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Motion Sickness Relief Meclizine HCl 25 mg Tablet, Chewable

by Walgreen Company · 2 BLISTER PACK in 1 CARTON (0363-0404-21) / 8 TABLET, CHEWABLE in 1 BLISTER PACK
NDC 00363-0404-21
🏷️ FDA NDC (as labeled) 0363-0404-21 billing pads the labeler segment with a zero
OTC Discontinued Non-controlled ⚠ Discontinued by firm
🗂️ Data synced Mar 13, 2024 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

⚠️
Excluded from the active FDA NDC Directory. The labeler reported this product as discontinued, so it is excluded from the active NDC Directory. The listing was last certified through Mar 2026. A label may still appear on DailyMed, but the NDC is no longer in the current FDA NDC Directory. Search the FDA NDC Directory ↗

🆔 Identity & classification

FDA NDC (as labeled) 0363-0404-21
Product NDC 0363-0404
11-digit billing NDC 00363040421
NCPDP billing unit EA — each (per item)
Application # M009
Physiologic effect Antiemetic [EPC], Emesis Suppression
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status Discontinued
FDA listing status Discontinued by firm (certified through Mar 2026)
Route ORAL
Dosage form TABLET, CHEWABLE
Substance MECLIZINE HYDROCHLORIDE
GCN Seq No 004736
GCN 18312
HICL code 001975
Ingredient (HICL) Meclizine Hcl
HIC1 code H
Therapeutic class — broad (HIC1) Nervous System (Except Autonomic)
HIC2 code H6
Therapeutic class — intermediate (HIC2) Drugs Acting Principally On The Midbrain
HIC3 code H6J
Therapeutic class — specific (HIC3) Antiemetic/Antivertigo Agents
AHFS code 04:04.16.00
AHFS class Piperazine Derivatives
FDB label name MOTION SICKNESS 25 MG CHEW TAB
FDB brand name Motion Sickness Relief
Legend status O — Over-the-counter (OTC) drug or device
Why two NDCs? The FDA registers this code as 0363-0404-21 — a 4-4-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the labeler segment → 00363-0404-21. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

🏭 Manufacturer & labeler

LabelerWalgreen Company
FDA applicationM009 (OTC MONOGRAPH DRUG)
Labeler code00363
Product typeHuman Otc Drug
Portfolio468 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

🩺 Clinical

Label name MOTION SICKNESS 25 MG CHEW TAB Ingredient Meclizine Hcl
📖 What it is MedlinePlus · NLM

Meclizine is used to prevent and treat nausea, vomiting, and dizziness caused by motion sickness. It is most effective if taken before symptoms appear.

Read the full MedlinePlus article ↗
📗 Our plain-language guide HelloPharmacist
  • Meclizine is mainly used to prevent and treat the nausea, vomiting, and dizziness that comes with motion sickness — whether you're on a boat, in a car, or on a plane. It's also use...
  • For the best chance of preventing motion sickness, take meclizine about one hour before you start traveling. After that first dose, you can take it once every 24 hours as needed fo...
  • Yes, drowsiness is the most common side effect — it's actually worth planning around. Avoid driving or operating heavy machinery until you know how it affects you. And definitely s...
  • This one requires a conversation with your doctor. Human studies haven't clearly linked meclizine to birth defects, but animal studies did show fetal harm at doses similar to what...
📖 Read our full Meclizine guide →

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

🧪 Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

Loading inactive ingredients from the official FDA label in the background. No external source is being called by this page request.
Where does this data come from?
Source: official FDA Structured Product Labeling (SPL) via DailyMed and the openFDA label index. Structured IACT rows and label-wide narrative are kept separate; availability and product-level specificity depend on the submitted label.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

💲 Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer eachPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

