HomeNDC LookupIngredientsGuaifenesin › 51660-0566-21
Guaifenesin 600 mg Tablet, Extended Release, 20-count — NDC 51660-0566-21 package photo

Guaifenesin 600 mg Tablet, Extended Release, 20-count

by Ohm Laboratories, Inc. · 20 TABLET, EXTENDED RELEASE in 1 CARTON (51660-566-21)
NDC 51660-0566-21
🏷️ FDA NDC (as labeled) 51660-566-21 billing pads the product segment with a zero
This package
Contains20-count Cost per ea$0.2854 NADAC Per package$5.71 / 20 tablets Pack sizes3 compare ↓
Also priced by: Medicaid pays $0.3406/unit — full pricing hub ↓
OTC Generic On market Non-controlled
🗂️ Data synced Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

🆔 Identity & classification

FDA NDC (as labeled) 51660-566-21
Product NDC 51660-566
11-digit billing NDC 51660056621
NCPDP billing unit EA — each (per item)
RxCUI 310621, 636522
UNII 495W7451VQ
Application # ANDA209254
SPL Set ID 7076e42a-17ff-4c42-9963-2dc02c0a5e49
Established class (EPC) Expectorant
Physiologic effect Decreased Respiratory Secretion Viscosity; Increased Respiratory Secretions
DEA schedule Non-controlled
Marketing category ANDA
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2022-04-01
Route ORAL
Dosage form TABLET, EXTENDED RELEASE
Substance GUAIFENESIN
GPI-14 43200010007420
GCN Seq No 071885
GCN 35905
HICL code 000271
Ingredient (HICL) Guaifenesin
HIC1 code B
Therapeutic class — broad (HIC1) Respiratory System
HIC2 code B3
Therapeutic class — intermediate (HIC2) Drugs Affecting Primarily The Trachea And Bronchi
HIC3 code B3J
Therapeutic class — specific (HIC3) Expectorants
AHFS code 48:16.00.00
AHFS class Expectorants
FDB label name GUAIFENESIN ER 600 MG TABLET
FDB brand name Guaifenesin Er
Legend status O — Over-the-counter (OTC) drug or device
Why two NDCs? The FDA registers this code as 51660-566-21 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 51660-0566-21. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

🏷️ RxNorm drug class

This medicine belongs to the Expectorant class.

Pharmacologic class Expectorant
Drug family (ATC) Expectorants
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

🏭 Manufacturer & labeler

LabelerOhm Laboratories, Inc.
Application holderOHM LABORATORIES INC
FDA applicationANDA209254 (ANDA)
Labeler code51660
First marketedApr 2022
Product typeHuman Otc Drug
Portfolio4 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

🩺 Clinical

Label name GUAIFENESIN ER 600 MG TABLET Ingredient Guaifenesin
📖 What it is MedlinePlus · NLM

Guaifenesin is used to relieve chest congestion. Guaifenesin may help control symptoms but does not treat the cause of symptoms or speed recovery. Guaifenesin is in a class of medications called expectorants. It works by thinning the mucus in the air passages to make it easier to cough up the mucus and clear the airways.

Read the full MedlinePlus article ↗
📗 Our plain-language guide HelloPharmacist
  • Guaifenesin is what's called an expectorant — it works to thin and loosen the mucus sitting in your chest and airways. That makes it easier to cough the mucus up and out, so instea...
  • What exactly does guaifenesin do for my cough?
  • Guaifenesin is meant for short-term use. If your cough isn't getting better after 7 days, keeps coming back, or shows up alongside a fever, rash, or a headache that won't go away,...
  • How long can I take it before I should call my doctor?
📖 Read our full Guaifenesin guide →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

💊 What it looks like

Color white
ShapeOval
ImprintRH;99
Size16 mm
ScoringNot scored
One label can cover several strengths, so colors may be combined — always confirm a loose pill against the dispensed prescription label or a pharmacist.
Where does this data come from?
Physical description (imprint, shape, color, scoring, coating) from this product’s FDA Structured Product Labeling (SPL), mirrored from DailyMed / openFDA.

