Diphenhydramine hydrochloride 1.67 MG/ML Oral Solution — RxCUI 1248354
RxNorm drug concept · Semantic clinical drug
RxCUI 1248354
Semantic clinical drug · SCD
● Current RxNorm concept 67 FDA products
97 package NDCs
Snapshot Jul 14, 2026
What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.
🗂️ Key Facts
RxCUI1248354
Official nameDiphenhydramine hydrochloride 1.67 MG/ML Oral Solution
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known asdiphenhydramine HCl 1.667 MG/ML Oral Solution; diphenhydrAMINE HCl 50 MG in 30 mL Oral Solution; diphenhydramine HCl 50 MG per 30 ML Oral Solution
FDA products mapped67
Package NDCs mapped97
Reported Medicaid activity (SDUD)23 prescriptions · 1 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026
📖 Skip the Codes — Read It in Plain English.
Our pharmacist-built guide to Diphenhydramine Topical: what it is, how it’s used, side effects, and interactions.
📗 Our plain-language guide HelloPharmacist
- You can use it for temporary relief of pain and itching from everyday skin problems — things like insect bites, minor burns, minor cuts and scrapes, and general skin irritations. I...
- What can I actually use this cream or spray for?
- You can apply it up to 3 to 4 times a day, but no more than that. More frequent use isn't going to help more — and the label is clear that you shouldn't exceed that limit. For kids...
- This is really important — do not use this topical product at the same time as any other product that contains diphenhydramine, even a pill or capsule. That includes allergy medici...
🕸️ Concept Web — How Diphenhydramine hydrochloride 1.67 MG/ML Oral So... Connects
One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept
Diphenhydramine hydrochloride 1.67 MG/ML Oral Solution
RxCUI 1248354 Semantic clinical drug · SCD
Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.
-
Ingredients 2
The active substance itself — no strength, form, or brand attached yet.
-
Diphenhydramine
3498IN -
Diphenhydramine hydrochloride
1362PIN
-
Diphenhydramine
-
Brand names 4
The same medicine's trade names. A brand name alone says nothing about strength or form.
-
Wal-Sleep Z
1363470BN -
Z-Sleep
1488697BN -
ZZZ Sleep
1437301BN -
Zzzquil
1233547BN
-
Wal-Sleep Z
-
Dose forms 25
The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.
-
Diphenhydramine Oral Solution
371889SCDF -
Diphenhydramine hydrochloride Oral Solution
2647041SCDFP -
Diphenhydramine Oral Liquid Product
1158448SCDG -
Diphenhydramine Oral Product
1158449SCDG -
Diphenhydramine hydrochloride Oral Liquid Product
2663691SCDGP -
Diphenhydramine hydrochloride Oral Product
2659104SCDGP -
Diphenhydramine Oral Solution [Wal-Sleep Z]
1437772SBDF -
Diphenhydramine Oral Solution [Z-Sleep]
1494597SBDF - +17 more in this family
-
Diphenhydramine Oral Solution
-
Clinical & branded drugs 9
Ingredient + strength + dose form. These are the concepts real FDA products actually carry.
-
Diphenhydramine hydrochloride 1.67 MG/ML
1092372SCDC -
Diphenhydramine hydrochloride 1.67 MG/ML Oral Solution [Wal-Sleep Z]
1437774SBD -
Diphenhydramine hydrochloride 1.67 MG/ML Oral Solution [Z-Sleep]
1494599SBD -
Diphenhydramine hydrochloride 1.67 MG/ML Oral Solution [ZZZ Sleep]
1437306SBD -
Diphenhydramine hydrochloride 1.67 MG/ML Oral Solution [Zzzquil]
1248356SBD -
Diphenhydramine hydrochloride 1.67 MG/ML [Wal-Sleep Z]
1437771SBDC -
Diphenhydramine hydrochloride 1.67 MG/ML [Z-Sleep]
1494596SBDC -
Diphenhydramine hydrochloride 1.67 MG/ML [ZZZ Sleep]
1437302SBDC - +1 more in this family
-
Diphenhydramine hydrochloride 1.67 MG/ML
Showing up to 8 concepts per family — 22 of 40 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.
🔀 Generic ⇄ Brand Crosswalk
The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.
