood sodium) Tolvaptan (low blood sodium) The metabolism of Secobarbital can be increased when combined with Tolvaptan.
Dronedarone Dronedarone The metabolism of Dronedarone can be increased when combined with Secobarbital.
AbobotulinumtoxinA Injection AbobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Secobarbital is combined with Botulinum toxin type A.
Pralatrexate Injection Pralatrexate Injection Secobarbital may decrease the excretion rate of Pralatrexate which could result in a higher serum level.
Palonosetron Injection Palonosetron Injection The risk or severity of adverse effects can be increased when Palonosetron is combined with Secobarbital.
Saxagliptin Saxagliptin Secobarbital may decrease the excretion rate of Saxagliptin which could result in a higher serum level.
Telavancin Injection Telavancin Injection Secobarbital may decrease the excretion rate of Telavancin which could result in a higher serum level.
Romidepsin Injection Romidepsin Injection The metabolism of Romidepsin can be increased when combined with Secobarbital.
Tapentadol Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Secobarbital.
Topotecan Topotecan Secobarbital may increase the excretion rate of Topotecan which could result in a lower serum level and potentially a reduction in efficacy.
Pazopanib Pazopanib The metabolism of Pazopanib can be increased when combined with Secobarbital.
Asenapine Asenapine The risk or severity of adverse effects can be increased when Secobarbital is combined with Asenapine.
Vigabatrin Vigabatrin The risk or severity of adverse effects can be increased when Secobarbital is combined with Vigabatrin.
Pitavastatin Pitavastatin The metabolism of Pitavastatin can be increased when combined with Secobarbital.
Albendazole Albendazole The metabolism of Albendazole can be increased when combined with Secobarbital.
Ulipristal Ulipristal The serum concentration of Ulipristal can be decreased when it is combined with Secobarbital.
Levonorgestrel Levonorgestrel The metabolism of Levonorgestrel can be increased when combined with Secobarbital.
Oxymorphone Oxymorphone The risk or severity of adverse effects can be increased when Secobarbital is combined with Oxymorphone.
Dalfampridine Dalfampridine Secobarbital may decrease the excretion rate of Dalfampridine which could result in a higher serum level.
IncobotulinumtoxinA Injection IncobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Secobarbital is combined with Botulinum toxin type A.
Cabazitaxel Injection Cabazitaxel Injection The metabolism of Cabazitaxel can be increased when combined with Secobarbital.
Ceftaroline Injection Ceftaroline Injection Ceftaroline fosamil may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Lurasidone Lurasidone The risk or severity of adverse effects can be increased when Secobarbital is combined with Lurasidone.
Acetaminophen Injection Acetaminophen Injection The metabolism of Secobarbital can be increased when combined with Acetaminophen.
Vilazodone Vilazodone The risk or severity of adverse effects can be increased when Secobarbital is combined with Vilazodone.
Ipilimumab Injection Ipilimumab Injection Secobarbital may decrease the excretion rate of Ipilimumab which could result in a higher serum level.
Denileukin Diftitox Injection Denileukin Diftitox Injection Secobarbital may increase the hypotensive activities of Aldesleukin.
Terbutaline Injection Terbutaline Injection The therapeutic efficacy of Secobarbital can be decreased when used in combination with Terbutaline.
Azilsartan Azilsartan Secobarbital may increase the hypotensive activities of Azilsartan medoxomil.
Busulfan Injection Busulfan Injection The metabolism of Busulfan can be increased when combined with Secobarbital.
Roflumilast Roflumilast The metabolism of Roflumilast can be increased when combined with Secobarbital.
Linagliptin Linagliptin The metabolism of Linagliptin can be increased when combined with Secobarbital.
Cyclophosphamide Injection Cyclophosphamide Injection The metabolism of Cyclophosphamide can be increased when combined with Secobarbital.
Rivaroxaban Rivaroxaban Secobarbital may decrease the excretion rate of Rivaroxaban which could result in a higher serum level.
Brentuximab Vedotin Injection Brentuximab Vedotin Injection The metabolism of Brentuximab vedotin can be increased when combined with Secobarbital.
Ruxolitinib Ruxolitinib The metabolism of Ruxolitinib can be increased when combined with Secobarbital.
Vandetanib Vandetanib The metabolism of Vandetanib can be increased when combined with Secobarbital.
Clobazam Clobazam The risk or severity of adverse effects can be increased when Clobazam is combined with Secobarbital.
Vemurafenib Vemurafenib The metabolism of Vemurafenib can be increased when combined with Secobarbital.
Deferiprone Deferiprone Secobarbital may decrease the excretion rate of Deferiprone which could result in a higher serum level.
Axitinib Axitinib The metabolism of Axitinib can be increased when combined with Secobarbital.
Crizotinib Crizotinib The metabolism of Crizotinib can be increased when combined with Secobarbital.
Cabergoline Cabergoline The metabolism of Secobarbital can be increased when combined with Cabergoline.
Naloxone Injection Naloxone Injection Secobarbital may decrease the excretion rate of Naloxone which could result in a higher serum level.
Fondaparinux Injection Fondaparinux Injection Secobarbital may decrease the excretion rate of Fondaparinux which could result in a higher serum level.
Ezogabine Ezogabine The risk or severity of adverse effects can be increased when Secobarbital is combined with Tiagabine.
Iloprost Iloprost Secobarbital may increase the hypotensive activities of Iloprost.
Enzalutamide Enzalutamide The metabolism of Enzalutamide can be increased when combined with Secobarbital.
Mirabegron Mirabegron Secobarbital may decrease the excretion rate of Mirabegron which could result in a higher serum level.
Regorafenib Regorafenib The metabolism of Regorafenib can be increased when combined with Secobarbital.
Bosutinib Bosutinib The metabolism of Bosutinib can be increased when combined with Secobarbital.
Linaclotide Linaclotide The therapeutic efficacy of Linaclotide can be decreased when used in combination with Secobarbital.
Cabozantinib (thyroid cancer) Cabozantinib (thyroid cancer) The metabolism of Cabozantinib can be increased when combined with Secobarbital.
Teduglutide Injection Teduglutide Injection Secobarbital may decrease the excretion rate of Teduglutide which could result in a higher serum level.
Alogliptin Alogliptin Secobarbital may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Ponatinib Ponatinib The metabolism of Ponatinib can be increased when combined with Secobarbital.
