Good Sense Nasal Four Phenylephrine hydrochloride 1 g/100mL Spray, 1 bottle
by L. Perrigo Company · 1 BOTTLE in 1 CARTON (0113-0648-10) / 29.6 mL in 1 BOTTLE
NDC 00113-0648-10
🏷️ FDA NDC (as labeled)
0113-0648-10
billing pads the labeler segment with a zero
OTC
On market
Non-controlled
🗂️ Data synced Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →
🆔 Identity & classification
FDA NDC (as labeled)
0113-0648-10
Product NDC
0113-0648
11-digit billing NDC
00113064810
NCPDP billing unit
ML — per mL (volume)
RxCUI
1087043
UNII
04JA59TNSJ
Application #
M012
SPL Set ID
930469c1-384c-4440-b3e6-9dcd674871c4
Established class (EPC)
alpha-1 Adrenergic Agonist
Mechanism of action
Adrenergic alpha1-Agonists
DEA schedule
Non-controlled
Marketing category
OTC MONOGRAPH DRUG
Marketing status
On market
FDA listing status
Listed (active directory)
Marketing start
2002-08-09
Route
NASAL
Dosage form
SPRAY
Substance
PHENYLEPHRINE HYDROCHLORIDE
GPI-14
42102050102015
GPI class
Nasal Four
GCN Seq No
008062
GCN
34124
HICL code
002087
Ingredient (HICL)
Phenylephrine Hcl
HIC1 code
Q
Therapeutic class — broad (HIC1)
Ear/Eye/Nose/Rectum/Topical/Vagina/Other
HIC2 code
Q7
Therapeutic class — intermediate (HIC2)
Nasal Preparations
HIC3 code
Q7D
Therapeutic class — specific (HIC3)
Nose Preparations, Vasoconstrictors(Otc)
AHFS code
12:12.04.00
AHFS class
Alpha-Adrenergic Agonists (12:12)
FDB label name
GS NASAL FOUR 1% NASAL SPRAY
FDB brand name
Nasal Four
Legend status
O — Over-the-counter (OTC) drug or device
Why two NDCs?
The FDA registers this code as 0113-0648-10 — a 4-4-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the labeler segment → 00113-0648-10. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.
🏷️ RxNorm drug class
This medicine belongs to the alpha-1 Adrenergic Agonist class.
Pharmacologic class
alpha-1 Adrenergic Agonist
Drug family (ATC)
Sympathomimetics excl. antiglaucoma preparations, Adrenergic and dopaminergic agents, Other agents for treatment of hemorrhoids and anal fissures for topical use
How it works
Adrenergic alpha1-Agonists
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.
🏭 Manufacturer & labeler
LabelerL. Perrigo Company
FDA applicationM012 (OTC MONOGRAPH DRUG)
Labeler code00113
First marketedAug 2002
Product typeHuman Otc Drug
Portfolio228 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.
🩺 Clinical
Label name GS NASAL FOUR 1% NASAL SPRAY Ingredient Phenylephrine Hcl
📗 Our plain-language guide HelloPharmacist
- Yes, it's the same active ingredient, but used in very different ways depending on the form. The nasal spray delivers a tiny amount directly to the nasal lining to temporarily shri...
- I see phenylephrine in nasal sprays at the pharmacy AND as an IV drug in the hospital — is it really the same medication?
- You should check with your doctor first. Phenylephrine constricts blood vessels, which can raise blood pressure and put extra strain on the heart — even from a nasal spray. If you...
- Can I use the nasal spray if I have high blood pressure or heart disease?
Patient education
Supplement & herbal interactions
Some supplements/herbs that may interact with Phenylephrine Hydrochloride — tap one for details:
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.
💬 Questions about Phenylephrine hydrochloride?
Ask a pharmacist →
Ask a licensed pharmacist directly — free, answered by our team.
🧪 Inactive Ingredients / Excipients
Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.
💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.
-
UNII F5UM2KM3W7
Benzalkonium chloride is a chemical compound that works as a preservative and antimicrobial agent in medications. It prevents bacterial and fungal growth in liquid formulations to keep the product safe during storage and use.
-
UNII LKG8494WBH
Benzyl alcohol is a clear liquid used as a preservative and solvent in medicines. It helps prevent bacterial and fungal growth and dissolves other ingredients to create uniform liquid formulations.