Generic (Clinical) Concepts
-
Diphenhydramine hydrochloride 1.67 MG/ML
SCDC · 1092372 -
Diphenhydramine Oral Solution
SCDF · 371889 -
Diphenhydramine hydrochloride Oral Solution
SCDFP · 2647041 -
Diphenhydramine Oral Liquid Product
SCDG · 1158448 -
Diphenhydramine Oral Product
SCDG · 1158449 -
Diphenhydramine hydrochloride Oral Liquid Product
SCDGP · 2663691 -
Diphenhydramine hydrochloride Oral Product
SCDGP · 2659104
Brand-Name Concepts
-
Diphenhydramine hydrochloride 1.67 MG/ML Oral Solution [Wal-Sleep Z]
SBD · 1437774 -
Diphenhydramine hydrochloride 1.67 MG/ML Oral Solution [ZZZ Sleep]
SBD · 1437306 -
Diphenhydramine hydrochloride 1.67 MG/ML Oral Solution [Zzzquil]
SBD · 1248356 -
Diphenhydramine hydrochloride 1.67 MG/ML Oral Solution [Z-Sleep]
SBD · 1494599 -
Diphenhydramine hydrochloride 1.67 MG/ML [Wal-Sleep Z]
SBDC · 1437771 -
Diphenhydramine hydrochloride 1.67 MG/ML [Z-Sleep]
SBDC · 1494596 -
Diphenhydramine hydrochloride 1.67 MG/ML [ZZZ Sleep]
SBDC · 1437302 -
Diphenhydramine hydrochloride 1.67 MG/ML [Zzzquil]
SBDC · 1248355 -
Diphenhydramine Oral Solution [Wal-Sleep Z]
SBDF · 1437772 -
Diphenhydramine Oral Solution [Z-Sleep]
SBDF · 1494597
📦 FDA Products & Package NDCs
67 products · 97 package NDCs
97 package NDCs map to RxCUI 1248354 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
| Package NDC | Package | Brand / generic name | Labeler | Marketing start |
|---|---|---|---|---|
| 50844-0250-45 | 177 mL in 1 BOTTLE, PLASTIC (50844-250-45) | Nighttime Sleep Aid | L.N.K. International, Inc. | 2019-07-20 |
| 53041-0633-58 | 177 mL in 1 BOTTLE (53041-633-58) | Nighttime Sleep-Aid | Guardian Drug Company | 2024-01-11 |
| 53942-0522-28 | 354 mL in 1 BOTTLE (53942-522-28) | Nighttime Sleep-Aid | DeMoulas Market Basket | 2013-09-19 |
| 53943-0522-25 | 117 mL in 1 BOTTLE (53943-522-25) | NIGHT TIME SLEEP-AID | Discount Drug Mart | 2013-12-10 |
| 53943-0522-28 | 354 mL in 1 BOTTLE (53943-522-28) | NIGHT TIME SLEEP-AID | Discount Drug Mart | 2013-12-10 |
| 55319-0802-02 | 355 mL in 1 BOTTLE, PLASTIC (55319-802-02) | Nighttime Sleep Aid | Family Dollar Services Inc | 2024-04-05 |
| 55319-0802-45 | 177 mL in 1 BOTTLE, PLASTIC (55319-802-45) | Nighttime Sleep Aid | Family Dollar Services Inc | 2024-04-05 |
| 55910-0114-12 | 355 mL in 1 BOTTLE, PLASTIC (55910-114-12) | Night Time Sleep Aid | Dolgencorp, Inc. (DOLLAR GENERAL & REXALL) | 2015-03-31 |
| 55910-0186-34 | 237 mL in 1 BOTTLE (55910-186-34) | dg health sleep aid | Dolgencorp, LLC | 2018-04-05 |
| 55910-0899-12 | 355 mL in 1 BOTTLE, PLASTIC (55910-899-12) | Sleep Aid NightTime | Dolgencorp, Inc. (DOLLAR GENERAL & REXALL) | 2018-03-31 |
| 55910-0981-02 | 355 mL in 1 BOTTLE, PLASTIC (55910-981-02) | Sleep Aid NightTime | Dolgencorp, Inc. (DOLLAR GENERAL & REXALL) | 2022-02-04 |
