Senna Syrup Sennosides 8.8 mg/5mL Liquid, 237 mL
by Rising Pharma Holdings, Inc. · 237 mL in 1 BOTTLE (57237-301-24)
NDC 57237-0301-24
🏷️ FDA NDC (as labeled)
57237-301-24
billing pads the product segment with a zero
OTC
On market
Non-controlled
🗂️ Data synced Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →
🆔 Identity & classification
FDA NDC (as labeled)
57237-301-24
Product NDC
57237-301
11-digit billing NDC
57237030124
NCPDP billing unit
ML — per mL (volume)
RxCUI
702311
UNII
3FYP5M0IJX
Application #
M007.60
SPL Set ID
dc636b83-6eca-412e-bac5-0c736b371ca7
DEA schedule
Non-controlled
Marketing category
OTC MONOGRAPH DRUG
Marketing status
On market
FDA listing status
Listed (active directory)
Marketing start
2022-09-27
Route
ORAL
Dosage form
LIQUID
Substance
SENNOSIDES
GPI-14
46200060201220
GCN Seq No
002922
GCN
08660
HICL code
001289
Ingredient (HICL)
Sennosides
HIC1 code
D
Therapeutic class — broad (HIC1)
Biliary System/Gastro-Intestinal System
HIC2 code
D6
Therapeutic class — intermediate (HIC2)
Drugs Acting Principally On The Colon
HIC3 code
D6S
Therapeutic class — specific (HIC3)
Laxatives And Cathartics
AHFS code
56:12.00.00
AHFS class
Cathartics And Laxatives
FDB label name
SENNA 8.8 MG/5 ML SYRUP
FDB brand name
Senna
Legend status
O — Over-the-counter (OTC) drug or device
Why two NDCs?
The FDA registers this code as 57237-301-24 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 57237-0301-24. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.
🏷️ RxNorm drug class
This medicine belongs to the Contact laxatives class.
Drug family (ATC)
Contact laxatives
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.
🏭 Manufacturer & labeler
LabelerRising Pharma Holdings, Inc.
FDA applicationM007.60 (OTC MONOGRAPH DRUG)
Labeler code57237
First marketedSep 2022
Product typeHuman Otc Drug
Portfolio525 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.
🩺 Clinical
Label name SENNA 8.8 MG/5 ML SYRUP Ingredient Sennosides
📖 What it is MedlinePlus · NLM
Senna is used on a short-term basis to treat constipation. It also is used to empty the bowels before surgery and certain medical procedures. Senna is in a class of medications called stimulant laxatives. It works by increasing activity of the intestines to cause a bowel movement.
Read the full MedlinePlus article ↗📗 Our plain-language guide HelloPharmacist
- Senna typically produces a bowel movement within 6 to 12 hours. That's why most people take it at bedtime — so it can do its job overnight and you get results in the morning. If no...
- How long does it take for senna to work?
- Senna is designed for short-term, occasional use. You should not use it for more than 1 week unless your doctor specifically tells you it's okay. Using laxatives too often or for t...
- Laxatives like senna can affect how your body absorbs other medications. To be safe, take senna at least 2 hours before or after any other drugs you use. It's always a good idea to...
Patient education
Supplement & herbal interactions
Some supplements/herbs that may interact with Sennosides (OTC drug) — tap one for details:
3
Nutrient depletion considerations
Sennosides (OTC drug) may be associated with lower levels of 3 nutrients — worth a chat with your pharmacist, not a cause for alarm.
An association is not a deficiency. Educational only — don't start or stop anything without professional guidance.
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.
💬 Questions about Sennosides?
Ask a pharmacist →
Ask a licensed pharmacist directly — free, answered by our team.
💊 What it looks like
Color
brown
FlavorChocolate
One label can cover several strengths, so colors may be combined — always confirm a loose pill against the dispensed prescription label or a pharmacist.
Where does this data come from?
Physical description (imprint, shape, color, scoring, coating) from this product’s FDA Structured Product Labeling (SPL), mirrored from DailyMed / openFDA.
🧪 Inactive Ingredients / Excipients
Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.
Loading inactive ingredients from the official FDA label in the background. No external source is being called by this page request.
Where does this data come from?
Source: official FDA Structured Product Labeling (SPL) via DailyMed and the openFDA label index. Structured
IACT rows and label-wide narrative are kept separate; availability and product-level specificity depend on the submitted label.Inactive ingredient FAQ
Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.
💲 Pricing
A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.
| Price system | Per mL | Per package |
|---|---|---|
| Retail pharmacies payNADAC · weekly | $0.038 | $8.89 / 237 ml |
| Medicaid paysCMS SDUD · 12 mo | $0.0583 | $13.82 / 237 ml |
| Medicare drug plans payPart D · quarterly | No Part D plan price is available for this NDC in our data. | |
NADAC price history (per mL) — tap or hover for the price & month
▲ Up 7% over the last 12 months.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.
