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Vcf Contraceptive Pre-Filled Applicators NONOXYNOL-9 4 g/100g Gel, Metered, 10 applicators — NDC 52925-0512-10 package photo
Label image from the product's FDA listing (DailyMed) — may show a different pack size or an older label revision.

Vcf Contraceptive Pre-Filled Applicators NONOXYNOL-9 4 g/100g Gel, Metered, 10 applicators — NDC 52925-512-10 (Billing 52925-0512-10)

by APOTHECUS PHARMACEUTICAL CORP · 10 APPLICATOR in 1 BOX / 2.55 g in 1 APPLICATOR

This is a package of 10 applicators of Vcf Contraceptive Pre-Filled Applicators NONOXYNOL-9 4 g/100g Gel, Metered from APOTHECUS PHARMACEUTICAL CORP, marketed since Jun 2014 and currently FDA-listed. It is the main listing for this product, which comes in 2 package sizes.

NDC 52925-0512-10
🏷️ FDA NDC (as labeled) 52925-512-10 billing pads the product segment with a zero
This package
Contains10 applicators Pack sizes2 compare ↓
Main listing for product 52925-512 · Also comes in: 250 applicators 52925-512-25
OTC On market Non-controlled ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 1, 2026 · this listing last changed Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

NDC database record

One package, one record: these facts belong to NDC 52925-512-10 alone.

Record
FDA NDC Directory package listing · Human OTC drug
Code segments
52925 labeler · 512 product · 10 package
Package marketed since
Jun 1, 2014
Sample package
No — commercial package
Listing certified through
Dec 31, 2026
Barcode (UPC-A, from the NDC)
3 5292551210 7
FDA record last changed
Jul 24, 2026
🚨
Active recall for this product.
Class II · Nov 22, 2024 — CGMP deviations: out of specifications for assay (Apothecus Pharmaceutical Corp.) · FDA recall D-0151-2025
Lots / codes: Lot: 3A001/3A001A, Exp: 07/25 · reported Dec 25, 2024
Check your lot/expiration against the official notice — look up the recall number in the FDA recall database ↗

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 52925-512-10
Product NDC 52925-512
11-digit billing NDC 52925051210
NCPDP billing unit GM — per gram (weight)
RxCUI 198765, 1597814
UNII 48Q180SH9T
Application # 505G(a)(3)
SPL Set ID 34be97cd-3646-427d-8112-ba0030ff8d88
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2014-06-01
Route VAGINAL
Dosage form GEL, METERED
Substance NONOXYNOL-9

Drug-database identifiers Medi-Span GPI and First Databank GCN / HICL / AHFS classification

GPI-14 55300010004040
GPI class VCF Vaginal Contraceptive
GCN Seq No 011979
GCN 11551
HICL code 001462
Ingredient (HICL) Nonoxynol 9
HIC1 code G
Therapeutic class — broad (HIC1) Female Genital System
HIC2 code G9
Therapeutic class — intermediate (HIC2) Intravaginal Antifertility Agents
HIC3 code G9A
Therapeutic class — specific (HIC3) Contraceptives,Intravaginal
AHFS code 32:00.00.00
AHFS class Nonhormonal Contraceptives
FDB label name VCF CONTRACEPTIVE GEL
FDB brand name Vcf
Legend status O — Over-the-counter (OTC) drug or device
Quick answers
  • GSN (GCN sequence number): 011979
  • GCN: 11551
  • GPI-14 (Medi-Span): 55300010004040
  • HICL (First Databank): 001462
  • AHFS class code: 32:00.00.00
  • RxCUI (RxNorm): 198765
Why two NDCs? The FDA registers this code as 52925-512-10 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 52925-0512-10. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

Clinical

Label name VCF CONTRACEPTIVE GEL Ingredient Nonoxynol 9
🧪 What is this product?

VCF Contraceptive Pre-Filled Applicators is a vaginal gel containing nonoxynol-9, an over-the-counter contraceptive product marketed under FDA guidelines for its category. Nonoxynol-9 is a spermicide typically used as a barrier contraceptive method to reduce the chances of pregnancy. The product comes in metered pre-filled applicators for convenience. This is a non-hormonal contraceptive option that some people use alone or alongside other birth control methods.

