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diphenhydramine hcl and zinc acetate Diphenhydramine Hydrochloride, 2 g/100g; .1 g/100g Cream — NDC 45802-358-03 (Billing 45802-0358-03)

by Padagis Israel Pharmaceuticals Ltd · 1 TUBE in 1 CARTON / 28 g in 1 TUBE

This is a package of diphenhydramine hcl and zinc acetate Diphenhydramine Hydrochloride, 2 g/100g; .1 g/100g Cream from Padagis Israel Pharmaceuticals Ltd, marketed since Dec 2005 and currently FDA-listed; retail pharmacies pay about $0.0575 per g (NADAC). It is this product's only package size.

NDC 45802-0358-03
🏷️ FDA NDC (as labeled) 45802-358-03 billing pads the product segment with a zero
OTC On market Non-controlled ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 1, 2026 · this listing last changed Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

NDC database record

One package, one record: these facts belong to NDC 45802-358-03 alone.

Record
FDA NDC Directory package listing · Human OTC drug
Code segments
45802 labeler · 358 product · 03 package
Package marketed since
Dec 5, 2005
Sample package
No — commercial package
Listing certified through
Dec 31, 2027
Barcode (UPC-A, from the NDC)
3 4580235803 5
Medicaid fills, this package
457 prescriptions in the last four reported quarters
FDA record last changed
Jul 24, 2026

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 45802-358-03
Product NDC 45802-358
11-digit billing NDC 45802035803
NCPDP billing unit GM — per gram (weight)
RxCUI 1087026
UNII TC2D6JAD40, FM5526K07A
Application # M017
SPL Set ID 6d7a7615-9ae7-4c55-8a84-dba746f535d7
Established class (EPC) Copper Absorption Inhibitor; Histamine-1 Receptor Antagonist
Mechanism of action Histamine H1 Receptor Antagonists
Physiologic effect Decreased Copper Ion Absorption
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2005-12-05
Route TOPICAL
Dosage form CREAM
Substance DIPHENHYDRAMINE HYDROCHLORIDE; ZINC ACETATE

Drug-database identifiers Medi-Span GPI and First Databank GCN / HICL / AHFS classification

GPI-14 90209902083735
GPI class diphenhydrAMINE-Zinc Acetate
GCN Seq No 024972
GCN 67334
HICL code 009759
Ingredient (HICL) Diphenhydramine Hcl/Zinc Acet
HIC1 code L
Therapeutic class — broad (HIC1) Skin/Subcutaneous Tissue
HIC2 code L3
Therapeutic class — intermediate (HIC2) Protectives
HIC3 code L3P
Therapeutic class — specific (HIC3) Antipruritics,Topical
AHFS code 84:08.00.00
AHFS class Antipruritics And Local Anesthetics
FDB label name ITCH RELIEF 2%-0.1% CREAM
FDB brand name Itch Relief
Legend status O — Over-the-counter (OTC) drug or device
Quick answers
  • GSN (GCN sequence number): 024972
  • GCN: 67334
  • GPI-14 (Medi-Span): 90209902083735
  • HICL (First Databank): 009759
  • AHFS class code: 84:08.00.00
  • RxCUI (RxNorm): 1087026
Why two NDCs? The FDA registers this code as 45802-358-03 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 45802-0358-03. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

RxNorm drug class

This medicine belongs to the Histamine-1 Receptor Antagonist class.

Pharmacologic class Histamine-1 Receptor Antagonist
Drug family (ATC) Propionic acid derivatives, Antihistamines for topical use, Aminoalkyl ethers
How it works Histamine H1 Receptor Antagonists
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

Clinical

Label name ITCH RELIEF 2%-0.1% CREAM Ingredient Diphenhydramine Hcl/Zinc Acet
📖 About the active ingredient: Diphenhydramine Hydrochloride; Zinc Acetate MedlinePlus · NLM
General information about the ingredient itself — the description of this specific product follows below.

Diphenhydramine is used to treat allergy and cold symptoms: sneezing runny nose red, itchy, watery eyes itching of the nose or throat Diphenhydramine is also used to treat insomnia (difficulty falling asleep or staying asleep) in adults, but should not be used to make a child sleepy. Diphenhydramine is in a class of medications called antihistamines. It works by blocking the action of histamine, a substance in the body that causes allergic symptoms. Diphenhydramine is also available in combination with other medications. This monograph only includes information about the use of diphenh...

