Methimazole 10 mg Tablet, 100-count
🆔 Identity & classification
Where does this data come from?
🏷️ RxNorm drug class
This medicine belongs to the Thyroid Hormone Synthesis Inhibitor class.
Where does this data come from?
🏭 Manufacturer & labeler
Where does this data come from?
🩺 Clinical
Methimazole is used to treat hyperthyroidism, a condition that occurs when the thyroid gland produces too much thyroid hormone. It is also taken before thyroid surgery or radioactive iodine therapy. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
Read the full MedlinePlus article ↗- Methimazole tells your thyroid gland to stop making so much thyroid hormone. When your thyroid is overactive — like in Graves' disease — it pumps out too much hormone and speeds ev...
- What exactly is methimazole supposed to do for me?
- Usually you'll take it in three separate doses spaced about 8 hours apart throughout the day — so think morning, afternoon, and evening. Your prescriber sets the exact dose based o...
- How do I take it — do I take it all at once?
Patient education
Supplement & herbal interactions
Some supplements/herbs that may interact with Methimazole — tap one for details:
Where does this data come from?
Ask a licensed pharmacist directly — free, answered by our team.
💊 What it looks like
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🧪 Inactive Ingredients / Excipients
Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.
💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.
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Anhydrous lactose is a milk sugar with no water content. It acts as a filler and binder in tablets and capsules, adding bulk and helping ingredients stick together.
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Lactose monohydrate is a natural sugar derived from milk. It serves as a filler and binder in tablets and capsules, helping create the proper size, texture, and consistency of the medicine.
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Magnesium stearate is a salt made from magnesium and stearic acid, a fatty substance. It's used in tablets and capsules as a lubricant and glidant to help ingredients flow smoothly during manufacturing and prevent sticking.
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Silicon dioxide is a naturally occurring mineral used as a glidant and anti-caking agent. It helps powder ingredients flow smoothly and prevents clumping during manufacturing and storage.
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A plant-based carbohydrate derived from corn kernels. It acts as a filler to add bulk, a binder to hold ingredients together, and a disintegrant to help the tablet break apart in your stomach for absorption.
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A powder made from a naturally occurring mineral. In medicines, talc works as a glidant and anti-caking agent, helping tablets and capsules flow smoothly during manufacturing and preventing clumping.
6 inactive ingredients listed in the exact product block matched to this NDC.
Where does this data come from?
ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.Inactive ingredient FAQ
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💲 Pricing
A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.
| Price system | Per each | Per package |
|---|---|---|
| Retail pharmacies payNADAC · weekly | Not in the retail survey — common for institutional, discontinued, or low-volume packs. | |
| Medicaid paysCMS SDUD · 12 mo | No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data. | |
| Medicare drug plans payPart D · Q2 2026 | $0.1781 | $17.81 / 100 tablets |
Where does this data come from?
🔁 Therapeutic equivalents
| Product | Labeler | Pack | NADAC/unit | TE | Status | Price vs. this |
|---|---|---|---|---|---|---|
| Methimazole 10 mg 00832-6073-11 | Upsher-Smith | 100 tablets | $0.125 | AB | Availability likely | — |
| Methimazole 10 mg 11788-0012-01 | AiPing | 100 tablets | $0.125 | AB | Availability likely | — |
| Methimazole 10 mg 23155-0071-01 | Heritage | 100 tablets | $0.125 | AB | Availability likely | — |
| Methimazole 10 mg 33342-0336-11 | Macleods | 100 tablets | $0.125 | AB | Availability likely | — |
| Methimazole 10 mg 50268-0496-15 | AvPAK | 50 tablets | $0.125 | AB | Availability likely | — |
| Methimazole 10 mg 60687-0680-01 | American | 100 tablets | $0.125 | AB | Availability likely | — |