🧪 Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII L06K8R7DQK
    A synthetic blue dye approved by the FDA for use in medications and foods. It serves as a colorant to make pills and liquids visually distinct and easier to identify.
  • UNII 3NXW29V3WO
    Hypromellose is a plant-based thickener made from cellulose. It's used in medicines as a binder to hold ingredients together, a coating for tablets, and a thickener for liquids.
  • UNII 70097M6I30
    Magnesium stearate is a salt made from magnesium and stearic acid, a fatty substance. It's used in tablets and capsules as a lubricant and glidant to help ingredients flow smoothly during manufacturing and prevent sticking.
  • UNII FZ989GH94E
    Povidone is a synthetic polymer made from a plastic-like material. It acts as a binder to hold tablet ingredients together and as a disintegrant to help the tablet break apart in your stomach so the medicine can be absorbed.
  • UNII ETJ7Z6XBU4
    Silicon dioxide is a naturally occurring mineral used as a glidant and anti-caking agent. It helps powder ingredients flow smoothly and prevents clumping during manufacturing and storage.

5 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statescolloidal silicon dioxide, FD&C blue # 2, aluminum lake, hypromellose, magnesium stearate, povidone.

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMedingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

💲 Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer eaPer package
Retail pharmacies payNADAC · weekly $0.285 $5.71 / 20 tablets
Medicaid paysCMS SDUD · 12 mo $0.3406 $6.81 / 20 tablets
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
NADAC price history (per ea) — tap or hover for the price & month
Dec 2023 Dec 2025 Apr 2026 Aug 2026 $0.357 $0.285
▼ Down 20% over the last 12 months.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

