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Spironolactone 50 MG Oral Tablet — RxCUI 198223

RxNorm drug concept · Semantic clinical drug
RxCUI 198223 Semantic clinical drug · SCD ● Current RxNorm concept 100 FDA products 311 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI198223
Official nameSpironolactone 50 MG Oral Tablet
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
FDA products mapped100
Package NDCs mapped311
Reported Medicaid activity (SDUD)2,510,271 prescriptions · 52 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Spironolactone: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • Spironolactone has a few different uses depending on your situation. Most commonly, it's prescribed to treat moderate-to-severe heart failure, high blood pressure, or fluid buildup...
  • What exactly is spironolactone used for?
  • Yes, it actually matters quite a bit. Food can nearly double the amount of spironolactone your body absorbs. That doesn't mean you must always take it with food — but you should pi...
  • Does it matter if I take it with food or not?
📖 Read our full Spironolactone guide →

🕸️ Concept Web — How Spironolactone 50 MG Oral Tablet Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Spironolactone 50 MG Oral Tablet RxCUI 198223

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 1

    The active substance itself — no strength, form, or brand attached yet.

    • Spironolactone 9997
  2. Brand names 1

    The same medicine's trade names. A brand name alone says nothing about strength or form.

    • Aldactone 151317
  3. Dose forms 9

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Spironolactone Oral Tablet 373946
    • Spironolactone Oral Product 1161122
    • Spironolactone Pill 1161123
    • Spironolactone Oral Tablet [Aldactone] 368071
    • Aldactone Oral Product 1174848
    • Aldactone Pill 1174849
    • Oral Tablet 317541
    • Oral Product 1151131
    • +1 more in this family
  4. Clinical & branded drugs 3

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

Showing up to 8 concepts per family — 13 of 14 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

  • Spironolactone 50 MG SCDC · 317508
  • Spironolactone Oral Tablet SCDF · 373946
  • Spironolactone Oral Product SCDG · 1161122
  • Spironolactone Pill SCDG · 1161123

Brand-Name Concepts

  • Spironolactone 50 MG Oral Tablet [Aldactone] SBD · 200817
  • Spironolactone 50 MG [Aldactone] SBDC · 565465
  • Spironolactone Oral Tablet [Aldactone] SBDF · 368071
  • Aldactone Oral Product SBDG · 1174848
  • Aldactone Pill SBDG · 1174849
  • Aldactone BN · 151317

