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leader acid reducer complete Famotidine, Calcium Carbonate, Magnesium Hydroxide 10 mg; 800 mg; 165 mg Tablet, Chewable, 25-count — NDC 70000-0416-01 package photo

leader acid reducer complete Famotidine, Calcium Carbonate, Magnesium Hydroxide 10 mg; 800 mg; 165 mg Tablet, Chewable, 25-count

by Cardinal Health 110, LLC. dba Leader · 25 TABLET, CHEWABLE in 1 BOTTLE (70000-0416-1)
NDC 70000-0416-01
🏷️ FDA NDC (as labeled) 70000-0416-1 billing pads the package segment with a zero
OTC Generic On market Non-controlled
🗂️ Data synced Sep 10, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

🆔 Identity & classification

FDA NDC (as labeled) 70000-0416-1
Product NDC 70000-0416
11-digit billing NDC 70000041601
NCPDP billing unit EA — each (per item)
RxCUI 283641
UNII 5QZO15J2Z8, H0G9379FGK, NBZ3QY004S
Application # ANDA077355
SPL Set ID 6a492dd2-61f1-4020-bebd-fcc8e5647207
Established class (EPC) Histamine-2 Receptor Antagonist
Mechanism of action Histamine H2 Receptor Antagonists
DEA schedule Non-controlled
Marketing category ANDA
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2018-09-28
Route ORAL
Dosage form TABLET, CHEWABLE
Substance FAMOTIDINE; CALCIUM CARBONATE; MAGNESIUM HYDROXIDE
GPI-14 49993503300520
GPI class Acid Reducer Complete
GCN Seq No 047669
GCN 13069
HICL code 021332
Ingredient (HICL) Famotidine/Ca Carb/Mag Hydrox
HIC1 code Z
Therapeutic class — broad (HIC1) Body As A Whole
HIC2 code Z2
Therapeutic class — intermediate (HIC2) Antihistamines, Antiserotonins, Immunosuppressants
HIC3 code Z2D
Therapeutic class — specific (HIC3) Histamine H2-Receptor Inhibitors
AHFS code 04:92.00.00
AHFS class Other Antihistamines
FDB label name ACID REDUCER COMPLETE TAB CHEW
FDB brand name Acid Reducer Complete
Legend status O — Over-the-counter (OTC) drug or device
Why two NDCs? The FDA registers this code as 70000-0416-1 — a 5-4-1 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the package segment → 70000-0416-01. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

🏷️ RxNorm drug class

This medicine belongs to the Calcium compounds class.

Drug family (ATC) Calcium compounds, Calcium
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

🏭 Manufacturer & labeler

LabelerCardinal Health 110, LLC. dba Leader
Application holderPERRIGO R AND D CO
FDA applicationANDA077355 (ANDA)
Labeler code70000
First marketedSep 2018
Product typeHuman Otc Drug
Portfolio162 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

🩺 Clinical

Label name ACID REDUCER COMPLETE TAB CHEW Ingredient Famotidine/Ca Carb/Mag Hydrox
📗 Our plain-language guide HelloPharmacist
  • This tablet combines two antacids — calcium carbonate and magnesium hydroxide — with famotidine, an acid reducer. The antacids work quickly to neutralize acid that's already in you...
  • What exactly does this tablet do — how is it different from a regular antacid?
  • You do need to chew it completely before swallowing — that's important. Don't swallow the tablet whole. Chewing it first is part of how it works and how it's meant to be used safel...
  • Do I have to chew it, or can I just swallow it?
📖 Read our full Calcium Carbonate / Famotidine / Magnesium Hydroxide guide →

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

🧪 Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

Loading inactive ingredients from the official FDA label in the background. No external source is being called by this page request.
Where does this data come from?
Source: official FDA Structured Product Labeling (SPL) via DailyMed and the openFDA label index. Structured IACT rows and label-wide narrative are kept separate; availability and product-level specificity depend on the submitted label.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

💲 Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer eaPer package
Retail pharmacies payNADAC · weekly $0.261 $6.52 / 25 tablets
Medicaid paysCMS SDUD · 12 mo $0.6599 $16.50 / 25 tablets
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
NADAC price history (per ea) — tap or hover for the price & month
Dec 2021 Sep 2022 Jan 2026 Aug 2026 $0.261 $0.225
▲ Up 16% over the last 21 months.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

