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Breakout Control Bioelements Benzoyl Peroxide 5 g/100mL Cream — NDC 56152-4009-2 (Billing 56152-4009-02)

by Cosmetic Enterprises Ltd · 1 BOTTLE in 1 CARTON / 29 mL in 1 BOTTLE

This is a package of Breakout Control Bioelements Benzoyl Peroxide 5 g/100mL Cream from Cosmetic Enterprises Ltd, marketed since Jun 2013 and currently FDA-listed. It is this product's only package size.

NDC 56152-4009-02
🏷️ FDA NDC (as labeled) 56152-4009-2 billing pads the package segment with a zero
OTC On market Non-controlled ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 1, 2026 · this listing last changed Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

NDC database record

One package, one record: these facts belong to NDC 56152-4009-2 alone.

Record
FDA NDC Directory package listing · Human OTC drug
Code segments
56152 labeler · 4009 product · 2 package
Package marketed since
Jun 14, 2013
Sample package
No — commercial package
Listing certified through
Dec 31, 2026
Barcode (UPC)
0836490001919
FDA record last changed
Jul 24, 2026
⚠️
Other active recalls for Benzoyl Peroxide (different manufacturers) — 1 · tap to view
These affect other manufacturers’ products for the same ingredient — not necessarily the exact NDC on this page.
Class II · Feb 24, 2025 — Chemical Contamination: Presence of benzene. (Denison Pharmaceuticals, LLC) · FDA recall D-0273-2025
Each entry is an official FDA enforcement report — look up any recall number in the FDA recall database ↗

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 56152-4009-2
Product NDC 56152-4009
11-digit billing NDC 56152400902
RxCUI 308693
UNII W9WZN9A0GM
UPC 0836490001919
Application # M006
SPL Set ID 94462332-2169-4ea1-86b3-25ab9646c6e5
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2013-06-14
Route TOPICAL
Dosage form CREAM
Substance BENZOYL PEROXIDE
Quick answers
  • RxCUI (RxNorm): 308693
Why two NDCs? The FDA registers this code as 56152-4009-2 — a 5-4-1 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the package segment → 56152-4009-02. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

RxNorm drug class

This medicine belongs to the Peroxides class.

Drug family (ATC) Peroxides
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

Clinical

📗 Our plain-language guide HelloPharmacist
  • Most products are for acne. They dry up pimples and help prevent new ones. Epsolay is a prescription cream for rosacea bumps in adults. The Folliculitis Treatment Cream products ar...
  • For many acne products, start with once a day. You can move up to two or three times daily if your skin tolerates it. If you get dryness or peeling, cut back to once daily or every...
  • Redness, dryness, peeling, itching, and stinging or burning are the usual ones. Using less often can help. Using another acne product at the same time makes irritation more likely.
  • Stop if irritation gets severe. Stop right away and get help if you have hives, swelling or trouble breathing. Those can be signs of a serious allergic reaction.
📖 Read our full Benzoyl Peroxide guide →

Supplement & herbal interactions

Some supplements/herbs that may interact with Benzoyl Peroxide — tap one for details:

Dimethylsulfoxide (dmso)Moderate Turpentine OilModerate AlchemillaMinor
🌿 Every supplement checked against Benzoyl Peroxide (3 interactions) — ranked by severity →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer gPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Marketing startMarketing endStatus
56152-4009-02 You're viewing this Main listing 1 BOTTLE in 1 CARTON / 29 mL in 1 BOTTLE 2013-06-14 — Active