📦 FDA Products & Package NDCs

100 products · 311 package NDCs
311 package NDCs map to RxCUI 198223 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
59746-0217-09 500 TABLET, FILM COATED in 1 BOTTLE (59746-217-09) Spironolactone Jubilant Cadista Pharmacuticals Inc. 2017-04-04
59746-0218-01 100 TABLET, FILM COATED in 1 BOTTLE (59746-218-01) Spironolactone Jubilant Cadista Pharmacuticals Inc. 2017-04-04
59746-0218-05 500 TABLET, FILM COATED in 1 BOTTLE (59746-218-05) Spironolactone Jubilant Cadista Pharmacuticals Inc. 2017-04-04
59746-0218-06 100 TABLET, FILM COATED in 1 BOTTLE (59746-218-06) Spironolactone Jubilant Cadista Pharmacuticals Inc. 2017-04-04
59746-0218-09 500 TABLET, FILM COATED in 1 BOTTLE (59746-218-09) Spironolactone Jubilant Cadista Pharmacuticals Inc. 2017-04-04
60687-0465-01 100 BLISTER PACK in 1 BOX, UNIT-DOSE (60687-465-01) / 1 TAB... Spironolactone American Health Packaging 2019-06-06
60687-0476-01 100 BLISTER PACK in 1 BOX, UNIT-DOSE (60687-476-01) / 1 TAB... Spironolactone American Health Packaging 2019-06-06
60687-0487-01 100 BLISTER PACK in 1 BOX, UNIT-DOSE (60687-487-01) / 1 TAB... Spironolactone American Health Packaging 2019-06-06
63187-0861-30 30 TABLET, FILM COATED in 1 BOTTLE (63187-861-30) Spironolactone Proficient Rx LP 2017-06-01
63187-0861-60 60 TABLET, FILM COATED in 1 BOTTLE (63187-861-60) Spironolactone Proficient Rx LP 2017-06-01
63187-0861-90 90 TABLET, FILM COATED in 1 BOTTLE (63187-861-90) Spironolactone Proficient Rx LP 2017-06-01
63629-1065-01 100 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (63629-1065-1) SPIRONOLACTONE Bryant Ranch Prepack 1986-07-23
63629-1066-01 500 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (63629-1066-1) SPIRONOLACTONE Bryant Ranch Prepack 1986-07-23
63629-1067-01 30 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (63629-1067-1) SPIRONOLACTONE Bryant Ranch Prepack 2020-09-21
63629-1067-02 60 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (63629-1067-2) SPIRONOLACTONE Bryant Ranch Prepack 2020-12-01
63629-1067-03 90 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (63629-1067-3) SPIRONOLACTONE Bryant Ranch Prepack 2020-12-14
63629-1067-04 500 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (63629-1067-4) SPIRONOLACTONE Bryant Ranch Prepack 2022-10-26
63629-2438-01 100 TABLET, FILM COATED in 1 BOTTLE (63629-2438-1) Spironolactone Bryant Ranch Prepack 2017-04-04
63629-5341-01 30 TABLET, FILM COATED in 1 BOTTLE (63629-5341-1) SPIRONOLACTONE Bryant Ranch Prepack 2014-05-16
63629-5341-02 60 TABLET, FILM COATED in 1 BOTTLE (63629-5341-2) SPIRONOLACTONE Bryant Ranch Prepack 2017-10-16
63629-5341-03 90 TABLET, FILM COATED in 1 BOTTLE (63629-5341-3) SPIRONOLACTONE Bryant Ranch Prepack 2016-02-18
63629-5341-04 100 TABLET, FILM COATED in 1 BOTTLE (63629-5341-4) SPIRONOLACTONE Bryant Ranch Prepack 2023-03-09
63629-5341-05 14 TABLET, FILM COATED in 1 BOTTLE (63629-5341-5) SPIRONOLACTONE Bryant Ranch Prepack 2023-03-09
63629-5341-06 10 TABLET, FILM COATED in 1 BOTTLE (63629-5341-6) SPIRONOLACTONE Bryant Ranch Prepack 2023-03-09
64980-0706-01 100 TABLET in 1 BOTTLE (64980-706-01) Spironolactone Rising Pharma Holdings, Inc. 2025-09-15
64980-0706-50 500 TABLET in 1 BOTTLE (64980-706-50) Spironolactone Rising Pharma Holdings, Inc. 2025-09-15
64980-0707-01 100 TABLET in 1 BOTTLE (64980-707-01) Spironolactone Rising Pharma Holdings, Inc. 2025-09-15
64980-0707-50 500 TABLET in 1 BOTTLE (64980-707-50) Spironolactone Rising Pharma Holdings, Inc. 2025-09-15
64980-0708-01 100 TABLET in 1 BOTTLE (64980-708-01) Spironolactone Rising Pharma Holdings, Inc. 2025-09-15
64980-0708-50 500 TABLET in 1 BOTTLE (64980-708-50) Spironolactone Rising Pharma Holdings, Inc. 2025-09-15
65162-0511-03 30 TABLET in 1 BOTTLE (65162-511-03) Spironolactone Amneal Pharmaceuticals LLC 2010-08-02
65162-0511-06 60 TABLET in 1 BOTTLE (65162-511-06) Spironolactone Amneal Pharmaceuticals LLC 2010-08-02
65162-0511-09 90 TABLET in 1 BOTTLE (65162-511-09) Spironolactone Amneal Pharmaceuticals LLC 2010-08-02
65162-0511-10 100 TABLET in 1 BOTTLE (65162-511-10) Spironolactone Amneal Pharmaceuticals LLC 2010-08-02
65162-0511-11 1000 TABLET in 1 BOTTLE (65162-511-11) Spironolactone Amneal Pharmaceuticals LLC 2010-08-02
65162-0511-50 500 TABLET in 1 BOTTLE (65162-511-50) Spironolactone Amneal Pharmaceuticals LLC 2010-08-02
65162-0511-60 100 TABLET in 1 BLISTER PACK (65162-511-60) Spironolactone Amneal Pharmaceuticals LLC 2010-08-02
65162-0514-03 30 TABLET in 1 BOTTLE (65162-514-03) Spironolactone Amneal Pharmaceuticals LLC 2010-08-02
65162-0514-06 60 TABLET in 1 BOTTLE (65162-514-06) Spironolactone Amneal Pharmaceuticals LLC 2010-08-02
65162-0514-09 90 TABLET in 1 BOTTLE (65162-514-09) Spironolactone Amneal Pharmaceuticals LLC 2010-08-02
65162-0514-10 100 TABLET in 1 BOTTLE (65162-514-10) Spironolactone Amneal Pharmaceuticals LLC 2010-08-02
65162-0514-11 1000 TABLET in 1 BOTTLE (65162-514-11) Spironolactone Amneal Pharmaceuticals LLC 2010-08-02
65162-0514-50 500 TABLET in 1 BOTTLE (65162-514-50) Spironolactone Amneal Pharmaceuticals LLC 2010-08-02
65162-0514-60 100 TABLET in 1 BLISTER PACK (65162-514-60) Spironolactone Amneal Pharmaceuticals LLC 2010-08-02
65162-0515-03 30 TABLET in 1 BOTTLE (65162-515-03) Spironolactone Amneal Pharmaceuticals LLC 2010-08-02
65162-0515-06 60 TABLET in 1 BOTTLE (65162-515-06) Spironolactone Amneal Pharmaceuticals LLC 2010-08-02
65162-0515-09 90 TABLET in 1 BOTTLE (65162-515-09) Spironolactone Amneal Pharmaceuticals LLC 2010-08-02
65162-0515-10 100 TABLET in 1 BOTTLE (65162-515-10) Spironolactone Amneal Pharmaceuticals LLC 2010-08-02
65162-0515-11 1000 TABLET in 1 BOTTLE (65162-515-11) Spironolactone Amneal Pharmaceuticals LLC 2010-08-02
65162-0515-50 500 TABLET in 1 BOTTLE (65162-515-50) Spironolactone Amneal Pharmaceuticals LLC 2010-08-02
Observed labelers: Proficient Rx LP (37) · Asclemed USA, Inc. (36) · Bryant Ranch Prepack (27) · Amneal Pharmaceuticals LLC (21) · Amneal Pharmaceuticals of New York LLC (18) · Zydus Lifesciences Limited (18) · +25 more — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.