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Diphenhydramine hydrochloride 50 MG Oral Capsule — RxCUI 1020477

RxNorm drug concept · Semantic clinical drug
RxCUI 1020477 Semantic clinical drug · SCD ● Current RxNorm concept 106 FDA products 183 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1020477
Official nameDiphenhydramine hydrochloride 50 MG Oral Capsule
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known asdiphenhydramine HCl 50 MG Oral Capsule
FDA products mapped106
Package NDCs mapped183
Reported Medicaid activity (SDUD)164,999 prescriptions · 43 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Diphenhydramine Topical: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • You can use it for temporary relief of pain and itching from everyday skin problems — things like insect bites, minor burns, minor cuts and scrapes, and general skin irritations. I...
  • What can I actually use this cream or spray for?
  • You can apply it up to 3 to 4 times a day, but no more than that. More frequent use isn't going to help more — and the label is clear that you shouldn't exceed that limit. For kids...
  • This is really important — do not use this topical product at the same time as any other product that contains diphenhydramine, even a pill or capsule. That includes allergy medici...
📖 Read our full Diphenhydramine Topical guide →

🕸️ Concept Web — How Diphenhydramine hydrochloride 50 MG Oral Capsule Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Diphenhydramine hydrochloride 50 MG Oral Capsule RxCUI 1020477

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 2

    The active substance itself — no strength, form, or brand attached yet.

    • Diphenhydramine 3498
    • Diphenhydramine hydrochloride 1362
  2. Brand names 8

    The same medicine's trade names. A brand name alone says nothing about strength or form.

    • Banophen 215558
    • Benadryl 203457
    • Compoz 1085965
    • Nytol 1092413
    • Sleep-Eze 1092744
    • Sleepinal 219956
    • Unisom Sleep 1093099
    • Wal-Som Maximum Strength 1090453
  3. Dose forms 41

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Diphenhydramine Oral Capsule 371891
    • Diphenhydramine hydrochloride Oral Capsule 2647158
    • Diphenhydramine Oral Product 1158449
    • Diphenhydramine Pill 1158450
    • Diphenhydramine hydrochloride Oral Product 2659104
    • Diphenhydramine hydrochloride Pill 2659100
    • Diphenhydramine Oral Capsule [Banophen] 366259
    • Diphenhydramine Oral Capsule [Benadryl] 366257
    • +33 more in this family
  4. Clinical & branded drugs 17

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

Showing up to 8 concepts per family — 26 of 68 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

  • Diphenhydramine hydrochloride 50 MG SCDC · 1020476
  • Diphenhydramine Oral Capsule SCDF · 371891
  • Diphenhydramine hydrochloride Oral Capsule SCDFP · 2647158
  • Diphenhydramine Oral Product SCDG · 1158449
  • Diphenhydramine Pill SCDG · 1158450
  • Diphenhydramine hydrochloride Oral Product SCDGP · 2659104
  • Diphenhydramine hydrochloride Pill SCDGP · 2659100