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Proactiv Emergency Blemish Relief 5 g/100g 11410-0012-09 Alchemee, 1 tube — — FDA listed —
ACNE FORTE Acne Treatment Cream 50 mg/mL 52063-0709-00 GSCM 1 jar — — FDA listed —
SERIOUS SKINCARE Continuously Clear Clearz It 50 mg/mL 53755-0392-00 Flageoli 59 ml — — FDA listed —
Breakout Control Bioelements 5 g/100mLthis 56152-4009-02 Cosmetic 1 bottle — — FDA listed —
Dermisa Acne Treatment 5 g/100g 68343-0123-01 Montani 28 g — — FDA listed —
PCA SKIN Acne 5 g/100g 68726-0169-04 CP 1 jar — — FDA listed —
Face Reality 5% Advanced Acne Med 50 mg/mL 70707-0157-01 Face 1 tube — — FDA listed —
MD-Acne Body Acne Treatment 50 mg/mL 71804-0230-06 MD 180 ml — — FDA listed —
MDacne Body Acne Treatment Benzoyl Peroxide 50 mg/mL 71804-0532-00 MDAlgorithms 90 ml — — FDA listed —
MDacne Customized Acne Treatment Benzoyl Peroxide 50 mg/mL 71804-0536-00 MDAlgorithms 1 tube — — FDA listed —
Monat Acne Treatment 5 g/100mL 78518-0295-01 Monat 15 ml — — FDA listed —
BLAIR and JACK Anti-Bump Acne Treatment 50 mg/mL 84377-0489-00 Blair 1 jar — — FDA listed —
Clear Med 5% 5 g/100mL 70764-0106-51 CONTROL 1 tube — — FDA listed —
PCA SKIN BPO Cleanser 5 g/100mL 68726-0168-04 CP 1 bottle — — FDA listed —
Anti Bac Acne Clearing 5 g/100mL 56152-4012-01 Cosmetic 50 ml — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2013
On the market since
Jun 2013
📍
2026
Currently FDA-listed
13 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

🧪 Avoiding an ingredient? See Benzoyl Peroxide inactive ingredients by manufacturer: every current product's list side by side, so you can ask your pharmacy for the version that does not list it.

Loading inactive ingredients from the official FDA label in the background. No external source is being called by this page request.
Where does this data come from?
Source: official FDA Structured Product Labeling (SPL) via DailyMed and the openFDA label index. Structured IACT rows and label-wide narrative are kept separate; availability and product-level specificity depend on the submitted label.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerCosmetic Enterprises Ltd
FDA applicationM006 (OTC MONOGRAPH DRUG)
Labeler code56152
First marketedJun 2013
Product typeHuman Otc Drug
Portfolio20 products on file

More NDCs from Cosmetic Enterprises Ltd labeler code 56152

The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose 📄 Keep Out of Reach of Children 📄 Package Label / Principal Display Panel
🎯 Indications and Usage ~1 min read ▾

Stop use and ask a doctor if: irritation becomes severe Warnings For external use only When using this product - Skin irritation and dryness is more likely to occur if you use antoher topical acne medication at the same time. If irritation occurs only use only one topical acne medication at a time. - Avoid unnecessary sun exposure and use a sunscreen - Avoid contact with with the eyes lips and mouth - Avoid contact with hair and dyed fabrics, which may be bleached by this product - Skin irritation may occur, characterized by redness, burning, itching, peeling or possibly swelling .

Irritation may be reduced by using the product less frequently or in a lower concentration. - Do not use if you: Have very sensitive skin Are sensitive to benzoyl peroxide Directions Cleanse the skin thoroughly before applying this product cover the entire with a thin layer one to three times daily Because excessive drying of the skin may occur, start with one application daily then gradually increase to two or three times daily if needed or as directed by a doctor If bothersome dryness or peeling occurs, reduce application to once a day or every other day If going outside apply sunscreen after using this product.

If irritation or sensitivity develops stop use of both products and ask a doctor. Inactive ingredients Water (Aqua,Eau), Pentylene Glycol, Hydroxyethyl Acrylates/Sodium Acryloyldimethyl Taurate Copolymer, Squalene, Polysorbate 60, Aloe Bardadensis (Aloe) Leaf Juice powder, Phytic Acid, Phyenoxyethanol, Potassium Sorbate, Disodium EDTA.

⏱️ Dosage and Administration 117 words ▾

Directions Cleanse the skin thoroughly before applying this product cover the entire with a thin layer one to three times daily Because excessive drying of the skin may occur, start with one application daily then gradually increase to two or three times daily if needed or as directed by a doctor If bothersome dryness or peeling occurs, reduce application to once a day or every other day If going outside apply sunscreen after using this product. If irritation or sensitivity develops stop use of both products and ask a doctor.

Inactive ingredients Water (Aqua,Eau), Pentylene Glycol, Hydroxyethyl Acrylates/Sodium Acryloyldimethyl Taurate Copolymer, Squalene, Polysorbate 60, Aloe Bardadensis (Aloe) Leaf Juice powder, Phytic Acid, Phyenoxyethanol, Potassium Sorbate, Disodium EDTA.