Pomalidomide Pomalidomide The metabolism of Pomalidomide can be increased when combined with Secobarbital.
Ado-trastuzumab Emtansine Injection Ado-trastuzumab Emtansine Injection The metabolism of Trastuzumab emtansine can be increased when combined with Secobarbital.
Apixaban Apixaban The metabolism of Apixaban can be increased when combined with Secobarbital.
Canagliflozin Canagliflozin The serum concentration of Canagliflozin can be decreased when it is combined with Secobarbital.
Methazolamide Methazolamide Secobarbital may increase the hypotensive activities of Methazolamide.
Dabrafenib Dabrafenib The metabolism of Dabrafenib can be increased when combined with Secobarbital.
Trametinib Trametinib Secobarbital may decrease the excretion rate of Trametinib which could result in a higher serum level.
Levomilnacipran Levomilnacipran The metabolism of Levomilnacipran can be increased when combined with Secobarbital.
Ertapenem Injection Ertapenem Injection Ertapenem may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Vortioxetine Vortioxetine The metabolism of Vortioxetine can be increased when combined with Secobarbital.
Perampanel Perampanel The metabolism of Perampanel can be increased when combined with Secobarbital.
Lomitapide Lomitapide The metabolism of Lomitapide can be increased when combined with Secobarbital.
Ketorolac Injection Ketorolac Injection The metabolism of Secobarbital can be increased when combined with Ketorolac.
Obinutuzumab Injection Obinutuzumab Injection Secobarbital may increase the hypotensive activities of Obinutuzumab.
Sofosbuvir Sofosbuvir Secobarbital may decrease the excretion rate of Sofosbuvir which could result in a higher serum level.
Dapagliflozin Dapagliflozin Secobarbital may increase the hypotensive activities of Dapagliflozin.
Apremilast Apremilast The metabolism of Apremilast can be increased when combined with Secobarbital.
Droxidopa Droxidopa Secobarbital may decrease the excretion rate of Droxidopa which could result in a higher serum level.
Ceritinib Ceritinib The metabolism of Ceritinib can be increased when combined with Secobarbital.
Eslicarbazepine Eslicarbazepine The risk or severity of adverse effects can be increased when Secobarbital is combined with Eslicarbazepine.
Idelalisib Idelalisib The metabolism of Idelalisib can be increased when combined with Secobarbital.
Testosterone Injection Testosterone Injection Secobarbital may decrease the excretion rate of Testosterone which could result in a higher serum level.
Empagliflozin Empagliflozin Secobarbital may increase the hypotensive activities of Empagliflozin.
Vorapaxar Vorapaxar The metabolism of Vorapaxar can be increased when combined with Secobarbital.
Hydrocodone Hydrocodone Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone.
Suvorexant Suvorexant Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Edoxaban Edoxaban Secobarbital may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Olaparib Olaparib The metabolism of Olaparib can be increased when combined with Secobarbital.
Methamphetamine Methamphetamine The risk or severity of adverse effects can be increased when Secobarbital is combined with Metamfetamine.
Tasimelteon Tasimelteon The risk or severity of adverse effects can be increased when Secobarbital is combined with Tasimelteon.
Riociguat Riociguat The metabolism of Riociguat can be increased when combined with Secobarbital.
Pirfenidone Pirfenidone The metabolism of Pirfenidone can be increased when combined with Secobarbital.
Nintedanib Nintedanib The metabolism of Nintedanib can be increased when combined with Secobarbital.
Risperidone Injection Risperidone Injection The risk or severity of adverse effects can be increased when Secobarbital is combined with Risperidone.
Palbociclib Palbociclib The metabolism of Palbociclib can be increased when combined with Secobarbital.
Panobinostat Panobinostat The metabolism of Panobinostat can be increased when combined with Secobarbital.
Dinutuximab Injection Dinutuximab Injection Secobarbital may increase the hypotensive activities of Dinutuximab.
Haloperidol Injection Haloperidol Injection The risk or severity of CNS depression can be increased when Secobarbital is combined with Haloperidol.
Amiloride Amiloride Secobarbital may increase the hypotensive activities of Amiloride.
Macitentan Macitentan Secobarbital may decrease the excretion rate of Macitentan which could result in a higher serum level.
Sonidegib Sonidegib The metabolism of Sonidegib can be increased when combined with Secobarbital.
Flibanserin Flibanserin The risk or severity of adverse effects can be increased when Secobarbital is combined with Flibanserin.
Brexpiprazole Brexpiprazole The risk or severity of adverse effects can be increased when Secobarbital is combined with Brexpiprazole.
Ziprasidone Injection Ziprasidone Injection The risk or severity of adverse effects can be increased when Ziprasidone is combined with Secobarbital.
Cariprazine Cariprazine The risk or severity of adverse effects can be increased when Secobarbital is combined with Cariprazine.
Penicillin G Procaine Injection Penicillin G Procaine Injection Secobarbital may decrease the excretion rate of Procaine benzylpenicillin which could result in a higher serum level.
Eluxadoline Eluxadoline The risk or severity of constipation can be increased when Secobarbital is combined with Eluxadoline.
Cobimetinib Cobimetinib The metabolism of Cobimetinib can be increased when combined with Secobarbital.
Trabectedin Injection Trabectedin Injection The metabolism of Trabectedin can be increased when combined with Secobarbital.
Osimertinib Osimertinib The metabolism of Osimertinib can be increased when combined with Secobarbital.
Alectinib Alectinib The metabolism of Alectinib can be increased when combined with Secobarbital.
Ixazomib Ixazomib The metabolism of Ixazomib can be increased when combined with Secobarbital.
Lesinurad Lesinurad Secobarbital may decrease the excretion rate of Lesinurad which could result in a higher serum level.
Amphotericin B Liposomal Injection Amphotericin B Liposomal Injection Secobarbital may increase the hypotensive activities of Amphotericin B.
Brivaracetam Injection Brivaracetam Injection The risk or severity of adverse effects can be increased when Secobarbital is combined with Brivaracetam.
Venetoclax Venetoclax The metabolism of Venetoclax can be increased when combined with Secobarbital.
Selexipag Selexipag The metabolism of Selexipag can be increased when combined with Secobarbital.
Pimavanserin Pimavanserin The risk or severity of adverse effects can be increased when Secobarbital is combined with Pimavanserin.
Diphenhydramine Injection Diphenhydramine Injection The risk or severity of adverse effects can be increased when Secobarbital is combined with Diphenhydramine.
