Secobarbital

Secobarbital is used on a short-term basis to treat insomnia (difficulty falling asleep or staying asleep). It is also used to relieve anxiety before surgery. Secobarbital is in a class of medications called barbiturates. It works by slowing activity in the brain.

Secobarbital comes as a capsule to take by mouth. When secobarbital is used to treat insomnia, it is usually taken at bedtime as needed for sleep. When secobarbital is used to relieve anxiety before surgery, it is usually taken 1 to 2 hours before surgery. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take secobarbital exactly as directed.

Your sleep problems should improve within 7 to 10 days after you start taking secobarbital. Call your doctor if your sleep problems do not improve during this time, if they get worse at any time during your treatment, or if you notice any changes in your thoughts or behavior.

Secobarbital should normally be taken for short periods of time. If you take secobarbital for 2 weeks or longer, secobarbital may not help you sleep as well as it did when you first began to take the medication. If you take secobarbital for a long time, you may also develop dependence ('addiction,' a need to continue taking the medication) on secobarbital. Talk to your doctor about the risks of taking secobarbital for 2 weeks or longer. Do not take a larger dose of secobarbital, take it more often, or take it for a longer time than prescribed by your doctor.

Do not stop taking secobarbital without talking to your doctor. Your doctor will probably decrease your dose gradually. If you suddenly stop taking secobarbital, you may develop anxiety, muscle twitching, uncontrollable shaking of your hands or fingers, weakness, dizziness, changes in vision, nausea, vomiting, or difficulty falling asleep or staying asleep, or you may experience more severe withdrawal symptoms such as seizures or extreme confusion.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking secobarbital,

• tell your doctor and pharmacist if you are allergic to secobarbital; other barbiturates such as amobarbital (Amytal, in Tuinal), butabarbital (Butisol), pentobarbital, or phenobarbital; any other medications, or any of the ingredients in secobarbital capsules. Ask your pharmacist for a list of the ingredients.

• tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: anticoagulants ('blood thinners') such as warfarin (Coumadin); antihistamines; doxycycline (Doryx, Vibramycin; Vibra-tabs); griseofulvin (Fulvicin-U/F, Grifulvin V, Gris-PEG ); hormone replacement therapy; monoamine oxidase (MAO) inhibitors such as isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate); medications for depression,pain, colds, or allergies; certain medictations for seizures such as phenytoin (Dilantin) and valproic acid (Depakene); muscle relaxants; oral steroids such as dexamethasone (Decadron, Dexone), methylprednisolone (Medrol), and prednisone (Deltasone); sedatives; sleeping pills; and tranquilizers. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

• tell your doctor if you have or have ever had porphyria (condition in which certain natural substances build up in the body and may cause stomach pain, changes in thinking and behavior, and other symptoms); any condition that causes shortness of breath or difficulty breathing; or liver disease. Your doctor will probably tell you not to take secobarbital.

• tell your doctor if you drink or have ever drunk large amounts of alcohol, use or have ever used street drugs, or have overused prescription medications.Also tell your doctor if you have ever thought about killing yourself or tried to do so and if you have or have ever had depression; pain; or kidney disease.

• tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking secobarbital, call your doctor.

• you should know that secobarbital may decrease the effectiveness of hormonal contraceptives (birth control pills, patches, rings, injections, implants, or intrauterine devices). Talk to your doctor about methods of birth control that will work for you while you are taking secobarbital. Tell your doctor if you have a missed period or think you may be pregnant while you are taking secobarbital.

• talk to your doctor about the risks and benefits of taking this medication if you are 65 years of age or older. Older adults should not usually take secobarbital to treat conditions other than seizures because it is not as safe as other medications that can be used to treat the same conditions.

• if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking secobarbital.

• you should know that this medication may make you drowsy during the daytime. Do not drive a car or operate machinery until you know how this medication affects you.

• do not drink alcohol during your treatment with secobarbital. Alcohol can make the side effects of secobarbital worse.

• you should know that some people who took medications for sleep got out of bed and drove their cars, prepared and ate food, had sex, made phone calls, or were involved in other activities while partially asleep. After they woke up, these people were usually unable to remember what they had done. Call your doctor right away if you find out that you have been driving or doing anything else while you were sleeping.

Unless your doctor tells you otherwise, continue your normal diet.

Secobarbital is usually taken at bedtime. If you forget to take secobarbital at bedtime, you are unable to fall asleep, and you will still be able to stay in bed for a full night's sleep, you may take secobarbital at that time. Do not take a double dose of secobarbital to make up for a missed dose.

• Secobarbital may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • drowsiness

  • difficulty falling asleep or staying asleep

  • nightmares

  • headache

  • dizziness

  • nervousness

  • agitation

  • excitement

  • restlessness

  • confusion

  • nausea

  • vomiting

  • diarrhea

  • constipation

• Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:

  • hallucinating (seeing things or hearing voices that do not exist)

  • slow, shallow breathing

  • slow heartbeat

  • hives

  • rash

  • itching

  • swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs

  • difficulty breathing or swallowing

  • hoarseness

• Secobarbital may cause other side effects. Tell your doctor if you have any unusual problems during your treatment with secobarbital.

• If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Store secobarbital in a safe place so that no one else can take it accidentally or on purpose. Keep track of how many capsules are left so you will know if any are missing.

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Symptoms of overdose may include:

• slowed breathing

• low body temperature

Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your response to secobarbital.

This prescription is not refillable.

Do not let anyone else take your medication.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