⚠️ Warnings ~1 min read ▾

Warnings For external use only When using this product - Skin irritation and dryness is more likely to occur if you use antoher topical acne medication at the same time. If irritation occurs only use only one topical acne medication at a time. - Avoid unnecessary sun exposure and use a sunscreen - Avoid contact with with the eyes lips and mouth - Avoid contact with hair and dyed fabrics, which may be bleached by this product - Skin irritation may occur, characterized by redness, burning, itching, peeling or possibly swelling .

Irritation may be reduced by using the product less frequently or in a lower concentration. - Do not use if you: Have very sensitive skin Are sensitive to benzoyl peroxide Directions Cleanse the skin thoroughly before applying this product cover the entire with a thin layer one to three times daily Because excessive drying of the skin may occur, start with one application daily then gradually increase to two or three times daily if needed or as directed by a doctor If bothersome dryness or peeling occurs, reduce application to once a day or every other day If going outside apply sunscreen after using this product.

If irritation or sensitivity develops stop use of both products and ask a doctor. Inactive ingredients Water (Aqua,Eau), Pentylene Glycol, Hydroxyethyl Acrylates/Sodium Acryloyldimethyl Taurate Copolymer, Squalene, Polysorbate 60, Aloe Bardadensis (Aloe) Leaf Juice powder, Phytic Acid, Phyenoxyethanol, Potassium Sorbate, Disodium EDTA.

🧪 Active Ingredient ~1 min read ▾

Active ingredient Purpose Benzoyl Peroxide 5% Acne treatment Uses For the treatment of acne Helps prevent new acne blemishes Keep out of reach of children. If swallowed get medical help or contact Poison Control Center right away Stop use and ask a doctor if: irritation becomes severe Warnings For external use only When using this product - Skin irritation and dryness is more likely to occur if you use antoher topical acne medication at the same time. If irritation occurs only use only one topical acne medication at a time. - Avoid unnecessary sun exposure and use a sunscreen - Avoid contact with with the eyes lips and mouth - Avoid contact with hair and dyed fabrics, which may be bleached by this product - Skin irritation may occur, characterized by redness, burning, itching, peeling or possibly swelling .

Irritation may be reduced by using the product less frequently or in a lower concentration. - Do not use if you: Have very sensitive skin Are sensitive to benzoyl peroxide Directions Cleanse the skin thoroughly before applying this product cover the entire with a thin layer one to three times daily Because excessive drying of the skin may occur, start with one application daily then gradually increase to two or three times daily if needed or as directed by a doctor If bothersome dryness or peeling occurs, reduce application to once a day or every other day If going outside apply sunscreen after using this product.

If irritation or sensitivity develops stop use of both products and ask a doctor. Inactive ingredients Water (Aqua,Eau), Pentylene Glycol, Hydroxyethyl Acrylates/Sodium Acryloyldimethyl Taurate Copolymer, Squalene, Polysorbate 60, Aloe Bardadensis (Aloe) Leaf Juice powder, Phytic Acid, Phyenoxyethanol, Potassium Sorbate, Disodium EDTA.

🧪 Inactive Ingredients 27 words ▾

Inactive ingredients Water (Aqua,Eau), Pentylene Glycol, Hydroxyethyl Acrylates/Sodium Acryloyldimethyl Taurate Copolymer, Squalene, Polysorbate 60, Aloe Bardadensis (Aloe) Leaf Juice powder, Phytic Acid, Phyenoxyethanol, Potassium Sorbate, Disodium EDTA.

🎯 Purpose ~1 min read ▾

Uses For the treatment of acne Helps prevent new acne blemishes Keep out of reach of children. If swallowed get medical help or contact Poison Control Center right away Stop use and ask a doctor if: irritation becomes severe Warnings For external use only When using this product - Skin irritation and dryness is more likely to occur if you use antoher topical acne medication at the same time. If irritation occurs only use only one topical acne medication at a time. - Avoid unnecessary sun exposure and use a sunscreen - Avoid contact with with the eyes lips and mouth - Avoid contact with hair and dyed fabrics, which may be bleached by this product - Skin irritation may occur, characterized by redness, burning, itching, peeling or possibly swelling .