Furosemide Injection Furosemide Injection Secobarbital may increase the hypotensive activities of Furosemide.
Rucaparib Rucaparib The metabolism of Rucaparib can be increased when combined with Secobarbital.
Lixisenatide Injection Lixisenatide Injection Secobarbital may decrease the excretion rate of Lixisenatide which could result in a higher serum level.
Ribociclib Ribociclib The metabolism of Ribociclib can be increased when combined with Secobarbital.
Brigatinib Brigatinib The metabolism of Brigatinib can be increased when combined with Secobarbital.
Doxepin (Insomnia) Doxepin (Insomnia) Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Doxepin.
Plecanatide Plecanatide The therapeutic efficacy of Plecanatide can be decreased when used in combination with Secobarbital.
Deutetrabenazine Deutetrabenazine The risk or severity of sedation and somnolence can be increased when Secobarbital is combined with Deutetrabenazine.
Valbenazine Valbenazine Secobarbital may decrease the excretion rate of Valbenazine which could result in a higher serum level.
Safinamide Safinamide The risk or severity of adverse effects can be increased when Secobarbital is combined with Safinamide.
Naldemedine Naldemedine Secobarbital may decrease the excretion rate of Naldemedine which could result in a higher serum level.
Midostaurin Midostaurin The metabolism of Midostaurin can be increased when combined with Secobarbital.
Neratinib Neratinib The metabolism of Neratinib can be increased when combined with Secobarbital.
Enasidenib Enasidenib The metabolism of Enasidenib can be increased when combined with Secobarbital.
Aprepitant/Fosaprepitant Injection Aprepitant/Fosaprepitant Injection The metabolism of Fosaprepitant can be increased when combined with Secobarbital.
Benznidazole Benznidazole Secobarbital may decrease the excretion rate of Benznidazole which could result in a higher serum level.
Copanlisib Injection Copanlisib Injection The metabolism of Copanlisib can be increased when combined with Secobarbital.
Delafloxacin Delafloxacin Secobarbital may decrease the excretion rate of Delafloxacin which could result in a higher serum level.
Abemaciclib Abemaciclib The metabolism of Abemaciclib can be increased when combined with Secobarbital.
Acalabrutinib Acalabrutinib The metabolism of Acalabrutinib can be increased when combined with Secobarbital.
Tetrabenazine Tetrabenazine The risk or severity of sedation and somnolence can be increased when Secobarbital is combined with Tetrabenazine.
Ertugliflozin Ertugliflozin Ertugliflozin may increase the excretion rate of Secobarbital which could result in a lower serum level and potentially a reduction in efficacy.
Buprenorphine Injection Buprenorphine Injection Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Apalutamide Apalutamide The metabolism of Apalutamide can be increased when combined with Secobarbital.
Baricitinib Baricitinib The metabolism of Baricitinib can be increased when combined with Secobarbital.
Lofexidine Lofexidine The therapeutic efficacy of Secobarbital can be increased when used in combination with Lofexidine.
Plazomicin Injection Plazomicin Injection Secobarbital may decrease the excretion rate of Plazomicin which could result in a higher serum level.
Binimetinib Binimetinib The metabolism of Binimetinib can be increased when combined with Secobarbital.
Ivosidenib Ivosidenib The metabolism of Ivosidenib can be increased when combined with Secobarbital.
Elagolix Elagolix The metabolism of Elagolix can be increased when combined with Secobarbital.
Cannabidiol Cannabidiol The risk or severity of adverse effects can be increased when Cannabidiol is combined with Secobarbital.
Dacomitinib Dacomitinib The metabolism of Dacomitinib can be increased when combined with Secobarbital.
Duvelisib Duvelisib The metabolism of Duvelisib can be increased when combined with Secobarbital.
Stiripentol Stiripentol The risk or severity of adverse effects can be increased when Secobarbital is combined with Stiripentol.
Gilteritinib Gilteritinib The metabolism of Gilteritinib can be increased when combined with Secobarbital.
Glasdegib Glasdegib The metabolism of Glasdegib can be increased when combined with Secobarbital.
Lorlatinib Lorlatinib The metabolism of Lorlatinib can be increased when combined with Secobarbital.
Paclitaxel (with albumin) Injection Paclitaxel (with albumin) Injection The metabolism of Paclitaxel can be increased when combined with Secobarbital.
Prucalopride Prucalopride The metabolism of Prucalopride can be increased when combined with Secobarbital.
Magnesium Citrate Magnesium Citrate The therapeutic efficacy of Magnesium citrate can be decreased when used in combination with Secobarbital.
Siponimod Siponimod The metabolism of Siponimod can be increased when combined with Secobarbital.
Acyclovir Ophthalmic Acyclovir Ophthalmic Acyclovir may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Erdafitinib Erdafitinib The metabolism of Erdafitinib can be increased when combined with Secobarbital.
Alpelisib Alpelisib The metabolism of Alpelisib can be increased when combined with Secobarbital.
Brexanolone Injection Brexanolone Injection The risk or severity of adverse effects can be increased when Secobarbital is combined with Brexanolone.
Solriamfetol Solriamfetol The risk or severity of adverse effects can be increased when Secobarbital is combined with Solriamfetol.
Triclabendazole Triclabendazole The metabolism of Triclabendazole can be increased when combined with Secobarbital.
Entrectinib Entrectinib The metabolism of Entrectinib can be increased when combined with Secobarbital.
Pexidartinib Pexidartinib The metabolism of Pexidartinib can be increased when combined with Secobarbital.
Istradefylline Istradefylline The metabolism of Istradefylline can be increased when combined with Secobarbital.
Pitolisant Pitolisant Secobarbital may decrease the excretion rate of Pitolisant which could result in a higher serum level.
Lefamulin Lefamulin The metabolism of Lefamulin can be increased when combined with Secobarbital.
Phenytoin Injection Phenytoin Injection The metabolism of Phenytoin can be increased when combined with Secobarbital.
Fosphenytoin Injection Fosphenytoin Injection The metabolism of Fosphenytoin can be increased when combined with Secobarbital.
Zanubrutinib Zanubrutinib The metabolism of Zanubrutinib can be increased when combined with Secobarbital.
Lumateperone Lumateperone The serum concentration of Lumateperone can be decreased when it is combined with Secobarbital.
