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Sunmark Eye Drops Advanced Moisturizer/Lubricant Dextran, Polyethylene glycol 400, Povidone, Tetrahydrozoline 70 .1 g/100mL; 400 1 g/100mL; 1 g/100mL; .05 g/100mL Solution/ Drops — NDC 49348-0697-29 package photo

Sunmark Eye Drops Advanced Moisturizer/Lubricant Dextran, Polyethylene glycol 400, Povidone, Tetrahydrozoline 70 .1 g/100mL; 400 1 g/100mL; 1 g/100mL; .05 g/100mL Solution/ Drops

by Strategic Sourcing Services LLC · 1 BOTTLE, PLASTIC in 1 CARTON (49348-697-29) / 15 mL in 1 BOTTLE, PLASTIC
NDC 49348-0697-29
🏷️ FDA NDC (as labeled) 49348-697-29 billing pads the product segment with a zero
OTC On market Non-controlled
🗂️ Data synced Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

🆔 Identity & classification

FDA NDC (as labeled) 49348-697-29
Product NDC 49348-697
11-digit billing NDC 49348069729
NCPDP billing unit ML — per mL (volume)
RxCUI 996202
UNII 7SA290YK68, B697894SGQ, FZ989GH94E, 0YZT43HS7D
Application # M018
SPL Set ID 0daa4e39-0447-44b6-a7d7-370b12bf9451
Established class (EPC) Plasma Volume Expander
Mechanism of action Osmotic Activity
Physiologic effect Increased Intravascular Volume
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2007-03-01
Route OPHTHALMIC
Dosage form SOLUTION/ DROPS
Substance DEXTRAN 70; POLYETHYLENE GLYCOL 400; POVIDONE; TETRAHYDROZOLINE HYDROCHLORIDE
GPI-14 86409904502020
GPI class SM Eye Drops
GCN Seq No 050535
GCN 17625
HICL code 023805
Ingredient (HICL) Tetrahydroz/Dext 70/Peg 400/Pv
HIC1 code Q
Therapeutic class — broad (HIC1) Ear/Eye/Nose/Rectum/Topical/Vagina/Other
HIC2 code Q6
Therapeutic class — intermediate (HIC2) Ophthalmic Preparations
HIC3 code Q6D
Therapeutic class — specific (HIC3) Eye Vasoconstrictors (Otc Only)
AHFS code 52:32.00.00
AHFS class Vasoconstrictors
FDB label name SM EYE DROPS ADVANCED RELIEF
FDB brand name Eye Drops Advanced Relief
Legend status O — Over-the-counter (OTC) drug or device
Why two NDCs? The FDA registers this code as 49348-697-29 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 49348-0697-29. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

🏷️ RxNorm drug class

This medicine belongs to the Plasma Volume Expander class.

Pharmacologic class Plasma Volume Expander
How it works Osmotic Activity
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

🏭 Manufacturer & labeler

LabelerStrategic Sourcing Services LLC
FDA applicationM018 (OTC MONOGRAPH DRUG)
Labeler code49348
First marketedMar 2007
Product typeHuman Otc Drug
Portfolio316 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

🩺 Clinical

Label name SM EYE DROPS ADVANCED RELIEF Ingredient Tetrahydroz/Dext 70/Peg 400/Pv
📖 About the active ingredient MedlinePlus · NLM
General information about the ingredient itself — the description of this specific product follows below.

Ophthalmic tetrahydrozoline is used to relieve minor eye irritation and redness caused by colds, pollen, and swimming.

Read the full MedlinePlus article ↗
🧪 What is this product?

Sunmark Eye Drops Advanced Moisturizer/Lubricant is an over-the-counter eye drop product marketed under FDA's OTC monograph rules for lubricating eye drops. It contains dextran 70, polyethylene glycol 400, and povidone, which are lubricating and moisturizing agents typically used to coat and soothe the eye surface. Tetrahydrozoline hydrochloride is a decongestant commonly included in eye drops to help reduce redness. This product is intended for instillation directly into the eye.

