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Acetaminophen 500 MG Oral Tablet [Tylenol] — RxCUI 209459

Name: Acetaminophen 500 MG Oral Tablet [Tylenol] (RxCUI 209459)
Creator: Brian Staiger, PharmD

RxNorm drug concept · Semantic branded drug

RxCUI 209459 Semantic branded drug · SBD ● Current RxNorm concept 31 FDA products 116 package NDCs Snapshot Jul 14, 2026

This page is curated, coded, and maintained by Dr. Brian Staiger, PharmD

Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI209459

Official nameAcetaminophen 500 MG Oral Tablet [Tylenol]

Concept typeSemantic branded drug (SBD)

RxNorm statusCurrent RxNorm concept

Also known asTylenol 500 MG Oral Tablet; Tylenol Extra Strength 500 MG Oral Tablet; APAP 500 MG Oral Tablet [Tylenol]

FDA products mapped31

Package NDCs mapped116

RxNorm release07/06/2026

Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Acetaminophen Injection: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist

Great question. The IV form is used when you can't take medication by mouth — for example, after surgery, if you're nauseated, or if you need faster, more reliable absorption. It d...
Why am I getting acetaminophen through an IV instead of just taking a pill?
Yes, Acetaminophen Injection is approved for children — for pain relief in kids 2 years and older, and for fever reduction in patients of all ages, including premature newborns bor...
The most important things to watch for are signs of a serious allergic reaction — swelling of your face, mouth, or throat, trouble breathing, or hives — and any new skin rash. Eith...

📖 Read our full Acetaminophen Injection guide →

🕸️ Concept Web — How Acetaminophen 500 MG Oral Tablet [Tylenol] Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.

This page's concept Acetaminophen 500 MG Oral Tablet [Tylenol] RxCUI 209459 Semantic branded drug · SBD

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

Ingredients 1

The active substance itself — no strength, form, or brand attached yet.
- Acetaminophen 161 IN
Brand names 1

The same medicine's trade names. A brand name alone says nothing about strength or form.
- Tylenol 202433 BN
Dose forms 9

The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.
- Acetaminophen Oral Tablet 369097 SCDF
- Acetaminophen Oral Product 1152842 SCDG
- Acetaminophen Pill 1152843 SCDG
- Acetaminophen Oral Tablet [Tylenol] 369070 SBDF
- Tylenol Oral Product 1187311 SBDG
- Tylenol Pill 1187315 SBDG
- Oral Tablet 317541 DF
- Oral Product 1151131 DFG
- +1 more in this family
Clinical & branded drugs 3

Ingredient + strength + dose form. These are the concepts real FDA products actually carry.
- Acetaminophen 500 MG Oral Tablet 198440 SCD
- Acetaminophen 500 MG 315266 SCDC
- Acetaminophen 500 MG [Tylenol] 570070 SBDC

Showing up to 8 concepts per family — 13 of 14 stored related concepts drawn.

These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

Acetaminophen 500 MG Oral Tablet SCD · 198440
Acetaminophen 500 MG SCDC · 315266
Acetaminophen Oral Tablet SCDF · 369097
Acetaminophen Oral Product SCDG · 1152842
Acetaminophen Pill SCDG · 1152843

Brand-Name Concepts

Acetaminophen 500 MG [Tylenol] SBDC · 570070
Acetaminophen Oral Tablet [Tylenol] SBDF · 369070
Tylenol Oral Product SBDG · 1187311
Tylenol Pill SBDG · 1187315
Tylenol BN · 202433

📦 FDA Products & Package NDCs

31 products · 116 package NDCs

116 package NDCs map to RxCUI 209459 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.

Package NDC	Package	Brand / generic name	Labeler	Marketing start
67751-0167-01	1 POUCH in 1 CARTON (67751-167-01) / 2 TABLET, FILM COATED...	Tylenol Extra Strength	Navajo Manufacturing Company Inc.	2016-09-22
67751-0167-02	1 POUCH in 1 CARTON (67751-167-02) / 4 TABLET, FILM COATED...	Tylenol Extra Strength	Navajo Manufacturing Company Inc.	2016-09-22
69968-0711-09	1 KIT in 1 PACKAGE (69968-0711-9) * 1 TUBE in 1 CARTON (69...	Johnson and Johnson All Purpose First Aid Kit	Kenvue Brands LLC	2021-08-16
69968-0726-09	1 KIT in 1 PACKAGE (69968-0726-9) * 1 CLOTH in 1 PACKET *...	Johnson and Johnson First Aid All Purpose 160 CT	Kenvue Brands LLC	2022-01-31
69968-0799-09	1 KIT in 1 PACKAGE (69968-0799-9) * 1 TUBE in 1 CARTON (69...	Johnson and Johnson First Aid Travel Ready 80 CT	Kenvue Brands LLC	2022-01-31
70264-0027-01	50 POUCH in 1 BOX (70264-027-01) / 2 TABLET in 1 POUCH	TYLENOL EXTRA STRENGTH	R J General Corporation	2021-05-01
73097-0012-02	1 POUCH in 1 CARTON (73097-012-02) / 2 TABLET, FILM COATED...	Tylenol Extra Strength	Savings Distributors LLC	2019-07-22
73097-0012-40	20 POUCH in 1 CARTON (73097-012-40) / 2 TABLET, FILM COATED...	Tylenol Extra Strength	Savings Distributors LLC	2019-07-22
73097-0012-50	25 POUCH in 1 BOX (73097-012-50) / 2 TABLET, FILM COATED in...	Tylenol Extra Strength	Savings Distributors LLC	2019-07-22
85237-1946-01	1 POUCH in 1 BLISTER PACK (85237-1946-1) / 2 TABLET, FILM C...	TYLENOL Extra Strength	Select Consumer Group LLC	2025-06-04
85237-1946-02	2 POUCH in 1 BLISTER PACK (85237-1946-2) / 2 TABLET, FILM C...	TYLENOL Extra Strength	Select Consumer Group LLC	2025-06-04
85237-1946-03	20 POUCH in 1 CARTON (85237-1946-3) / 2 TABLET, FILM COATED...	TYLENOL Extra Strength	Select Consumer Group LLC	2025-06-04
85237-1946-04	25 POUCH in 1 CARTON (85237-1946-4) / 2 TABLET, FILM COATED...	TYLENOL Extra Strength	Select Consumer Group LLC	2025-06-04
85237-1946-05	30 POUCH in 1 CARTON (85237-1946-5) / 2 TABLET, FILM COATED...	TYLENOL Extra Strength	Select Consumer Group LLC	2025-06-04
85237-1946-06	50 POUCH in 1 CARTON (85237-1946-6) / 2 TABLET, FILM COATED...	TYLENOL Extra Strength	Select Consumer Group LLC	2025-06-04
85237-1946-07	3 POUCH in 1 BLISTER PACK (85237-1946-7) / 2 TABLET, FILM C...	TYLENOL Extra Strength	Select Consumer Group LLC	2025-06-04

Observed labelers: Kenvue Brands LLC (86) · Lil' Drug Store Products, Inc. (7) · Select Consumer Group LLC (7) · A-S Medication Solutions (3) · JC World Bell Wholesale Co., Inc. (3) · Jones Healthcare Group - Packaging Services, Inc (3) · +4 more — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7

openFDA export observedJul 14, 2026

RxNorm release07/06/2026

Methodology2026-07-full-catalog-v1

A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.

This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.