Lasmiditan Lasmiditan The risk or severity of adverse effects can be increased when Secobarbital is combined with Lasmiditan.
Tazemetostat Tazemetostat The metabolism of Tazemetostat can be increased when combined with Secobarbital.
Ozanimod Ozanimod The metabolism of Ozanimod can be increased when combined with Secobarbital.
Selumetinib Selumetinib The metabolism of Selumetinib can be increased when combined with Secobarbital.
Rimegepant Rimegepant The metabolism of Rimegepant can be increased when combined with Secobarbital.
Tucatinib Tucatinib The metabolism of Tucatinib can be increased when combined with Secobarbital.
Selpercatinib Selpercatinib The serum concentration of Selpercatinib can be decreased when it is combined with Secobarbital.
Capmatinib Capmatinib The serum concentration of Capmatinib can be decreased when it is combined with Secobarbital.
Lemborexant Lemborexant The serum concentration of Lemborexant can be decreased when it is combined with Secobarbital.
Fenfluramine Fenfluramine The risk or severity of adverse effects can be increased when Secobarbital is combined with Fenfluramine.
Progestin-Only (drospirenone) Oral Contraceptives Progestin-Only (drospirenone) Oral Contraceptives The metabolism of Drospirenone can be increased when combined with Secobarbital.
Viloxazine Viloxazine The risk or severity of adverse effects can be increased when Secobarbital is combined with Viloxazine.
Tobramycin Injection Tobramycin Injection Tobramycin may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Theophylline Theophylline The metabolism of Theophylline can be increased when combined with Secobarbital.
Fenoprofen Fenoprofen Fenoprofen may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Indomethacin Indomethacin Indomethacin may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Mefenamic Acid Mefenamic Acid Mefenamic acid may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Naproxen Naproxen The metabolism of Naproxen can be increased when combined with Secobarbital.
Tolmetin Tolmetin Tolmetin may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Sulindac Sulindac Sulindac may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Trazodone Trazodone The risk or severity of adverse effects can be increased when Secobarbital is combined with Trazodone.
Isotretinoin Isotretinoin Secobarbital may decrease the excretion rate of Isotretinoin which could result in a higher serum level.
Sucralfate Sucralfate Sucralfate may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Floxuridine Floxuridine Floxuridine may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Phenobarbital Phenobarbital The metabolism of Phenobarbital can be increased when combined with Secobarbital.
Metaxalone Metaxalone The risk or severity of adverse effects can be increased when Secobarbital is combined with Metaxalone.
Methotrexate Injection Methotrexate Injection The metabolism of Secobarbital can be increased when combined with Methotrexate.
Levorphanol Levorphanol The risk or severity of adverse effects can be increased when Secobarbital is combined with Levorphanol.
Primidone Primidone The risk or severity of adverse effects can be increased when Primidone is combined with Secobarbital.
Methsuximide Methsuximide The risk or severity of adverse effects can be increased when Secobarbital is combined with Methsuximide.
Diethylpropion Diethylpropion The risk or severity of adverse effects can be increased when Secobarbital is combined with Diethylpropion.
Chlorpromazine Chlorpromazine The metabolism of Secobarbital can be increased when combined with Chlorpromazine.
Diazepam Diazepam The risk or severity of adverse effects can be increased when Secobarbital is combined with Diazepam.
Oxazepam Oxazepam The risk or severity of adverse effects can be increased when Secobarbital is combined with Oxazepam.
Flurazepam Flurazepam The risk or severity of adverse effects can be increased when Secobarbital is combined with Flurazepam.
Clorazepate Clorazepate The risk or severity of adverse effects can be increased when Secobarbital is combined with Clorazepic acid.
Lorazepam Lorazepam The risk or severity of adverse effects can be increased when Lorazepam is combined with Secobarbital.
Phenoxybenzamine Phenoxybenzamine Secobarbital may increase the hypotensive activities of Phenoxybenzamine.
Carmustine Carmustine The metabolism of Secobarbital can be increased when combined with Carmustine.
Amantadine Amantadine Secobarbital may decrease the excretion rate of Amantadine which could result in a higher serum level.
Codeine Codeine The risk or severity of adverse effects can be increased when Secobarbital is combined with Codeine.
Meprobamate Meprobamate The risk or severity of adverse effects can be increased when Meprobamate is combined with Secobarbital.
Chlordiazepoxide Chlordiazepoxide The risk or severity of adverse effects can be increased when Secobarbital is combined with Chlordiazepoxide.
Bromocriptine Bromocriptine The risk or severity of adverse effects can be increased when Secobarbital is combined with Bromocriptine.
Tranylcypromine Tranylcypromine Secobarbital may increase the hypotensive activities of Tranylcypromine.
Phenelzine Phenelzine Secobarbital may increase the hypotensive activities of Phenelzine.
Procarbazine Procarbazine The risk or severity of adverse effects can be increased when Secobarbital is combined with Procarbazine.
Ergoloid Mesylates Ergoloid Mesylates The risk or severity of adverse effects can be increased when Secobarbital is combined with Ergoloid mesylate.
Tetracycline Tetracycline Secobarbital may decrease the excretion rate of Tetracycline which could result in a higher serum level.
Minocycline Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Secobarbital.
Prochlorperazine Prochlorperazine The risk or severity of adverse effects can be increased when Secobarbital is combined with Prochlorperazine.
Thioridazine Thioridazine The risk or severity of adverse effects can be increased when Secobarbital is combined with Thioridazine.
Trifluoperazine Trifluoperazine The risk or severity of adverse effects can be increased when Secobarbital is combined with Trifluoperazine.
Bleomycin Bleomycin Bleomycin may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Dapsone Dapsone The metabolism of Dapsone can be increased when combined with Secobarbital.
Sulfadiazine Sulfadiazine The metabolism of Sulfadiazine can be increased when combined with Secobarbital.
Oxycodone Oxycodone The risk or severity of adverse effects can be increased when Secobarbital is combined with Oxycodone.
Methadone Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Secobarbital.
Oxybutynin Oxybutynin Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Oxybutynin.
Benztropine Benztropine Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Benzatropine.
Maprotiline Maprotiline Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Maprotiline.
Ibuprofen Ibuprofen The metabolism of Ibuprofen can be increased when combined with Secobarbital.
Trihexyphenidyl Trihexyphenidyl Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Trihexyphenidyl.
Orphenadrine Orphenadrine Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Perphenazine Perphenazine The metabolism of Perphenazine can be increased when combined with Secobarbital.
