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Diphenhydramine hydrochloride 20 MG/ML / pramoxine hydrochloride 10 MG/ML Topical Lotion — RxCUI 1292321

Name: Diphenhydramine hydrochloride 20 MG/ML / pramoxine hydrochloride 10 MG/ML Topical Lot… (RxCUI 1292321)
Creator: Brian Staiger, PharmD

RxNorm drug concept · Semantic clinical drug

RxCUI 1292321 Semantic clinical drug · SCD ● Current RxNorm concept 1 FDA product 2 package NDCs Snapshot Jul 14, 2026

This page is curated, coded, and maintained by Dr. Brian Staiger, PharmD

Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1292321

Official nameDiphenhydramine hydrochloride 20 MG/ML / pramoxine hydrochloride 10 MG/ML Topical Lotion

Concept typeSemantic clinical drug (SCD)

RxNorm statusCurrent RxNorm concept

Also known asdiphenhydramine hydrochloride 2 % / pramoxine hydrochloride 1 % Topical Lotion; diphenhydrAMINE HCl 2 % / pramoxine HCl 1 % Topical Lotion

FDA products mapped1

Package NDCs mapped2

RxNorm release07/06/2026

Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Diphenhydramine Topical: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist

It gives temporary relief of pain and itching on the skin. That includes minor burns, minor cuts or scrapes, insect bites, minor skin irritations, and rashes from poison ivy, oak o...
Adults and children 2 and older can apply it to the affected area no more than 3 to 4 times a day. Don't use it more often than directed. For a child under 2, check with a doctor f...
No. Don't use it on large areas of the body or on broken, blistered or oozing skin. Also avoid it on chicken pox or sunburn.
Can I put it on a large area or on blistered skin?

📖 Read our full Diphenhydramine Topical guide →

🕸️ Concept Web — How Diphenhydramine hydrochloride 20 MG/ML / pramoxi... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.

This page's concept Diphenhydramine hydrochloride 20 MG/ML / pramoxine hydrochloride 10 MG/ML Topical Lotion RxCUI 1292321 Semantic clinical drug · SCD

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

Ingredients 5

The active substance itself — no strength, form, or brand attached yet.
- Diphenhydramine 3498 IN
- Pramoxine 34347 IN
- Diphenhydramine / pramoxine 1008705 MIN
- Diphenhydramine hydrochloride 1362 PIN
- Pramoxine hydrochloride 57555 PIN
Dose forms 6

The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.
- Diphenhydramine / pramoxine Topical Lotion 379016 SCDF
- Diphenhydramine hydrochloride / pramoxine hydrochloride Topical Lotion 2648859 SCDFP
- Diphenhydramine / pramoxine Topical Product 1158444 SCDG
- Diphenhydramine hydrochloride / pramoxine hydrochloride Topical Product 2659861 SCDGP
- Topical Lotion 316983 DF
- Topical Product 1151122 DFG
Clinical & branded drugs 2

Ingredient + strength + dose form. These are the concepts real FDA products actually carry.
- Diphenhydramine hydrochloride 20 MG/ML 1049097 SCDC
- Pramoxine hydrochloride 10 MG/ML 828361 SCDC

Showing up to 8 concepts per family — 13 of 13 stored related concepts drawn.

These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

Diphenhydramine hydrochloride 20 MG/ML SCDC · 1049097
Pramoxine hydrochloride 10 MG/ML SCDC · 828361
Diphenhydramine / pramoxine Topical Lotion SCDF · 379016
Diphenhydramine hydrochloride / pramoxine hydrochloride Topical Lotion SCDFP · 2648859
Diphenhydramine / pramoxine Topical Product SCDG · 1158444
Diphenhydramine hydrochloride / pramoxine hydrochloride Topical Product SCDGP · 2659861

📦 FDA Products & Package NDCs

1 product · 2 package NDCs

2 package NDCs map to RxCUI 1292321 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.

Package NDC	Package	Brand / generic name	Labeler	Marketing start
11383-0192-01	1 BOTTLE in 1 CARTON (11383-192-01) / 118 mL in 1 BOTTLE	Bite and Itch	Weeks & Leo Co., Inc.	2015-06-15
11383-0192-04	118 mL in 1 BOTTLE (11383-192-04)	Bite and Itch	Weeks & Leo Co., Inc.	2015-06-15

Observed labelers: Weeks & Leo Co., Inc. (2) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7

openFDA export observedJul 14, 2026

RxNorm release07/06/2026

Methodology2026-07-full-catalog-v1

A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.

This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.