• quinalbarbitone sodium

Drug	Interaction
Repaglinide	Repaglinide The metabolism of Repaglinide can be increased when combined with Secobarbital.
Montelukast	Montelukast The metabolism of Montelukast can be increased when combined with Secobarbital.
Leflunomide	Leflunomide The metabolism of Leflunomide can be increased when combined with Secobarbital.
Atorvastatin	Atorvastatin The metabolism of Atorvastatin can be increased when combined with Secobarbital.
Dolasetron	Dolasetron The risk or severity of adverse effects can be increased when Secobarbital is combined with Dolasetron.
Aminophylline	Aminophylline The therapeutic efficacy of Secobarbital can be decreased when used in combination with Aminophylline.
Anagrelide	Anagrelide The metabolism of Anagrelide can be increased when combined with Secobarbital.
Bisacodyl	Bisacodyl The therapeutic efficacy of Bisacodyl can be decreased when used in combination with Secobarbital.
Cilostazol	Cilostazol The metabolism of Cilostazol can be increased when combined with Secobarbital.
Clopidogrel	Clopidogrel The metabolism of Clopidogrel can be increased when combined with Secobarbital.
Diphenoxylate	Diphenoxylate The risk or severity of adverse effects can be increased when Secobarbital is combined with Diphenoxylate.
Estrogen and Progestin (Oral Contraceptives)	Estrogen and Progestin (Oral Contraceptives) The metabolism of Secobarbital can be increased when combined with Conjugated estrogens.
Fenofibrate	Fenofibrate The metabolism of Fenofibrate can be increased when combined with Secobarbital.
Guanfacine	Guanfacine The risk or severity of adverse effects can be increased when Secobarbital is combined with Guanfacine.
Magnesium Hydroxide	Magnesium Hydroxide Secobarbital may decrease the excretion rate of Magnesium hydroxide which could result in a higher serum level.
Magnesium Oxide	Magnesium Oxide The therapeutic efficacy of Magnesium oxide can be decreased when used in combination with Secobarbital.
Mycophenolate	Mycophenolate Secobarbital may decrease the excretion rate of Mycophenolic acid which could result in a higher serum level.
Naratriptan	Naratriptan The risk or severity of adverse effects can be increased when Secobarbital is combined with Naratriptan.
Olsalazine	Olsalazine Olsalazine may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Paregoric	Paregoric The risk or severity of adverse effects can be increased when Secobarbital is combined with Morphine.
Penbutolol	Penbutolol The serum concentration of Acebutolol can be decreased when it is combined with Secobarbital.
Pentazocine	Pentazocine The risk or severity of adverse effects can be increased when Secobarbital is combined with Pentazocine.
Polyethylene glycol-electrolyte solution (PEG-ES)	Polyethylene glycol-electrolyte solution (PEG-ES) The therapeutic efficacy of Polyethylene glycol can be decreased when used in combination with Secobarbital.
Potassium	Potassium Potassium may increase the excretion rate of Secobarbital which could result in a lower serum level and potentially a reduction in efficacy.
Prednisone	Prednisone Secobarbital may decrease the excretion rate of Prednisone which could result in a higher serum level.
Psyllium	Psyllium The therapeutic efficacy of Plantago seed can be decreased when used in combination with Secobarbital.
Ranitidine	Ranitidine The metabolism of Ranitidine can be increased when combined with Secobarbital.
Reserpine	Reserpine Secobarbital may increase the hypotensive activities of Reserpine.
Rizatriptan	Rizatriptan The risk or severity of adverse effects can be increased when Secobarbital is combined with Rizatriptan.
Sumatriptan	Sumatriptan The risk or severity of adverse effects can be increased when Secobarbital is combined with Sumatriptan.
Tacrolimus	Tacrolimus The metabolism of Tacrolimus can be increased when combined with Secobarbital.
Tizanidine	Tizanidine The metabolism of Tizanidine can be increased when combined with Secobarbital.
Zolmitriptan	Zolmitriptan The metabolism of Zolmitriptan can be increased when combined with Secobarbital.
Ampicillin Injection	Ampicillin Injection Ampicillin may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Doxycycline Injection	Doxycycline Injection The serum concentration of Doxycycline can be decreased when it is combined with Secobarbital.
Fluconazole Injection	Fluconazole Injection Fluconazole may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Foscarnet Injection	Foscarnet Injection Foscarnet may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Hydromorphone Injection	Hydromorphone Injection The risk or severity of adverse effects can be increased when Hydromorphone is combined with Secobarbital.
Levofloxacin Injection	Levofloxacin Injection Secobarbital may decrease the excretion rate of Levofloxacin which could result in a higher serum level.
Meperidine Injection	Meperidine Injection Secobarbital may increase the hypotensive and central nervous system depressant (CNS depressant) activities of Meperidine.
Metoclopramide Injection	Metoclopramide Injection The risk or severity of sedation can be increased when Metoclopramide is combined with Secobarbital.
Metronidazole Injection	Metronidazole Injection The therapeutic efficacy of Secobarbital can be decreased when used in combination with Metronidazole.
Morphine Injection	Morphine Injection The risk or severity of adverse effects can be increased when Secobarbital is combined with Morphine.
Pamidronate Injection	Pamidronate Injection Pamidronic acid may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Vancomycin Injection	Vancomycin Injection Secobarbital may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Zidovudine Injection	Zidovudine Injection The metabolism of Zidovudine can be increased when combined with Secobarbital.
Altretamine	Altretamine The therapeutic efficacy of Secobarbital can be decreased when used in combination with Amphetamine.
Cefuroxime	Cefuroxime Cefuroxime may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Cyclosporine	Cyclosporine The metabolism of Cyclosporine can be increased when combined with Secobarbital.
Ondansetron	Ondansetron The risk or severity of adverse effects can be increased when Secobarbital is combined with Ondansetron.
Granisetron	Granisetron The risk or severity of adverse effects can be increased when Secobarbital is combined with Granisetron.
Torsemide	Torsemide The metabolism of Torasemide can be increased when combined with Secobarbital.
Olanzapine	Olanzapine The risk or severity of adverse effects can be increased when Olanzapine is combined with Secobarbital.
Alosetron	Alosetron The metabolism of Alosetron can be increased when combined with Secobarbital.
Dofetilide	Dofetilide The metabolism of Dofetilide can be increased when combined with Secobarbital.
Entacapone	Entacapone The risk or severity of adverse effects can be increased when Secobarbital is combined with Entacapone.
Eprosartan	Eprosartan Secobarbital may increase the hypotensive activities of Eprosartan.
Hydroxychloroquine	Hydroxychloroquine The therapeutic efficacy of Hydroxychloroquine can be decreased when used in combination with Secobarbital.
Meloxicam	Meloxicam Meloxicam may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Orlistat	Orlistat Orlistat can cause a decrease in the absorption of Secobarbital resulting in a reduced serum concentration and potentially a decrease in efficacy.
Oxcarbazepine	Oxcarbazepine The risk or severity of adverse effects can be increased when Secobarbital is combined with Oxcarbazepine.
Pantoprazole	Pantoprazole Pantoprazole may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Telmisartan	Telmisartan Secobarbital may increase the hypotensive activities of Telmisartan.
Temozolomide	Temozolomide Secobarbital may decrease the excretion rate of Temozolomide which could result in a higher serum level.
Zaleplon	Zaleplon The risk or severity of adverse effects can be increased when Secobarbital is combined with Zaleplon.
Desloratadine	Desloratadine The risk or severity of adverse effects can be increased when Secobarbital is combined with Desloratadine.
Linezolid	Linezolid The risk or severity of adverse effects can be increased when Secobarbital is combined with Linezolid.
Rivastigmine	Rivastigmine The therapeutic efficacy of Secobarbital can be decreased when used in combination with Rivastigmine.
Trimipramine	Trimipramine The metabolism of Trimipramine can be increased when combined with Secobarbital.
Glycopyrrolate	Glycopyrrolate Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Glycopyrronium.
Perindopril	Perindopril Perindopril may increase the hypotensive activities of Secobarbital.
Tenofovir	Tenofovir Tenofovir may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Choline Magnesium Trisalicylate	Choline Magnesium Trisalicylate Choline magnesium trisalicylate may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Sirolimus	Sirolimus The metabolism of Sirolimus can be increased when combined with Secobarbital.
Eplerenone	Eplerenone Secobarbital may increase the hypotensive activities of Eplerenone.
Escitalopram	Escitalopram The risk or severity of adverse effects can be increased when Secobarbital is combined with Escitalopram.
Olmesartan	Olmesartan Secobarbital may increase the hypotensive activities of Olmesartan.
Zonisamide	Zonisamide The risk or severity of adverse effects can be increased when Secobarbital is combined with Zonisamide.
Aripiprazole	Aripiprazole The metabolism of Aripiprazole can be increased when combined with Secobarbital.
Atomoxetine	Atomoxetine The risk or severity of adverse effects can be increased when Atomoxetine is combined with Secobarbital.
Dexmethylphenidate	Dexmethylphenidate The risk or severity of adverse effects can be increased when Secobarbital is combined with Dexmethylphenidate.
Atazanavir	Atazanavir Atazanavir may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Almotriptan	Almotriptan The metabolism of Almotriptan can be increased when combined with Secobarbital.
Eletriptan	Eletriptan The risk or severity of adverse effects can be increased when Eletriptan is combined with Secobarbital.
Mefloquine	Mefloquine The therapeutic efficacy of Secobarbital can be decreased when used in combination with Mefloquine.
Polyethylene Glycol 3350	Polyethylene Glycol 3350 The therapeutic efficacy of Polyethylene glycol can be decreased when used in combination with Secobarbital.
Rosuvastatin	Rosuvastatin The metabolism of Rosuvastatin can be increased when combined with Secobarbital.
Emtricitabine	Emtricitabine Secobarbital may decrease the excretion rate of Emtricitabine which could result in a higher serum level.
Memantine	Memantine The therapeutic efficacy of Secobarbital can be decreased when used in combination with Memantine.
Tegaserod	Tegaserod The therapeutic efficacy of Tegaserod can be decreased when used in combination with Secobarbital.
Tadalafil	Tadalafil Secobarbital may decrease the excretion rate of Tadalafil which could result in a higher serum level.
Frovatriptan	Frovatriptan The metabolism of Frovatriptan can be increased when combined with Secobarbital.