🔁 Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Meclizine Hydrochloride 25 mg 00536-1299-01 Rugby 100 tablets $0.033 — Availability likely —
Meclizine HCl 25 mg 16571-0824-01 Rising 100 tablets $0.033 — Availability likely —
Motion Sickness Relief 25 mg 46122-0774-51 Amerisource 8 tablets $0.033 — Availability likely —
Motion-Time Chewable 25 mg/251 49483-0333-01 Time-Cap 100 tablets $0.033 — Availability likely —
Meclizine HCl 25 mg 68001-0529-00 BluePoint 100 tablets $0.033 — Availability likely —
Motion Sickness 25 mg 70677-1290-01 Strategic 100 tablets $0.033 — Availability likely —
Travel ease 25 mg 83324-0027-16 Chain 8 tablets $0.033 — Availability likely —
Motion Sickness Relief 25 mg 00363-4040-21 Walgreen 8 tablets — — FDA listed —
Meclizine Hydrochloride 25 mg 00363-5172-07 Walgreen 12 tablets — — FDA listed —
Motion Sickness Relief 25 mg 11822-4040-01 Rite 8 tablets — — FDA listed —
Meclizine 25 mg 16103-0387-08 Pharbest 100 tablets — — FDA listed —
Meclizine Hydrochloride 25 mg 16571-0663-01 Rising 100 tablets — — FDA listed —
Meclizine HCL 25 mg 17714-0115-01 Advance 100 tablets — — FDA listed —
Meclizine 25 mg 37835-0202-01 Bi-Mart 100 tablets — — FDA listed —
Meclizine 25 mg 43063-0804-01 PD-Rx 100 tablets — — FDA listed —
Meclizine Hydrochloride 25 mg 50090-5496-00 A-S 30 tablets — — FDA listed —
Meclizine Hydrochloride 25 mg 50090-5952-00 A-S 30 tablets — — FDA listed —
Motion Sickness Relief 25 mg 51013-0322-54 PuraCap 2 tablets — — FDA listed —
Motion Sickness Relief 25 mg 51316-0404-21 CVS 8 tablets — — FDA listed —
Motion Sickness 25 mg 51316-0441-21 CVS 8 tablets — — FDA listed —
Meclizine HCL 25 mg 54738-0025-01 Richmond 100 tablets — — FDA listed —
Dramamine 25 mg 63029-0906-12 Medtech 12 tablets — — FDA listed —
Dramamine 25 mg 63029-0913-12 Medtech 12 tablets — — FDA listed —
Dramamine 25 mg 63029-0914-12 Medtech 12 tablets — — FDA listed —
Bonine 25 mg 65197-0275-02 WellSpring 2 tablets — — FDA listed —
Bonine 25 mg 65197-0296-08 WellSpring 8 tablets — — FDA listed —
Bonine 25 mg 65197-0297-08 WellSpring 8 tablets — — FDA listed —
Meclizine Hydrochloride 25 mg 68071-2574-02 NuCare 20 tablets — — FDA listed —
Meclizine HCL 25 mg 68788-7982-01 Preferred 10 tablets — — FDA listed —
Meclizine HCl 25 mg 68788-8529-01 Preferred 10 tablets — — FDA listed —
Meclizine HCL 25 mg 69618-0028-01 Reliable 100 tablets — — FDA listed —
Motion Sickness Relief 25 mg 69842-0395-54 CVS 2 tablets — — FDA listed —
Meclizine HCL 25 mg 71205-0606-30 Proficient 30 tablets — — FDA listed —
Meclizine 25 mg 71335-1215-00 Bryant 120 tablets — — FDA listed —
Meclizine HCL 25 mg 71335-1607-00 Bryant 120 tablets — — FDA listed —
Meclizine Hydrochloride 25 mg 71335-2177-00 Bryant 120 tablets — — FDA listed —
Meclizine HCl 25 mg 71335-9751-00 Bryant 120 tablets — — FDA listed —
Meclizine HCL 25 mg 71610-0528-30 Aphena 30 tablets — — FDA listed —
Meclizine Hydrochloride 25 mg 71610-0836-30 Aphena 30 tablets — — FDA listed —
Meclizine Hydrochloride 25 mg 72789-0250-12 PD-Rx 12 tablets — — FDA listed —
Meclizine 25 mg 80513-0421-02 Advanced 200 tablets — — FDA listed —
Motion Sickness Relief 25 mgthis 00363-0404-21 Walgreen 8 tablets — — Discontinued —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

⏳ Availability & generic status

📍
2026
Currently FDA-listed
listed with the FDA
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