🔁 Therapeutic equivalents
| Product | Labeler | Pack | NADAC/unit | TE | Status | Price vs. this |
|---|---|---|---|---|---|---|
| Senna Liquid 8.8 mg/5mL 00536-1266-59 | RUGBY | 237 ml | $0.038 | — | Availability likely | — |
| Senna 8.8 mg/5mL 39328-0020-08 | Patrin | 237 ml | $0.038 | — | Availability likely | — |
| Senna Syrup 8.8 mg/5mL 54859-0808-08 | Llorens | 237 ml | $0.038 | — | Availability likely | — |
| Senna Syrup 8.8 mg/5mLthis 57237-0301-24 | Rising | 237 ml | $0.038 | — | Availability likely | — |
| Senna Syrup 8.8 mg/5mL 58657-0518-08 | Method | 237 ml | $0.038 | — | Availability likely | — |
| Senna 8.8 mg/5mL 82568-0024-08 | AARNA | 237 ml | $0.038 | — | Availability likely | — |
| Senna 8.8 mg/5mL 00121-4967-40 | PAI | 10 cups | — | — | FDA listed | — |
| Senna 8.8 mg/5mL 00536-1483-59 | Rugby | 237 ml | — | — | FDA listed | — |
| Senna 8.8 mg/5mL 00904-7528-94 | Major | 10 cups | — | — | FDA listed | — |
| OneLAX SENNA 417.12 mg/237mL 17856-1127-01 | ATLANTIC | 120 syringes | — | — | FDA listed | — |
| OneLAX SENNA 417.12 mg/237mL 17856-8127-02 | Atlantic | 50 cups | — | — | FDA listed | — |
| Senna UD 8.8 mg/5mL 39328-0120-50 | Patrin | 10 cups | — | — | FDA listed | — |
| Senna UD 26.4 mg/15mL 39328-0220-50 | Patrin | 10 cups | — | — | FDA listed | — |
| Senna Syrup 8.8 mg/5mL 48433-0219-40 | Safecor | 40 cups | — | — | FDA listed | — |
| Senna Syrup 8.8 mg/5mL 50268-0731-24 | AVPAK | 24 cups | — | — | FDA listed | — |
| Senna Syrup 8.8 mg/5mL 57237-0310-54 | Rising | 40 cups | — | — | FDA listed | — |
| GeriCare Senna Syrup 8.8 mg/5mL 57896-0472-08 | Geri-Care | 237 ml | — | — | FDA listed | — |
| Senna 8.8 mg/5mL 60687-0851-77 | American | 10 cups | — | — | FDA listed | — |
| Senna Syrup 8.8 mg/5mL 63629-9268-01 | Bryant | 237 ml | — | — | FDA listed | — |
| SENNA Syrup 8.8 mg/5mL 66424-0562-08 | SDA | 236 ml | — | — | FDA listed | — |
| Senna 417.12 mg/237mL 68094-0049-62 | Precision | 10 cups | — | — | FDA listed | — |
| Senna 8.8 mg/5mL 69618-0069-58 | Reliable | 237 ml | — | — | FDA listed | — |
| OneLAX SENNA 417.12 mg/237mL 71399-0027-08 | Akron | 237 ml | — | — | FDA listed | — |
| Senna Syrup 8.8 mg/5mL 72090-0022-01 | Pioneer | 237 ml | — | — | FDA listed | — |
| Senna Syrup 8.8 mg/5mL 72162-1672-02 | Bryant | 237 ml | — | — | FDA listed | — |
| Senna Syrup 8.8 mg/5mL 73564-0812-08 | Aldama | 1 bottle | — | — | FDA listed | — |
| Senna Syrup 8.8 mg/5mL 81033-0120-50 | Kesin | 50 cups | — | — | FDA listed | — |
| Senna Syrup 8.8 mg/5mL 84415-0021-01 | Everpharm | 100 cups | — | — | FDA listed | — |
| Senna Liquid 8.8 mg/5mL 84447-0120-01 | Belleview | 200000 ml | — | — | FDA listed | — |
| Curewell Senna Syrup 8.8 mg/5mL 85111-0452-08 | RMT | 1 bottle | — | — | FDA listed | — |
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.
⏳ Availability & generic status
🏛️
2022
On the market since
Sep 2022
📍
2026
Currently FDA-listed
4 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found
We did not find an FDA-approved generic match for this exact strength, form and route.
Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.
🗺️ Medicaid utilization & spend
📍 This exact package only: Medicaid data is reported per full 11-digit NDC — labeler, product and pack size — so every number here is for 57237-0301-24, not the drug overall. Other pack sizes report separately.
💊 Pharmacy benefit only: These are Medicaid outpatient pharmacy claims, billed by NDC. They exclude the medical benefit — clinic- or hospital-administered drugs billed under HCPCS J-codes — so drugs used mostly that way (e.g. Avastin, Lucentis, Keytruda) can look low or missing here. That’s expected, not an error.