-
UNII R57ZHV85D4
Boric acid is a weak acid derived from boron. In medicines, it typically serves as a buffer to help maintain the product's pH level and may act as a preservative in certain formulations.
-
UNII 91MBZ8H3QO
Sodium borate is an inorganic salt compound used in medicines as a buffer to help maintain a stable pH level, and sometimes as a mild preservative or cleansing agent in topical formulations.
-
UNII 059QF0KO0R
Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.
5 inactive ingredients listed in the exact product block matched to this NDC.
The official label also statesbenzalkonium chloride solution, benzyl alcohol, boric acid, purified water, sodium borate
Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.
Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed —
ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.Inactive ingredient FAQ
Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.
💲 Pricing
A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.
| Price system | Per mL | Per package |
|---|---|---|
| Retail pharmacies payNADAC · weekly | $0.067 | $1.99 / 29.6 ml |
| Medicaid paysCMS SDUD · 12 mo | No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data. | |
| Medicare drug plans payPart D · quarterly | No Part D plan price is available for this NDC in our data. | |
NADAC price history (per mL) — tap or hover for the price & month
▼ Down 11% over the last 19 months.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.
🔁 Therapeutic equivalents
| Product | Labeler | Pack | NADAC/unit | TE | Status | Price vs. this |
|---|---|---|---|---|---|---|
| Good Sense Nasal Four 1 g/100mLthis 00113-0648-10 | L. | 1 bottle | $0.067 | — | Availability likely | — |
| Extra Strength Sinus Relief Nasal Decongestant 1 g/100mL 70000-0132-01 | CARDINAL | 1 bottle | $0.070 | — | Availability likely | +5% |
| Quality Choice 1 g/100mL 83324-0215-01 | CHAIN | 1 bottle | $0.070 | — | Availability likely | +5% |
| good neighbor pharmacy nasal four 1 g/100mL 46122-0689-03 | Amerisource | 1 bottle | $0.084 | — | Availability likely | +25% |
| 4 Way Fast Acting 10 mg/mL 00067-2086-01 | Haleon | 1 bottle | — | — | FDA listed | — |
| Neo-Synephrine Maximum 1 g/100mL 00225-0810-47 | BF | 15 ml | — | — | FDA listed | — |
| Neo-Synephrine Severe 1 g/100mL 00225-0811-47 | BF | 15 ml | — | — | FDA listed | — |
| nasal 1 g/100mL 00363-0717-10 | Walgreen | 1 bottle | — | — | FDA listed | — |
| Better Living 1 g/100mL 21130-0728-30 | BETTER | 1 bottle | — | — | FDA listed | — |
| nasal 1 g/100mL 30142-0539-10 | Kroger | 1 bottle | — | — | FDA listed | — |
| Topcare Nasal Four 1 g/100mL 36800-0648-10 | Topco | 1 bottle | — | — | FDA listed | — |
| heb nasal 1 g/100mL 37808-0728-30 | H | 1 bottle | — | — | FDA listed | — |
| equaline nasal 1 g/100mL 41163-0648-10 | United | 1 bottle | — | — | FDA listed | — |
| Publix 1 g/100mL 41415-0728-30 | PUBLIX | 1 bottle | — | — | FDA listed | — |
| CareOne Fast Acting Nasal 1 g/100mL 41520-0729-10 | American | 1 bottle | — | — | FDA listed | — |
| Nasal Four 1 g/100mL 42507-0648-10 | HyVee | 1 bottle | — | — | FDA listed | — |
| Equate Nasal 1 g/100mL 49035-0648-10 | Wal-Mart | 1 bottle | — | — | FDA listed | — |
| No Drip Nasal 10 mg/mL 51316-0648-10 | CVS | 1 bottle | — | — | FDA listed | — |
| dg health nasal four 1 g/100mL 55910-0802-10 | Dolgencorp, | 1 bottle | — | — | FDA listed | — |
| Dollar General 1 g/100mL 55910-0827-30 | DOLGENCORP, | 1 bottle | — | — | FDA listed | — |
| CVS Health Four Actions Nasal Decongestant 10 mg/mL 59779-0838-30 | CVS | 1 bottle | — | — | FDA listed | — |
| Quality Choice 1 g/100mL 63868-0697-30 | CHAIN | 1 bottle | — | — | FDA listed | — |
| Extra Strength Nasal 1 g/100mL 69842-0443-30 | CVS | 1 bottle | — | — | FDA listed | — |
| Nasal 1 g/100mL 69842-0648-10 | CVS | 1 bottle | — | — | FDA listed | — |
| basic care nasal 1 g/100mL 72288-0648-10 | Amazon.com | 1 bottle | — | — | FDA listed | — |
| Nasal 1 g/100mL 79481-0101-00 | Meijer, | 1 bottle | — | — | FDA listed | — |
| Equate Nasal 10 mg/mL 79903-0276-01 | WALMART | 1 bottle | — | — | FDA listed | — |
| Ephrine Nose Drops 1 g/100mL 00363-2023-10 | Walgreens | 1 bottle | — | — | FDA listed | — |
| Nasal 1 g/100mL 72288-0742-10 | Amazon.com | 1 bottle | — | — | FDA listed | — |
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.
