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Acetaminophen 500 MG Oral Tablet [Tylenol] — RxCUI 209459

RxNorm drug concept · Semantic branded drug
RxCUI 209459 Semantic branded drug · SBD ● Current RxNorm concept 31 FDA products 116 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI209459
Official nameAcetaminophen 500 MG Oral Tablet [Tylenol]
Concept typeSemantic branded drug (SBD)
RxNorm statusCurrent RxNorm concept
Also known asTylenol 500 MG Oral Tablet; Tylenol Extra Strength 500 MG Oral Tablet; APAP 500 MG Oral Tablet [Tylenol]
FDA products mapped31
Package NDCs mapped116
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Acetaminophen Injection: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • Great question. The IV form is used when you can't take medication by mouth — for example, after surgery, if you're nauseated, or if you need faster, more reliable absorption. It d...
  • Why am I getting acetaminophen through an IV instead of just taking a pill?
  • Yes, Acetaminophen Injection is approved for children — for pain relief in kids 2 years and older, and for fever reduction in patients of all ages, including premature newborns bor...
  • The most important things to watch for are signs of a serious allergic reaction — swelling of your face, mouth, or throat, trouble breathing, or hives — and any new skin rash. Eith...
📖 Read our full Acetaminophen Injection guide →

🕸️ Concept Web — How Acetaminophen 500 MG Oral Tablet [Tylenol] Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Acetaminophen 500 MG Oral Tablet [Tylenol] RxCUI 209459

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 1

    The active substance itself — no strength, form, or brand attached yet.

    • Acetaminophen 161
  2. Brand names 1

    The same medicine's trade names. A brand name alone says nothing about strength or form.

    • Tylenol 202433
  3. Dose forms 9

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Acetaminophen Oral Tablet 369097
    • Acetaminophen Oral Product 1152842
    • Acetaminophen Pill 1152843
    • Acetaminophen Oral Tablet [Tylenol] 369070
    • Tylenol Oral Product 1187311
    • Tylenol Pill 1187315
    • Oral Tablet 317541
    • Oral Product 1151131
    • +1 more in this family
  4. Clinical & branded drugs 3

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

Showing up to 8 concepts per family — 13 of 14 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

  • Acetaminophen 500 MG Oral Tablet SCD · 198440
  • Acetaminophen 500 MG SCDC · 315266
  • Acetaminophen Oral Tablet SCDF · 369097
  • Acetaminophen Oral Product SCDG · 1152842
  • Acetaminophen Pill SCDG · 1152843

Brand-Name Concepts

  • Acetaminophen 500 MG [Tylenol] SBDC · 570070
  • Acetaminophen Oral Tablet [Tylenol] SBDF · 369070
  • Tylenol Oral Product SBDG · 1187311
  • Tylenol Pill SBDG · 1187315
  • Tylenol BN · 202433