🔁 Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
good sense mucus er 600 mg 00113-2023-60 L. 20 tablets $0.285 Availability likely
Mucus Relief Extended Release 600 mg 00536-1163-61 Rugby 100 tablets $0.285 Availability likely
Mucus Relief ER 600 mg 00904-6718-39 Major 100 tablets $0.285 Availability likely
Mucus Relief 600 mg 00904-6986-40 Major 500 tablets $0.285 Availability likely
Guaifenesin 600 mg 46122-0750-51 AMERISOURCE 10 tablets $0.285 Availability likely
Guaifenesin 600 mgthis 51660-0566-21 Ohm 20 tablets $0.285 Availability likely
Mucus Relief 600 mg 63739-0067-02 McKesson 10 tablets $0.285 Availability likely
Guaifenesin Extended-Release 600 mg 68094-0048-61 Precision 10 tablets $0.285 Availability likely
Leader Mucus Relief 600 mg 70000-0758-01 Cardinal 20 tablets $0.285 Availability likely
Guaifenesin 600 mg 70010-0199-05 GRANULES 500 tablets $0.285 Availability likely
Foster and Thrive Mucus Relief 600 mg 70677-1013-01 Strategic 10 tablets $0.285 Availability likely
Mucus Relief 600 mg 70677-1052-01 Strategic 1 tablet $0.285 Availability likely
Guaifenesin 600 mg 70677-1257-01 Strategic 20 tablets $0.285 Availability likely
foster and thrive mucus relief 600 mg 70677-1291-01 Strategic 20 tablets $0.285 Availability likely
Mucus Relief 600 mg 83324-0097-20 CHAIN 20 tablets $0.285 Availability likely
Guaifenesin 600 mg 68001-0561-17 BluePoint 10 tablets $0.325 FDA listed +14%
Mucinex 600 mg 63824-0008-15 Reckitt 20 tablets $0.543 FDA listed +90%
Mucinex 600 mg 68084-0572-01 American 1 tablet $0.543 FDA listed +90%
Guaifenesin 600 mg 00363-0028-96 WALGREEN 20 tablets FDA listed
Mucus Relief Extended Release 600 mg 00363-0931-10 Walgreens 100 tablets Discontinued
Guaifenesin 600 mg 00363-9569-02 Walgreens 20 tablets FDA listed
Rugby Mucus Relief Er 600 mg 00536-1489-20 Rugby 20 tablets FDA listed
Mucus Relief 600 mg 00615-8637-39 NCS 30 tablets FDA listed
up and up mucus relief 600 mg 11673-0421-60 Target 20 tablets Discontinued
Guaifenesin 600 mg 11673-0539-02 TARGET 20 tablets FDA listed
Mucus Relief Extended-Release 600 mg 11673-0731-20 TARGET 20 tablets Discontinued
mucus relief 600 mg 11822-2123-01 Rite 20 tablets FDA listed
Mucus Relief 600 mg 11822-3252-07 Rite 40 tablets FDA listed
Mucinex 600 mg 17856-0008-02 ATLANTIC 1 tablet FDA listed
Guaifenesin 600 mg 21130-0179-67 Better 20 tablets FDA listed
Guaifenesin 600 mg 25000-0042-01 MARKSANS 20 tablets FDA listed
Guaifenesin 600 mg 30142-0961-20 Kroger 20 tablets FDA listed
Mucus Relief 600 mg 36800-0137-20 TOP 20 tablets Discontinued
Topco Mucus Relief 600 mg 36800-0226-16 Topco 100 tablets FDA listed
Mucus Relief 600 mg 37808-0830-20 H 20 tablets FDA listed
Mucus Relief 600 mg 37808-0935-40 H 40 tablets FDA listed
Mucus Relief 600 mg 37835-0408-40 Bi-Mart 40 tablets FDA listed
Mucus Relief 600 mg 41163-0731-20 United 20 tablets FDA listed
Mucus Relief 600 mg 41226-0723-02 KROGER 20 tablets FDA listed
mucus relief 600 mg 41250-0684-02 Meijer 20 tablets FDA listed
Guaifenesin 600 mg 41415-0996-20 Publix 20 tablets FDA listed
Mucus Relief Extended Release 600 mg 41520-0731-20 Care 20 tablets FDA listed
mucus er 600 mg 42507-0202-60 HyVee 20 tablets FDA listed
Mucus Relief 600 mg 42507-0253-03 HYVEE 20 tablets FDA listed
365 Whole Foods Market Guaifenesin 600 mg 42681-0057-01 Whole 20 tablets FDA listed
Guaifenesin 600 mg 43598-0008-40 Dr. 20 tablets FDA listed
Guaifenesin 600 mg 43598-0110-01 Dr. 20 tablets FDA listed
Guaifenesin Extended Release 600 mg 49483-0723-50 TIME 500 tablets FDA listed
Mucinex 600 mg 50090-0818-00 A-S 20 tablets FDA listed
Mucinex 600 mg 50090-1340-00 A-S 20 tablets FDA listed
Mucinex 600 mg 50090-2380-00 A-S 28 tablets FDA listed
Mucinex 600 mg 50090-6078-00 A-S 480 tablets FDA listed
Guaifenesin 600 mg 51316-0008-01 CVS 20 tablets FDA listed
Guaifenesin 600 mg 51316-0071-68 CVS 68 tablets FDA listed
Mucus And Chest Congestion 600 mg 51316-0299-01 CVS 20 tablets FDA listed
Mucus Relief 600 mg 51316-0470-01 CVS 20 tablets FDA listed