Read the full MedlinePlus article ↗
🧪 What is this product?

This is an over-the-counter topical cream containing diphenhydramine hydrochloride and zinc acetate. Diphenhydramine is an antihistamine typically used in topical products to help reduce itching and minor skin irritation. Zinc acetate is commonly included in skin creams for its astringent and skin-soothing properties. The product is applied directly to the skin as part of the OTC monograph category for topical antacne and skin-protectant preparations.

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
1
Nutrient depletion considerations

Diphenhydramine Hydrochloride, Naproxen Sodium may be associated with lower levels of 1 nutrient — worth a chat with your pharmacist, not a cause for alarm.

🧪 Full Diphenhydramine Hydrochloride, Naproxen Sodium nutrient depletion report →
An association is not a deficiency. Educational only — don't start or stop anything without professional guidance.
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer gPer package
Retail pharmacies payNADAC · weekly $0.058 $1.61 / 28 g
Medicaid paysCMS SDUD · 12 mo $0.2590 $7.25 / 28 g
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
NADAC price history (per g) — tap or hover for the price & month
Jan 2022 Aug 2022 Jan 2026 Sep 2026 $0.075 $0.048
▼ Down 7% over the last 24 months.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Marketing startMarketing endStatus
45802-0358-03 You're viewing this Main listing 1 TUBE in 1 CARTON / 28 g in 1 TUBE 2005-12-05 — Active