| Methimazole 10 mg 64380-0213-01 | Strides | 100 tablets | $0.125 | AB | Availability likely | — |
| Methimazole 10 mg 64980-0265-01 | Rising | 100 tablets | $0.125 | AB | Availability likely | — |
| Methimazole 10 mg 69452-0329-20 | Bionpharma | 100 tablets | $0.125 | AB | Availability likely | — |
| methimazole 10 mg 72578-0213-01 | Viona | 100 tablets | $0.125 | AB | Availability likely | — |
| Methimazole 10 mg 72603-0316-01 | NORTHSTAR | 100 tablets | $0.125 | AB | Availability likely | — |
| Methimazole 10 mg 60429-0381-01 | Golden | 100 tablets | — | AB | FDA listed | — |
| Methimazole 10 mgthis 62135-0206-01 | Chartwell | 100 tablets | — | AB | FDA listed | — |
| Methimazole 10 mg 63629-9251-01 | Bryant | 100 tablets | — | AB | FDA listed | — |
| methimazole 10 mg 67046-1652-03 | Coupler | 30 tablets | — | AB | FDA listed | — |
| Methimazole 10 mg 68788-4063-01 | Preferred | 100 tablets | — | AB | FDA listed | — |
| Methimazole 10 mg 68788-8227-01 | Preferred | 100 tablets | — | AB | FDA listed | — |
| Methimazole 10 mg 70518-1475-00 | REMEDYREPACK | 30 tablets | — | AB | FDA listed | — |
| Methimazole 10 mg 71335-0883-01 | Bryant | 30 tablets | — | AB | FDA listed | — |
| Methimazole 10 mg 71335-2218-01 | Bryant | 30 tablets | — | AB | FDA listed | — |
| Methimazole 10 mg 71335-2349-01 | Bryant | 30 tablets | — | AB | FDA listed | — |
| Methimazole 10 mg 71335-2906-01 | Bryant | 100 tablets | — | AB | FDA listed | — |
| Methimazole 10 mg 71335-3027-01 | Bryant | 180 tablets | — | AB | FDA listed | — |
| Methimazole 10 mg 72162-1803-01 | Bryant | 100 tablets | — | AB | FDA listed | — |
| Methimazole 10 mg 73190-0085-01 | AvKARE | 100 tablets | — | AB | FDA listed | — |
| methimazole 10 mg 76483-0083-00 | SQUARE | 100 tablets | — | AB | FDA listed | — |
| Methimazole 10 mg 82804-0231-30 | Proficient | 30 tablets | — | AB | FDA listed | — |
Where does this data come from?
⏳ Availability & generic status
This product is an FDA-approved generic. Other versions of the same drug are listed under Therapeutic equivalents, least expensive first.
Where does this data come from?
📊 Medicare Part D spend CMS · PART D · 2026 (Q1)
📦 Packaging — all sizes for this product
| Package NDC | Description | Per unit | Per pack | Marketing start | Status |
|---|---|---|---|---|---|
| 62135-0206-01 You're viewing this | 100 TABLET in 1 BOTTLE (62135-206-01) | — | — | 2021-11-04 | Active |
| 62135-0206-18 | 180 TABLET in 1 BOTTLE (62135-206-18) | $0.1246 / ea | $22.43 | 2021-11-04 | Active |
| 62135-0206-30 | 30 TABLET in 1 BOTTLE (62135-206-30) | — | — | 2021-11-04 | Active |
| 62135-0206-90 | 90 TABLET in 1 BOTTLE (62135-206-90) | $0.1246 / ea | $11.22 | 2021-11-04 | Active |
You're viewing one of 4 pack sizes for this product.
Pack size FAQ
What quantity is in NDC 62135-0206-01?
What is the difference between NDC 62135-0206-01 and NDC 62135-0206-30?
What NDC number is used to bill for this package of Methimazole 10 mg Tablet?
Prices are the latest CMS NADAC pharmacy acquisition cost per NDC; per-pack figures are per-unit × pack quantity, shown only when the pack is denominated in the same measure NADAC prices.
🧭 About this NDC listing & data coverage
What data is (and isn’t) available for this NDC — tap to expand
| NDC identity (package / product / labeler codes) | ✓ Available |
| Labeler | ✓ Available |
| Product & package description | ✓ Available |
| Marketing category & status | ✓ Available |
| Active ingredient / dosage form / route | ✓ Available |
| FDA label (SPL via DailyMed) | ✓ Available |
| Package photos | ✓ Available |
| Inactive ingredients (structured) | ✓ Available |
| NADAC pharmacy acquisition price (CMS) | — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey. |
| Orange Book / therapeutic-equivalence data | ✓ Available |
| HCPCS J-code billing crosswalk | — Not published for this NDC Most self-administered / retail products have no J-code — that is normal. |
| Medicaid utilization (CMS SDUD) | — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold. |
Questions about this listing
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📄 Full prescribing information FDA SPL
🎯 Indications and Usage ▾
INDICATIONS AND USAGE Methimazole tablets, USP are indicated: In patients with Graves’ disease with hyperthyroidism or toxic multinodular goiter for whom surgery or radioactive iodine therapy is not an appropriate treatment option. To ameliorate symptoms of hyperthyroidism in preparation for thyroidectomy or radioactive iodine therapy.