Progesterone	Progesterone The metabolism of Progesterone can be increased when combined with Secobarbital.
Apomorphine Injection	Apomorphine Injection The metabolism of Apomorphine can be increased when combined with Secobarbital.
Protriptyline	Protriptyline The metabolism of Protriptyline can be increased when combined with Secobarbital.
Duloxetine	Duloxetine The risk or severity of adverse effects can be increased when Secobarbital is combined with Duloxetine.
Norethindrone	Norethindrone The metabolism of Norethisterone can be increased when combined with Secobarbital.
Tinidazole	Tinidazole Secobarbital may decrease the excretion rate of Tinidazole which could result in a higher serum level.
Trospium	Trospium Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Trospium.
Cefditoren	Cefditoren Secobarbital may decrease the excretion rate of Cefdinir which could result in a higher serum level.
Cinacalcet	Cinacalcet The metabolism of Cinacalcet can be increased when combined with Secobarbital.
Cyanocobalamin Injection	Cyanocobalamin Injection Hydroxocobalamin may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Erlotinib	Erlotinib The serum concentration of Erlotinib can be decreased when it is combined with Secobarbital.
Eszopiclone	Eszopiclone The risk or severity of CNS depression can be increased when Secobarbital is combined with Eszopiclone.
Ganciclovir	Ganciclovir The therapeutic efficacy of Ganciclovir can be decreased when used in combination with Secobarbital.
Ribavirin	Ribavirin Secobarbital may decrease the excretion rate of Ribavirin which could result in a higher serum level.
Solifenacin	Solifenacin Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Valganciclovir	Valganciclovir The therapeutic efficacy of Valganciclovir can be decreased when used in combination with Secobarbital.
Voriconazole	Voriconazole The serum concentration of Voriconazole can be decreased when it is combined with Secobarbital.
Adefovir	Adefovir Adefovir may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Dextroamphetamine	Dextroamphetamine The therapeutic efficacy of Secobarbital can be decreased when used in combination with Amphetamine.
Entecavir	Entecavir The metabolism of Entecavir can be increased when combined with Secobarbital.
Sodium Oxybate	Sodium Oxybate Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate.
Isocarboxazid	Isocarboxazid Secobarbital may increase the hypotensive activities of Isocarboxazid.
Ramelteon	Ramelteon The risk or severity of adverse effects can be increased when Secobarbital is combined with Ramelteon.
Darifenacin	Darifenacin Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Darifenacin.
Fentanyl	Fentanyl The risk or severity of adverse effects can be increased when Secobarbital is combined with Fentanyl.
Pregabalin	Pregabalin The therapeutic efficacy of Secobarbital can be increased when used in combination with Pregabalin.
Felbamate	Felbamate The serum concentration of Secobarbital can be increased when it is combined with Felbamate.
Ranolazine	Ranolazine The metabolism of Secobarbital can be increased when combined with Ranolazine.
Rasagiline	Rasagiline Secobarbital may increase the hypotensive activities of Rasagiline.
Imatinib	Imatinib The metabolism of Imatinib can be increased when combined with Secobarbital.
Sitagliptin	Sitagliptin The metabolism of Sitagliptin can be increased when combined with Secobarbital.
Varenicline	Varenicline Secobarbital may decrease the excretion rate of Varenicline which could result in a higher serum level.
Albuterol	Albuterol Secobarbital may decrease the excretion rate of Salbutamol which could result in a higher serum level.
Paliperidone	Paliperidone The risk or severity of adverse effects can be increased when Secobarbital is combined with Paliperidone.
Bortezomib	Bortezomib The metabolism of Bortezomib can be increased when combined with Secobarbital.
Clofarabine Injection	Clofarabine Injection Secobarbital may increase the hypotensive activities of Clofarabine.
Lubiprostone	Lubiprostone Secobarbital may decrease the excretion rate of Lubiprostone which could result in a higher serum level.
Primaquine	Primaquine The metabolism of Primaquine can be increased when combined with Secobarbital.
Aliskiren	Aliskiren Secobarbital may increase the hypotensive activities of Aliskiren.
Pemetrexed Injection	Pemetrexed Injection Secobarbital may decrease the excretion rate of Pemetrexed which could result in a higher serum level.
Dimenhydrinate	Dimenhydrinate The risk or severity of adverse effects can be increased when Secobarbital is combined with Dimenhydrinate.
Nabilone	Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Secobarbital.
Retapamulin	Retapamulin The metabolism of Retapamulin can be increased when combined with Secobarbital.
Sorafenib	Sorafenib The metabolism of Sorafenib can be increased when combined with Secobarbital.
Sunitinib	Sunitinib The metabolism of Sunitinib can be increased when combined with Secobarbital.
Dronabinol	Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Secobarbital.
Lapatinib	Lapatinib The metabolism of Lapatinib can be increased when combined with Secobarbital.
Levocetirizine	Levocetirizine The risk or severity of adverse effects can be increased when Secobarbital is combined with Levocetirizine.
Pegaptanib Injection	Pegaptanib Injection Secobarbital may decrease the excretion rate of Pegaptanib which could result in a higher serum level.
Dasatinib	Dasatinib The metabolism of Dasatinib can be increased when combined with Secobarbital.
Mexiletine	Mexiletine The metabolism of Mexiletine can be increased when combined with Secobarbital.
Azacitidine Injection	Azacitidine Injection Secobarbital may decrease the excretion rate of Azacitidine which could result in a higher serum level.
Paclitaxel (with polyoxyethylated castor oil) Injection	Paclitaxel (with polyoxyethylated castor oil) Injection The therapeutic efficacy of Castor oil can be decreased when used in combination with Secobarbital.
Temsirolimus	Temsirolimus The metabolism of Temsirolimus can be increased when combined with Secobarbital.
Lenalidomide	Lenalidomide Secobarbital may decrease the excretion rate of Lenalidomide which could result in a higher serum level.
Nilotinib	Nilotinib The metabolism of Nilotinib can be increased when combined with Secobarbital.
Budesonide	Budesonide Secobarbital may decrease the excretion rate of Budesonide which could result in a higher serum level.
Chloramphenicol Injection	Chloramphenicol Injection The metabolism of Secobarbital can be decreased when combined with Chloramphenicol.
Desmopressin	Desmopressin Desmopressin may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Betaine	Betaine The therapeutic efficacy of Secobarbital can be decreased when used in combination with Glycine betaine.
OnabotulinumtoxinA Injection	OnabotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Secobarbital is combined with Botulinum toxin type A.
RimabotulinumtoxinB Injection	RimabotulinumtoxinB Injection The risk or severity of adverse effects can be increased when Secobarbital is combined with Botulinum Toxin Type B.
Doripenem Injection	Doripenem Injection Secobarbital may decrease the excretion rate of Doripenem which could result in a higher serum level.
Arsenic Trioxide Injection	Arsenic Trioxide Injection Secobarbital may increase the hypotensive activities of Arsenic trioxide.
Desvenlafaxine	Desvenlafaxine The risk or severity of adverse effects can be increased when Secobarbital is combined with Desvenlafaxine.
Cevimeline	Cevimeline Cevimeline may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Nebivolol	Nebivolol The serum concentration of Nebivolol can be decreased when it is combined with Secobarbital.
Tretinoin	Tretinoin The metabolism of Tretinoin can be increased when combined with Secobarbital.
Bendamustine Injection	Bendamustine Injection The metabolism of Bendamustine can be increased when combined with Secobarbital.
Flecainide	Flecainide The metabolism of Flecainide can be increased when combined with Secobarbital.
Certolizumab Injection	Certolizumab Injection Secobarbital may decrease the excretion rate of Certolizumab pegol which could result in a higher serum level.
Ixabepilone Injection	Ixabepilone Injection The metabolism of Ixabepilone can be increased when combined with Secobarbital.
Irinotecan Injection	Irinotecan Injection The metabolism of Irinotecan can be increased when combined with Secobarbital.
Daptomycin Injection	Daptomycin Injection Daptomycin may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Praziquantel	Praziquantel The metabolism of Praziquantel can be increased when combined with Secobarbital.
Methylnaltrexone Injection	Methylnaltrexone Injection Secobarbital may decrease the excretion rate of Methylnaltrexone which could result in a higher serum level.
Rufinamide	Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Secobarbital.
Midazolam	Midazolam The risk or severity of adverse effects can be increased when Secobarbital is combined with Midazolam.
Naltrexone Injection	Naltrexone Injection The risk or severity of adverse effects can be increased when Secobarbital is combined with Naltrexone.
Dexrazoxane Injection	Dexrazoxane Injection Dexrazoxane may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Eltrombopag	Eltrombopag The metabolism of Eltrombopag can be increased when combined with Secobarbital.
Milnacipran	Milnacipran The metabolism of Milnacipran can be increased when combined with Secobarbital.
Plerixafor Injection	Plerixafor Injection Secobarbital may decrease the excretion rate of Plerixafor which could result in a higher serum level.
Sodium Phosphate	Sodium Phosphate The therapeutic efficacy of Secobarbital can be decreased when used in combination with Sodium phosphate, monobasic.
Fesoterodine	Fesoterodine Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Fesoterodine.
Betaxolol	Betaxolol The serum concentration of Betaxolol can be decreased when it is combined with Secobarbital.
Iloperidone	Iloperidone The risk or severity of adverse effects can be increased when Secobarbital is combined with Iloperidone.
Prasugrel	Prasugrel Secobarbital may decrease the excretion rate of Prasugrel which could result in a higher serum level.
Lacosamide	Lacosamide The risk or severity of adverse effects can be increased when Secobarbital is combined with Lacosamide.
Everolimus	Everolimus The metabolism of Everolimus can be increased when combined with Secobarbital.
Tolvaptan (low blood sodium)	Tolvaptan (low blood sodium) The metabolism of Secobarbital can be increased when combined with Tolvaptan.
Dronedarone	Dronedarone The metabolism of Dronedarone can be increased when combined with Secobarbital.
AbobotulinumtoxinA Injection	AbobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Secobarbital is combined with Botulinum toxin type A.
Pralatrexate Injection	Pralatrexate Injection Secobarbital may decrease the excretion rate of Pralatrexate which could result in a higher serum level.
Palonosetron Injection	Palonosetron Injection The risk or severity of adverse effects can be increased when Palonosetron is combined with Secobarbital.