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
good sense itch relief 2 g/100g; .1 g/100g 00113-0622-64 L. 1 tube $0.058 — Availability likely —
Banophen 2 g/100g; .1 g/100g 00904-5354-31 Major 1 tube $0.058 — Availability likely —
diphenhydramine hcl and zinc acetate 2 g/100g; .1 g/100gthis 45802-0358-03 Padagis 1 tube $0.058 — Availability likely —
GNP Extra Strength Anti-Itch Cream .1 g/100g; 2 g/100g 46122-0804-36 Amerisource 1 tube $0.058 — Availability likely —
leader anti itch 2 g/100g; .1 g/100g 70000-0388-01 Cardinal 1 tube $0.058 — Availability likely —
foster and thrive anti itch cream 2 g/100g; .1 g/100g 70677-1289-01 Strategic 1 tube $0.058 — Availability likely —
Anti-Itch 20 mg/g; 1 mg/g 24385-0210-03 Amerisource 1 tube $0.130 — Discontinued +125%
Diphenhydramine Hydrochloride and Zinc Acetate 20 mg/g; 1 mg/g 70677-1213-01 STRATEGIC 1 tube $0.130 — FDA listed +125%
Walgreens Anti Itch Cream 20 mg/g; 1 mg/g 00363-2315-28 Walgreens 1 tube — — FDA listed —
Dr. Sheffield Anti Itch Cream 20 mg/g; 1 mg/g 11527-0069-04 Sheffield 1 tube — — FDA listed —
Anti-itch 20 mg/g; 1 mg/g 11673-0895-28 Target 1 tube — — FDA listed —
Rite Aid Extra Strength Itch Stopping 1 mg/g; 20 mg/g 11822-6614-01 Rite 1 tube — — FDA listed —
signature care itch relief 2 g/100g; .1 g/100g 21130-0154-64 Safeway 1 tube — — FDA listed —
anti itch 2 g/100g; .1 g/100g 30142-0582-64 Kroger 1 tube — — FDA listed —
Shopko Anti-Itch 20 mg/g; 1 mg/g 37012-0089-02 Shopko 1 tube — — FDA listed —
itch relief 2 g/100g; .1 g/100g 37808-0622-64 H 1 tube — — FDA listed —
Anti-Itch Cream 1 mg/g; 20 mg/g 41226-0888-02 Kroger 1 tube — — FDA listed —
Anti Itch 2 g/100g; .1 g/100g 41250-0622-64 Meijer 1 tube — — FDA listed —
Equate Anti Itch 2 g/100g; .1 g/100g 49035-0622-64 Wal-Mart 1 tube — — FDA listed —
Diphenhydramine Hydrochloride and Zinc Acetate 20 mg/g; 1 mg/g 51672-2089-02 Sun 1 tube — — FDA listed —
CAREALL Anti-Itch 20 mg/g; 1 mg/g 51824-0088-01 New 35 g — — FDA listed —
Extra Strength Itch Stopping 20 mg/g; 1 mg/g 52000-0071-02 Universal 1 tube — — FDA listed —
Discount Drug Mart Extra Strength Itch Stopping 20 mg/g; 1 mg/g 53943-0258-01 Discount 1 tube — — FDA listed —
Family Wellness 2 g/100g; .1 g/100g 55621-0007-01 Zhejiang 1 tube — — FDA listed —
ItchZap 20 mg/g; 1 mg/g 57237-0352-28 Rising 1 tube — — FDA listed —
Itch Relief 2 g/100g; .1 g/100g 59779-0708-64 CVS 1 tube — — FDA listed —
Itch Relief Cream 2 g/100g; .1 g/100g 68016-0163-01 Pharmacy 1 tube — — FDA listed —
Anti-Itch Cream 2 g/100g; .1 g/100g 69396-0025-05 Trifecta 1 tube — — FDA listed —
Itch stopping Cream 2 g/100g; .1 g/100g 69396-0150-01 Trifecta 1 tube — — FDA listed —
itch relief 1 mg/g; 20 mg/g 69452-0449-37 Bionpharma 1 tube — — FDA listed —
Family Wellness 2 g/100g; .1 g/100g 69571-0005-02 FRONT 1 tube — — FDA listed —
CVS Extra Strength Itch Stopping 20 mg/g; 1 mg/g 69842-0321-28 CVS 1 tube — — FDA listed —
Benadryl Extra Strength Itch Stopping 20 mg/g; 1 mg/g 69968-0223-01 Kenvue 1 tube — — FDA listed —
TheraCare 2% Diphenhydramine Anti-Itch Cream 20 mg/g; 1 mg/g 71101-0014-01 Veridian 1 tube — — FDA listed —
Caring Mill Anti-Itch Cream 20 mg/g; 1 mg/g 71101-0055-01 Veridian 1 tube — — FDA listed —
Anti-Itch Cream 2 g/100g; .1 g/100g 83324-0039-01 Chain 1 tube — — FDA listed —
Savvy Itch Stopping 2 g/100g; .1 g/100g 83650-0102-01 Savvy 35.4 g — — FDA listed —
topcare anti itch 2 g/100g; .1 g/100g 36800-0622-64 Topco 1 tube — — FDA listed —
Itch Stopping 2 g/100g; .1 g/100g 42507-0622-64 HyVee 1 tube — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2005
On the market since
Dec 2005
📍
2026
Currently FDA-listed
21 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII 936JST6JCN
    Cetyl alcohol is a waxy, fatty substance derived from plant or animal sources. It acts as an emulsifier and thickener in medicines, helping blend oil and water components and giving products a smooth, creamy texture.
  • UNII H5RIZ3MPW4
    A chemical preservative used to prevent bacterial and fungal growth in medicines. It helps extend shelf life and maintain product safety during storage and use.
  • UNII 94YQ11Y95F
    A waxy substance made from glycol and fatty acids, used as an emulsifier and thickener to help blend oil and water ingredients together and give the medicine a smooth, uniform texture.
  • UNII A2I8C7HI9T
    Methylparaben is a preservative derived from benzoic acid that prevents growth of bacteria, fungi, and mold in medicines. It extends the product's shelf life and maintains safety during storage.
  • UNII NBX892EA57
    A synthetic compound made by combining polyethylene glycol with stearic acid. It acts as an emulsifier and surfactant to help mix oil and water-based ingredients, and improves how the medicine dissolves and spreads in the body.
  • UNII 6DC9Q167V3
    Propylene glycol is a clear liquid derived from petroleum or vegetable sources. It acts as a solvent, humectant, and preservative in medicines, helping dissolve active ingredients and maintain product stability.
  • UNII Z8IX2SC1OH
    Propylparaben is a chemical preservative used to prevent bacterial and fungal growth in medicines and personal care products. It helps extend shelf life and maintain product safety during storage.
  • UNII 059QF0KO0R
    Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.