Mucus Relief 600 mg 53041-0190-16 Guardian 100 tablets FDA listed
Guaifenesin Extended-Release 600 mg 53041-0233-30 Guardian 10 tablets FDA listed
Mucus Relief 600 mg 53942-0203-02 Demoulas 20 tablets FDA listed
Mucus Relief 600 mg 53943-0233-32 Discount 10 tablets FDA listed
Mucus Relief ER 600 mg 55154-4153-00 Cardinal 10 tablets FDA listed
Mucinex 600 mg 55154-4680-00 Cardinal 1 tablet FDA listed
MUCUS RELIEF GUAIFENESIN EXTENDED-RELEASE 600 mg 55681-0301-01 TWIN 100 tablets FDA listed
Mucus Relief 600 mg 55910-0739-20 Dolgencorp, 20 tablets FDA listed
DG Health Mucus ER 600 mg 55910-0904-01 Dolgencorp, 20 tablets FDA listed
Mucus Relief 600 mg 57344-0203-02 AAA 10 tablets FDA listed
Crcle Guaifenesin Extended-Release Tablets, 600 mg 57483-0270-01 Innovus 100 tablets FDA listed
Giltuss EX Expectorant 600 mg 58552-0338-07 Gil 7 tablets FDA listed
Giltuss Diabetic Ex 600 mg 58552-0339-07 Gil 7 tablets FDA listed
Giltuss HBP EX Expectorant 600 mg 58552-0340-07 Gil 7 tablets FDA listed
Guaifenesin 600 mg 58602-0810-12 Aurohealth 40 tablets FDA listed
Guaifenesin 600 mg 58602-0853-12 Aurohealth 40 tablets FDA listed
Guaifenesin 600 mg 58602-0864-98 Aurohealth 20 tablets FDA listed
Mucus Relief 600 mg 59726-0734-20 P 1 tablet FDA listed
Guaifenesin 600 mg 62207-0570-30 Granules 20000 tablets FDA listed
Guaifenesin 600 mg 62207-0839-72 Granules 10 tablets FDA listed
Mucinex 600 mg 63187-0954-20 Proficient 20 tablets FDA listed
Mucinex 600 mg 63629-7115-01 Bryant 30 tablets FDA listed
Mucinex 600 mg 63629-7886-01 Bryant 20 tablets FDA listed
12 Hour Mucus Relief 600 mg 63868-0149-20 CHAIN 10 tablets FDA listed
Mucus Relief 600 mg 63941-0731-20 Best 20 tablets FDA listed
Guaifenesin 600 mg 65162-0036-02 Amneal 10 tablets FDA listed
Mucus Relief 600 mg 67091-0370-20 WinCo 20 tablets FDA listed
Mucus Relief 600 mg 67091-0403-02 WINCO 10 tablets FDA listed
Mucus Relief Extended Release 600 mg 67296-1467-07 Redpharm 1 tablet FDA listed
good sense mucus er 600 mg 67296-2223-02 Redpharm 20 tablets FDA listed
Mucinex 600 mg 67544-0149-53 Aphena 60 tablets FDA listed
Mucus Relief 600 mg 69168-0459-02 Allegiant 150 tablets FDA listed
Mucus Relief 600 mg 69256-0731-20 Harris 1 tablet FDA listed
mucus 600 mg 69842-0806-01 CVS 20 tablets FDA listed
Guaifenesin 600 mg 69848-0017-02 GRANULES 20 tablets FDA listed
Mucus Relief 600 mg 71335-2642-01 Bryant 30 tablets FDA listed
Mucus Relief 600 mg 71610-0499-12 Aphena 12 tablets FDA listed
Mucus Relief 600 mg 72036-0203-02 HARRIS 20 tablets FDA listed
Mucus Relief 600 mg 72090-0011-01 Pioneer 200 tablets FDA listed
basic care mucus er 600 mg 72288-0298-02 Amazon.com 20 tablets FDA listed
Curist Mucus Relief 600 mg 72559-0017-22 Little 200 tablets FDA listed
Guaifenesin 600 mg 73581-0400-02 YYBA 200 tablets FDA listed
MUCUS RELIEF GUAIFENESIN EXTENDED-RELEASE 600 mg 73581-0401-02 YYBA 200 tablets FDA listed
Topcare mucus er 600 mg 76162-0123-58 Topco 40 tablets FDA listed
Guaifenesin 600 mg 79903-0124-20 Walmart 20 tablets FDA listed
Guaifenesin Extended Release 600 mg 79903-0271-40 Wal-Mart 20 tablets FDA listed
equate mucus-er 600 mg 79903-0292-12 WALMART 40 tablets FDA listed
Mucus Relief 600 mg 80513-0403-20 Advanced 200 tablets FDA listed
Mucus Relief 600 mg 81522-0203-02 FSA 20 tablets FDA listed
Guaifenesin 600 mg 82804-0265-20 Proficient 20 tablets FDA listed
Mucus Relief 600 mg 84324-0026-01 NUVICARE 40 tablets FDA listed
Dr. Simi Mucus Relief 600 mg 85786-0302-40 Farmacias 20 tablets FDA listed
Mucus Relief 600 mg 85828-0723-02 Grocery 20 tablets FDA listed
Guaifenesin 600 mg 87448-1701-02 Northwestern 1 tablet Discontinued
About this product: this is a generic version of the medicine. FDA equivalence ratings are shown when available, and other versions are listed above, least expensive first.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2022
On the market since
Apr 2022
📍
2026
Currently FDA-listed
4 years listed
🔓
·
Generic on the market
this product is a generic
This is a generic drug

