Home › NDC Lookup › Ingredients › Aspirin › 72189-0187-60
⚪no package photo
in the FDA label

ASPIRIN 325 mg Tablet, 60-count

by DIRECT RX · 60 TABLET in 1 BOTTLE (72189-187-60)
NDC 72189-0187-60
🏷️ FDA NDC (as labeled) 72189-187-60 billing pads the product segment with a zero
OTC Discontinued Non-controlled ⚠ Discontinued by firm
🗂️ Data synced Nov 29, 2022 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

⚠️
Excluded from the active FDA NDC Directory. The labeler reported this product as discontinued, so it is excluded from the active NDC Directory. The listing was last certified through Oct 2023. A label may still appear on DailyMed, but the NDC is no longer in the current FDA NDC Directory. Search the FDA NDC Directory ↗

🆔 Identity & classification

FDA NDC (as labeled) 72189-187-60
Product NDC 72189-187
11-digit billing NDC 72189018760
NCPDP billing unit EA — each (per item)
Application # part343
Established class (EPC) Anti-Inflammatory Agents, Non-Steroidal [CS], Cyclooxygenase Inhibitors [MoA], Decreased Platelet Aggregation [PE], Decreased Prostaglandin Production [PE], Nonsteroidal Anti-inflammatory Drug [EPC], Platelet Aggregation Inhibitor
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH NOT FINAL
Marketing status Discontinued
FDA listing status Discontinued by firm (certified through Oct 2023)
Route ORAL
Dosage form TABLET
Substance ASPIRIN
Why two NDCs? The FDA registers this code as 72189-187-60 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 72189-0187-60. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

🏭 Manufacturer & labeler

LabelerDIRECT RX
FDA applicationpart343 (OTC MONOGRAPH NOT FINAL)
Labeler code72189
Product typeHuman Otc Drug
Portfolio204 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

🩺 Clinical

📖 What it is MedlinePlus · NLM

Aspirin is used to: reduce fever relieve mild to moderate pain and inflammation prevent heart attacks, strokes or mini-strokes reduce the risk of death in people who are experiencing or who have had a heart attack Aspirin is in a group of medications called salicylates. It works by blocking natural substances that cause fever, pain, swelling, and blood clots. Aspirin is also available in combination with other medications such as pain relievers and cough and cold medications. This monograph only includes information about the use of aspirin alone. If you are taking a combination product,...

Read the full MedlinePlus article ↗
📗 Our plain-language guide HelloPharmacist
  • Aspirin is a pain reliever and fever reducer. You can use it for everyday aches like headaches, backaches, muscle pain, toothaches, menstrual cramps, and minor arthritis pain. It a...
  • Most aspirin products are not recommended for children under 12. More importantly, children and teenagers who have chickenpox or a flu-like illness should never take aspirin becaus...
  • Aspirin can irritate the stomach lining, so taking it with food or a full glass of water can help reduce that irritation. All aspirin products direct you to drink a full glass of w...
  • Is it okay to take aspirin on an empty stomach?
📖 Read our full Aspirin guide →
3
Nutrient depletion considerations

Aspirin may be associated with lower levels of 3 nutrients — worth a chat with your pharmacist, not a cause for alarm.

🧪 Full Aspirin nutrient depletion report →
An association is not a deficiency. Educational only — don't start or stop anything without professional guidance.
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

🧪 Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

We could not link this NDC to a current FDA Structured Product Label. An inactive-ingredient list is therefore not available from this source.
Where does this data come from?
Source: official FDA Structured Product Labeling (SPL) via DailyMed and the openFDA label index. Structured IACT rows and label-wide narrative are kept separate; availability and product-level specificity depend on the submitted label.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

💲 Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer eachPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