⏱️ Dosage and Administration ▾
DOSAGE AND ADMINISTRATION Methimazole tablets, USP are administered orally. The total daily dosage is usually given in 3 divided doses at approximately 8-hour intervals. Adult The initial daily dosage is 15 mg for mild hyperthyroidism, 30 mg to 40 mg for moderately severe hyperthyroidism and 60 mg for severe hyperthyroidism, divided into 3 doses at 8-hour intervals.
The maintenance dosage is 5 mg to 15 mg daily. Pediatric Initially, the daily dosage is 0.4 mg/kg of body weight divided into 3 doses and given at 8-hour intervals. The maintenance dosage is approximately 1/2 of the initial dose.
⛔ Contraindications ▾
CONTRAINDICATIONS Methimazole is contraindicated in the presence of hypersensitivity to the drug or any of the other product components.
⚠️ Warnings ▾
WARNINGS First Trimester Use of Methimazole and Congenital Malformations Methimazole crosses the placental membranes and can cause fetal harm, when administered in the first trimester of pregnancy. Rare instances of congenital defects, including aplasia cutis, craniofacial malformations (facial dysmorphism; choanal atresia) gastrointestinal malformations (esophageal atresia with or without tracheoesophageal fistula) omphalocele and abnormalities of the omphalomesenteric duct have occurred in infants born to mothers who received methimazole in the first trimester of pregnancy.
If methimazole is used during pregnancy or if the patient becomes pregnant while taking this drug, the patient should be warned of the potential hazard to the fetus. Because of the risk for congenital malformations associated with use of methimazole in the first trimester of pregnancy it may be appropriate to use other agents in pregnant women requiring treatment for hyperthyroidism. If methimazole is used, the lowest possible dose to control the maternal disease should be given.
Agranulocytosis Agranulocytosis is potentially a life-threatening adverse reaction of methimazole therapy. Patients should be instructed to immediately report to their physicians any symptoms suggestive of agranulocytosis, such as fever or sore throat. Leukopenia, thrombocytopenia, and aplastic anemia (pancytopenia) may also occur.
The drug should be discontinued in the presence of agranulocytosis or aplastic anemia (pancytopenia), and the patient’s bone marrow indices should be monitored. Liver Toxicity Although there have been reports of hepatotoxicity (including acute liver failure) associated with methimazole, the risk of hepatotoxicity appears to be less with methimazole than with propylthiouracil, especially in the pediatric population. Symptoms suggestive of hepatic dysfunction (anorexia, pruritis, right upper quadrant pain, etc.) should prompt evaluation of liver function (bilirubin, alkaline phosphatase) and hepatocellular integrity (ALT, AST).
Drug treatment should be discontinued promptly in the event of clinically significant evidence of liver abnormality including hepatic transaminase values exceeding 3 times the upper limit of normal. Hypothyroidism Methimazole can cause hypothyroidism necessitating routine monitoring of TSH and free T4 levels with adjustments in dosing to maintain a euthyroid state. Because the drug readily crosses placental membranes, methimazole can cause fetal goiter and cretinism when administered to a pregnant woman.
For this reason, it is important that a sufficient, but not excessive, dose be given during pregnancy (see PRECAUTIONS, Pregnancy ). Vasculitis Cases of vasculitis resulting in severe complications have been reported in patients receiving Methimazole therapy. These cases of vasculitis include: leukocytoclastic cutaneous vasculitis, acute kidney injury and glomerulonephritis, alveolar/pulmonary hemorrhage, CNS vasculitis, and neuropathy.
Most cases were associated with anti-neutrophilic cytoplasmic antibodies (ANCA)-positive vasculitis. In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. If vasculitis is suspected, discontinue therapy and initiate appropriate intervention.