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer gPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Try another pack size: 250 applicators
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Marketing startMarketing endStatus
52925-0512-10 You're viewing this Main listing 10 APPLICATOR in 1 BOX / 2.55 g in 1 APPLICATOR 2014-06-01 — Active
52925-0512-25 52925-512-25 250 APPLICATOR in 1 CARTON / 2.55 g in 1 APPLICATOR 2014-06-01 — Active

Pack size FAQ

What quantity is in this package?
This package contains 10 applicators — 10 applicator in 1 box / 2.55 g in 1 applicator.
How does this package differ from NDC 52925-0512-25?
Both are Vcf Contraceptive Pre-Filled Applicators NONOXYNOL-9 4 g/100g Gel, Metered — the drug itself is identical. This page's package is the 10 applicators one, while NDC 52925-0512-25 is the 250 applicators package.
What NDC number is used to bill for this package of Vcf Contraceptive Pre-Filled Applicators NONOXYNOL-9 4 g/100g Gel, Metered?
Use the 11-digit billing form listed in the identifiers section of this page. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Vcf Contraceptive Pre-Filled Applicators 4 g/100gthis 52925-0512-10 APOTHECUS 10 applicators — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2014
On the market since
Jun 2014
📍
2026
Currently FDA-listed
12 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

What it looks like

Color White
One label can cover several strengths, so colors may be combined — always confirm a loose pill against the dispensed prescription label or a pharmacist.
Where does this data come from?
Physical description (imprint, shape, color, scoring, coating) from this product’s FDA Structured Product Labeling (SPL), mirrored from DailyMed / openFDA.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII 420IP921MB
    A chelating agent derived from edetic acid that binds to metals in the formulation. It helps stabilize the medicine by preventing metal ions from causing breakdown or discoloration.
  • UNII 33X04XA5AT
    Lactic acid is a naturally occurring organic acid derived from milk or plant sources. It lowers and maintains pH in formulations, helps preserve the product, and can enhance ingredient stability and absorption.
  • UNII A2I8C7HI9T
    Methylparaben is a preservative derived from benzoic acid that prevents growth of bacteria, fungi, and mold in medicines. It extends the product's shelf life and maintains safety during storage.
  • UNII 1VPU26JZZ4
    Potassium sorbate is a salt derived from sorbic acid, a naturally occurring preservative. It prevents growth of mold, yeast, and some bacteria, extending the medicine's shelf life.
  • UNII U725QWY32X
    Povidone K30 is a synthetic polymer made from petroleum. It acts as a binder to hold tablet ingredients together and as a disintegrant to help the tablet break apart in the stomach so the medicine can be absorbed.
  • UNII 6DC9Q167V3
    Propylene glycol is a clear liquid derived from petroleum or vegetable sources. It acts as a solvent, humectant, and preservative in medicines, helping dissolve active ingredients and maintain product stability.
  • UNII OJ245FE5EU
    Sodium benzoate is a salt derived from benzoic acid, a preservative. It's added to medicines to prevent growth of bacteria, fungi, and other microorganisms that could spoil the product.
  • UNII 506T60A25R
    Sorbitol is a natural sugar alcohol derived from glucose. It serves as a sweetener, humectant, and bulking agent in medications to improve taste and help maintain moisture in the product.
  • UNII 059QF0KO0R
    Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.

9 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statespurified water, propylene glycol, CMC 7MF, sorbitol solution, PVP K 30, simethicone, lactic acid, methyl paraben, potassium sorbate, sodium benzoate, trisodium EDTA

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerAPOTHECUS PHARMACEUTICAL CORP
FDA application505G(a)(3) (OTC MONOGRAPH DRUG)
Labeler code52925
First marketedJun 2014
Product typeHuman Otc Drug

More NDCs from APOTHECUS PHARMACEUTICAL CORP labeler code 52925

The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 📦 Storage and Handling 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose 📄 Do Not Use 📄 Stop Use and Ask a Doctor If 📄 Keep Out of Reach of Children 📄 Questions or Comments 📄 Package Label / Principal Display Panel
🎯 Indications and Usage 10 words ▾

Use for the prevention of pregnancy with condom or alone

⏱️ Dosage and Administration 57 words ▾

Directions For maximum protection against unwanted pregnancy, follow the enclosed directions exactly. Insert one applicatorful into the vagina prior to intercourse (see complete, illustrated directions on package insert). Each applicatorful is effective immediately and up to one hour after application. An additional applicatorful is required prior to each act of intercourse, regardless of time since last application.