Saxagliptin	Saxagliptin Secobarbital may decrease the excretion rate of Saxagliptin which could result in a higher serum level.
Telavancin Injection	Telavancin Injection Secobarbital may decrease the excretion rate of Telavancin which could result in a higher serum level.
Romidepsin Injection	Romidepsin Injection The metabolism of Romidepsin can be increased when combined with Secobarbital.
Tapentadol	Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Secobarbital.
Topotecan	Topotecan Secobarbital may increase the excretion rate of Topotecan which could result in a lower serum level and potentially a reduction in efficacy.
Pazopanib	Pazopanib The metabolism of Pazopanib can be increased when combined with Secobarbital.
Asenapine	Asenapine The risk or severity of adverse effects can be increased when Secobarbital is combined with Asenapine.
Vigabatrin	Vigabatrin The risk or severity of adverse effects can be increased when Secobarbital is combined with Vigabatrin.
Pitavastatin	Pitavastatin The metabolism of Pitavastatin can be increased when combined with Secobarbital.
Albendazole	Albendazole The metabolism of Albendazole can be increased when combined with Secobarbital.
Ulipristal	Ulipristal The serum concentration of Ulipristal can be decreased when it is combined with Secobarbital.
Levonorgestrel	Levonorgestrel The metabolism of Levonorgestrel can be increased when combined with Secobarbital.
Oxymorphone	Oxymorphone The risk or severity of adverse effects can be increased when Secobarbital is combined with Oxymorphone.
Dalfampridine	Dalfampridine Secobarbital may decrease the excretion rate of Dalfampridine which could result in a higher serum level.
IncobotulinumtoxinA Injection	IncobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Secobarbital is combined with Botulinum toxin type A.
Cabazitaxel Injection	Cabazitaxel Injection The metabolism of Cabazitaxel can be increased when combined with Secobarbital.
Ceftaroline Injection	Ceftaroline Injection Ceftaroline fosamil may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Lurasidone	Lurasidone The risk or severity of adverse effects can be increased when Secobarbital is combined with Lurasidone.
Acetaminophen Injection	Acetaminophen Injection The metabolism of Secobarbital can be increased when combined with Acetaminophen.
Vilazodone	Vilazodone The risk or severity of adverse effects can be increased when Secobarbital is combined with Vilazodone.
Ipilimumab Injection	Ipilimumab Injection Secobarbital may decrease the excretion rate of Ipilimumab which could result in a higher serum level.
Denileukin Diftitox Injection	Denileukin Diftitox Injection Secobarbital may increase the hypotensive activities of Aldesleukin.
Terbutaline Injection	Terbutaline Injection The therapeutic efficacy of Secobarbital can be decreased when used in combination with Terbutaline.
Azilsartan	Azilsartan Secobarbital may increase the hypotensive activities of Azilsartan medoxomil.
Busulfan Injection	Busulfan Injection The metabolism of Busulfan can be increased when combined with Secobarbital.
Roflumilast	Roflumilast The metabolism of Roflumilast can be increased when combined with Secobarbital.
Linagliptin	Linagliptin The metabolism of Linagliptin can be increased when combined with Secobarbital.
Cyclophosphamide Injection	Cyclophosphamide Injection The metabolism of Cyclophosphamide can be increased when combined with Secobarbital.
Rivaroxaban	Rivaroxaban Secobarbital may decrease the excretion rate of Rivaroxaban which could result in a higher serum level.
Brentuximab Vedotin Injection	Brentuximab Vedotin Injection The metabolism of Brentuximab vedotin can be increased when combined with Secobarbital.
Ruxolitinib	Ruxolitinib The metabolism of Ruxolitinib can be increased when combined with Secobarbital.
Vandetanib	Vandetanib The metabolism of Vandetanib can be increased when combined with Secobarbital.
Clobazam	Clobazam The risk or severity of adverse effects can be increased when Clobazam is combined with Secobarbital.
Vemurafenib	Vemurafenib The metabolism of Vemurafenib can be increased when combined with Secobarbital.
Deferiprone	Deferiprone Secobarbital may decrease the excretion rate of Deferiprone which could result in a higher serum level.
Axitinib	Axitinib The metabolism of Axitinib can be increased when combined with Secobarbital.
Crizotinib	Crizotinib The metabolism of Crizotinib can be increased when combined with Secobarbital.
Cabergoline	Cabergoline The metabolism of Secobarbital can be increased when combined with Cabergoline.
Naloxone Injection	Naloxone Injection Secobarbital may decrease the excretion rate of Naloxone which could result in a higher serum level.
Fondaparinux Injection	Fondaparinux Injection Secobarbital may decrease the excretion rate of Fondaparinux which could result in a higher serum level.
Ezogabine	Ezogabine The risk or severity of adverse effects can be increased when Secobarbital is combined with Tiagabine.
Iloprost	Iloprost Secobarbital may increase the hypotensive activities of Iloprost.
Enzalutamide	Enzalutamide The metabolism of Enzalutamide can be increased when combined with Secobarbital.
Mirabegron	Mirabegron Secobarbital may decrease the excretion rate of Mirabegron which could result in a higher serum level.
Regorafenib	Regorafenib The metabolism of Regorafenib can be increased when combined with Secobarbital.
Bosutinib	Bosutinib The metabolism of Bosutinib can be increased when combined with Secobarbital.
Linaclotide	Linaclotide The therapeutic efficacy of Linaclotide can be decreased when used in combination with Secobarbital.
Cabozantinib (thyroid cancer)	Cabozantinib (thyroid cancer) The metabolism of Cabozantinib can be increased when combined with Secobarbital.
Teduglutide Injection	Teduglutide Injection Secobarbital may decrease the excretion rate of Teduglutide which could result in a higher serum level.
Alogliptin	Alogliptin Secobarbital may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Ponatinib	Ponatinib The metabolism of Ponatinib can be increased when combined with Secobarbital.
Pomalidomide	Pomalidomide The metabolism of Pomalidomide can be increased when combined with Secobarbital.
Ado-trastuzumab Emtansine Injection	Ado-trastuzumab Emtansine Injection The metabolism of Trastuzumab emtansine can be increased when combined with Secobarbital.
Apixaban	Apixaban The metabolism of Apixaban can be increased when combined with Secobarbital.
Canagliflozin	Canagliflozin The serum concentration of Canagliflozin can be decreased when it is combined with Secobarbital.
Methazolamide	Methazolamide Secobarbital may increase the hypotensive activities of Methazolamide.
Dabrafenib	Dabrafenib The metabolism of Dabrafenib can be increased when combined with Secobarbital.
Trametinib	Trametinib Secobarbital may decrease the excretion rate of Trametinib which could result in a higher serum level.
Levomilnacipran	Levomilnacipran The metabolism of Levomilnacipran can be increased when combined with Secobarbital.
Ertapenem Injection	Ertapenem Injection Ertapenem may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Vortioxetine	Vortioxetine The metabolism of Vortioxetine can be increased when combined with Secobarbital.
Perampanel	Perampanel The metabolism of Perampanel can be increased when combined with Secobarbital.
Lomitapide	Lomitapide The metabolism of Lomitapide can be increased when combined with Secobarbital.
Ketorolac Injection	Ketorolac Injection The metabolism of Secobarbital can be increased when combined with Ketorolac.
Obinutuzumab Injection	Obinutuzumab Injection Secobarbital may increase the hypotensive activities of Obinutuzumab.
Sofosbuvir	Sofosbuvir Secobarbital may decrease the excretion rate of Sofosbuvir which could result in a higher serum level.
Dapagliflozin	Dapagliflozin Secobarbital may increase the hypotensive activities of Dapagliflozin.
Apremilast	Apremilast The metabolism of Apremilast can be increased when combined with Secobarbital.
Droxidopa	Droxidopa Secobarbital may decrease the excretion rate of Droxidopa which could result in a higher serum level.
Ceritinib	Ceritinib The metabolism of Ceritinib can be increased when combined with Secobarbital.
Eslicarbazepine	Eslicarbazepine The risk or severity of adverse effects can be increased when Secobarbital is combined with Eslicarbazepine.
Idelalisib	Idelalisib The metabolism of Idelalisib can be increased when combined with Secobarbital.
Testosterone Injection	Testosterone Injection Secobarbital may decrease the excretion rate of Testosterone which could result in a higher serum level.
Empagliflozin	Empagliflozin Secobarbital may increase the hypotensive activities of Empagliflozin.
Vorapaxar	Vorapaxar The metabolism of Vorapaxar can be increased when combined with Secobarbital.
Hydrocodone	Hydrocodone Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone.
Suvorexant	Suvorexant Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Edoxaban	Edoxaban Secobarbital may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Olaparib	Olaparib The metabolism of Olaparib can be increased when combined with Secobarbital.
Methamphetamine	Methamphetamine The risk or severity of adverse effects can be increased when Secobarbital is combined with Metamfetamine.
Tasimelteon	Tasimelteon The risk or severity of adverse effects can be increased when Secobarbital is combined with Tasimelteon.
Riociguat	Riociguat The metabolism of Riociguat can be increased when combined with Secobarbital.
Pirfenidone	Pirfenidone The metabolism of Pirfenidone can be increased when combined with Secobarbital.
Nintedanib	Nintedanib The metabolism of Nintedanib can be increased when combined with Secobarbital.
Risperidone Injection	Risperidone Injection The risk or severity of adverse effects can be increased when Secobarbital is combined with Risperidone.
Palbociclib	Palbociclib The metabolism of Palbociclib can be increased when combined with Secobarbital.
Panobinostat	Panobinostat The metabolism of Panobinostat can be increased when combined with Secobarbital.
Dinutuximab Injection	Dinutuximab Injection Secobarbital may increase the hypotensive activities of Dinutuximab.
Haloperidol Injection	Haloperidol Injection The risk or severity of CNS depression can be increased when Secobarbital is combined with Haloperidol.
Amiloride	Amiloride Secobarbital may increase the hypotensive activities of Amiloride.
Macitentan	Macitentan Secobarbital may decrease the excretion rate of Macitentan which could result in a higher serum level.
Sonidegib	Sonidegib The metabolism of Sonidegib can be increased when combined with Secobarbital.
Flibanserin	Flibanserin The risk or severity of adverse effects can be increased when Secobarbital is combined with Flibanserin.
Brexpiprazole	Brexpiprazole The risk or severity of adverse effects can be increased when Secobarbital is combined with Brexpiprazole.
Ziprasidone Injection	Ziprasidone Injection The risk or severity of adverse effects can be increased when Ziprasidone is combined with Secobarbital.