| 55910-0981-04 | 2 BOTTLE, PLASTIC in 1 PACKAGE (55910-981-04) / 355 mL in 1... | Sleep Aid NightTime | Dolgencorp, Inc. (DOLLAR GENERAL & REXALL) | 2022-02-04 |
| 59779-0893-06 | 177 mL in 1 BOTTLE, PLASTIC (59779-893-06) | CVS Health Nighttime Sleep-Aid | CVS Pharmacy,Inc. | 2015-09-22 |
| 59779-0893-12 | 354 mL in 1 BOTTLE, PLASTIC (59779-893-12) | CVS Health Nighttime Sleep-Aid | CVS Pharmacy,Inc. | 2015-02-11 |
| 59779-0893-24 | 2 BOTTLE in 1 PACKAGE, COMBINATION (59779-893-24) / 354 mL... | CVS Health Nighttime Sleep-Aid | CVS Pharmacy,Inc. | 2016-07-14 |
| 66715-6543-04 | 177 mL in 1 BOTTLE, PLASTIC (66715-6543-4) | Nighttime Sleep Aid, 24-7 Life BY 7-ELEVEN, 6oz | Lil' Drug Store Products, Inc. | 2022-04-19 |
| 67091-0630-06 | 177 mL in 1 BOTTLE, PLASTIC (67091-630-06) | Nighttime Sleep Aid Berry Flavor | WINCO FOODS, LLC | 2023-01-09 |
| 68016-0219-12 | 354 mL in 1 BOTTLE, PLASTIC (68016-219-12) | Premier Value Nighttime Sleep-Aid Liquid Sleep-Aid | Chain Drug Consortium | 2012-12-10 |
| 68163-0730-06 | 177 mL in 1 BOTTLE, PLASTIC (68163-730-06) | Nighttime Sleep Aid Berry Flavor | Raritan Pharmaceuticals Inc | 2019-04-17 |
| 68391-0186-40 | 3 BOTTLE in 1 CARTON (68391-186-40) / 355 mL in 1 BOTTLE | berkley and jensen sleep aid | BJWC | 2020-07-23 |
| 68391-0793-09 | 3 BOTTLE in 1 PACKAGE (68391-793-09) / 354 mL in 1 BOTTLE (... | Nighttime Sleep Aid | BJWC (Berkley & Jensen / BJ's) | 2025-08-20 |
| 69168-0446-39 | 354 mL in 1 BOTTLE (69168-446-39) | Nighttime Sleep Aid | Allegiant Health | 2024-01-16 |
| 69168-0486-39 | 355 mL in 1 BOTTLE (69168-486-39) | Nighttime Sleep Aid | Allegiant Health | 2025-08-06 |
| 69423-0795-12 | 354 mL in 1 BOTTLE, PLASTIC (69423-795-12) | VICKS ZzzQuil NIGHTTIME SLEEP-AID Diphenhydramine HCl FREE OF | The Procter & Gamble Manufacturing Company | 2021-04-19 |
| 69423-0812-12 | 354 mL in 1 BOTTLE, PLASTIC (69423-812-12) | VICKS ZzzQuil NIGHTTIME SLEEP-AID | The Procter & Gamble Manufacturing Company | 2021-10-11 |
| 69423-0812-24 | 2 BOTTLE, PLASTIC in 1 CARTON (69423-812-24) / 354 mL in 1... | VICKS ZzzQuil NIGHTTIME SLEEP-AID | The Procter & Gamble Manufacturing Company | 2021-10-11 |
| 69423-0830-12 | 354 mL in 1 BOTTLE, PLASTIC (69423-830-12) | Vicks ZzzQuil Soothing Sleep Nighttime Sleep-Aid | The Procter & Gamble Manufacturing Company | 2024-02-06 |
| 69423-0830-24 | 2 BOTTLE, PLASTIC in 1 CARTON (69423-830-24) / 354 mL in 1... | Vicks ZzzQuil Soothing Sleep Nighttime Sleep-Aid | The Procter & Gamble Manufacturing Company | 2024-02-06 |
| 69842-0470-02 | 355 mL in 1 BOTTLE, PLASTIC (69842-470-02) | Sleep-Aid | CVS PHARMACY | 2019-03-01 |
| 69842-0753-12 | 354 mL in 1 BOTTLE, PLASTIC (69842-753-12) | CVS Health Nighttime Sleep Aid | CVS Pharmacy,Inc. | 2017-10-11 |
| 70000-0174-01 | 354 mL in 1 BOTTLE, PLASTIC (70000-0174-1) | LEADER Nighttime Sleep-Aid | CARDINAL HEALTH | 2017-01-17 |