🔁 Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Aspirin 325 mg 00536-1054-05 Rugby 500 tablets $0.011 — Discontinued —
Aspirin 325 mg 63868-0352-03 CHAIN 300 tablets $0.011 — Discontinued —
Aspirin 325 mg 46122-0691-78 Amerisource 100 tablets $0.016 — Availability likely —
McKesson Aspirin 325 mg 68599-1311-03 McKesson 2 tablets $0.016 — Availability likely —
Aspirin 325 mg 70000-0253-02 Cardinal 100 tablets $0.016 — Availability likely —
Aspirin 325 mg 70677-1189-01 Strategic 100 tablets $0.016 — Availability likely —
Aspirin 325 mg 83324-0066-01 Chain 100 tablets $0.016 — Availability likely —
Aspirin 325 mg 83324-0205-01 CHAIN 100 tablets $0.016 — Availability likely —
Tri-Buffered Aspirin 325 mg 00904-2015-59 Major 100 tablets $0.021 — Discontinued —
Buffered Aspirin 325 mg 70000-0147-01 Cardinal 130 tablets $0.021 — Availability likely —
Bayer Genuine Aspirin 325 mg 00280-2000-01 Bayer 300 tablets — — FDA listed —
Aspirin Regular Strength 325 mg 00363-0157-14 Walgreen 500 tablets — — FDA listed —
Physicians Care Aspirin 325 mg 00924-0105-00 Acme 2 tablets — — FDA listed —
Bayer Genuine Aspirin 325 mg 00924-6020-02 Acme 100 tablets — — FDA listed —
Regular strength aspirin 325 mg 11673-0188-53 TARGET 500 tablets — — FDA listed —
Pain Relief Aspirin 325 mg 11822-0157-02 Rite 100 tablets — — FDA listed —
Aspirin 325 mg 17714-0010-01 Advance 100 tablets — — FDA listed —
Aspirin 325 mg 21130-0758-53 BETTER 500 tablets — — FDA listed —
Aspirin 325 mg 21130-0957-14 Better 500 tablets — — Discontinued —
Aspirin 325 mg 36800-0157-12 Topco 100 tablets — — FDA listed —
Aspirin 325 mg 37808-0157-12 H 100 tablets — — Discontinued —
Aspirin 325 mg 37835-0577-01 Bi-Mart 100 tablets — — FDA listed —
Aspirin 325 mg 37835-0738-02 Bi-Mart 100 tablets — — FDA listed —
Aspirin 325 mg 41163-0157-12 United 100 tablets — — FDA listed —
Regular Strength Aspirin 325 mg 41226-0011-32 Kroger 300 tablets — — FDA listed —
Aspirin Regular Strength 325 mg 41250-0118-11 Meijer 100 tablets — — Discontinued —
Aspirin Regular Strength 325 mg 41520-0157-78 FOODHOLD 100 tablets — — FDA listed —
ASPIRIN 325 mg 42507-0018-11 HYVEE 100 tablets — — FDA listed —
Bayer Genuine Aspirin 325 mg 47682-0456-47 Unifirst 2 tablets — — FDA listed —
Medique at Home Aspirin 325 mg 47682-0533-33 Unifirst 2 tablets — — FDA listed —
Medique Products Aspirin 325 mg 47682-0616-13 Unifirst 2 tablets — — FDA listed —
Medi-First Aspirin 325 mg 47682-0617-13 Unifirst 2 tablets — — FDA listed —
Medi-First Plus Aspirin 325 mg 47682-0618-33 Unifirst 2 tablets — — FDA listed —
Aspirin 325 mg 49035-0157-06 Wal-Mart 200 tablets — — Discontinued —
Unishield Aspirin 325 mg 49314-1163-03 Unishield 2 tablets — — FDA listed —
Aspirin 325 mg 49483-0011-00 TIME 100000 tablets — — FDA listed —
Bufferin Regular Strength Pain Relief 325 mg 50066-0610-13 Genomma 130 tablets — — FDA listed —
Aspirin 325 mg 50090-6195-08 A-S 100 tablets — — FDA listed —
Bayer Genuine Aspirin 325 mg 50269-0005-06 JC 24 tablets — — FDA listed —
Bayer Genuine Aspirin 325 mg 50269-0006-06 JC 12 tablets — — FDA listed —
Aspirin 325 mg 50332-0139-03 HART 50 tablets — — FDA listed —
Aspirin 325 mg 50804-0157-12 Geiss, 100 tablets — — FDA listed —
Aspirin 325 mg 50844-0157-12 L.N.K. 100 tablets — — FDA listed —
Coated Aspirin 325 mg 50844-0254-12 L.N.K. 100 tablets — — FDA listed —
Aspirn 325 mg 51662-1583-01 HF 2 tablets — — FDA listed —
Aspirin 325 mg 53185-0249-12 Athlete's 100 tablets — — FDA listed —
Aspirin 325 mg 53943-0157-12 Discount 100 tablets — — FDA listed —