Cariprazine	Cariprazine The risk or severity of adverse effects can be increased when Secobarbital is combined with Cariprazine.
Penicillin G Procaine Injection	Penicillin G Procaine Injection Secobarbital may decrease the excretion rate of Procaine benzylpenicillin which could result in a higher serum level.
Eluxadoline	Eluxadoline The risk or severity of constipation can be increased when Secobarbital is combined with Eluxadoline.
Cobimetinib	Cobimetinib The metabolism of Cobimetinib can be increased when combined with Secobarbital.
Trabectedin Injection	Trabectedin Injection The metabolism of Trabectedin can be increased when combined with Secobarbital.
Osimertinib	Osimertinib The metabolism of Osimertinib can be increased when combined with Secobarbital.
Alectinib	Alectinib The metabolism of Alectinib can be increased when combined with Secobarbital.
Ixazomib	Ixazomib The metabolism of Ixazomib can be increased when combined with Secobarbital.
Lesinurad	Lesinurad Secobarbital may decrease the excretion rate of Lesinurad which could result in a higher serum level.
Amphotericin B Liposomal Injection	Amphotericin B Liposomal Injection Secobarbital may increase the hypotensive activities of Amphotericin B.
Brivaracetam Injection	Brivaracetam Injection The risk or severity of adverse effects can be increased when Secobarbital is combined with Brivaracetam.
Venetoclax	Venetoclax The metabolism of Venetoclax can be increased when combined with Secobarbital.
Selexipag	Selexipag The metabolism of Selexipag can be increased when combined with Secobarbital.
Pimavanserin	Pimavanserin The risk or severity of adverse effects can be increased when Secobarbital is combined with Pimavanserin.
Diphenhydramine Injection	Diphenhydramine Injection The risk or severity of adverse effects can be increased when Secobarbital is combined with Diphenhydramine.
Furosemide Injection	Furosemide Injection Secobarbital may increase the hypotensive activities of Furosemide.
Rucaparib	Rucaparib The metabolism of Rucaparib can be increased when combined with Secobarbital.
Lixisenatide Injection	Lixisenatide Injection Secobarbital may decrease the excretion rate of Lixisenatide which could result in a higher serum level.
Ribociclib	Ribociclib The metabolism of Ribociclib can be increased when combined with Secobarbital.
Brigatinib	Brigatinib The metabolism of Brigatinib can be increased when combined with Secobarbital.
Doxepin (Insomnia)	Doxepin (Insomnia) Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Doxepin.
Plecanatide	Plecanatide The therapeutic efficacy of Plecanatide can be decreased when used in combination with Secobarbital.
Deutetrabenazine	Deutetrabenazine The risk or severity of sedation and somnolence can be increased when Secobarbital is combined with Deutetrabenazine.
Valbenazine	Valbenazine Secobarbital may decrease the excretion rate of Valbenazine which could result in a higher serum level.
Safinamide	Safinamide The risk or severity of adverse effects can be increased when Secobarbital is combined with Safinamide.
Naldemedine	Naldemedine Secobarbital may decrease the excretion rate of Naldemedine which could result in a higher serum level.
Midostaurin	Midostaurin The metabolism of Midostaurin can be increased when combined with Secobarbital.
Neratinib	Neratinib The metabolism of Neratinib can be increased when combined with Secobarbital.
Enasidenib	Enasidenib The metabolism of Enasidenib can be increased when combined with Secobarbital.
Aprepitant/Fosaprepitant Injection	Aprepitant/Fosaprepitant Injection The metabolism of Fosaprepitant can be increased when combined with Secobarbital.
Benznidazole	Benznidazole Secobarbital may decrease the excretion rate of Benznidazole which could result in a higher serum level.
Copanlisib Injection	Copanlisib Injection The metabolism of Copanlisib can be increased when combined with Secobarbital.
Delafloxacin	Delafloxacin Secobarbital may decrease the excretion rate of Delafloxacin which could result in a higher serum level.
Abemaciclib	Abemaciclib The metabolism of Abemaciclib can be increased when combined with Secobarbital.
Acalabrutinib	Acalabrutinib The metabolism of Acalabrutinib can be increased when combined with Secobarbital.
Tetrabenazine	Tetrabenazine The risk or severity of sedation and somnolence can be increased when Secobarbital is combined with Tetrabenazine.
Ertugliflozin	Ertugliflozin Ertugliflozin may increase the excretion rate of Secobarbital which could result in a lower serum level and potentially a reduction in efficacy.
Buprenorphine Injection	Buprenorphine Injection Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Apalutamide	Apalutamide The metabolism of Apalutamide can be increased when combined with Secobarbital.
Baricitinib	Baricitinib The metabolism of Baricitinib can be increased when combined with Secobarbital.
Lofexidine	Lofexidine The therapeutic efficacy of Secobarbital can be increased when used in combination with Lofexidine.
Plazomicin Injection	Plazomicin Injection Secobarbital may decrease the excretion rate of Plazomicin which could result in a higher serum level.
Binimetinib	Binimetinib The metabolism of Binimetinib can be increased when combined with Secobarbital.
Ivosidenib	Ivosidenib The metabolism of Ivosidenib can be increased when combined with Secobarbital.
Elagolix	Elagolix The metabolism of Elagolix can be increased when combined with Secobarbital.
Cannabidiol	Cannabidiol The risk or severity of adverse effects can be increased when Cannabidiol is combined with Secobarbital.
Dacomitinib	Dacomitinib The metabolism of Dacomitinib can be increased when combined with Secobarbital.
Duvelisib	Duvelisib The metabolism of Duvelisib can be increased when combined with Secobarbital.
Stiripentol	Stiripentol The risk or severity of adverse effects can be increased when Secobarbital is combined with Stiripentol.
Gilteritinib	Gilteritinib The metabolism of Gilteritinib can be increased when combined with Secobarbital.
Glasdegib	Glasdegib The metabolism of Glasdegib can be increased when combined with Secobarbital.
Lorlatinib	Lorlatinib The metabolism of Lorlatinib can be increased when combined with Secobarbital.
Paclitaxel (with albumin) Injection	Paclitaxel (with albumin) Injection The metabolism of Paclitaxel can be increased when combined with Secobarbital.
Prucalopride	Prucalopride The metabolism of Prucalopride can be increased when combined with Secobarbital.
Magnesium Citrate	Magnesium Citrate The therapeutic efficacy of Magnesium citrate can be decreased when used in combination with Secobarbital.
Siponimod	Siponimod The metabolism of Siponimod can be increased when combined with Secobarbital.
Acyclovir Ophthalmic	Acyclovir Ophthalmic Acyclovir may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Erdafitinib	Erdafitinib The metabolism of Erdafitinib can be increased when combined with Secobarbital.
Alpelisib	Alpelisib The metabolism of Alpelisib can be increased when combined with Secobarbital.
Brexanolone Injection	Brexanolone Injection The risk or severity of adverse effects can be increased when Secobarbital is combined with Brexanolone.
Solriamfetol	Solriamfetol The risk or severity of adverse effects can be increased when Secobarbital is combined with Solriamfetol.
Triclabendazole	Triclabendazole The metabolism of Triclabendazole can be increased when combined with Secobarbital.
Entrectinib	Entrectinib The metabolism of Entrectinib can be increased when combined with Secobarbital.
Pexidartinib	Pexidartinib The metabolism of Pexidartinib can be increased when combined with Secobarbital.
Istradefylline	Istradefylline The metabolism of Istradefylline can be increased when combined with Secobarbital.
Pitolisant	Pitolisant Secobarbital may decrease the excretion rate of Pitolisant which could result in a higher serum level.
Lefamulin	Lefamulin The metabolism of Lefamulin can be increased when combined with Secobarbital.
Phenytoin Injection	Phenytoin Injection The metabolism of Phenytoin can be increased when combined with Secobarbital.
Fosphenytoin Injection	Fosphenytoin Injection The metabolism of Fosphenytoin can be increased when combined with Secobarbital.
Zanubrutinib	Zanubrutinib The metabolism of Zanubrutinib can be increased when combined with Secobarbital.
Lumateperone	Lumateperone The serum concentration of Lumateperone can be decreased when it is combined with Secobarbital.
Lasmiditan	Lasmiditan The risk or severity of adverse effects can be increased when Secobarbital is combined with Lasmiditan.
Tazemetostat	Tazemetostat The metabolism of Tazemetostat can be increased when combined with Secobarbital.
Ozanimod	Ozanimod The metabolism of Ozanimod can be increased when combined with Secobarbital.
Selumetinib	Selumetinib The metabolism of Selumetinib can be increased when combined with Secobarbital.
Rimegepant	Rimegepant The metabolism of Rimegepant can be increased when combined with Secobarbital.
Tucatinib	Tucatinib The metabolism of Tucatinib can be increased when combined with Secobarbital.
Selpercatinib	Selpercatinib The serum concentration of Selpercatinib can be decreased when it is combined with Secobarbital.
Capmatinib	Capmatinib The serum concentration of Capmatinib can be decreased when it is combined with Secobarbital.
Lemborexant	Lemborexant The serum concentration of Lemborexant can be decreased when it is combined with Secobarbital.
Fenfluramine	Fenfluramine The risk or severity of adverse effects can be increased when Secobarbital is combined with Fenfluramine.
Progestin-Only (drospirenone) Oral Contraceptives	Progestin-Only (drospirenone) Oral Contraceptives The metabolism of Drospirenone can be increased when combined with Secobarbital.
Viloxazine	Viloxazine The risk or severity of adverse effects can be increased when Secobarbital is combined with Viloxazine.
Tobramycin Injection	Tobramycin Injection Tobramycin may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Theophylline	Theophylline The metabolism of Theophylline can be increased when combined with Secobarbital.
Fenoprofen	Fenoprofen Fenoprofen may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Indomethacin	Indomethacin Indomethacin may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Mefenamic Acid	Mefenamic Acid Mefenamic acid may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Naproxen	Naproxen The metabolism of Naproxen can be increased when combined with Secobarbital.
Tolmetin	Tolmetin Tolmetin may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Sulindac	Sulindac Sulindac may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Trazodone	Trazodone The risk or severity of adverse effects can be increased when Secobarbital is combined with Trazodone.
Isotretinoin	Isotretinoin Secobarbital may decrease the excretion rate of Isotretinoin which could result in a higher serum level.
Sucralfate	Sucralfate Sucralfate may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Floxuridine	Floxuridine Floxuridine may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Phenobarbital	Phenobarbital The metabolism of Phenobarbital can be increased when combined with Secobarbital.