8 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statescetyl alcohol, diazolidinyl urea, methylparaben, PEG-2 stearate, PEG-20 stearate, propylene glycol, propylparaben, purified water

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerPadagis Israel Pharmaceuticals Ltd
FDA applicationM017 (OTC MONOGRAPH DRUG)
Labeler code45802
First marketedDec 2005
Product typeHuman Otc Drug
Portfolio175 products on file

More NDCs from Padagis Israel Pharmaceuticals Ltd labeler code 45802

The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 📦 Storage and Handling 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose 📄 Do Not Use 📄 Ask a Doctor Before Use If 📄 When Using This Product 📄 Stop Use and Ask a Doctor If 📄 Keep Out of Reach of Children 📄 Questions or Comments 📄 Package Label / Principal Display Panel
🎯 Indications and Usage 51 words ▾

Uses • temporarily relieves pain and itching associated with: • insect bites • minor burns • sunburn • minor skin irritations • minor cuts • scrapes • rashes due to poison ivy, poison oak and poison sumac • dries the oozing and weeping of poison ivy, poison oak and poison sumac

⏱️ Dosage and Administration 40 words ▾

Directions • do not use more than directed • adults and children 2 years of age and older: apply to affected area no more than 3 to 4 times daily • children under 2 years of age: ask a doctor

⚠️ Warnings 103 words ▾

Warnings For external use only Do not use • on large areas of the body • with any other product containing diphenhydramine, even one taken by mouth Ask a doctor before use • on chicken pox • on measles When using this product • avoid contact with the eyes Stop use and ask a doctor if • condition worsens or does not improve within 7 days • symptoms persist for more than 7 days or clear up and occur again within a few days Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

📦 Storage and Handling 7 words ▾

Other information • store at 20°-25°C (68°-77°F)

🧪 Active Ingredient 8 words ▾

Active ingredients Diphenhydramine hydrochloride 2% Zinc acetate 0.1%

🧪 Inactive Ingredients 16 words ▾

Inactive ingredients cetyl alcohol, diazolidinyl urea, methylparaben, PEG-2 stearate, PEG-20 stearate, propylene glycol, propylparaben, purified water

🎯 Purpose 5 words ▾

Purpose Topical analgesic Skin protectant

📄 Do Not Use 22 words ▾

Do not use • on large areas of the body • with any other product containing diphenhydramine, even one taken by mouth

📄 Ask a Doctor Before Use If 12 words ▾

Ask a doctor before use • on chicken pox • on measles

📄 When Using This Product 10 words ▾

When using this product • avoid contact with the eyes

📄 Stop Use and Ask a Doctor If 35 words ▾

Stop use and ask a doctor if • condition worsens or does not improve within 7 days • symptoms persist for more than 7 days or clear up and occur again within a few days

📄 Keep Out of Reach of Children 19 words ▾

Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

📄 Questions or Comments 4 words ▾

Questions or comments? 1-800-719-9260

📄 Package Label / Principal Display Panel 68 words ▾

Principal Display Panel Extra Strength Itch Relief Cream • Relieves Itches from Insect Bites and Skin Irritations Compare to Extra Strength Benadryl® Cream active ingredients Diphenhydramine HCl & Zinc Acetate Extra Strength Itch Relief Cream Topical Analgesic • Skin Protectant NET WT 1 OZ (28 g) Padagis ™ DIPHENHYDRAMINE HCL & ZINC ACETATE CARTON IMAGE 1 OF 2 DIPHENHYDRAMINE HCL & ZINC ACETATE CARTON IMAGE 2 OF 2