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

🧪 Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII F5UM2KM3W7
    Benzalkonium chloride is a chemical compound that works as a preservative and antimicrobial agent in medications. It prevents bacterial and fungal growth in liquid formulations to keep the product safe during storage and use.
  • UNII R57ZHV85D4
    Boric acid is a weak acid derived from boron. In medicines, it typically serves as a buffer to help maintain the product's pH level and may act as a preservative in certain formulations.
  • UNII 7FLD91C86K
    Edetate disodium is a chemical compound that binds and removes certain metal ions. In medicines, it acts as a preservative and stabilizer by preventing metals like calcium from interfering with the product's shelf life and consistency.
  • UNII 91MBZ8H3QO
    Sodium borate is an inorganic salt compound used in medicines as a buffer to help maintain a stable pH level, and sometimes as a mild preservative or cleansing agent in topical formulations.
  • UNII 451W47IQ8X
    Sodium chloride is common table salt. It's used in medicines as a buffer to maintain proper pH, as a filler to add bulk, or to adjust the osmotic balance in liquid formulations.
  • UNII 059QF0KO0R
    Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.

6 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statesbenzalkonium chloride, boric acid, edetate disodium, purified water, sodium borate, and sodium chloride

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

💲 Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer mLPer package
Retail pharmacies payNADAC · weekly $0.154 $2.31 / 15 ml
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
NADAC price history (per mL) — tap or hover for the price & month
Dec 2021 Apr 2022 Aug 2022 Nov 2023 $0.154 $0.123
▲ Up 25% over the last 12 months.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

🔁 Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Leader Advanced Relief Eye Drops 70 100 mg/100mL; 400 1000 mg/100mL; 1000 mg/100mL; 50 mg/100mL 70000-0456-01 Cardinal 1 bottle $0.152 — Availability likely save 1%
Quality Choice Moisturizing Relief Eye Drops 70 .1 g/100mL; .05 g/100mL; 1 g/100mL; 400 1 g/100mL 83324-0191-14 Chain 1 bottle $0.152 — Availability likely save 1%
Sunmark Eye Drops Advanced Moisturizer/Lubricant 70 .1 g/100mL; 400 1 g/100mL; 1 g/100mL; .05 g/100mLthis 49348-0697-29 Strategic 1 bottle $0.154 — FDA listed —
Walgreens Eye Drops Advanced Relief 15mL 70 .1 g/100mL; 400 1 g/100mL; 1 g/100mL; .05 g/100mL 00363-4547-01 Walgreen 1 bottle — — FDA listed —
Signature Care Eye Drops Advanced Relief 70 100 mg/100mL; 400 1000 mg/100mL; 1000 mg/100mL; 50 mg/100mL 21130-0704-01 Better 1 bottle — — FDA listed —
Kroger Eye Drops Advanced Relief 70 .1 g/100mL; 400 1 g/100mL; 1 g/100mL; .05 g/100mL 30142-0836-01 Kroger 1 bottle — — FDA listed —
TopCare Health Advanced Moisturizing Plus Redness Relief 1 g/100mL; .05 g/100mL; 400 1 g/100mL; 70 .1 g/100mL 36800-0856-01 Topco 1 bottle — — FDA listed —
HEB Advanced Eye Drops 70 .1 g/100mL; 400 1 g/100mL; 1 g/100mL; .05 g/100mL 37808-0786-01 HEB 1 bottle — — FDA listed —
Equaline Advanced Relief Eye Drops 70 .1 g/100mL; 400 1 g/100mL; 1 g/100mL; .05 g/100mL 41163-0338-01 United 1 bottle — — FDA listed —
Meijer Advanced Redness and Irritation Relief 400 1 g/100mL; .05 g/100mL; 70 .1 g/100mL; 1 g/100mL 41250-0594-01 Meijer 1 bottle — — FDA listed —
GoodSense Eye Drops Advanced Relief Moisturizer 400 1 g/100mL; .05 g/100mL; 1 g/100mL; 70 .1 g/100mL 50804-0130-01 Geiss, 15 ml — — FDA listed —
CVS Advanced Eye Drops 70 .1 g/100mL; 400 1 g/100mL; 1 g/100mL; .05 g/100mL 51316-0129-01 CVS 1 bottle — — FDA listed —
Discount Drug Mart Eye Drops Advanced Relief 70 .1 g/100mL; 400 1 g/100mL; 1 g/100mL; .05 g/100mL 53943-0422-01 Discount 1 bottle — — FDA listed —
Exchange Select Eye Drops Advanced Relief Moisturizer 400 1 g/100mL; .05 g/100mL; 1 g/100mL; 70 .1 g/100mL 55301-0177-01 Army 1 bottle — — FDA listed —
Medics Choice Eye Drops Advanced 10 mg/mL; 400 10 mg/mL; .5 mg/mL; 70 1 mg/mL 55651-0025-01 KC 1 bottle — — FDA listed —
DG Health Advanced Relief Eye Drops 1 g/100mL; 70 .1 g/100mL; .05 g/100mL; 400 1 g/100mL 55910-0361-01 Dolgencorp 1 bottle — — FDA listed —
Publix Advanced Relief Eye Drops 70 .1 g/100mL; 400 1 g/100mL; 1 g/100mL; .05 g/100mL 56062-0084-01 Publix 1 bottle — — FDA listed —
Core Values Eye Drops Advanced Relief 70 .1 g/100mL; 400 1 g/100mL; 1 g/100mL; .05 g/100mL 63940-0344-01 Liberty 1 bottle — — FDA listed —
Best Choice Eye Drops Advanced Relief 70 .1 g/100mL; 400 1 g/100mL; 1 g/100mL; .05 g/100mL 63941-0942-15 Valu 1 bottle — — FDA listed —
Winco Advanced Relief Eye Drops 70 100 mg/100mL; 400 1000 mg/100mL; 1000 mg/100mL; 50 mg/100mL 67091-0282-15 WinCo 1 bottle — — FDA listed —
GoodSense Eye Drops Advanced Relief Moisturizer 400 1 g/100mL; .05 g/100mL; 1 g/100mL; 70 .1 g/100mL 68788-8635-01 Preferred 15 ml — — FDA listed —
Harris Teeter Eye Drops Advanced Relief 70 .1 g/100mL; 400 1 g/100mL; 1 g/100mL; .05 g/100mL 69256-0662-01 Harris 1 bottle — — FDA listed —
GoodSense Eye Drops Advanced Relief Moisturizer 400 1 g/100mL; .05 g/100mL; 1 g/100mL; 70 .1 g/100mL 85766-0165-15 Sportpharm 15 ml — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