📦 FDA Products & Package NDCs

31 products · 116 package NDCs
116 package NDCs map to RxCUI 209459 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
50090-0005-00 1 BOTTLE, PLASTIC in 1 CARTON (50090-0005-0) / 24 TABLET, F... TYLENOL EXTRA STRENGTH A-S Medication Solutions 2014-11-28
50090-1695-00 1 BOTTLE, PLASTIC in 1 CARTON (50090-1695-0) / 24 TABLET, F... Tylenol Extra Strength A-S Medication Solutions 2015-02-12
50090-5469-00 1 BOTTLE in 1 CARTON (50090-5469-0) / 24 TABLET, FILM COATE... TYLENOL EXTRA STRENGTH A-S Medication Solutions 2021-02-17
50269-0008-06 6 BLISTER PACK in 1 BOX (50269-008-06) / 2 POUCH in 1 BLIST... Tylenol Extra Strength JC World Bell Wholesale Co., Inc. 2019-11-15
50269-0449-20 20 POUCH in 1 BOX (50269-449-20) / 2 TABLET, FILM COATED in... Tylenol Extra Strength JC World Bell Wholesale Co., Inc. 2018-09-20
50269-0449-25 25 POUCH in 1 BOX (50269-449-25) / 2 TABLET, FILM COATED in... Tylenol Extra Strength JC World Bell Wholesale Co., Inc. 2018-09-20
50580-0108-25 1 BOTTLE in 1 CARTON (50580-108-25) / 225 TABLET, FILM COAT... TYLENOL Extra Strength Kenvue Brands LLC 2025-10-13
50580-0142-01 1 KIT in 1 KIT (50580-142-01) * 1 BOTTLE in 1 CARTON (5058... TYLENOL Extra Strength / TYLENOL Precise Cooling Pain Relief Kenvue Brands LLC 2024-11-25
50580-0378-01 1 BOTTLE, PLASTIC in 1 CARTON (50580-378-01) / 24 TABLET, F... Tylenol Extra Strength Kenvue Brands LLC 2014-11-01
50580-0378-02 1 BOTTLE, PLASTIC in 1 CARTON (50580-378-02) / 100 TABLET,... Tylenol Extra Strength Kenvue Brands LLC 2014-11-01
50580-0378-03 225 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (50580-378-03) Tylenol Extra Strength Kenvue Brands LLC 2015-04-06
50580-0378-04 1 BOTTLE, PLASTIC in 1 CARTON (50580-378-04) / 24 TABLET, F... Tylenol Extra Strength Kenvue Brands LLC 2021-03-01
50580-0378-05 1 BOTTLE, PLASTIC in 1 CARTON (50580-378-05) / 50 TABLET, F... Tylenol Extra Strength Kenvue Brands LLC 2021-03-01
50580-0378-06 1 BOTTLE, PLASTIC in 1 CARTON (50580-378-06) / 100 TABLET,... Tylenol Extra Strength Kenvue Brands LLC 2021-03-01
50580-0378-07 1 BOTTLE, PLASTIC in 1 CARTON (50580-378-07) / 225 TABLET,... Tylenol Extra Strength Kenvue Brands LLC 2021-03-01
50580-0378-08 325 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (50580-378-08) Tylenol Extra Strength Kenvue Brands LLC 2021-03-01
50580-0378-37 320 TABLET, FILM COATED in 1 BOTTLE (50580-378-37) Tylenol Extra Strength Kenvue Brands LLC 2026-03-31
50580-0449-00 1 BOTTLE, PLASTIC in 1 CARTON (50580-449-00) / 125 TABLET,... TYLENOL Extra Strength Kenvue Brands LLC 1984-08-19
50580-0449-05 1 BOTTLE, PLASTIC in 1 CARTON (50580-449-05) / 24 TABLET, F... TYLENOL Extra Strength Kenvue Brands LLC 1984-08-19
50580-0449-08 2 TABLET, FILM COATED in 1 POUCH (50580-449-08) TYLENOL Extra Strength Kenvue Brands LLC 1984-08-19
50580-0449-09 1 BOTTLE, PLASTIC in 1 CARTON (50580-449-09) / 100 TABLET,... TYLENOL Extra Strength Kenvue Brands LLC 1984-08-19
50580-0449-10 50 POUCH in 1 TRAY (50580-449-10) / 2 TABLET, FILM COATED i... TYLENOL Extra Strength Kenvue Brands LLC 1984-08-19
50580-0449-11 50 POUCH in 1 TRAY (50580-449-11) / 2 TABLET, FILM COATED i... TYLENOL Extra Strength Kenvue Brands LLC 1984-08-19
50580-0449-12 12 VIAL, PLASTIC in 1 PACKAGE (50580-449-12) / 10 TABLET, F... TYLENOL Extra Strength Kenvue Brands LLC 2014-10-21
50580-0449-13 3 POUCH in 1 CARTON (50580-449-13) / 2 TABLET, FILM COATED... TYLENOL Extra Strength Kenvue Brands LLC 1984-08-19