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

Medicaid utilization & spend

📍 This exact package only: Medicaid data is reported per full 11-digit NDC — labeler, product and pack size — so every number here is for this package alone, not the drug overall. Other pack sizes report separately.
💊 Pharmacy benefit only: These are Medicaid outpatient pharmacy claims, billed by NDC. They exclude the medical benefit — clinic- or hospital-administered drugs billed under HCPCS J-codes — so drugs used mostly that way (e.g. Avastin, Lucentis, Keytruda) can look low or missing here. That’s expected, not an error.
📅 Q1 2025 – Q1 2026 · 5 quarters of data
ⓘ The newest quarter is usually incomplete when first published; states restate recent quarters in later CMS releases, so the latest figures typically revise upward. State coverage-policy changes can also shift quarter-to-quarter totals.
Prescriptions last 4 qtrs
457
Units reimbursed last 4 qtrs
13.7K
Gross reimbursed last 4 qtrs
$3.5K
Avg / prescription
$7.74
Avg / unit
$0.2590
Latest quarter Q1 2026
72Rx
Medicaid pays / g
$0.2590
gross reimbursed
vs
NADAC / g
$0.0575
acquisition cost
=
Spread
+$0.2015
+350% vs cost
What Medicaid paid per g (before rebates; includes the pharmacy’s dispensing fee) compared with NADAC — the average price pharmacies pay to buy the drug. A positive spread means Medicaid reimbursed more than the purchase price, before manufacturer rebates.
Fee-for-service vs managed care ⓘ
13% FFS 87% MCO
Fee-for-service · 60 Rx Managed care · 397 Rx
State Medicaid map
Alaska: no data reported AK Maine: no data reported ME Washington: no data reported WA Idaho: no data reported ID Montana: no data reported MT North Dakota: no data reported ND Minnesota: 2,545 units · 44.4 per 100k residents MN Wisconsin: no data reported WI Michigan: no data reported MI New York: no data reported NY Vermont: no data reported VT New Hampshire: no data reported NH Oregon: no data reported OR Nevada: no data reported NV Wyoming: no data reported WY South Dakota: no data reported SD Iowa: no data reported IA Illinois: no data reported IL Indiana: no data reported IN Ohio: 6,778 units · 57.5 per 100k residents OH Pennsylvania: no data reported PA New Jersey: 2,658 units · 28.6 per 100k residents NJ Massachusetts: no data reported MA California: no data reported CA Utah: no data reported UT Colorado: no data reported CO Nebraska: 980 units · 49.5 per 100k residents NE Missouri: no data reported MO Kentucky: no data reported KY West Virginia: no data reported WV Virginia: 336 units · 3.9 per 100k residents VA Maryland: no data reported MD Connecticut: 364 units · 10.1 per 100k residents CT Rhode Island: no data reported RI Arizona: no data reported AZ New Mexico: no data reported NM Kansas: no data reported KS Arkansas: no data reported AR Tennessee: no data reported TN North Carolina: no data reported NC South Carolina: no data reported SC Delaware: no data reported DE Oklahoma: no data reported OK Louisiana: no data reported LA Mississippi: no data reported MS Alabama: no data reported AL Georgia: no data reported GA D.C.: no data reported DC Hawaii: no data reported HI Texas: no data reported TX Florida: no data reported FL
Units reimbursed · per 100k residents
3.957.5
gray = no data reported ⓘ
Colors are per 100,000 residents, so big states don’t automatically dominate. Tap or hover a state for its actual totals.
Tap or hover a state
…for its Medicaid breakdown
🏆 Top states by units · per 100k residents
1 Ohio 57.5 /100k
2 Nebraska 49.5 /100k
3 Minnesota 44.4 /100k
4 New Jersey 28.6 /100k
5 Connecticut 10.1 /100k
6 Virginia 3.9 /100k
National units — by quarter
💵 About the dollar figures: “reimbursed” is what Medicaid paid pharmacies before confidential manufacturer rebates, so the program’s real net cost is lower than these numbers. Fee-for-service and managed-care claims are combined unless split above. Source: CMS State Drug Utilization Data; per-100k rates use 2023 Census population estimates.

Reported adverse events (FAERS)

Read carefully: FAERS reports are voluntary and unverified. Counts are not incidence, do not establish causation, are subject to reporting bias, and cannot be used to compare one drug to another. Shown for signal context only. Reports for Extra Strength Itch Relief — the ingredient across all brands.

Top reported reactions

Fatigue2
Headache2
Nausea2
Pruritus2
Anaemia1
Arthralgia1
Arthritis Bacterial1

Reporter sex

6 reports
Male · 67%
Female · 33%

Serious outcomes

Hospitalization1
Reports over time (by year) — tap or hover for the count & year
2024 2025 2026 2 2
Most recent year is provisional (FAERS lags ~3 months).
Where does this data come from?
Adverse-event reports from the FDA Adverse Event Reporting System (FAERS) via openFDA. FAERS reports are voluntary and unverified — counts are not incidence and don’t establish causation.
← 45802-0351-65 · Padagis 45802-0366-65 · Padagis →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.