| 70000-0174-02 | 177 mL in 1 BOTTLE, PLASTIC (70000-0174-2) | LEADER Nighttime Sleep-Aid | CARDINAL HEALTH | 2017-03-13 |
| 72288-0186-40 | 355 mL in 1 BOTTLE (72288-186-40) | basic care nighttime sleep aid | Amazon.com Services LLC | 2021-08-06 |
| 76162-0200-45 | 177 mL in 1 BOTTLE, PLASTIC (76162-200-45) | Nighttime Sleep Aid | TOPCO ASSOCIATES LLC | 2023-01-11 |
| 76281-0522-24 | 118 mL in 1 BOTTLE (76281-522-24) | Nighttime Sleep-Aid Non-Habit Forming | AptaPharma Inc. | 2018-01-01 |
| 76281-0522-25 | 177 mL in 1 BOTTLE (76281-522-25) | Nighttime Sleep-Aid Non-Habit Forming | AptaPharma Inc. | 2018-01-01 |
| 76281-0522-28 | 354 mL in 1 BOTTLE (76281-522-28) | Nighttime Sleep-Aid Non-Habit Forming | AptaPharma Inc. | 2018-01-01 |
| 82501-0186-00 | 355 mL in 1 BOTTLE (82501-0186-0) | GOODNOW SLEEP AID | Gobrands, Inc | 2025-10-23 |
| 83324-0015-06 | 177 mL in 1 BOTTLE (83324-015-06) | Nighttime Sleep-Aid | Chain Drug Marketing Association Inc. | 2024-03-19 |
| 83324-0336-06 | 177 mL in 1 BOTTLE, PLASTIC (83324-336-06) | QUALITY CHOICE NIGHTTIME SLEEP AID | QUALITY CHOICE (CHAIN DRUG MARKETING ASSOCIATION) | 2025-08-04 |
| 84126-0306-03 | 1 KIT in 1 CARTON (84126-306-03) * 2 BOTTLE, PLASTIC in 1... | Vicks ZzzQuil Nighttime Sleep-Aid | The Procter & Gamble Manufacturing Company | 2024-07-15 |
| 84126-0316-04 | 118 mL in 1 BOTTLE, PLASTIC (84126-316-04) | ZzzQuil Nighttime Sleep-Aid | The Procter & Gamble Manufacturing Company | 2024-06-15 |
| 84126-0370-12 | 354 mL in 1 BOTTLE, PLASTIC (84126-370-12) | VICKS ZzzQuil FREE and CLEAR NIGHTTIME SLEEP-AID | The Procter & Gamble Manufacturing Company | 2026-02-03 |
| 84126-0370-24 | 2 BOTTLE, PLASTIC in 1 PACKAGE (84126-370-24) / 354 mL in 1... | VICKS ZzzQuil FREE and CLEAR NIGHTTIME SLEEP-AID | The Procter & Gamble Manufacturing Company | 2026-02-03 |
| 84126-0371-12 | 354 mL in 1 BOTTLE, PLASTIC (84126-371-12) | VICKS ZzzQuil FREE and CLEAR NIGHTTIME SLEEP-AID | The Procter & Gamble Manufacturing Company | 2026-02-03 |
| 84379-0284-04 | 118 mL in 1 BOTTLE (84379-284-04) | REVASOL SLEEP AID | Rnv LLC | 2025-02-03 |
| 85828-0793-01 | 354 mL in 1 BOTTLE (85828-793-01) | Nighttime Sleep Aid | Grocery Outlet, Inc. | 2026-03-12 |
Observed labelers:
The Procter & Gamble Manufacturing Company (16) ·
WALGREEN COMPANY (6) ·
CVS Pharmacy,Inc. (4) ·
Dolgencorp, Inc. (DOLLAR GENERAL & REXALL) (4) ·
Rite Aid Corporation (4) ·
Wal-Mart Stores Inc (4)
· +37 more — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.
🗃️ Sources & Limits
Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
- A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
- Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
- Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
- Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.
Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.