Metaxalone	Metaxalone The risk or severity of adverse effects can be increased when Secobarbital is combined with Metaxalone.
Methotrexate Injection	Methotrexate Injection The metabolism of Secobarbital can be increased when combined with Methotrexate.
Levorphanol	Levorphanol The risk or severity of adverse effects can be increased when Secobarbital is combined with Levorphanol.
Primidone	Primidone The risk or severity of adverse effects can be increased when Primidone is combined with Secobarbital.
Methsuximide	Methsuximide The risk or severity of adverse effects can be increased when Secobarbital is combined with Methsuximide.
Diethylpropion	Diethylpropion The risk or severity of adverse effects can be increased when Secobarbital is combined with Diethylpropion.
Chlorpromazine	Chlorpromazine The metabolism of Secobarbital can be increased when combined with Chlorpromazine.
Diazepam	Diazepam The risk or severity of adverse effects can be increased when Secobarbital is combined with Diazepam.
Oxazepam	Oxazepam The risk or severity of adverse effects can be increased when Secobarbital is combined with Oxazepam.
Flurazepam	Flurazepam The risk or severity of adverse effects can be increased when Secobarbital is combined with Flurazepam.
Clorazepate	Clorazepate The risk or severity of adverse effects can be increased when Secobarbital is combined with Clorazepic acid.
Lorazepam	Lorazepam The risk or severity of adverse effects can be increased when Lorazepam is combined with Secobarbital.
Phenoxybenzamine	Phenoxybenzamine Secobarbital may increase the hypotensive activities of Phenoxybenzamine.
Carmustine	Carmustine The metabolism of Secobarbital can be increased when combined with Carmustine.
Amantadine	Amantadine Secobarbital may decrease the excretion rate of Amantadine which could result in a higher serum level.
Codeine	Codeine The risk or severity of adverse effects can be increased when Secobarbital is combined with Codeine.
Meprobamate	Meprobamate The risk or severity of adverse effects can be increased when Meprobamate is combined with Secobarbital.
Chlordiazepoxide	Chlordiazepoxide The risk or severity of adverse effects can be increased when Secobarbital is combined with Chlordiazepoxide.
Bromocriptine	Bromocriptine The risk or severity of adverse effects can be increased when Secobarbital is combined with Bromocriptine.
Tranylcypromine	Tranylcypromine Secobarbital may increase the hypotensive activities of Tranylcypromine.
Phenelzine	Phenelzine Secobarbital may increase the hypotensive activities of Phenelzine.
Procarbazine	Procarbazine The risk or severity of adverse effects can be increased when Secobarbital is combined with Procarbazine.
Ergoloid Mesylates	Ergoloid Mesylates The risk or severity of adverse effects can be increased when Secobarbital is combined with Ergoloid mesylate.
Tetracycline	Tetracycline Secobarbital may decrease the excretion rate of Tetracycline which could result in a higher serum level.
Minocycline	Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Secobarbital.
Prochlorperazine	Prochlorperazine The risk or severity of adverse effects can be increased when Secobarbital is combined with Prochlorperazine.
Thioridazine	Thioridazine The risk or severity of adverse effects can be increased when Secobarbital is combined with Thioridazine.
Trifluoperazine	Trifluoperazine The risk or severity of adverse effects can be increased when Secobarbital is combined with Trifluoperazine.
Bleomycin	Bleomycin Bleomycin may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Dapsone	Dapsone The metabolism of Dapsone can be increased when combined with Secobarbital.
Sulfadiazine	Sulfadiazine The metabolism of Sulfadiazine can be increased when combined with Secobarbital.
Oxycodone	Oxycodone The risk or severity of adverse effects can be increased when Secobarbital is combined with Oxycodone.
Methadone	Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Secobarbital.
Oxybutynin	Oxybutynin Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Oxybutynin.
Benztropine	Benztropine Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Benzatropine.
Maprotiline	Maprotiline Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Maprotiline.
Ibuprofen	Ibuprofen The metabolism of Ibuprofen can be increased when combined with Secobarbital.
Trihexyphenidyl	Trihexyphenidyl Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Trihexyphenidyl.
Orphenadrine	Orphenadrine Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Perphenazine	Perphenazine The metabolism of Perphenazine can be increased when combined with Secobarbital.
Azathioprine	Azathioprine The metabolism of Azathioprine can be increased when combined with Secobarbital.
Fluphenazine	Fluphenazine The risk or severity of adverse effects can be increased when Secobarbital is combined with Fluphenazine.
Phentermine	Phentermine The metabolism of Phentermine can be increased when combined with Secobarbital.
Methylphenidate	Methylphenidate The therapeutic efficacy of Methylphenidate can be decreased when used in combination with Secobarbital.
Amoxapine	Amoxapine The metabolism of Amoxapine can be increased when combined with Secobarbital.
Sulfasalazine	Sulfasalazine Sulfasalazine may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Doxorubicin	Doxorubicin The metabolism of Doxorubicin can be increased when combined with Secobarbital.
Mechlorethamine	Mechlorethamine The therapeutic efficacy of Secobarbital can be decreased when used in combination with Mechlorethamine.
Pyridostigmine	Pyridostigmine The therapeutic efficacy of Secobarbital can be decreased when used in combination with Pyridostigmine.
Phenazopyridine	Phenazopyridine Phenazopyridine may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Carbamazepine	Carbamazepine Carbamazepine may increase the Change in thyroid function activities of Secobarbital.
Molindone	Molindone The risk or severity of adverse effects can be increased when Secobarbital is combined with Molindone.
Methyldopa	Methyldopa Secobarbital may increase the hypotensive activities of Methyldopa.
Clonidine	Clonidine The risk or severity of sedation can be increased when Clonidine is combined with Secobarbital.
Prazosin	Prazosin Secobarbital may increase the hypotensive activities of Prazosin.
Hydralazine	Hydralazine Secobarbital may increase the hypotensive activities of Hydralazine.
Cimetidine	Cimetidine Secobarbital may decrease the excretion rate of Cimetidine which could result in a higher serum level.
Gentamicin Injection	Gentamicin Injection Gentamicin may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Warfarin	Warfarin The metabolism of Warfarin can be increased when combined with Secobarbital.
Clonazepam	Clonazepam The metabolism of Clonazepam can be increased when combined with Secobarbital.
Loperamide	Loperamide The metabolism of Loperamide can be increased when combined with Secobarbital.
Promethazine	Promethazine The risk or severity of adverse effects can be increased when Secobarbital is combined with Promethazine.
Meclofenamate	Meclofenamate Meclofenamic acid may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Nitrofurantoin	Nitrofurantoin Secobarbital may decrease the excretion rate of Nitrofurantoin which could result in a higher serum level.
Griseofulvin	Griseofulvin The serum concentration of Griseofulvin can be decreased when it is combined with Secobarbital.
Digoxin	Digoxin Secobarbital may decrease the excretion rate of Digoxin which could result in a higher serum level.
Loxapine	Loxapine The risk or severity of adverse effects can be increased when Loxapine is combined with Secobarbital.
Chloroquine	Chloroquine The metabolism of Chloroquine can be increased when combined with Secobarbital.
Quinine	Quinine The metabolism of Quinine can be increased when combined with Secobarbital.
Ethosuximide	Ethosuximide The risk or severity of adverse effects can be increased when Secobarbital is combined with Ethosuximide.
Triamterene	Triamterene Secobarbital may increase the hypotensive activities of Triamterene.
Lactulose	Lactulose The therapeutic efficacy of Lactulose can be decreased when used in combination with Secobarbital.
Chlorothiazide	Chlorothiazide The risk or severity of hypotension and orthostatic hypotension can be increased when Secobarbital is combined with Chlorothiazide.
Chlorthalidone	Chlorthalidone The risk or severity of hypotension and orthostatic hypotension can be increased when Secobarbital is combined with Chlorthalidone.
Metolazone	Metolazone The risk or severity of hypotension and orthostatic hypotension can be increased when Secobarbital is combined with Metolazone.
Isosorbide	Isosorbide The metabolism of Isosorbide can be increased when combined with Secobarbital.
Clindamycin Injection	Clindamycin Injection The metabolism of Clindamycin can be increased when combined with Secobarbital.
Desipramine	Desipramine Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Desipramine.
Amitriptyline	Amitriptyline The metabolism of Amitriptyline can be increased when combined with Secobarbital.
Imipramine	Imipramine The metabolism of Imipramine can be increased when combined with Secobarbital.
Probenecid	Probenecid Secobarbital may decrease the excretion rate of Probenecid which could result in a higher serum level.
Quinidine	Quinidine The metabolism of Quinidine can be increased when combined with Secobarbital.
Procainamide	Procainamide Procainamide may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Isoniazid	Isoniazid The therapeutic efficacy of Isoniazid can be decreased when used in combination with Secobarbital.
Pyrazinamide	Pyrazinamide Pyrazinamide may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Disopyramide	Disopyramide Disopyramide may increase the central nervous system depressant (CNS depressant) activities of Secobarbital.
Valproic Acid	Valproic Acid The serum concentration of Secobarbital can be increased when it is combined with Valproic acid.
Tamoxifen	Tamoxifen The metabolism of Tamoxifen can be increased when combined with Secobarbital.
Butabarbital	Butabarbital The risk or severity of adverse effects can be increased when Butabarbital is combined with Secobarbital.
Liothyronine	Liothyronine Liothyronine may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Methimazole	Methimazole Secobarbital may decrease the excretion rate of Methimazole which could result in a higher serum level.
Chlorpropamide	Chlorpropamide Secobarbital may decrease the excretion rate of Chlorpropamide which could result in a higher serum level.
Tolbutamide	Tolbutamide The metabolism of Tolbutamide can be increased when combined with Secobarbital.
Tolazamide	Tolazamide Secobarbital may decrease the excretion rate of Tolazamide which could result in a higher serum level.
Dextromethorphan	Dextromethorphan The risk or severity of adverse effects can be increased when Secobarbital is combined with Dextromethorphan.
Cyclobenzaprine	Cyclobenzaprine The risk or severity of CNS depression can be increased when Secobarbital is combined with Cyclobenzaprine.