Geritrex Aspirin 325 mg 54162-0940-90 Geritrex 1000 tablets — — FDA listed —
Aspirin 325 mg 54738-0541-01 Richmond 100 tablets — — FDA listed —
Aspirin 325 mg 55301-0157-12 ARMY 100 tablets — — FDA listed —
Rapidol Aspirin 325 mg 55758-0363-60 Pharmadel 60 tablets — — FDA listed —
Aspirin 325 mg 55910-0249-29 DOLGENCORP, 150 tablets — — FDA listed —
aspirin 325 mg 56062-0118-11 PUBLIX 100 tablets — — FDA listed —
Aspirin 325 mg 57243-0157-12 Salado 100 tablets — — FDA listed —
Aspirin 325 mg 57344-0018-11 AAA 100 tablets — — FDA listed —
Aspirin 325 mg 57896-0901-01 Geri-Care 100 tablets — — FDA listed —
Aspirin 325 mg 58228-0071-01 PROSTAT 20000 tablets — — FDA listed —
Travel Savvy Aspirin 325 mg 59961-0616-15 Bellegrove 2 tablets — — FDA listed —
Aspirin 325 mg 60760-0930-24 St. 24 tablets — — FDA listed —
Direct Safety Aspirin 325 mg 61245-0616-13 Direct 2 tablets — — FDA listed —
Aspirin 325 mg 63941-0118-19 VALU 300 tablets — — FDA listed —
Aspirin NSAID 325 mg 63941-0157-12 Valu 100 tablets — — FDA listed —
Aspirin 325 mg 63941-0249-12 Valu 100 tablets — — Discontinued —
Circle K Aspirin 325 325 mg 66715-5504-04 Lil 100 tablets — — FDA listed —
BAYER Aspirin Original, TRAVEL BASIX 325 mg 66715-6426-02 Lil' 4 tablets — — FDA listed —
BAYER Aspirin Original, CVP HEALTH 325 mg 66715-6526-02 Lil' 4 tablets — — FDA listed —
Lil Drug Store Aspirin 325 325 mg 66715-6840-06 Lil 100 tablets — — FDA listed —
Bayer 325 mg 66715-9726-02 Lil' 4 tablets — — FDA listed —
Bayer Genuine Aspirin 325 mg 67751-0129-01 Navajo 2 tablets — — FDA listed —
Aspirin 325 mg 68788-8256-01 Preferred 100 tablets — — FDA listed —
Aspirin 325 mg 68998-0018-11 Marc 100 tablets — — FDA listed —
Aspirin 325 mg 69168-0312-01 Allegiant 100 tablets — — FDA listed —
Aspirin 325 mg 69396-0158-01 Trifecta 100 tablets — — FDA listed —
Aspirin 325 mg 69396-0173-01 Trifecta 1000 tablets — — FDA listed —
Extra Strength Aspirin 325 mg 69517-0002-05 HealthLife 500 tablets — — Discontinued —
Aspirin 325 mg 69732-0008-01 Hi-Tech 200 tablets — — FDA listed —
ULINE Aspirin 325 mg 69790-0616-33 ULINE 2 tablets — — FDA listed —
Bayer Genuine Aspirin 325 mg 70264-0013-01 R 100 tablets — — FDA listed —
Aspirin Packs 325 mg 70385-2006-02 Sina 2 tablets — — FDA listed —
Tri-Buffered Aspirin 325 mg 71205-0517-30 Proficient 30 tablets — — FDA listed —
Aspirin 325 mg 71679-0302-00 Health 28500 tablets — — FDA listed —
Aspirin 325 mg 72036-0018-11 HARRIS 100 tablets — — FDA listed —
Aspirin Regular Strength 325 mg 72476-0018-11 RETAIL 100 tablets — — FDA listed —
Aspirin 325 mg 72789-0574-25 PD-Rx 25 tablets — — FDA listed —
Aspirin Regular Strength 325 mg 73057-0365-08 Ulai 100 tablets — — FDA listed —
Thompson Aspirin 325 mg 73408-0618-33 Thompson 2 tablets — — FDA listed —
Aspirin 50 CT 325 mg 73598-1112-01 JHK 50 tablets — — FDA listed —
Aspirin 325 mg 77333-0050-20 Gendose 1 tablet — — FDA listed —
Aspirin 325 mg 79481-1570-01 Meijer 100 tablets — — FDA listed —
Aspirin 325 mg 82804-0167-60 Proficient 60 tablets — — FDA listed —
Aspirin 325 mg 82804-0237-04 Proficient 4 tablets — — FDA listed —
Extra Strength Aspirin 325 mg 83586-0115-01 HHH 100 tablets — — FDA listed —
Aspirin 325 mg 85111-0901-10 RMT 1000 tablets — — FDA listed —
Bayer Genuine Aspirin 325 mg 85237-1828-01 Select 1 tablet — — FDA listed —
Medique at Home Aspirin 325 mg 85766-0125-01 Sportpharm 2 tablets — — FDA listed —
Aspirin 325 mgthis 72189-0187-60 DIRECT 60 tablets — — Discontinued —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