50580-0449-14 2 TABLET, FILM COATED in 1 POUCH (50580-449-14) TYLENOL Extra Strength Kenvue Brands LLC 1984-08-19
50580-0449-15 10 TABLET, FILM COATED in 1 VIAL, PLASTIC (50580-449-15) TYLENOL Extra Strength Kenvue Brands LLC 1984-08-19
50580-0449-23 1 BOTTLE, PLASTIC in 1 CARTON (50580-449-23) / 150 TABLET,... TYLENOL Extra Strength Kenvue Brands LLC 1984-08-19
50580-0449-31 1 BOTTLE, PLASTIC in 1 CARTON (50580-449-31) / 36 TABLET, F... TYLENOL Extra Strength Kenvue Brands LLC 1984-08-19
50580-0449-34 325 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (50580-449-34) TYLENOL Extra Strength Kenvue Brands LLC 1984-08-19
50580-0449-35 1 BOTTLE, PLASTIC in 1 CARTON (50580-449-35) / 24 TABLET, F... TYLENOL Extra Strength Kenvue Brands LLC 1984-08-19
50580-0449-36 1 BOTTLE, PLASTIC in 1 CARTON (50580-449-36) / 100 TABLET,... TYLENOL Extra Strength Kenvue Brands LLC 1984-08-19
50580-0449-37 320 TABLET, FILM COATED in 1 BOTTLE (50580-449-37) TYLENOL Extra Strength Kenvue Brands LLC 2026-03-31
50580-0449-61 1 BOTTLE, PLASTIC in 1 CARTON (50580-449-61) / 225 TABLET,... TYLENOL Extra Strength Kenvue Brands LLC 1984-08-19
50580-0449-62 325 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (50580-449-62) TYLENOL Extra Strength Kenvue Brands LLC 1984-08-19
50580-0449-66 2 BOTTLE in 1 CARTON (50580-449-66) / 100 TABLET, FILM COAT... TYLENOL Extra Strength Kenvue Brands LLC 2024-05-01
50580-0449-84 2 TABLET, FILM COATED in 1 POUCH (50580-449-84) TYLENOL Extra Strength Kenvue Brands LLC 1984-08-19
50580-0449-85 50 POUCH in 1 TRAY (50580-449-85) / 2 TABLET, FILM COATED i... TYLENOL Extra Strength Kenvue Brands LLC 1984-08-19
50580-0449-86 50 POUCH in 1 TRAY (50580-449-86) / 2 TABLET, FILM COATED i... TYLENOL Extra Strength Kenvue Brands LLC 1984-08-19
50580-0449-87 3 POUCH in 1 CARTON (50580-449-87) / 2 TABLET, FILM COATED... TYLENOL Extra Strength Kenvue Brands LLC 1984-08-19
50580-0449-96 1 BOTTLE in 1 CARTON (50580-449-96) / 50 TABLET, FILM COATE... TYLENOL Extra Strength Kenvue Brands LLC 2018-06-25
50580-0449-97 249 TABLET, FILM COATED in 1 PACKAGE, COMBINATION (50580-449... TYLENOL Extra Strength Kenvue Brands LLC 2019-01-28
50580-0449-98 110 TABLET, FILM COATED in 1 PACKAGE, COMBINATION (50580-449... TYLENOL Extra Strength Kenvue Brands LLC 2019-01-28
50580-0451-50 1 BOTTLE, PLASTIC in 1 CARTON (50580-451-50) / 50 TABLET, C... TYLENOL Extra Strength Kenvue Brands LLC 1994-08-19
50580-0451-70 700 TABLET, COATED in 1 BOTTLE, PLASTIC (50580-451-70) TYLENOL Extra Strength Kenvue Brands LLC 1994-08-19
50580-0457-10 1 BOTTLE, PLASTIC in 1 CARTON (50580-457-10) / 100 TABLET,... TYLENOL Extra Strength Kenvue Brands LLC 2020-07-10
50580-0457-11 10 BLISTER PACK in 1 CARTON (50580-457-11) / 10 TABLET, FIL... TYLENOL Extra Strength Kenvue Brands LLC 2020-07-17
50580-0457-70 700 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (50580-457-70) TYLENOL Extra Strength Kenvue Brands LLC 2020-07-17
50580-0472-01 1 BOTTLE in 1 CARTON (50580-472-01) / 24 TABLET, FILM COATE... Tylenol Extra Strength Kenvue Brands LLC 2024-03-18
50580-0472-02 1 BOTTLE in 1 CARTON (50580-472-02) / 50 TABLET, FILM COATE... Tylenol Extra Strength Kenvue Brands LLC 2024-03-18
Observed labelers: Kenvue Brands LLC (86) · Lil' Drug Store Products, Inc. (7) · Select Consumer Group LLC (7) · A-S Medication Solutions (3) · JC World Bell Wholesale Co., Inc. (3) · Jones Healthcare Group - Packaging Services, Inc (3) · +4 more — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.