Azathioprine Azathioprine The metabolism of Azathioprine can be increased when combined with Secobarbital.
Fluphenazine Fluphenazine The risk or severity of adverse effects can be increased when Secobarbital is combined with Fluphenazine.
Phentermine Phentermine The metabolism of Phentermine can be increased when combined with Secobarbital.
Methylphenidate Methylphenidate The therapeutic efficacy of Methylphenidate can be decreased when used in combination with Secobarbital.
Amoxapine Amoxapine The metabolism of Amoxapine can be increased when combined with Secobarbital.
Sulfasalazine Sulfasalazine Sulfasalazine may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Doxorubicin Doxorubicin The metabolism of Doxorubicin can be increased when combined with Secobarbital.
Mechlorethamine Mechlorethamine The therapeutic efficacy of Secobarbital can be decreased when used in combination with Mechlorethamine.
Pyridostigmine Pyridostigmine The therapeutic efficacy of Secobarbital can be decreased when used in combination with Pyridostigmine.
Phenazopyridine Phenazopyridine Phenazopyridine may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Carbamazepine Carbamazepine Carbamazepine may increase the Change in thyroid function activities of Secobarbital.
Molindone Molindone The risk or severity of adverse effects can be increased when Secobarbital is combined with Molindone.
Methyldopa Methyldopa Secobarbital may increase the hypotensive activities of Methyldopa.
Clonidine Clonidine The risk or severity of sedation can be increased when Clonidine is combined with Secobarbital.
Prazosin Prazosin Secobarbital may increase the hypotensive activities of Prazosin.
Hydralazine Hydralazine Secobarbital may increase the hypotensive activities of Hydralazine.
Cimetidine Cimetidine Secobarbital may decrease the excretion rate of Cimetidine which could result in a higher serum level.
Gentamicin Injection Gentamicin Injection Gentamicin may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Warfarin Warfarin The metabolism of Warfarin can be increased when combined with Secobarbital.
Clonazepam Clonazepam The metabolism of Clonazepam can be increased when combined with Secobarbital.
Loperamide Loperamide The metabolism of Loperamide can be increased when combined with Secobarbital.
Promethazine Promethazine The risk or severity of adverse effects can be increased when Secobarbital is combined with Promethazine.
Meclofenamate Meclofenamate Meclofenamic acid may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Nitrofurantoin Nitrofurantoin Secobarbital may decrease the excretion rate of Nitrofurantoin which could result in a higher serum level.
Griseofulvin Griseofulvin The serum concentration of Griseofulvin can be decreased when it is combined with Secobarbital.
Digoxin Digoxin Secobarbital may decrease the excretion rate of Digoxin which could result in a higher serum level.
Loxapine Loxapine The risk or severity of adverse effects can be increased when Loxapine is combined with Secobarbital.
Chloroquine Chloroquine The metabolism of Chloroquine can be increased when combined with Secobarbital.
Quinine Quinine The metabolism of Quinine can be increased when combined with Secobarbital.
Ethosuximide Ethosuximide The risk or severity of adverse effects can be increased when Secobarbital is combined with Ethosuximide.
Triamterene Triamterene Secobarbital may increase the hypotensive activities of Triamterene.
Lactulose Lactulose The therapeutic efficacy of Lactulose can be decreased when used in combination with Secobarbital.
Chlorothiazide Chlorothiazide The risk or severity of hypotension and orthostatic hypotension can be increased when Secobarbital is combined with Chlorothiazide.
Chlorthalidone Chlorthalidone The risk or severity of hypotension and orthostatic hypotension can be increased when Secobarbital is combined with Chlorthalidone.
Metolazone Metolazone The risk or severity of hypotension and orthostatic hypotension can be increased when Secobarbital is combined with Metolazone.
Isosorbide Isosorbide The metabolism of Isosorbide can be increased when combined with Secobarbital.
Clindamycin Injection Clindamycin Injection The metabolism of Clindamycin can be increased when combined with Secobarbital.
Desipramine Desipramine Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Desipramine.
Amitriptyline Amitriptyline The metabolism of Amitriptyline can be increased when combined with Secobarbital.
Imipramine Imipramine The metabolism of Imipramine can be increased when combined with Secobarbital.
Probenecid Probenecid Secobarbital may decrease the excretion rate of Probenecid which could result in a higher serum level.
Quinidine Quinidine The metabolism of Quinidine can be increased when combined with Secobarbital.
Procainamide Procainamide Procainamide may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Isoniazid Isoniazid The therapeutic efficacy of Isoniazid can be decreased when used in combination with Secobarbital.
Pyrazinamide Pyrazinamide Pyrazinamide may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Disopyramide Disopyramide Disopyramide may increase the central nervous system depressant (CNS depressant) activities of Secobarbital.
Valproic Acid Valproic Acid The serum concentration of Secobarbital can be increased when it is combined with Valproic acid.
Tamoxifen Tamoxifen The metabolism of Tamoxifen can be increased when combined with Secobarbital.
Butabarbital Butabarbital The risk or severity of adverse effects can be increased when Butabarbital is combined with Secobarbital.
Liothyronine Liothyronine Liothyronine may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Methimazole Methimazole Secobarbital may decrease the excretion rate of Methimazole which could result in a higher serum level.
Chlorpropamide Chlorpropamide Secobarbital may decrease the excretion rate of Chlorpropamide which could result in a higher serum level.
Tolbutamide Tolbutamide The metabolism of Tolbutamide can be increased when combined with Secobarbital.
Tolazamide Tolazamide Secobarbital may decrease the excretion rate of Tolazamide which could result in a higher serum level.
Dextromethorphan Dextromethorphan The risk or severity of adverse effects can be increased when Secobarbital is combined with Dextromethorphan.
Cyclobenzaprine Cyclobenzaprine The risk or severity of CNS depression can be increased when Secobarbital is combined with Cyclobenzaprine.
Baclofen Baclofen The risk or severity of adverse effects can be increased when Baclofen is combined with Secobarbital.
Doxylamine Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Secobarbital.
Cyproheptadine Cyproheptadine Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Cyproheptadine.
Clemastine Clemastine The risk or severity of adverse effects can be increased when Clemastine is combined with Secobarbital.
Chlorpheniramine Chlorpheniramine The risk or severity of adverse effects can be increased when Secobarbital is combined with Chlorpheniramine.