Brand-Name Concepts

📦 FDA Products & Package NDCs

106 products · 183 package NDCs
183 package NDCs map to RxCUI 1020477 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
00363-0816-10 1 BOTTLE, PLASTIC in 1 BOX (0363-0816-10) / 100 CAPSULE in... Wal Som Nighttime Sleep Aid Walgreens 2019-10-30
00363-0816-16 160 CAPSULE in 1 BOTTLE, PLASTIC (0363-0816-16) Wal Som Nighttime Sleep Aid Walgreens 2019-10-30
00363-0816-32 1 BOTTLE, PLASTIC in 1 BOX (0363-0816-32) / 32 CAPSULE in 1... Wal Som Nighttime Sleep Aid Walgreens 2019-10-30
00363-0816-40 1 BOTTLE, PLASTIC in 1 BOX (0363-0816-40) / 40 CAPSULE in 1... Wal Som Nighttime Sleep Aid Walgreens 2019-10-30
00363-0816-60 1 BOTTLE, PLASTIC in 1 BOX (0363-0816-60) / 60 CAPSULE in 1... Wal Som Nighttime Sleep Aid Walgreens 2019-10-30
00363-0860-16 160 CAPSULE in 1 BOTTLE, PLASTIC (0363-0860-16) Wal Som Nighttime Sleep Aid Nighttime Walgreens 2019-10-30
00363-0860-32 1 BOTTLE, PLASTIC in 1 BOX (0363-0860-32) / 32 CAPSULE in 1... Wal Som Nighttime Sleep Aid Nighttime Walgreens 2019-10-30
00363-0860-60 1 BOTTLE, PLASTIC in 1 BOX (0363-0860-60) / 60 CAPSULE in 1... Wal Som Nighttime Sleep Aid Nighttime Walgreens 2019-10-30
00363-6123-20 1 BOTTLE in 1 CARTON (0363-6123-20) / 100 CAPSULE, LIQUID F... Allergy Relief WALGREEN COMPANY 2025-05-22
00904-2056-61 10 BLISTER PACK in 1 BOX (0904-2056-61) / 10 CAPSULE in 1 B... Diphenhydramine Hydrochloride Major Pharmaceuticals 2009-01-02
00904-5307-60 100 CAPSULE in 1 BOTTLE (0904-5307-60) Banophen Major Pharmaceuticals 2009-11-02
00904-5307-80 1000 CAPSULE in 1 BOTTLE (0904-5307-80) Banophen Major Pharmaceuticals 2009-11-02
11673-0360-32 1 BOTTLE, PLASTIC in 1 BOX (11673-360-32) / 32 CAPSULE in 1... Sleep Aid TARGET Corporation 2023-08-01
11673-0360-60 1 BOTTLE, PLASTIC in 1 BOX (11673-360-60) / 60 CAPSULE in 1... Sleep Aid TARGET Corporation 2023-08-01
16103-0347-08 100 CAPSULE in 1 BOTTLE, PLASTIC (16103-347-08) PHARBEDRYL Pharbest Pharmaceuticals, Inc. 2006-10-11
16103-0347-11 1000 CAPSULE in 1 BOTTLE, PLASTIC (16103-347-11) PHARBEDRYL Pharbest Pharmaceuticals, Inc. 2006-10-11
17714-0021-01 100 CAPSULE in 1 BOTTLE (17714-021-01) Diphenhydramine Hydrochloride Advance Pharmaceutical Inc. 1989-10-05
17714-0021-10 1000 CAPSULE in 1 BOTTLE (17714-021-10) Diphenhydramine Hydrochloride Advance Pharmaceutical Inc. 1989-10-05
21130-0052-32 1 BOTTLE in 1 CARTON (21130-052-32) / 32 CAPSULE, LIQUID FI... Sleep Aid Better Living Brands LLC 2023-11-08
21130-0052-96 96 CAPSULE, LIQUID FILLED in 1 BOTTLE (21130-052-96) Sleep Aid Better Living Brands LLC 2023-11-08
21130-0816-32 1 BOTTLE, PLASTIC in 1 BOX (21130-816-32) / 32 CAPSULE in 1... Sleep Aid Safeway, Inc. 2019-11-29
21130-0816-96 96 CAPSULE in 1 BOTTLE, PLASTIC (21130-816-96) Sleep Aid Safeway, Inc. 2019-11-29
21130-0860-32 1 BOTTLE, PLASTIC in 1 BOX (21130-860-32) / 32 CAPSULE in 1... Sleep Aid Safeway, Inc. 2019-11-29
21130-0860-96 96 CAPSULE in 1 BOTTLE, PLASTIC (21130-860-96) Sleep Aid Safeway, Inc. 2019-11-29
24689-0154-01 100 CAPSULE, LIQUID FILLED in 1 BOTTLE (24689-154-01) SleepAid (Diphenhydramine HCL) APNAR PHARMA LP 2023-05-04
30142-0558-64 1 BOTTLE in 1 CARTON (30142-558-64) / 64 CAPSULE, LIQUID FI... Kroger Nighttime Sleep-Aid THE KROGER CO 2021-04-15
30142-0681-18 1 BOTTLE in 1 CARTON (30142-681-18) / 64 CAPSULE, LIQUID FI... Nighttime Sleep-Aid KROGER COMPANY 2024-03-20