📅 Q1 2025 – Q1 2026 · 5 quarters of data
ⓘ The newest quarter is usually incomplete when first published; states restate recent quarters in later CMS releases, so the latest figures typically revise upward. State coverage-policy changes can also shift quarter-to-quarter totals.
Prescriptions last 4 qtrs
27.1K
Units reimbursed last 4 qtrs
6M
Gross reimbursed last 4 qtrs
$347.7K
Avg / prescription
$12.81
Avg / unit
$0.0583
Latest quarter Q1 2026
6.5KRx
Medicaid pays / mL
$0.0583
gross reimbursed
vs
NADAC / mL
$0.0375
acquisition cost
=
Spread
+$0.0208
+55% vs cost
What Medicaid paid per mL (before rebates; includes the pharmacy’s dispensing fee) compared with NADAC — the average price pharmacies pay to buy the drug. A positive spread means Medicaid reimbursed more than the purchase price, before manufacturer rebates.
Fee-for-service vs managed care ⓘ
Fee-for-service · 11,880 Rx Managed care · 15,263 Rx
State Medicaid map
Units reimbursed · per 100k residents
25.07,231
gray = no data reported ⓘ
Colors are per 100,000 residents, so big states don’t automatically dominate. Tap or hover a state for its actual totals.
Tap or hover a state
…for its Medicaid breakdown
Prescriptions—
Units—
Reimbursed—
🏆 Top states by units · per 100k residents
National units — by quarter
💵 About the dollar figures: “reimbursed” is what Medicaid paid pharmacies before confidential manufacturer rebates, so the program’s real net cost is lower than these numbers. Fee-for-service and managed-care claims are combined unless split above. Source: CMS State Drug Utilization Data; per-100k rates use 2023 Census population estimates.
🔬 Reported adverse events (FAERS)
Read carefully: FAERS reports are voluntary and unverified. Counts are not incidence, do not establish causation, are subject to reporting bias, and cannot be used to compare one drug to another. Shown for signal context only. Reports for Senna Syrup (this brand).
Top reported reactions
Age at onset
Reporter sex
Male · 48%
Female · 52%
Unknown · 0%
Serious outcomes
Reports over time (by year) — tap or hover for the count & year
Most recent year is provisional (FAERS lags ~3 months).
Where does this data come from?
Adverse-event reports from the FDA Adverse Event Reporting System (FAERS) via openFDA. FAERS reports are voluntary and unverified — counts are not incidence and don’t establish causation.
📦 Packaging — all sizes for this product
| Package NDC | Description | Marketing start | Status |
|---|---|---|---|
| 57237-0301-24 You're viewing this | 237 mL in 1 BOTTLE (57237-301-24) | 2022-09-27 | Active |
📄 FDA label — Drug Facts FDA SPL
The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage
⏱️ Dosage and Administration
⚠️ Warnings
🤰 Pregnancy
📦 Storage and Handling
🧪 Active Ingredient
🧪 Inactive Ingredients
🎯 Purpose
🎯 Indications and Usage ▾
Uses relieves occasional constipation (irregularity) generally causes bowel movement in 6 to 12 hours
⏱️ Dosage and Administration ▾
Directions shake well before using Do not exceed recommended dose Age Starting Dose Maximum Dose adults and children 12 years and older 2 to 3 teaspoonfuls once a day preferably at bedtime; increase as needed or as recommended by a doctor 3 teaspoonfuls in the morning and 3 teaspoonfuls at bedtime Under 12 years of age ask a doctor ask a doctor
⚠️ Warnings ▾
Warnings Do not use laxative products for longer than 1 week unless directed by a doctor. Ask a doctor before use if you have stomach pain, nausea or vomitting noticed a change in bowel habits that lasts over two weeks. Stope use and ask a doctor if you have rectal bleeding or failure to have a bowel movement after use of laxative. These may indicate a serious condition.
🤰 Pregnancy ▾
If pregnant or breast-feeding, ask a health professional before use.
📦 Storage and Handling ▾
Other information store at room temperature 15° to 25° C (59° to 77° F) TAMPER-EVIDENT: Do not use if foil seal over bottle opening is torn, broken, or missing.
🧪 Active Ingredient ▾
Senna Syrup Active ingredient (in each 5 mL teaspoonful) Sennosides - 8.8 mg
🧪 Inactive Ingredients ▾
Inactive ingredients: artificial and natural chocolate flavor, methylparaben, propylene glycol, propylparaben, purified water, sucrose.
🎯 Purpose ▾
Purpose Laxative
No label section mentions that — try another word, or open the full label on DailyMed below.
Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA.
Prefer the government’s original formatting? View this label on DailyMed ↗
For educational and professional reference only — not medical advice. Pricing reflects published
NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.