Brompheniramine Brompheniramine The risk or severity of adverse effects can be increased when Dexbrompheniramine is combined with Secobarbital.
Meclizine Meclizine The risk or severity of adverse effects can be increased when Secobarbital is combined with Meclizine.
Ethambutol Ethambutol Ethambutol may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Methyclothiazide Methyclothiazide The risk or severity of hypotension and orthostatic hypotension can be increased when Secobarbital is combined with Methyclothiazide.
Hydrochlorothiazide Hydrochlorothiazide The risk or severity of hypotension and orthostatic hypotension can be increased when Secobarbital is combined with Hydrochlorothiazide.
Dantrolene Dantrolene The risk or severity of adverse effects can be increased when Secobarbital is combined with Dantrolene.
Chlorzoxazone Chlorzoxazone The risk or severity of adverse effects can be increased when Chlorzoxazone is combined with Secobarbital.
Carisoprodol Carisoprodol The risk or severity of adverse effects can be increased when Carisoprodol is combined with Secobarbital.
Methocarbamol Methocarbamol The risk or severity of adverse effects can be increased when Secobarbital is combined with Methocarbamol.
Pyridoxine Pyridoxine The metabolism of Secobarbital can be increased when combined with Pyridoxine.
Folic Acid Folic Acid Folic acid may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Disulfiram Disulfiram The therapeutic efficacy of Secobarbital can be decreased when used in combination with Disulfiram.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) The serum concentration of Propranolol can be decreased when it is combined with Secobarbital.
Minoxidil Minoxidil Secobarbital may increase the hypotensive activities of Minoxidil.
Nortriptyline Nortriptyline The metabolism of Nortriptyline can be increased when combined with Secobarbital.
Spironolactone Spironolactone Secobarbital may increase the hypotensive activities of Spironolactone.
Amphotericin B Injection Amphotericin B Injection Secobarbital may increase the hypotensive activities of Amphotericin B.
Mercaptopurine Mercaptopurine The serum concentration of Mercaptopurine can be decreased when it is combined with Secobarbital.
Phytonadione Phytonadione Secobarbital may decrease the excretion rate of Phylloquinone which could result in a higher serum level.
Amikacin Injection Amikacin Injection Amikacin may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Nadolol Nadolol The serum concentration of Nadolol can be decreased when it is combined with Secobarbital.
Butorphanol Injection Butorphanol Injection The risk or severity of adverse effects can be increased when Secobarbital is combined with Butorphanol.
Nalbuphine Injection Nalbuphine Injection The risk or severity of adverse effects can be increased when Secobarbital is combined with Nalbuphine.
Allopurinol Allopurinol Secobarbital may decrease the excretion rate of Allopurinol which could result in a higher serum level.
Trimethobenzamide Trimethobenzamide The risk or severity of adverse effects can be increased when Secobarbital is combined with Trimethobenzamide.
Flavoxate Flavoxate Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Flavoxate.
Papaverine Papaverine Secobarbital may increase the hypotensive activities of Papaverine.
Fluorouracil Injection Fluorouracil Injection The metabolism of Fluorouracil can be increased when combined with Secobarbital.
Colchicine Colchicine Secobarbital may decrease the excretion rate of Colchicine which could result in a higher serum level.
Cefaclor Cefaclor Cefaclor may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Cefadroxil Cefadroxil Cefadroxil may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Cefazolin Injection Cefazolin Injection Cefazolin may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Cephalexin Cephalexin Cephalexin may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Cefoxitin Injection Cefoxitin Injection Cefoxitin may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Dacarbazine Dacarbazine The metabolism of Dacarbazine can be increased when combined with Secobarbital.
Acetazolamide Acetazolamide The risk or severity of adverse effects can be increased when Secobarbital is combined with Acetazolamide.
Cefotaxime Injection Cefotaxime Injection Cefotaxime may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Calcitonin Salmon Injection Calcitonin Salmon Injection Salmon calcitonin may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Pyrantel Pyrantel The risk or severity of adverse effects can be increased when Secobarbital is combined with Pyrantel.
Thiotepa Injection Thiotepa Injection The metabolism of Secobarbital can be increased when combined with Thiotepa.
Vincristine Injection Vincristine Injection The metabolism of Vincristine can be increased when combined with Secobarbital.
Captopril Captopril Secobarbital may increase the hypotensive activities of Captopril.
Dipyridamole Dipyridamole Secobarbital may increase the hypotensive activities of Dipyridamole.
Isoxsuprine Isoxsuprine Secobarbital may increase the hypotensive activities of Isoxsuprine.
Vinblastine Vinblastine The metabolism of Vinblastine can be increased when combined with Secobarbital.
Ethacrynic Acid Ethacrynic Acid Secobarbital may increase the hypotensive activities of Etacrynic acid.
Colistimethate Injection Colistimethate Injection Colistimethate may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Metoprolol Metoprolol The serum concentration of Metoprolol can be decreased when it is combined with Secobarbital.
Hydroxyzine Hydroxyzine Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Secobarbital.
Thiothixene Thiothixene The risk or severity of adverse effects can be increased when Secobarbital is combined with Thiothixene.
Aspirin Aspirin Acetylsalicylic acid may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Salsalate Salsalate Salsalate may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Chlorambucil Chlorambucil The therapeutic efficacy of Secobarbital can be decreased when used in combination with Chlorambucil.
Alprazolam Alprazolam The risk or severity of adverse effects can be increased when Alprazolam is combined with Secobarbital.
Temazepam Temazepam The risk or severity of adverse effects can be increased when Temazepam is combined with Secobarbital.
Triazolam Triazolam The risk or severity of adverse effects can be increased when Secobarbital is combined with Triazolam.
Dicyclomine Dicyclomine Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Dicyclomine.
Hyoscyamine Hyoscyamine Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Hyoscyamine.
Propantheline Propantheline Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Propantheline.
Trimethoprim Trimethoprim Secobarbital may decrease the excretion rate of Trimethoprim which could result in a higher serum level.
Diltiazem Diltiazem The metabolism of Diltiazem can be increased when combined with Secobarbital.
Nifedipine Nifedipine The metabolism of Nifedipine can be increased when combined with Secobarbital.
Timolol Timolol The serum concentration of Timolol can be decreased when it is combined with Secobarbital.
Verapamil Verapamil The metabolism of Verapamil can be increased when combined with Secobarbital.