30142-0715-32 1 BOTTLE, PLASTIC in 1 BOX (30142-715-32) / 32 CAPSULE in 1... Sleep Aid The Kroger Co. 2021-03-26
30142-0715-92 2 BOTTLE, PLASTIC in 1 PACKAGE (30142-715-92) / 96 CAPSULE... Sleep Aid The Kroger Co. 2021-03-26
30142-0715-96 96 CAPSULE in 1 BOTTLE, PLASTIC (30142-715-96) Sleep Aid The Kroger Co. 2021-03-26
35916-0438-01 100 CAPSULE, LIQUID FILLED in 1 BOTTLE (35916-0438-1) DIPHENHYDRAMINE HYDROCHLORIDE SOFTGEL HEALTHCARE PRIVATE LIMITED 2024-01-11
35916-0438-03 1000 CAPSULE, LIQUID FILLED in 1 BAG (35916-0438-3) DIPHENHYDRAMINE HYDROCHLORIDE SOFTGEL HEALTHCARE PRIVATE LIMITED 2025-03-01
35916-0470-01 1000 CAPSULE, LIQUID FILLED in 1 BAG (35916-0470-1) DIPHENHYDRAMINE HYDROCHLORIDE Softgel Healthcare Pvt Ltd 2025-04-22
35916-0472-01 1000 CAPSULE, LIQUID FILLED in 1 BAG (35916-0472-1) Diphenhydramine hydrochloride Softgel Healthcare Pvt Ltd 2025-04-08
35916-0472-02 2 POUCH in 1 BOX (35916-0472-2) / 3000 CAPSULE, LIQUID FILL... Diphenhydramine hydrochloride Softgel Healthcare Pvt Ltd 2025-07-16
35916-0472-03 2 BAG in 1 BOX (35916-0472-3) / 1500 CAPSULE, LIQUID FILLED... Diphenhydramine hydrochloride Softgel Healthcare Pvt Ltd 2026-01-24
36800-0116-32 1 BOTTLE, PLASTIC in 1 BOX (36800-116-32) / 32 CAPSULE in 1... Nighttime Sleep Aid TOP CARE (Topco Associates LLC) 2020-01-31
36800-0116-64 1 BOTTLE, PLASTIC in 1 BOX (36800-116-64) / 64 CAPSULE in 1... Nighttime Sleep Aid TOP CARE (Topco Associates LLC) 2020-01-31
37808-0860-12 120 CAPSULE in 1 BOTTLE, PLASTIC (37808-860-12) Sleep Aid Maximum Strength H E B 2020-05-29
37808-0860-32 1 BOTTLE, PLASTIC in 1 BOX (37808-860-32) / 32 CAPSULE in 1... Sleep Aid Maximum Strength H E B 2020-05-29
41163-0860-32 1 BOTTLE, PLASTIC in 1 BOX (41163-860-32) / 32 CAPSULE in 1... Sleep Aid Nighttime United Natural Foods, Inc. dba UNFI 2019-12-27
41163-0860-96 96 CAPSULE in 1 BOTTLE, PLASTIC (41163-860-96) Sleep Aid Nighttime United Natural Foods, Inc. dba UNFI 2019-12-27
41167-0061-00 1 BLISTER PACK in 1 CARTON (41167-0061-0) / 8 CAPSULE, LIQU... Unisom SleepGels Nighttime Sleep-Aid Chattem, Inc. 2007-01-01
41167-0061-01 2 BLISTER PACK in 1 CARTON (41167-0061-1) / 8 CAPSULE, LIQU... Unisom SleepGels Nighttime Sleep-Aid Chattem, Inc. 2007-01-01
41167-0061-02 1 BOTTLE in 1 CARTON (41167-0061-2) / 100 CAPSULE, LIQUID F... Unisom SleepGels Nighttime Sleep-Aid Chattem, Inc. 2017-09-15
41167-0061-03 1 BOTTLE, PLASTIC in 1 CARTON (41167-0061-3) / 32 CAPSULE,... Unisom SleepGels Nighttime Sleep-Aid Chattem, Inc. 2007-01-01
41167-0061-05 1 BOTTLE, PLASTIC in 1 CARTON (41167-0061-5) / 40 CAPSULE,... Unisom SleepGels Nighttime Sleep-Aid Chattem, Inc. 2007-01-01
41167-0061-06 1 BOTTLE, PLASTIC in 1 CARTON (41167-0061-6) / 60 CAPSULE,... Unisom SleepGels Nighttime Sleep-Aid Chattem, Inc. 2007-01-01
42681-0051-01 1 BOTTLE in 1 CARTON (42681-0051-1) / 32 CAPSULE, LIQUID FI... Nighttime Sleep-Aid Whole Foods Market, INC. 2025-05-21
42806-0649-10 1000 CAPSULE in 1 BOTTLE (42806-649-10) Diphenhydramine Hydrochloride Epic Pharma, LLC 2016-11-22
Observed labelers: Bryant Ranch Prepack (10) · P & L Development, LLC (8) · Walgreens (8) · BIONPHARMA INC. (7) · CVS Pharmacy (7) · Dolgencorp, Inc. (DOLLAR GENERAL & REXALL) (7) · +65 more — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.