🔁 Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Good Sense Dual Action Complete 10 mg/1; 800 mg/1; 165 mg 00113-0032-63 L. 25 tablets $0.261 — Availability likely —
Good Neighbor Pharmacy Dual Action Complete 10 mg/1; 800 mg/1; 165 mg 46122-0345-63 Amerisource 25 tablets $0.261 — Availability likely —
leader acid reducer complete 10 mg/1; 800 mg/1; 165 mgthis 70000-0416-01 Cardinal 25 tablets $0.261 — Availability likely —
leader acid reducer complete 10 mg/1; 800 mg/1; 165 mg 70000-0582-01 Cardinal 50 tablets $0.261 — Availability likely —
foster and thrive acid reducer antacid 10 mg/1; 800 mg/1; 165 mg 70677-1100-01 Strategic 25 tablets $0.261 — Availability likely —
injoy heartburn relief 10 mg/1; 800 mg/1; 165 mg 00113-6023-63 L. 25 tablets — — FDA listed —
Good Sense Dual Action Complete 10 mg/1; 800 mg/1; 165 mg 00113-7050-71 L. 50 tablets — — FDA listed —
Acid Reducer Complete 10 mg/1; 800 mg/1; 165 mg 00363-0511-71 Walgreen 50 tablets — — FDA listed —
Acid Reducer Complete 10 mg/1; 800 mg/1; 165 mg 00363-0713-33 Walgreen 60 tablets — — Discontinued —
Acid Reducer Complete 10 mg/1; 800 mg/1; 165 mg 00363-4036-71 Walgreen 50 tablets — — FDA listed —
acid reducer plus antacid 800 mg/1; 10 mg/1; 165 mg 11822-0223-00 Rite 50 tablets — — Discontinued —
Acid Reducer Plus Antacid 10 mg/1; 165 mg/1; 800 mg 11822-0500-01 Rite 25 tablets — — FDA listed —
Pepcid Complete 10 mg/1; 800 mg/1; 165 mg 16837-0246-25 Kenvue 25 tablets — — FDA listed —
Pepcid Complete 10 mg/1; 800 mg/1; 165 mg 16837-0298-12 Kenvue 100 tablets — — FDA listed —
Pepcid Complete 10 mg/1; 800 mg/1; 165 mg 16837-0891-25 Kenvue 25 tablets — — FDA listed —
Signature Care Acid Reducer Complete 10 mg/1; 800 mg/1; 165 mg 21130-0087-63 Safeway 25 tablets — — FDA listed —
signature care acid reducer complete 10 mg/1; 800 mg/1; 165 mg 21130-0546-63 Safeway 25 tablets — — FDA listed —
Acid Reducer Complete 10 mg/1; 800 mg/1; 165 mg 21130-0614-63 Safeway 25 tablets — — FDA listed —
acid reducer complete 10 mg/1; 800 mg/1; 165 mg 21130-0786-63 Safeway 25 tablets — — FDA listed —
DUAL ACTION Pepcid Complete 10 mg/1; 800 mg/1; 165 mg 29485-6522-02 Lil' 1 tablet — — FDA listed —
Dual Action Complete 10 mg/1; 800 mg/1; 165 mg 30142-0040-63 Kroger 25 tablets — — FDA listed —
Dual Action Complete 10 mg/1; 800 mg/1; 165 mg 30142-0213-71 Kroger 50 tablets — — FDA listed —
topcare dual action complete 10 mg/1; 800 mg/1; 165 mg 36800-0082-63 Topco 25 tablets — — FDA listed —
topcare dual action complete 10 mg/1; 800 mg/1; 165 mg 36800-0616-63 Topco 25 tablets — — FDA listed —
Dual Action Complete 10 mg/1; 800 mg/1; 165 mg 37808-0121-63 H 25 tablets — — FDA listed —
Dual Action Complete 10 mg/1; 800 mg/1; 165 mg 37808-0503-63 H 25 tablets — — FDA listed —