Atenolol Atenolol The serum concentration of Atenolol can be decreased when it is combined with Secobarbital.
Pindolol Pindolol The serum concentration of Pindolol can be decreased when it is combined with Secobarbital.
Cisplatin Injection Cisplatin Injection Cisplatin may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Diflunisal Diflunisal Diflunisal may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Piroxicam Piroxicam The metabolism of Piroxicam can be increased when combined with Secobarbital.
Bumetanide Bumetanide Secobarbital may increase the hypotensive activities of Bumetanide.
Etoposide Etoposide The metabolism of Etoposide can be increased when combined with Secobarbital.
Glipizide Glipizide Secobarbital may decrease the excretion rate of Glipizide which could result in a higher serum level.
Indapamide Indapamide The risk or severity of hypotension and orthostatic hypotension can be increased when Secobarbital is combined with Indapamide.
Amoxicillin Amoxicillin Secobarbital may decrease the excretion rate of Amoxicillin which could result in a higher serum level.
Oxacillin Injection Oxacillin Injection Secobarbital may decrease the excretion rate of Oxacillin which could result in a higher serum level.
Pentoxifylline Pentoxifylline The serum concentration of Pentoxifylline can be decreased when it is combined with Secobarbital.
Pentamidine Injection Pentamidine Injection Pentamidine may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Ceftriaxone Injection Ceftriaxone Injection Ceftriaxone may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Labetalol Labetalol The serum concentration of Labetalol can be decreased when it is combined with Secobarbital.
Auranofin Auranofin Secobarbital may decrease the excretion rate of Auranofin which could result in a higher serum level.
Leuprolide Injection Leuprolide Injection Leuprolide may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Gemfibrozil Gemfibrozil Secobarbital may decrease the excretion rate of Gemfibrozil which could result in a higher serum level.
Guanabenz Guanabenz The metabolism of Guanabenz can be increased when combined with Secobarbital.
Dipivefrin Ophthalmic Dipivefrin Ophthalmic Adefovir dipivoxil may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Ceftazidime Injection Ceftazidime Injection Ceftazidime may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Ketoprofen Ketoprofen Ketoprofen may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Cefotetan Injection Cefotetan Injection Cefotetan may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Pimozide Pimozide The metabolism of Pimozide can be increased when combined with Secobarbital.
Enalapril Enalapril Secobarbital may increase the hypotensive activities of Enalapril.
Flurbiprofen Flurbiprofen Flurbiprofen may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Amiodarone Amiodarone The metabolism of Amiodarone can be increased when combined with Secobarbital.
Aztreonam Injection Aztreonam Injection Aztreonam may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Buspirone Buspirone Secobarbital may decrease the excretion rate of Buspirone which could result in a higher serum level.
Lovastatin Lovastatin The metabolism of Lovastatin can be increased when combined with Secobarbital.
Ciprofloxacin Ciprofloxacin Secobarbital may decrease the excretion rate of Ciprofloxacin which could result in a higher serum level.
Mesalamine Mesalamine Mesalazine may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Diclofenac Diclofenac The metabolism of Diclofenac can be increased when combined with Secobarbital.
Fluoxetine Fluoxetine Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Nimodipine Nimodipine The metabolism of Nimodipine can be increased when combined with Secobarbital.
Clozapine Clozapine Clozapine may increase the central nervous system depressant (CNS depressant) activities of Secobarbital.
Estazolam Estazolam The risk or severity of adverse effects can be increased when Secobarbital is combined with Estazolam.
Didanosine Didanosine Secobarbital may decrease the excretion rate of Didanosine which could result in a higher serum level.
Pentostatin Injection Pentostatin Injection Secobarbital may decrease the excretion rate of Pentostatin which could result in a higher serum level.
Benazepril Benazepril Secobarbital may increase the hypotensive activities of Benazepril.
Etodolac Etodolac Etodolac may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Felodipine Felodipine Secobarbital may increase the hypotensive activities of Felodipine.
Fosinopril Fosinopril Secobarbital may increase the hypotensive activities of Fosinopril.
Nabumetone Nabumetone Nabumetone may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Quinapril Quinapril Secobarbital may increase the hypotensive activities of Quinapril.
Ramipril Ramipril Ramipril may increase the hypotensive activities of Secobarbital.
Simvastatin Simvastatin The metabolism of Simvastatin can be increased when combined with Secobarbital.
Amlodipine Amlodipine The metabolism of Amlodipine can be increased when combined with Secobarbital.
Teniposide Injection Teniposide Injection The serum concentration of Teniposide can be decreased when it is combined with Secobarbital.
Lisinopril Lisinopril Secobarbital may increase the hypotensive activities of Lisinopril.
Oxaprozin Oxaprozin Oxaprozin may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Sotalol Sotalol The serum concentration of Sotalol can be decreased when it is combined with Secobarbital.
Bisoprolol Bisoprolol The serum concentration of Bisoprolol can be decreased when it is combined with Secobarbital.
Zolpidem Zolpidem Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Doxazosin Doxazosin Secobarbital may increase the hypotensive activities of Doxazosin.
Terazosin Terazosin Secobarbital may increase the hypotensive activities of Terazosin.
Isradipine Isradipine The metabolism of Isradipine can be increased when combined with Secobarbital.
Omeprazole Omeprazole The metabolism of Omeprazole can be increased when combined with Secobarbital.
Cisapride Cisapride The metabolism of Cisapride can be increased when combined with Secobarbital.
Gabapentin Gabapentin The risk or severity of adverse effects can be increased when Secobarbital is combined with Gabapentin.
Fluvastatin Fluvastatin The metabolism of Fluvastatin can be increased when combined with Secobarbital.
Venlafaxine Venlafaxine The risk or severity of adverse effects can be increased when Venlafaxine is combined with Secobarbital.
Nizatidine Nizatidine The therapeutic efficacy of Secobarbital can be decreased when used in combination with Nizatidine.
Famciclovir Famciclovir The metabolism of Famciclovir can be increased when combined with Secobarbital.
Fluvoxamine Fluvoxamine The risk or severity of adverse effects can be increased when Secobarbital is combined with Fluvoxamine.
Nefazodone Nefazodone The risk or severity of adverse effects can be increased when Secobarbital is combined with Nefazodone.
Lamotrigine Lamotrigine The serum concentration of Lamotrigine can be decreased when it is combined with Secobarbital.