📊 Medicare Part D spend CMS · PART D · 2026 (Q1)

Medicare Part D (outpatient prescription) spending for Meclizine HCl (matched by generic name) — the program that covers self-administered drugs. 8 manufacturers.
⚠️ Drug-level data: CMS publishes Part D spending by drug, not by NDC — these figures combine every manufacturer, strength and package size sold under the name Meclizine HCl. That’s a different level of aggregation than the Medicaid card above, which is specific to this exact 11-digit NDC (pack size included), so the two aren’t directly comparable.
Period
Total Part D spend
$6.73M
Claims incl. refills
748.9K
Beneficiaries
532.6K
Spend / beneficiary
$12.64
Spend / claim
$8.99
Trend by period
💵 About the dollar figures: spending is what Part D plans paid before confidential manufacturer rebates, so the program’s real net cost is lower. A blank patient count means fewer than 11 people — CMS hides counts that small to protect privacy. Source: CMS Medicare Quarterly Part D Spending by Drug (data.cms.gov), updated quarterly.

🔬 Reported adverse events (FAERS)

Read carefully: FAERS reports are voluntary and unverified. Counts are not incidence, do not establish causation, are subject to reporting bias, and cannot be used to compare one drug to another. Shown for signal context only. Reports for Motion Sickness Relief (this brand).

Top reported reactions

Nausea1,099
Fatigue939
Febrile Neutropenia814
Dizziness762
Headache677
Vomiting644
Diarrhoea606

Age at onset

Neonate41
Infant56
Child195
Adolescent100
Adult1,209
Elderly891

Reporter sex

10,118 reports
Male · 33%
Female · 66%
Unknown · 0%

Serious outcomes

Hospitalization4,198
Life-threatening882
Death861
Disabling250
Reports over time (by year) — tap or hover for the count & year
2019 2021 2023 2026 1,172 0
Most recent year is provisional (FAERS lags ~3 months).
Where does this data come from?
Adverse-event reports from the FDA Adverse Event Reporting System (FAERS) via openFDA. FAERS reports are voluntary and unverified — counts are not incidence and don’t establish causation.

📦 Packaging — all sizes for this product

Package NDCDescription Marketing startStatus
00363-0404-21 You're viewing this 2 BLISTER PACK in 1 CARTON (0363-0404-21) / 8 TABLET, CHEWABLE in 1 BLISTER PACK 2002-05-29 Discontinued by firm

🧭 About this NDC listing & data coverage

Over-the-counter (OTC) product No longer marketed (per FDA listing data)
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) — Not published for this NDC No structured label is linked to this listing in DailyMed/openFDA.
Package photos — Not published for this NDC No photo available yet for this listing.
Inactive ingredients (structured) — Not published for this NDC The labeler did not submit a structured excipient list, or no SPL is available.
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Why is there no full label on this page?
No structured FDA label (SPL) is currently linked to this NDC in DailyMed/openFDA. That can happen with older listings, certain OTC and repackaged products, and recently updated listings whose label has not yet propagated. The listing itself is still valid — this page shows everything the public feeds provide for this package.
What does the discontinued status mean for this NDC?
The labeler reported a marketing end date (or the listing was delisted), so this specific package is no longer actively marketed. Remaining stock may still be dispensed for a time, and the NDC stays valid for historical records and claims — but data feeds (pricing, labeling) typically stop updating for it. Other package sizes or other manufacturers' versions of the same medication may still be marketed — see the equivalents section where available.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The FDA registers it as 0363-0404-21, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 00363-0404-21, written without dashes as 00363040421. The Identity section at the top of this page lists every form of this code.
What do the three segments of this NDC mean?
In 00363-0404-21, the first segment (00363) is the labeler code FDA assigned to Walgreen Company; the middle segment (0404) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (21) identifies this exact package size and type. Together they name one specific package of one specific product.
Who lists this product with the FDA?
Walgreen Company is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.

📄 FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
📄 FDA label
📄 FDA label 19 words ▾

No FDA label is on file for this product yet. Labels load from openFDA / DailyMed and refresh weekly.

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA.
← 00363-0401-34 · Walgreen 00363-0406-15 · WALGREEN →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.