⏳ Availability & generic status

🏛️
2007
On the market since
Mar 2007
📍
2026
Currently FDA-listed
19 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

📦 Packaging — all sizes for this product

Package NDCDescription Marketing startStatus
49348-0697-29 You're viewing this 1 BOTTLE, PLASTIC in 1 CARTON (49348-697-29) / 15 mL in 1 BOTTLE, PLASTIC 2007-03-01 Active

📄 FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose
🎯 Indications and Usage 25 words ▾

Uses relieves redness of the eye due to minor eye irritations as a lubricant to prevent further irritation or to relieve dryness of the eye

⏱️ Dosage and Administration 15 words ▾

Directions Instill 1 or 2 drops in the affected eye(s) up to four times daily.

⚠️ Warnings 126 words ▾

Warnings For external use only Ask a doctor before use if you have narrow angle glucoma When using this product pupils may become enlarged temporarily to avoid contamination, do not touch tip of container to any surface. Replace cap after using. if solution changes color or become cloudy, do not use overuse may produce increased redness of the eye remove contact lens before using Stop use and ask a doctor if you experience eye pain changes in vision continued redness or irritation of the eye, or if the condition worsens or persists for more than 72 hours If pregnant or breast-feeding ask a healthcare professional before use Keep out of reach of children If accidentally swallowed, get medical help or contact a Poison Control Center immediately

🧪 Active Ingredient 14 words ▾

Active Ingredients Dextran 70 0.1% povidone 1% Polyethylene glycol 400 1% Tetrahydrozoline HCL 0.05%

🧪 Inactive Ingredients 15 words ▾

Inactive Ingredients benzalkonium chloride, boric acid, edetate disodium, purified water, sodium borate, and sodium chloride

🎯 Purpose 5 words ▾

Purpose Eye Lubricant Redness reliever

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗
← 49348-0689-72 · Strategic 49348-0711-30 · Strategic →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.