⚠️ Warnings 111 words ▾

Warnings For Vaginal Use Only Not for rectal (anal) use. Sexually Transmitted Disease (STDs) alert This product does not protect against HIV (AIDS) or other STDs and may increase the risk of getting HIV from an infected partner. Do not use if you or your sex partner has HIV/AIDS.

If you do not know if you or your sex partner is infected, choose another form of birth control Stop use and ask a doctor if you or your partner get burning, itching, a rash, or other irritation of the vagina or penis. Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

📦 Storage and Handling 90 words ▾

Other Information When used correctly every time you have sex, latex condoms greatly reduce, but do not eliminate, the risk of catching or spreading HIV, the virus that causes AIDS. Use a latex condom without nonoxynol-9 if you or your sex partner has HIV/AIDS, multiple sex partners, or other HIV risk factors. VCF ® is tested by independent laboratories for determination of sperm inactivating qualities, using the I.P.P.F. agreed protocol Store at room temperature, 59° - 86° F (15° - 30° C).

Avoid exposure to extremes of hot and cold.

🧪 Active Ingredient 4 words ▾

Active Ingredient Nonoxynol-9, (4%)

🧪 Inactive Ingredients 24 words ▾

Inactive Ingredients purified water, propylene glycol, CMC 7MF, sorbitol solution, PVP K 30, simethicone, lactic acid, methyl paraben, potassium sorbate, sodium benzoate, trisodium EDTA

🎯 Purpose 3 words ▾

Purpose Vaginal Contraceptive

📄 Do Not Use 30 words ▾

Do not use if you or your sex partner has HIV/AIDS. If you do not know if you or your sex partner is infected, choose another form of birth control

📄 Stop Use and Ask a Doctor If 24 words ▾

Stop use and ask a doctor if you or your partner get burning, itching, a rash, or other irritation of the vagina or penis.

📄 Keep Out of Reach of Children 19 words ▾

Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

📄 Questions or Comments 20 words ▾

Questions? If you have any questions, call our toll-free line at 1-800-879-2393 between 9:00AM and 5:00PM EST, Monday through Friday.

📄 Package Label / Principal Display Panel 56 words ▾

PRINCIPAL DISPLAY PANEL - 2.55 g Applicator Box New! Compare To CONCEPTROL ® ! VCF ® Vaginal Contraceptive Gel FOR PREVENTION OF PREGNANCY Pre-Filled Applicators Safe and effective Hormone free Easy to use Contains the Spermicide Doctors Recommend Most 10 PRE-FILLED APPLICATORS NET WT. 0.09 oz. (2.55g) EACH PRINCIPAL DISPLAY PANEL - 2.55 g Applicator Box

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

Reported adverse events (FAERS)

Read carefully: FAERS reports are voluntary and unverified. Counts are not incidence, do not establish causation, are subject to reporting bias, and cannot be used to compare one drug to another. Shown for signal context only. Reports for VCF CONTRACEPTIVE PRE-FILLED APPLICATORS (this brand).

Top reported reactions

Dyspareunia2
Dysuria2
Vulvovaginal Discomfort2
Vulvovaginal Swelling2
Burning Sensation1
Diarrhoea1
Dysmenorrhoea1

Reporter sex

9 reports
Female · 100%

Serious outcomes

Hospitalization1
Life-threatening1
Disabling1
Reports over time (by year) — tap or hover for the count & year
2019 2021 2023 2026 2 0
Most recent year is provisional (FAERS lags ~3 months).
Where does this data come from?
Adverse-event reports from the FDA Adverse Event Reporting System (FAERS) via openFDA. FAERS reports are voluntary and unverified — counts are not incidence and don’t establish causation.

About this NDC listing & data coverage

Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The form printed on the packaging and shown on DailyMed is the one the FDA registered. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero and the dashes are dropped. The Identity section at the top of this page lists each form of this code.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by APOTHECUS PHARMACEUTICAL CORP. Listing status can change — the directory data on this page refreshes weekly.
Does this product come in other package sizes?
Yes — the FDA directory lists 1 other package presentation of this same product, including 250 applicators (52925-0512-25). Each has its own NDC and its own page — see the package list near the top of this page.
Who lists this product with the FDA?
APOTHECUS PHARMACEUTICAL CORP is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
← 52925-0112-01 · APOTHECUS 52928-0001-04 · Joyang →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.