Irritation may be reduced by using the product less frequently or in a lower concentration. - Do not use if you: Have very sensitive skin Are sensitive to benzoyl peroxide Directions Cleanse the skin thoroughly before applying this product cover the entire with a thin layer one to three times daily Because excessive drying of the skin may occur, start with one application daily then gradually increase to two or three times daily if needed or as directed by a doctor If bothersome dryness or peeling occurs, reduce application to once a day or every other day If going outside apply sunscreen after using this product.

If irritation or sensitivity develops stop use of both products and ask a doctor. Inactive ingredients Water (Aqua,Eau), Pentylene Glycol, Hydroxyethyl Acrylates/Sodium Acryloyldimethyl Taurate Copolymer, Squalene, Polysorbate 60, Aloe Bardadensis (Aloe) Leaf Juice powder, Phytic Acid, Phyenoxyethanol, Potassium Sorbate, Disodium EDTA.

📄 Keep Out of Reach of Children ~1 min read ▾

Keep out of reach of children. If swallowed get medical help or contact Poison Control Center right away Stop use and ask a doctor if: irritation becomes severe Warnings For external use only When using this product - Skin irritation and dryness is more likely to occur if you use antoher topical acne medication at the same time. If irritation occurs only use only one topical acne medication at a time. - Avoid unnecessary sun exposure and use a sunscreen - Avoid contact with with the eyes lips and mouth - Avoid contact with hair and dyed fabrics, which may be bleached by this product - Skin irritation may occur, characterized by redness, burning, itching, peeling or possibly swelling .

Irritation may be reduced by using the product less frequently or in a lower concentration. - Do not use if you: Have very sensitive skin Are sensitive to benzoyl peroxide Directions Cleanse the skin thoroughly before applying this product cover the entire with a thin layer one to three times daily Because excessive drying of the skin may occur, start with one application daily then gradually increase to two or three times daily if needed or as directed by a doctor If bothersome dryness or peeling occurs, reduce application to once a day or every other day If going outside apply sunscreen after using this product.

If irritation or sensitivity develops stop use of both products and ask a doctor. Inactive ingredients Water (Aqua,Eau), Pentylene Glycol, Hydroxyethyl Acrylates/Sodium Acryloyldimethyl Taurate Copolymer, Squalene, Polysorbate 60, Aloe Bardadensis (Aloe) Leaf Juice powder, Phytic Acid, Phyenoxyethanol, Potassium Sorbate, Disodium EDTA.

📄 Package Label / Principal Display Panel 22 words ▾

Bioelements Breakout control 5% benzoyl peroxide acne treatment invisibly spot treats to clear acne breakouts 29 mL/ 1 Fl. Oz. Bottle Box

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

Medicare Part D spend CMS · PART D · 2026 (Q1)

Medicare Part D (outpatient prescription) spending for Epsolay (matched by generic name) — the program that covers self-administered drugs. 1 manufacturer.
⚠️ Drug-level data: CMS publishes Part D spending by drug, not by NDC — these figures combine every manufacturer, strength and package size sold under the name Epsolay. That’s a different level of aggregation than the Medicaid card above, which is specific to this exact 11-digit NDC (pack size included), so the two aren’t directly comparable.
Period
Total Part D spend
$60.9K
Claims incl. refills
82
Beneficiaries
63
Spend / beneficiary
$967.04
Spend / claim
$742.97
Trend by period
💵 About the dollar figures: spending is what Part D plans paid before confidential manufacturer rebates, so the program’s real net cost is lower. A blank patient count means fewer than 11 people — CMS hides counts that small to protect privacy. Source: CMS Medicare Quarterly Part D Spending by Drug (data.cms.gov), updated quarterly.

About this NDC listing & data coverage

Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos — Not published for this NDC No photo available yet for this listing.
Inactive ingredients (structured) — Not published for this NDC The labeler did not submit a structured excipient list, or no SPL is available.
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The form printed on the packaging and shown on DailyMed is the one the FDA registered. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero and the dashes are dropped. The Identity section at the top of this page lists each form of this code.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by Cosmetic Enterprises Ltd. Listing status can change — the directory data on this page refreshes weekly.
Who lists this product with the FDA?
Cosmetic Enterprises Ltd is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
← 56152-4008-02 · Cosmetic 56152-4012-01 · Cosmetic →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.