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Acetaminophen 21.7 MG/ML / dextromethorphan hydrobromide 0.667 MG/ML / guaifenesin 13.3 MG... — RxCUI 1042695

RxNorm drug concept · Semantic clinical drug
RxCUI 1042695 Semantic clinical drug · SCD ● Current RxNorm concept 5 FDA products 5 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1042695
Official nameAcetaminophen 21.7 MG/ML / dextromethorphan hydrobromide 0.667 MG/ML / guaifenesin 13.3 MG/ML Oral Solution
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known asacetaminophen 325 MG / dextromethorphan HBr 10 MG / guaiFENesin 200 MG in 15 mL Oral Solution; acetaminophen 650 MG / dextromethorphan HBr 20 MG / guaiFENesin 400 MG in 30 mL Oral Solution; APAP 21.7 MG/ML / Dextromethorphan Hydrobromide 0.667 MG/ML / Guaifenesin 13.3 MG/ML Oral Solution
FDA products mapped5
Package NDCs mapped5
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Acetaminophen Injection: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • Great question. The IV form is used when you can't take medication by mouth — for example, after surgery, if you're nauseated, or if you need faster, more reliable absorption. It d...
  • Why am I getting acetaminophen through an IV instead of just taking a pill?
  • Yes, Acetaminophen Injection is approved for children — for pain relief in kids 2 years and older, and for fever reduction in patients of all ages, including premature newborns bor...
  • The most important things to watch for are signs of a serious allergic reaction — swelling of your face, mouth, or throat, trouble breathing, or hives — and any new skin rash. Eith...
📖 Read our full Acetaminophen Injection guide →

🕸️ Concept Web — How Acetaminophen 21.7 MG/ML / dextromethorphan hydr... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Acetaminophen 21.7 MG/ML / dextromethorphan hydrobromide 0.667 MG/ML / guaifenesin 13.3 MG/ML Oral Solution RxCUI 1042695

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 5

    The active substance itself — no strength, form, or brand attached yet.

    • Acetaminophen 161
    • Dextromethorphan 3289
    • Guaifenesin 5032
    • Acetaminophen / dextromethorphan / guaifenesin 689775
    • Dextromethorphan hydrobromide 102490
  2. Dose forms 9

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Acetaminophen / dextromethorphan / guaifenesin Oral Solution 375971
    • Acetaminophen / dextromethorphan hydrobromide / guaifenesin Oral Solution 2646565
    • Acetaminophen / dextromethorphan / guaifenesin Oral Liquid Product 1155912
    • Acetaminophen / dextromethorphan / guaifenesin Oral Product 1155913
    • Acetaminophen / dextromethorphan hydrobromide / guaifenesin Oral Liquid Product 2659921
    • Acetaminophen / dextromethorphan hydrobromide / guaifenesin Oral Product 2662330
    • Oral Solution 316968
    • Oral Liquid Product 1151137
    • +1 more in this family
  3. Clinical & branded drugs 3

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

    • Acetaminophen 21.7 MG/ML 332581
    • Dextromethorphan hydrobromide 0.667 MG/ML 1014004
    • Guaifenesin 13.3 MG/ML 331390
  4. Packs 1

    Fixed collections of drugs packaged and sold together, like dose packs.

Showing up to 8 concepts per family — 17 of 18 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

📦 FDA Products & Package NDCs

5 products · 5 package NDCs
5 package NDCs map to RxCUI 1042695 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
00067-0104-08 245.5 mL in 1 BOTTLE (0067-0104-08) Theraflu Severe Cold Relief Chest Congestion Daytime Haleon US Holdings LLC 2023-12-01
00067-0107-01 1 KIT in 1 PACKAGE, COMBINATION (0067-0107-01) * 245.5 mL... Theraflu Severe Cold Relief Haleon US Holdings LLC 2024-02-01
11673-0739-02 1 KIT in 1 BOTTLE (11673-739-02) * 355 mL in 1 BOTTLE * 3... Daytime Severe and Nighttime Severe cold and flu TARGET CORPORATION 2024-05-01
11673-0791-02 1 KIT in 1 CARTON (11673-791-02) * 354 mL in 1 BOTTLE * 3... Daytime and Nighttime Severe Honey Cold and Flu TARGET CORPORATION 2024-05-01
55505-0217-36 237 mL in 1 BOTTLE, PLASTIC (55505-217-36) Safetussin High Blood Pressure and diabetes Cough, Cold and Flu KRAMER LABORATORIES 2023-04-17
Observed labelers: Haleon US Holdings LLC (2) · TARGET CORPORATION (2) · KRAMER LABORATORIES (1) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.