Losartan Losartan Secobarbital may increase the hypotensive activities of Losartan.
Valacyclovir Valacyclovir Valaciclovir may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Tramadol Tramadol The metabolism of Tramadol can be increased when combined with Secobarbital.
Vinorelbine Injection Vinorelbine Injection The metabolism of Vinorelbine can be increased when combined with Secobarbital.
Carboplatin Injection Carboplatin Injection Carboplatin may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Moexipril Moexipril Secobarbital may increase the hypotensive activities of Moexipril.
Lansoprazole Lansoprazole The metabolism of Lansoprazole can be increased when combined with Secobarbital.
Ifosfamide Injection Ifosfamide Injection The metabolism of Ifosfamide can be increased when combined with Secobarbital.
Nicardipine Nicardipine The metabolism of Nicardipine can be increased when combined with Secobarbital.
Bupropion Bupropion The risk or severity of adverse effects can be increased when Secobarbital is combined with Bupropion.
Ticlopidine Ticlopidine The metabolism of Secobarbital can be increased when combined with Ticlopidine.
Metformin Metformin Metformin may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Nisoldipine Nisoldipine Secobarbital may increase the hypotensive activities of Nisoldipine.
Lamivudine Lamivudine Secobarbital may decrease the excretion rate of Lamivudine which could result in a higher serum level.
Riluzole Riluzole The risk or severity of adverse effects can be increased when Secobarbital is combined with Riluzole.
Amifostine Injection Amifostine Injection Secobarbital may increase the hypotensive activities of Amifostine.
Acarbose Acarbose Acarbose may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Anastrozole Anastrozole The metabolism of Anastrozole can be increased when combined with Secobarbital.
Gemcitabine Injection Gemcitabine Injection Secobarbital may decrease the excretion rate of Gemcitabine which could result in a higher serum level.
Docetaxel Injection Docetaxel Injection The metabolism of Docetaxel can be increased when combined with Secobarbital.
Cidofovir Injection Cidofovir Injection Cidofovir may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Meropenem Injection Meropenem Injection Secobarbital may decrease the excretion rate of Meropenem which could result in a higher serum level.
Clomipramine Clomipramine The metabolism of Clomipramine can be increased when combined with Secobarbital.
Zafirlukast Zafirlukast The metabolism of Zafirlukast can be increased when combined with Secobarbital.
Fosfomycin Fosfomycin Secobarbital may decrease the excretion rate of Fosfomycin which could result in a higher serum level.
Mirtazapine Mirtazapine Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Trandolapril Trandolapril Secobarbital may increase the hypotensive activities of Trandolapril.
Topiramate Topiramate The risk or severity of adverse effects can be increased when Topiramate is combined with Secobarbital.
Zileuton Zileuton The metabolism of Zileuton can be increased when combined with Secobarbital.
Valsartan Valsartan Secobarbital may increase the hypotensive activities of Valsartan.
Pramipexole Pramipexole Secobarbital may increase the sedative activities of Pramipexole.
Donepezil Donepezil The therapeutic efficacy of Secobarbital can be decreased when used in combination with Donepezil.
Azithromycin Azithromycin The metabolism of Azithromycin can be increased when combined with Secobarbital.
Loratadine Loratadine Secobarbital may increase the anticholinergic activities of Loratadine.
Carvedilol Carvedilol The serum concentration of Carvedilol can be decreased when it is combined with Secobarbital.
Nilutamide Nilutamide Secobarbital may decrease the excretion rate of Nilutamide which could result in a higher serum level.
Flutamide Flutamide The metabolism of Flutamide can be increased when combined with Secobarbital.
Selegiline Selegiline The metabolism of Selegiline can be increased when combined with Secobarbital.
Bicalutamide Bicalutamide The metabolism of Bicalutamide can be increased when combined with Secobarbital.
Sertraline Sertraline The risk or severity of adverse effects can be increased when Secobarbital is combined with Sertraline.
Propafenone Propafenone The serum concentration of Propafenone can be decreased when it is combined with Secobarbital.
Irbesartan Irbesartan The metabolism of Irbesartan can be increased when combined with Secobarbital.
Tamsulosin Tamsulosin Secobarbital may increase the hypotensive activities of Tamsulosin.
Ropinirole Ropinirole The metabolism of Ropinirole can be increased when combined with Secobarbital.
Quetiapine Quetiapine Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Quetiapine.
Cefepime Injection Cefepime Injection Cefepime may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Cefprozil Cefprozil Cefprozil may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Cefpodoxime Cefpodoxime Cefpodoxime may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Cetirizine Cetirizine The risk or severity of adverse effects can be increased when Cetirizine is combined with Secobarbital.
Paroxetine Paroxetine The risk or severity of adverse effects can be increased when Secobarbital is combined with Paroxetine.
Tolcapone Tolcapone The risk or severity of adverse effects can be increased when Tolcapone is combined with Secobarbital.
Citalopram Citalopram The risk or severity of adverse effects can be increased when Secobarbital is combined with Citalopram.
Capecitabine Capecitabine The metabolism of Capecitabine can be increased when combined with Secobarbital.
Efavirenz Efavirenz The risk or severity of adverse effects can be increased when Secobarbital is combined with Efavirenz.
Abacavir Abacavir Secobarbital may decrease the excretion rate of Abacavir which could result in a higher serum level.
Pioglitazone Pioglitazone The metabolism of Pioglitazone can be increased when combined with Secobarbital.
Celecoxib Celecoxib The metabolism of Celecoxib can be increased when combined with Secobarbital.
Rosiglitazone Rosiglitazone The metabolism of Rosiglitazone can be increased when combined with Secobarbital.
Tolterodine Tolterodine Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Tolterodine.
Thalidomide Thalidomide Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Oseltamivir Oseltamivir Oseltamivir may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Balsalazide Balsalazide Balsalazide may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Nateglinide Nateglinide Secobarbital may decrease the excretion rate of Nateglinide which could result in a higher serum level.
Galantamine Galantamine The therapeutic efficacy of Secobarbital can be decreased when used in combination with Galantamine.
Levetiracetam Levetiracetam The risk or severity of adverse effects can be increased when Secobarbital is combined with Levetiracetam.
Rabeprazole Rabeprazole Secobarbital may decrease the excretion rate of Rabeprazole which could result in a higher serum level.
Terbinafine Terbinafine The metabolism of Terbinafine can be increased when combined with Secobarbital.

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