equaline complete dual action 10 mg/1; 800 mg/1; 165 mg 41163-0321-63 United 25 tablets — — FDA listed —
Dual Action Complete 10 mg/1; 800 mg/1; 165 mg 41250-0284-71 Meijer 50 tablets — — FDA listed —
Dual Action Complete 10 mg/1; 800 mg/1; 165 mg 41250-0690-71 Meijer 50 tablets — — FDA listed —
CareOne Acid Reducer Complete 10 mg/1; 165 mg/1; 800 mg 41520-0409-63 American 25 tablets — — FDA listed —
CareOne Acid Reducer Complete 10 mg/1; 800 mg/1; 165 mg 41520-0617-63 American 25 tablets — — FDA listed —
complete dual action 10 mg/1; 800 mg/1; 165 mg 42507-0321-50 HyVee 50 tablets — — FDA listed —
Equate Acid Reducer Complete 10 mg/1; 800 mg/1; 165 mg 49035-0321-63 Wal-Mart 25 tablets — — FDA listed —
Equate Acid Reducer Complete 10 mg/1; 800 mg/1; 165 mg 49035-0546-71 Wal-Mart 50 tablets — — FDA listed —
Pepcid Complete 800 mg/1; 165 mg/1; 10 mg 50269-0016-01 JC 1 tablet — — FDA listed —
Complete Acid Reducer 10 mg/1; 800 mg/1; 165 mg 51316-0588-63 CVS 25 tablets — — FDA listed —
Pepcid Complete 10 mg/1; 800 mg/1; 165 mg 53209-4001-02 Morning 1 tablet — — FDA listed —
DG Health acid reducer complete 10 mg/1; 800 mg/1; 165 mg 55910-0808-63 Dolgencorp, 25 tablets — — FDA listed —
dual action complete 10 mg/1; 800 mg/1; 165 mg 56062-0263-63 Publix 25 tablets — — FDA listed —
Acid Reducer Plus Antacid 10 mg/1; 165 mg/1; 800 mg 59779-0738-63 CVS 25 tablets — — FDA listed —
Acid Reducer Plus Antacid 10 mg/1; 800 mg/1; 165 mg 59779-0862-63 CVS 25 tablets — — FDA listed —
Pepcid Complete 165 mg/1; 10 mg/1; 800 mg 66715-6422-07 Lil' 1 tablet — — FDA listed —
Pepcid Complete, TRAVEL BASIX 165 mg/1; 10 mg/1; 800 mg 66715-6522-02 Lil' 1 tablet — — FDA listed —
Pepcid Complete, TRAVEL BASIX 165 mg/1; 10 mg/1; 800 mg 66715-7822-02 Lil' 1 tablet — — FDA listed —
Pepcid Complete 165 mg/1; 10 mg/1; 800 mg 66715-9822-02 Lil' 1 tablet — — FDA listed —
Pepcid Complete 10 mg/1; 800 mg/1; 165 mg 67751-0202-01 Navajo 1 tablet — — FDA listed —
Pepcid Complete 10 mg/1; 800 mg/1; 165 mg 70264-0034-01 R 50 tablets — — FDA listed —
Basic Care Dual Action Complete 10 mg/1; 800 mg/1; 165 mg 72288-0321-71 Amazon.com 50 tablets — — FDA listed —
Pepcid Complete 10 mg/1; 800 mg/1; 165 mg 73097-0017-25 Savings 1 tablet — — FDA listed —
Up And Up Dual Action Acid Reducer Antacid 10 mg/1; 800 mg/1; 165 mg 82442-0321-71 Target 50 tablets — — FDA listed —
Up and Up Dual Action Acid Reducer and Antacid 10 mg/1; 800 mg/1; 165 mg 82442-0546-71 Target 50 tablets — — FDA listed —
About this product: this is a generic version of the medicine. FDA equivalence ratings are shown when available, and other versions are listed above, least expensive first.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