Baclofen	Baclofen The risk or severity of adverse effects can be increased when Baclofen is combined with Secobarbital.
Doxylamine	Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Secobarbital.
Cyproheptadine	Cyproheptadine Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Cyproheptadine.
Clemastine	Clemastine The risk or severity of adverse effects can be increased when Clemastine is combined with Secobarbital.
Chlorpheniramine	Chlorpheniramine The risk or severity of adverse effects can be increased when Secobarbital is combined with Chlorpheniramine.
Brompheniramine	Brompheniramine The risk or severity of adverse effects can be increased when Dexbrompheniramine is combined with Secobarbital.
Meclizine	Meclizine The risk or severity of adverse effects can be increased when Secobarbital is combined with Meclizine.
Ethambutol	Ethambutol Ethambutol may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Methyclothiazide	Methyclothiazide The risk or severity of hypotension and orthostatic hypotension can be increased when Secobarbital is combined with Methyclothiazide.
Hydrochlorothiazide	Hydrochlorothiazide The risk or severity of hypotension and orthostatic hypotension can be increased when Secobarbital is combined with Hydrochlorothiazide.
Dantrolene	Dantrolene The risk or severity of adverse effects can be increased when Secobarbital is combined with Dantrolene.
Chlorzoxazone	Chlorzoxazone The risk or severity of adverse effects can be increased when Chlorzoxazone is combined with Secobarbital.
Carisoprodol	Carisoprodol The risk or severity of adverse effects can be increased when Carisoprodol is combined with Secobarbital.
Methocarbamol	Methocarbamol The risk or severity of adverse effects can be increased when Secobarbital is combined with Methocarbamol.
Pyridoxine	Pyridoxine The metabolism of Secobarbital can be increased when combined with Pyridoxine.
Folic Acid	Folic Acid Folic acid may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Disulfiram	Disulfiram The therapeutic efficacy of Secobarbital can be decreased when used in combination with Disulfiram.
Propranolol (Cardiovascular)	Propranolol (Cardiovascular) The serum concentration of Propranolol can be decreased when it is combined with Secobarbital.
Minoxidil	Minoxidil Secobarbital may increase the hypotensive activities of Minoxidil.
Nortriptyline	Nortriptyline The metabolism of Nortriptyline can be increased when combined with Secobarbital.
Spironolactone	Spironolactone Secobarbital may increase the hypotensive activities of Spironolactone.
Amphotericin B Injection	Amphotericin B Injection Secobarbital may increase the hypotensive activities of Amphotericin B.
Mercaptopurine	Mercaptopurine The serum concentration of Mercaptopurine can be decreased when it is combined with Secobarbital.
Phytonadione	Phytonadione Secobarbital may decrease the excretion rate of Phylloquinone which could result in a higher serum level.
Amikacin Injection	Amikacin Injection Amikacin may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Nadolol	Nadolol The serum concentration of Nadolol can be decreased when it is combined with Secobarbital.
Butorphanol Injection	Butorphanol Injection The risk or severity of adverse effects can be increased when Secobarbital is combined with Butorphanol.
Nalbuphine Injection	Nalbuphine Injection The risk or severity of adverse effects can be increased when Secobarbital is combined with Nalbuphine.
Allopurinol	Allopurinol Secobarbital may decrease the excretion rate of Allopurinol which could result in a higher serum level.
Trimethobenzamide	Trimethobenzamide The risk or severity of adverse effects can be increased when Secobarbital is combined with Trimethobenzamide.
Flavoxate	Flavoxate Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Flavoxate.
Papaverine	Papaverine Secobarbital may increase the hypotensive activities of Papaverine.
Fluorouracil Injection	Fluorouracil Injection The metabolism of Fluorouracil can be increased when combined with Secobarbital.
Colchicine	Colchicine Secobarbital may decrease the excretion rate of Colchicine which could result in a higher serum level.
Cefaclor	Cefaclor Cefaclor may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Cefadroxil	Cefadroxil Cefadroxil may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Cefazolin Injection	Cefazolin Injection Cefazolin may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Cephalexin	Cephalexin Cephalexin may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Cefoxitin Injection	Cefoxitin Injection Cefoxitin may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Dacarbazine	Dacarbazine The metabolism of Dacarbazine can be increased when combined with Secobarbital.
Acetazolamide	Acetazolamide The risk or severity of adverse effects can be increased when Secobarbital is combined with Acetazolamide.
Cefotaxime Injection	Cefotaxime Injection Cefotaxime may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Calcitonin Salmon Injection	Calcitonin Salmon Injection Salmon calcitonin may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Pyrantel	Pyrantel The risk or severity of adverse effects can be increased when Secobarbital is combined with Pyrantel.
Thiotepa Injection	Thiotepa Injection The metabolism of Secobarbital can be increased when combined with Thiotepa.
Vincristine Injection	Vincristine Injection The metabolism of Vincristine can be increased when combined with Secobarbital.
Captopril	Captopril Secobarbital may increase the hypotensive activities of Captopril.
Dipyridamole	Dipyridamole Secobarbital may increase the hypotensive activities of Dipyridamole.
Isoxsuprine	Isoxsuprine Secobarbital may increase the hypotensive activities of Isoxsuprine.
Vinblastine	Vinblastine The metabolism of Vinblastine can be increased when combined with Secobarbital.
Ethacrynic Acid	Ethacrynic Acid Secobarbital may increase the hypotensive activities of Etacrynic acid.
Colistimethate Injection	Colistimethate Injection Colistimethate may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Metoprolol	Metoprolol The serum concentration of Metoprolol can be decreased when it is combined with Secobarbital.
Hydroxyzine	Hydroxyzine Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Secobarbital.
Thiothixene	Thiothixene The risk or severity of adverse effects can be increased when Secobarbital is combined with Thiothixene.
Aspirin	Aspirin Acetylsalicylic acid may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Salsalate	Salsalate Salsalate may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Chlorambucil	Chlorambucil The therapeutic efficacy of Secobarbital can be decreased when used in combination with Chlorambucil.
Alprazolam	Alprazolam The risk or severity of adverse effects can be increased when Alprazolam is combined with Secobarbital.
Temazepam	Temazepam The risk or severity of adverse effects can be increased when Temazepam is combined with Secobarbital.
Triazolam	Triazolam The risk or severity of adverse effects can be increased when Secobarbital is combined with Triazolam.
Dicyclomine	Dicyclomine Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Dicyclomine.
Hyoscyamine	Hyoscyamine Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Hyoscyamine.
Propantheline	Propantheline Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Propantheline.
Trimethoprim	Trimethoprim Secobarbital may decrease the excretion rate of Trimethoprim which could result in a higher serum level.
Diltiazem	Diltiazem The metabolism of Diltiazem can be increased when combined with Secobarbital.
Nifedipine	Nifedipine The metabolism of Nifedipine can be increased when combined with Secobarbital.
Timolol	Timolol The serum concentration of Timolol can be decreased when it is combined with Secobarbital.
Verapamil	Verapamil The metabolism of Verapamil can be increased when combined with Secobarbital.
Atenolol	Atenolol The serum concentration of Atenolol can be decreased when it is combined with Secobarbital.
Pindolol	Pindolol The serum concentration of Pindolol can be decreased when it is combined with Secobarbital.
Cisplatin Injection	Cisplatin Injection Cisplatin may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Diflunisal	Diflunisal Diflunisal may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Piroxicam	Piroxicam The metabolism of Piroxicam can be increased when combined with Secobarbital.
Bumetanide	Bumetanide Secobarbital may increase the hypotensive activities of Bumetanide.
Etoposide	Etoposide The metabolism of Etoposide can be increased when combined with Secobarbital.
Glipizide	Glipizide Secobarbital may decrease the excretion rate of Glipizide which could result in a higher serum level.
Indapamide	Indapamide The risk or severity of hypotension and orthostatic hypotension can be increased when Secobarbital is combined with Indapamide.
Amoxicillin	Amoxicillin Secobarbital may decrease the excretion rate of Amoxicillin which could result in a higher serum level.
Oxacillin Injection	Oxacillin Injection Secobarbital may decrease the excretion rate of Oxacillin which could result in a higher serum level.
Pentoxifylline	Pentoxifylline The serum concentration of Pentoxifylline can be decreased when it is combined with Secobarbital.
Pentamidine Injection	Pentamidine Injection Pentamidine may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Ceftriaxone Injection	Ceftriaxone Injection Ceftriaxone may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Labetalol	Labetalol The serum concentration of Labetalol can be decreased when it is combined with Secobarbital.
Auranofin	Auranofin Secobarbital may decrease the excretion rate of Auranofin which could result in a higher serum level.
Leuprolide Injection	Leuprolide Injection Leuprolide may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Gemfibrozil	Gemfibrozil Secobarbital may decrease the excretion rate of Gemfibrozil which could result in a higher serum level.
Guanabenz	Guanabenz The metabolism of Guanabenz can be increased when combined with Secobarbital.
Dipivefrin Ophthalmic	Dipivefrin Ophthalmic Adefovir dipivoxil may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Ceftazidime Injection	Ceftazidime Injection Ceftazidime may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Ketoprofen	Ketoprofen Ketoprofen may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Cefotetan Injection	Cefotetan Injection Cefotetan may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Pimozide	Pimozide The metabolism of Pimozide can be increased when combined with Secobarbital.
Enalapril	Enalapril Secobarbital may increase the hypotensive activities of Enalapril.
Flurbiprofen	Flurbiprofen Flurbiprofen may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Amiodarone	Amiodarone The metabolism of Amiodarone can be increased when combined with Secobarbital.
Aztreonam Injection	Aztreonam Injection Aztreonam may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Buspirone	Buspirone Secobarbital may decrease the excretion rate of Buspirone which could result in a higher serum level.
Lovastatin	Lovastatin The metabolism of Lovastatin can be increased when combined with Secobarbital.