This product is an FDA-approved generic. Other versions of the same drug are listed under Therapeutic equivalents, least expensive first.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

🗺️ Medicaid utilization & spend

📍 This exact package only: Medicaid data is reported per full 11-digit NDC — labeler, product and pack size — so every number here is for 51660-0566-21, not the drug overall. Other pack sizes report separately.
💊 Pharmacy benefit only: These are Medicaid outpatient pharmacy claims, billed by NDC. They exclude the medical benefit — clinic- or hospital-administered drugs billed under HCPCS J-codes — so drugs used mostly that way (e.g. Avastin, Lucentis, Keytruda) can look low or missing here. That’s expected, not an error.
📅 Q1 2025 – Q4 2025 · 4 quarters of data
ⓘ The newest quarter is usually incomplete when first published; states restate recent quarters in later CMS releases, so the latest figures typically revise upward. State coverage-policy changes can also shift quarter-to-quarter totals.
Prescriptions last 4 qtrs
3K
Units reimbursed last 4 qtrs
87K
Gross reimbursed last 4 qtrs
$29.6K
Avg / prescription
$9.99
Avg / unit
$0.3406
Latest quarter Q4 2025
756Rx
Medicaid pays / ea
$0.3406
gross reimbursed
vs
NADAC / ea
$0.2854
acquisition cost
=
Spread
+$0.0552
+19% vs cost
What Medicaid paid per ea (before rebates; includes the pharmacy’s dispensing fee) compared with NADAC — the average price pharmacies pay to buy the drug. A positive spread means Medicaid reimbursed more than the purchase price, before manufacturer rebates.
Fee-for-service vs managed care
97% MCO
Fee-for-service · 87 Rx Managed care · 2,881 Rx
State Medicaid map
Alaska: no data reported AK Maine: no data reported ME Washington: 7,295 units · 93.4 per 100k residents WA Idaho: no data reported ID Montana: no data reported MT North Dakota: no data reported ND Minnesota: 2,752 units · 48.0 per 100k residents MN Wisconsin: no data reported WI Michigan: no data reported MI New York: no data reported NY Vermont: 368 units · 56.9 per 100k residents VT New Hampshire: no data reported NH Oregon: 5,153 units · 122 per 100k residents OR Nevada: 1,747 units · 54.7 per 100k residents NV Wyoming: no data reported WY South Dakota: no data reported SD Iowa: no data reported IA Illinois: 2,106 units · 16.8 per 100k residents IL Indiana: 2,733 units · 39.8 per 100k residents IN Ohio: 7,357 units · 62.4 per 100k residents OH Pennsylvania: 8,553 units · 66.0 per 100k residents PA New Jersey: 8,019 units · 86.3 per 100k residents NJ Massachusetts: no data reported MA California: no data reported CA Utah: no data reported UT Colorado: no data reported CO Nebraska: 2,729 units · 138 per 100k residents NE Missouri: no data reported MO Kentucky: 4,675 units · 103 per 100k residents KY West Virginia: no data reported WV Virginia: 10,855 units · 125 per 100k residents VA Maryland: 4,814 units · 77.9 per 100k residents MD Connecticut: no data reported CT Rhode Island: no data reported RI Arizona: 13,527 units · 182 per 100k residents AZ New Mexico: no data reported NM Kansas: no data reported KS Arkansas: no data reported AR Tennessee: no data reported TN North Carolina: no data reported NC South Carolina: 798 units · 14.9 per 100k residents SC Delaware: 679 units · 65.9 per 100k residents DE Oklahoma: no data reported OK Louisiana: no data reported LA Mississippi: no data reported MS Alabama: no data reported AL Georgia: no data reported GA D.C.: 390 units · 57.4 per 100k residents DC Hawaii: 2,492 units · 174 per 100k residents HI Texas: no data reported TX Florida: no data reported FL
Units reimbursed · per 100k residents
14.9182
gray = no data reported
Colors are per 100,000 residents, so big states don’t automatically dominate. Tap or hover a state for its actual totals.
Tap or hover a state
…for its Medicaid breakdown
🏆 Top states by units · per 100k residents
1 Arizona 182 /100k
2 Hawaii 174 /100k
3 Nebraska 138 /100k
4 Virginia 125 /100k
5 Oregon 122 /100k
6 Kentucky 103 /100k
7 Washington 93.4 /100k
8 New Jersey 86.3 /100k
National units — by quarter
💵 About the dollar figures: “reimbursed” is what Medicaid paid pharmacies before confidential manufacturer rebates, so the program’s real net cost is lower than these numbers. Fee-for-service and managed-care claims are combined unless split above. Source: CMS State Drug Utilization Data; per-100k rates use 2023 Census population estimates.