⏳ Availability & generic status

📍
2026
Currently FDA-listed
listed with the FDA
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

📦 Packaging — all sizes for this product

Package NDCDescription Marketing startStatus
72189-0187-60 You're viewing this 60 TABLET in 1 BOTTLE (72189-187-60) 2021-06-04 Discontinued by firm

🧭 About this NDC listing & data coverage

Over-the-counter (OTC) product No longer marketed (per FDA listing data)
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) — Not published for this NDC No structured label is linked to this listing in DailyMed/openFDA.
Package photos — Not published for this NDC The FDA label for this product carries no photos.
Inactive ingredients (structured) — Not published for this NDC The labeler did not submit a structured excipient list, or no SPL is available.
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Not Final". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Why is there no full label on this page?
No structured FDA label (SPL) is currently linked to this NDC in DailyMed/openFDA. That can happen with older listings, certain OTC and repackaged products, and recently updated listings whose label has not yet propagated. The listing itself is still valid — this page shows everything the public feeds provide for this package.
What does the discontinued status mean for this NDC?
The labeler reported a marketing end date (or the listing was delisted), so this specific package is no longer actively marketed. Remaining stock may still be dispensed for a time, and the NDC stays valid for historical records and claims — but data feeds (pricing, labeling) typically stop updating for it. Other package sizes or other manufacturers' versions of the same medication may still be marketed — see the equivalents section where available.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The FDA registers it as 72189-187-60, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 72189-0187-60, written without dashes as 72189018760. The Identity section at the top of this page lists every form of this code.
What do the three segments of this NDC mean?
In 72189-0187-60, the first segment (72189) is the labeler code FDA assigned to DIRECT RX; the middle segment (0187) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (60) identifies this exact package size and type. Together they name one specific package of one specific product.
Who lists this product with the FDA?
DIRECT RX is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.

📄 FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
📄 FDA label
📄 FDA label 19 words ▾

No FDA label is on file for this product yet. Labels load from openFDA / DailyMed and refresh weekly.

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA.
← 72189-0186-32 · DIRECT 72189-0189-30 · DIRECT →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.