Ciprofloxacin	Ciprofloxacin Secobarbital may decrease the excretion rate of Ciprofloxacin which could result in a higher serum level.
Mesalamine	Mesalamine Mesalazine may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Diclofenac	Diclofenac The metabolism of Diclofenac can be increased when combined with Secobarbital.
Fluoxetine	Fluoxetine Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Nimodipine	Nimodipine The metabolism of Nimodipine can be increased when combined with Secobarbital.
Clozapine	Clozapine Clozapine may increase the central nervous system depressant (CNS depressant) activities of Secobarbital.
Estazolam	Estazolam The risk or severity of adverse effects can be increased when Secobarbital is combined with Estazolam.
Didanosine	Didanosine Secobarbital may decrease the excretion rate of Didanosine which could result in a higher serum level.
Pentostatin Injection	Pentostatin Injection Secobarbital may decrease the excretion rate of Pentostatin which could result in a higher serum level.
Benazepril	Benazepril Secobarbital may increase the hypotensive activities of Benazepril.
Etodolac	Etodolac Etodolac may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Felodipine	Felodipine Secobarbital may increase the hypotensive activities of Felodipine.
Fosinopril	Fosinopril Secobarbital may increase the hypotensive activities of Fosinopril.
Nabumetone	Nabumetone Nabumetone may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Quinapril	Quinapril Secobarbital may increase the hypotensive activities of Quinapril.
Ramipril	Ramipril Ramipril may increase the hypotensive activities of Secobarbital.
Simvastatin	Simvastatin The metabolism of Simvastatin can be increased when combined with Secobarbital.
Amlodipine	Amlodipine The metabolism of Amlodipine can be increased when combined with Secobarbital.
Teniposide Injection	Teniposide Injection The serum concentration of Teniposide can be decreased when it is combined with Secobarbital.
Lisinopril	Lisinopril Secobarbital may increase the hypotensive activities of Lisinopril.
Oxaprozin	Oxaprozin Oxaprozin may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Sotalol	Sotalol The serum concentration of Sotalol can be decreased when it is combined with Secobarbital.
Bisoprolol	Bisoprolol The serum concentration of Bisoprolol can be decreased when it is combined with Secobarbital.
Zolpidem	Zolpidem Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Doxazosin	Doxazosin Secobarbital may increase the hypotensive activities of Doxazosin.
Terazosin	Terazosin Secobarbital may increase the hypotensive activities of Terazosin.
Isradipine	Isradipine The metabolism of Isradipine can be increased when combined with Secobarbital.
Omeprazole	Omeprazole The metabolism of Omeprazole can be increased when combined with Secobarbital.
Cisapride	Cisapride The metabolism of Cisapride can be increased when combined with Secobarbital.
Gabapentin	Gabapentin The risk or severity of adverse effects can be increased when Secobarbital is combined with Gabapentin.
Fluvastatin	Fluvastatin The metabolism of Fluvastatin can be increased when combined with Secobarbital.
Venlafaxine	Venlafaxine The risk or severity of adverse effects can be increased when Venlafaxine is combined with Secobarbital.
Nizatidine	Nizatidine The therapeutic efficacy of Secobarbital can be decreased when used in combination with Nizatidine.
Famciclovir	Famciclovir The metabolism of Famciclovir can be increased when combined with Secobarbital.
Fluvoxamine	Fluvoxamine The risk or severity of adverse effects can be increased when Secobarbital is combined with Fluvoxamine.
Nefazodone	Nefazodone The risk or severity of adverse effects can be increased when Secobarbital is combined with Nefazodone.
Lamotrigine	Lamotrigine The serum concentration of Lamotrigine can be decreased when it is combined with Secobarbital.
Losartan	Losartan Secobarbital may increase the hypotensive activities of Losartan.
Valacyclovir	Valacyclovir Valaciclovir may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Tramadol	Tramadol The metabolism of Tramadol can be increased when combined with Secobarbital.
Vinorelbine Injection	Vinorelbine Injection The metabolism of Vinorelbine can be increased when combined with Secobarbital.
Carboplatin Injection	Carboplatin Injection Carboplatin may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Moexipril	Moexipril Secobarbital may increase the hypotensive activities of Moexipril.
Lansoprazole	Lansoprazole The metabolism of Lansoprazole can be increased when combined with Secobarbital.
Ifosfamide Injection	Ifosfamide Injection The metabolism of Ifosfamide can be increased when combined with Secobarbital.
Nicardipine	Nicardipine The metabolism of Nicardipine can be increased when combined with Secobarbital.
Bupropion	Bupropion The risk or severity of adverse effects can be increased when Secobarbital is combined with Bupropion.
Ticlopidine	Ticlopidine The metabolism of Secobarbital can be increased when combined with Ticlopidine.
Metformin	Metformin Metformin may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Nisoldipine	Nisoldipine Secobarbital may increase the hypotensive activities of Nisoldipine.
Lamivudine	Lamivudine Secobarbital may decrease the excretion rate of Lamivudine which could result in a higher serum level.
Riluzole	Riluzole The risk or severity of adverse effects can be increased when Secobarbital is combined with Riluzole.
Amifostine Injection	Amifostine Injection Secobarbital may increase the hypotensive activities of Amifostine.
Acarbose	Acarbose Acarbose may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Anastrozole	Anastrozole The metabolism of Anastrozole can be increased when combined with Secobarbital.
Gemcitabine Injection	Gemcitabine Injection Secobarbital may decrease the excretion rate of Gemcitabine which could result in a higher serum level.
Docetaxel Injection	Docetaxel Injection The metabolism of Docetaxel can be increased when combined with Secobarbital.
Cidofovir Injection	Cidofovir Injection Cidofovir may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Meropenem Injection	Meropenem Injection Secobarbital may decrease the excretion rate of Meropenem which could result in a higher serum level.
Clomipramine	Clomipramine The metabolism of Clomipramine can be increased when combined with Secobarbital.
Zafirlukast	Zafirlukast The metabolism of Zafirlukast can be increased when combined with Secobarbital.
Fosfomycin	Fosfomycin Secobarbital may decrease the excretion rate of Fosfomycin which could result in a higher serum level.
Mirtazapine	Mirtazapine Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Trandolapril	Trandolapril Secobarbital may increase the hypotensive activities of Trandolapril.
Topiramate	Topiramate The risk or severity of adverse effects can be increased when Topiramate is combined with Secobarbital.
Zileuton	Zileuton The metabolism of Zileuton can be increased when combined with Secobarbital.
Valsartan	Valsartan Secobarbital may increase the hypotensive activities of Valsartan.
Pramipexole	Pramipexole Secobarbital may increase the sedative activities of Pramipexole.
Donepezil	Donepezil The therapeutic efficacy of Secobarbital can be decreased when used in combination with Donepezil.
Azithromycin	Azithromycin The metabolism of Azithromycin can be increased when combined with Secobarbital.
Loratadine	Loratadine Secobarbital may increase the anticholinergic activities of Loratadine.
Carvedilol	Carvedilol The serum concentration of Carvedilol can be decreased when it is combined with Secobarbital.
Nilutamide	Nilutamide Secobarbital may decrease the excretion rate of Nilutamide which could result in a higher serum level.
Flutamide	Flutamide The metabolism of Flutamide can be increased when combined with Secobarbital.
Selegiline	Selegiline The metabolism of Selegiline can be increased when combined with Secobarbital.
Bicalutamide	Bicalutamide The metabolism of Bicalutamide can be increased when combined with Secobarbital.
Sertraline	Sertraline The risk or severity of adverse effects can be increased when Secobarbital is combined with Sertraline.
Propafenone	Propafenone The serum concentration of Propafenone can be decreased when it is combined with Secobarbital.
Irbesartan	Irbesartan The metabolism of Irbesartan can be increased when combined with Secobarbital.
Tamsulosin	Tamsulosin Secobarbital may increase the hypotensive activities of Tamsulosin.
Ropinirole	Ropinirole The metabolism of Ropinirole can be increased when combined with Secobarbital.
Quetiapine	Quetiapine Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Quetiapine.
Cefepime Injection	Cefepime Injection Cefepime may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Cefprozil	Cefprozil Cefprozil may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Cefpodoxime	Cefpodoxime Cefpodoxime may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Cetirizine	Cetirizine The risk or severity of adverse effects can be increased when Cetirizine is combined with Secobarbital.
Paroxetine	Paroxetine The risk or severity of adverse effects can be increased when Secobarbital is combined with Paroxetine.
Tolcapone	Tolcapone The risk or severity of adverse effects can be increased when Tolcapone is combined with Secobarbital.
Citalopram	Citalopram The risk or severity of adverse effects can be increased when Secobarbital is combined with Citalopram.
Capecitabine	Capecitabine The metabolism of Capecitabine can be increased when combined with Secobarbital.
Efavirenz	Efavirenz The risk or severity of adverse effects can be increased when Secobarbital is combined with Efavirenz.
Abacavir	Abacavir Secobarbital may decrease the excretion rate of Abacavir which could result in a higher serum level.
Pioglitazone	Pioglitazone The metabolism of Pioglitazone can be increased when combined with Secobarbital.
Celecoxib	Celecoxib The metabolism of Celecoxib can be increased when combined with Secobarbital.
Rosiglitazone	Rosiglitazone The metabolism of Rosiglitazone can be increased when combined with Secobarbital.
Tolterodine	Tolterodine Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Tolterodine.
Thalidomide	Thalidomide Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Oseltamivir	Oseltamivir Oseltamivir may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Balsalazide	Balsalazide Balsalazide may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Nateglinide	Nateglinide Secobarbital may decrease the excretion rate of Nateglinide which could result in a higher serum level.
Galantamine	Galantamine The therapeutic efficacy of Secobarbital can be decreased when used in combination with Galantamine.
Levetiracetam	Levetiracetam The risk or severity of adverse effects can be increased when Secobarbital is combined with Levetiracetam.
Rabeprazole	Rabeprazole Secobarbital may decrease the excretion rate of Rabeprazole which could result in a higher serum level.
Terbinafine	Terbinafine The metabolism of Terbinafine can be increased when combined with Secobarbital.