💊 Medicaid utilization by pack size

Medicaid (SDUD) totals over the four most recent reported quarters for every package size of this drug — handy when a specific package (e.g. a starter/titration pack) carries little or no Medicaid volume on its own.
20 tablets this page51660-0566-21 2,968 Rx · $29,649
40 tablets51660-0566-41 No Medicaid data
68 tablets51660-0566-68 No Medicaid data
Drug total (last 4 qtrs): 2,968 Rx · 87,042 units · $29,649 gross reimbursed
Tap a pack size to open its page. Source: CMS State Drug Utilization Data, last 4 quarters.

📦 Packaging — all sizes for this product

Package NDCDescription Per unit Per pack Marketing startStatus
51660-0566-21 You're viewing this 20 TABLET, EXTENDED RELEASE in 1 CARTON (51660-566-21) $0.2854 / ea $5.71 2022-04-01 Active
51660-0566-41 40 TABLET, EXTENDED RELEASE in 1 CARTON (51660-566-41) 2022-04-01 Active
51660-0566-68 68 TABLET, EXTENDED RELEASE in 1 CARTON (51660-566-68) 2026-01-17 Active

You're viewing the smallest of 3 pack sizes for this product.

In Medicaid, this is the most-dispensed pack of this product — about 100% of fills over the last four reported quarters. See all packs ↓

Pack size FAQ

What quantity is in NDC 51660-0566-21?
NDC 51660-0566-21 is a 20-count package — 20 tablet, extended release in 1 carton.
What is the difference between NDC 51660-0566-21 and NDC 51660-0566-41?
Both are Guaifenesin 600 mg Tablet, Extended Release — the drug itself is identical. NDC 51660-0566-21 is the 20-count package, while NDC 51660-0566-41 is the 40 tablets package.
What NDC number is used to bill for this package of Guaifenesin 600 mg Tablet, Extended Release?
Bill NDC 51660-0566-21 — the 11-digit billing format is 51660056621. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.

Prices are the latest CMS NADAC pharmacy acquisition cost per NDC; per-pack figures are per-unit × pack quantity, shown only when the pack is denominated in the same measure NADAC prices.

📄 FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage 22 words

Uses Helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bronchial mucus and make coughs more productive

⏱️ Dosage and Administration 89 words

Directions do not crush, chew or break extended-release tablet take with a full glass of water this product can be administered without regard for the timing of meals adults and children over 12 years of age and over: one or two extended-release tablets every 12 hours. Do not exceed 4 extended-release tablets in 24 hours. children under 12 years of age: do not use. Other information store between 20-25°C (68-77°F) TAMPER EVIDENT: DO NOT USE IF CARTON IS OPEN OR IF PRINTED SEAL ON BLISTER IS BROKEN OR MISSING.

⚠️ Warnings 80 words

Warnings Do not use for children under 12 years of age Ask a doctor before use if you have persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis, or emphysema cough accompanied by too much phlegm (mucus) Stop use and ask a doctor if cough lasts more than 7 days, comes back or occurs with fever, rash, or persistent headache. These could be signs of serious illness. If pregnant or breast-feeding, ask a health professional before use.

🧪 Active Ingredient 8 words

Active ingredient (in each extended-release tablet) Guaifenesin, USP

🧪 Inactive Ingredients 29 words

Inactive Ingredients colloidal silicon dioxide, FD&C blue # 2, aluminum lake, hypromellose, magnesium stearate, povidone. Questions call toll-free Monday to Friday 8:30 am to 5:00 pm EST at 1-800-406-7984.

🎯 Purpose 2 words

Purpose Expectorant

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.