⏳ Availability & generic status

🏛️
2018
On the market since
Sep 2018
📍
2026
Currently FDA-listed
8 years listed
🔓
·
Generic on the market
this product is a generic
✅This is a generic drug

This product is an FDA-approved generic. Other versions of the same drug are listed under Therapeutic equivalents, least expensive first.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

🗺️ Medicaid utilization & spend

📍 This exact package only: Medicaid data is reported per full 11-digit NDC — labeler, product and pack size — so every number here is for 70000-0416-01, not the drug overall. Other pack sizes report separately.
💊 Pharmacy benefit only: These are Medicaid outpatient pharmacy claims, billed by NDC. They exclude the medical benefit — clinic- or hospital-administered drugs billed under HCPCS J-codes — so drugs used mostly that way (e.g. Avastin, Lucentis, Keytruda) can look low or missing here. That’s expected, not an error.
📅 Q1 2025 – Q4 2025 · 4 quarters of data
ⓘ The newest quarter is usually incomplete when first published; states restate recent quarters in later CMS releases, so the latest figures typically revise upward. State coverage-policy changes can also shift quarter-to-quarter totals.
Prescriptions last 4 qtrs
86
Units reimbursed last 4 qtrs
2.7K
Gross reimbursed last 4 qtrs
$1.8K
Avg / prescription
$20.43
Avg / unit
$0.6599
Latest quarter Q4 2025
29Rx
Medicaid pays / ea
$0.6599
gross reimbursed
vs
NADAC / ea
$0.2607
acquisition cost
=
Spread
+$0.3992
+153% vs cost
What Medicaid paid per ea (before rebates; includes the pharmacy’s dispensing fee) compared with NADAC — the average price pharmacies pay to buy the drug. A positive spread means Medicaid reimbursed more than the purchase price, before manufacturer rebates.
Fee-for-service vs managed care ⓘ
100% FFS
Fee-for-service · 86 Rx Managed care · 0 Rx
State Medicaid map
Alaska: no data reported AK Maine: no data reported ME Washington: no data reported WA Idaho: no data reported ID Montana: no data reported MT North Dakota: no data reported ND Minnesota: no data reported MN Wisconsin: no data reported WI Michigan: no data reported MI New York: no data reported NY Vermont: no data reported VT New Hampshire: no data reported NH Oregon: no data reported OR Nevada: no data reported NV Wyoming: no data reported WY South Dakota: no data reported SD Iowa: no data reported IA Illinois: no data reported IL Indiana: no data reported IN Ohio: no data reported OH Pennsylvania: no data reported PA New Jersey: no data reported NJ Massachusetts: no data reported MA California: 2,388 units · 6.1 per 100k residents CA Utah: no data reported UT Colorado: no data reported CO Nebraska: no data reported NE Missouri: no data reported MO Kentucky: no data reported KY West Virginia: no data reported WV Virginia: no data reported VA Maryland: no data reported MD Connecticut: no data reported CT Rhode Island: no data reported RI Arizona: no data reported AZ New Mexico: no data reported NM Kansas: no data reported KS Arkansas: 275 units · 9.0 per 100k residents AR Tennessee: no data reported TN North Carolina: no data reported NC South Carolina: no data reported SC Delaware: no data reported DE Oklahoma: no data reported OK Louisiana: no data reported LA Mississippi: no data reported MS Alabama: no data reported AL Georgia: no data reported GA D.C.: no data reported DC Hawaii: no data reported HI Texas: no data reported TX Florida: no data reported FL
Units reimbursed · per 100k residents
6.19.0
gray = no data reported ⓘ
Colors are per 100,000 residents, so big states don’t automatically dominate. Tap or hover a state for its actual totals.
Tap or hover a state
…for its Medicaid breakdown
🏆 Top states by units · per 100k residents
1 Arkansas 9.0 /100k
2 California 6.1 /100k
National units — by quarter
💵 About the dollar figures: “reimbursed” is what Medicaid paid pharmacies before confidential manufacturer rebates, so the program’s real net cost is lower than these numbers. Fee-for-service and managed-care claims are combined unless split above. Source: CMS State Drug Utilization Data; per-100k rates use 2023 Census population estimates.

📦 Packaging — all sizes for this product

Package NDCDescription Marketing startStatus
70000-0416-01 You're viewing this 25 TABLET, CHEWABLE in 1 BOTTLE (70000-0416-1) 2018-09-28 Active

📄 FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 📦 Storage and Handling 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose
🎯 Indications and Usage 10 words ▾

Use relieves heartburn associated with acid indigestion and sour stomach

⏱️ Dosage and Administration 46 words ▾

Directions • adults and children 12 years and over: • do not swallow tablet whole: chew completely • to relieve symptoms, chew 1 tablet before swallowing • do not use more than 2 chewable tablets in 24 hours • children under 12 years: ask a doctor

⚠️ Warnings 205 words ▾

Warnings Allergy alert: Do not use if you are allergic to famotidine or other acid reducers Do not use • if you have trouble or pain swallowing food, vomiting with blood, or bloody or black stools. These may be signs of a serious condition. See your doctor. • with other acid reducers Ask a doctor before use if you have • had heartburn over 3 months.

This may be a sign of a more serious condition. • heartburn with lightheadedness, sweating, or dizziness • chest pain or shoulder pain with shortness of breath; sweating; pain spreading to arms, neck or shoulders; or lightheadedness • frequent chest pain • frequent wheezing, particularly with heartburn • unexplained weight loss • nausea or vomiting • stomach pain • kidney disease Ask a doctor or pharmacist before use if you are taking a prescription drug. Antacids may interact with certain prescription drugs. Stop use and ask a doctor if • your heartburn continues or worsens • you need to take this product for more than 14 days If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222)

📦 Storage and Handling 46 words ▾

Other information • each tablet contains: calcium 330 mg; magnesium 80 mg • Phenylketonurics: Contains Phenylalanine 2 mg per tablet • read the directions and warnings before use • read the bottle label. It contains important information. • store at 20-25°C (68-77°F) • protect from moisture

🧪 Active Ingredient 17 words ▾

Active ingredients (in each chewable tablet) Famotidine 10 mg Calcium carbonate 800 mg Magnesium hydroxide 165 mg

🧪 Inactive Ingredients 30 words ▾

Inactive ingredients anhydrous lactose, aspartame, dextrates, ferric oxide, glyceryl monostearate, lactose monohydrate, magnesium stearate, microcrystalline cellulose, natural peppermint flavor, polyacrylate dispersion, polysorbate 80, povidone, pregelatinized starch, sodium starch glycolate, talc

🎯 Purpose 4 words ▾

Purposes Acid reducer Antacid

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗
← 70000-0415-01 · Cardinal 70000-0417-01 · Cardinal →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.