⏳ Availability & generic status
🏛️
2002
On the market since
Aug 2002
📍
2026
Currently FDA-listed
24 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found
We did not find an FDA-approved generic match for this exact strength, form and route.
Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.
🔬 Reported adverse events (FAERS)
Read carefully: FAERS reports are voluntary and unverified. Counts are not incidence, do not establish causation, are subject to reporting bias, and cannot be used to compare one drug to another. Shown for signal context only. Reports for Phenylephrine hydrochloride — the ingredient across all brands.
Top reported reactions
Reporter sex
Male · 31%
Female · 69%
Unknown · 0%
Serious outcomes
Reports over time (by year) — tap or hover for the count & year
Most recent year is provisional (FAERS lags ~3 months).
Where does this data come from?
Adverse-event reports from the FDA Adverse Event Reporting System (FAERS) via openFDA. FAERS reports are voluntary and unverified — counts are not incidence and don’t establish causation.
📦 Packaging — all sizes for this product
| Package NDC | Description | Marketing start | Status |
|---|---|---|---|
| 00113-0648-10 You're viewing this | 1 BOTTLE in 1 CARTON (0113-0648-10) / 29.6 mL in 1 BOTTLE | 2002-08-09 | Active |
📄 FDA label — Drug Facts FDA SPL
The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage
⏱️ Dosage and Administration
⚠️ Warnings
📦 Storage and Handling
🧪 Active Ingredient
🧪 Inactive Ingredients
🎯 Purpose
🎯 Indications and Usage ▾
Uses • temporarily relieves nasal congestion due to: • common cold • hay fever • upper respiratory allergies
⏱️ Dosage and Administration ▾
Directions • adults and children 12 years and over: 2 or 3 sprays in each nostril not more often than every 4 hours • children under 12 years: ask a doctor • Use instructions: with head in a normal, upright position, put atomizer tip into nostril. Squeeze bottle with firm, quick pressure while inhaling. Wipe nozzle clean after each use.
⚠️ Warnings ▾
Warnings Ask a doctor before use if you have • heart disease • diabetes • thyroid disease • high blood pressure • trouble urinating due to an enlarged prostate gland When using this product • do not use more than directed • do not use for more than 3 days. Frequent or prolonged use may cause nasal congestion to come back or get worse. • use only as directed • temporary discomfort such as burning, stinging, sneezing or an increase in nasal discharge may occur • use of this container by more than one person may spread infection Stop use and ask a doctor if symptoms persist If pregnant or breast-feeding, ask a health professional before use.
Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away. (1-800-222-1222)
📦 Storage and Handling ▾
Other information • store at 20°-25°C (68°-77°F)
🧪 Active Ingredient ▾
Active ingredient Phenylephrine hydrochloride 1%
🧪 Inactive Ingredients ▾
Inactive ingredients benzalkonium chloride solution, benzyl alcohol, boric acid, purified water, sodium borate
🎯 Purpose ▾
Purpose Nasal decongestant
No label section mentions that — try another word, or open the full label on DailyMed below.
Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA.
Prefer the government’s original formatting? View this label on DailyMed ↗
For educational and professional reference only — not medical advice. Pricing reflects published
NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.