🤒 Adverse Reactions ▾
ADVERSE REACTIONS Major adverse reactions (which occur with much less frequency than the minor adverse reactions) include inhibition of myelopoieses (agranulocytosis, granulocytopenia, thrombocytopenia, and aplastic anemia), drug fever, a lupus-like syndrome, insulin autoimmune syndrome (which can result in hypoglycemic coma), hepatitis (jaundice may persist for several weeks after discontinuation of the drug), periarteritis, and hypoprothrombinemia. Nephritis occurs very rarely. There have been postmarketing case reports of acute pancreatitis.
Minor adverse reactions include skin rash, urticaria, nausea, vomiting, epigastric distress, arthralgia, paresthesia, loss of taste, abnormal loss of hair, myalgia, headache, pruritus, drowsiness, neuritis, edema, vertigo, skin pigmentation, jaundice, sialadenopathy, and lymphadenopathy. There are reports of a vasculitis, often associated with the presence of anti-neutrophilic cytoplasmic antibodies (ANCA), resulting in severe complications (see WARNINGS ).
🆘 Overdosage ▾
OVERDOSAGE Signs and Symptoms Symptoms may include nausea, vomiting, epigastric distress, headache, fever, joint pain, pruritus, and edema. Aplastic anemia (pancytopenia) or agranulocytosis may be manifested in hours to days. Less frequent events are hepatitis, nephrotic syndrome, exfoliative dermatitis, neuropathies, and CNS stimulation or depression.
No information is available on the median lethal dose of the drug or the concentration of methimazole in biologic fluids associated with toxicity and/or death. Treatment To obtain up-to-date information about the treatment of overdose, a good resource is your certified Regional Poison Control Center. In managing overdosage, consider the possibility of multiple drug overdoses, interaction among drugs, and unusual drug kinetics in the patient.
In the event of an overdose, appropriate supportive treatment should be initiated as dictated by the patient’s medical status.
🧬 Clinical Pharmacology ▾
CLINICAL PHARMACOLOGY Methimazole inhibits the synthesis of thyroid hormones and thus is effective in the treatment of hyperthyroidism. The drug does not inactivate existing thyroxine and tri-iodothyronine that are stored in the thyroid or circulating in the blood nor does it interfere with the effectiveness of thyroid hormones given by mouth or by injection. Methimazole is readily absorbed in the gastrointestinal tract, metabolized in the liver, and excreted in the urine.
📦 How Supplied / Storage and Handling ▾
HOW SUPPLIED Methimazole Tablets, USP, for oral administration, are available as 5 mg White, round scored tablet, de-bossed with "CE" over "36" on one side and functional score on the other side and supplied as: NDC 62135-205-30 bottles of 30 NDC 62135-205-90 bottles of 90 NDC 62135-205-01 bottles of 100 NDC 62135-205-18 bottles of 180 NDC 62135-205-05 bottles of 500 10 mg White, round scored tablet, de-bossed with "CE" over "37" on one side and functional score on the other side and supplied as: NDC 62135-206-30 bottles of 30 NDC 62135-206-90 bottles of 90 NDC 62135-206-01 bottles of 100 NDC 62135-206-18 bottles of 180
📦 Storage and Handling ▾
STORAGE Store at 20° to 25°C (68° to 77°F) [see USP Controlled Room Temperature]. Dispense contents in a tight, light-resistant container as defined in the USP with a child-resistant closure, as required. KEEP TIGHTLY CLOSED.
KEEP THIS AND ALL MEDICATION OUT OF THE REACH OF CHILDREN. WARNING – This drug may cause toxic reaction. If such reactions occur, discontinue the drug.
Constant supervision of patient is essential. To report SUSPECTED ADVERSE REACTIONS, contact Chartwell RX, LLC. at 845-232-1683 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. Manufactured for: Chartwell RX, LLC.
Congers, NY 10920 L70634 Rev: 02/2026
📋 Description ▾
DESCRIPTION Methimazole, USP (1-methylimidazole-2-thiol) is a white, crystalline substance that is freely soluble in water. It differs chemically from the drugs of the thiouracil series primarily because it has a 5- instead of a 6-membered ring. Each tablet contains 5 mg or 10 mg (43.8 mcmol or 87.6 mcmol) methimazole USP, an orally administered antithyroid drug.
Each tablet also contains anhydrous lactose, colloidal silicon dioxide, lactose monohydrate, magnesium stearate, pregelatinized starch (corn) and talc. The molecular weight is 114.16, and the molecular formula is C 4 H 6 N 2 S. The structural formula is as follows: image description