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Hydrochlorothiazide 25 MG / lisinopril 20 MG Oral Tablet [Zestoretic] — RxCUI 823971

RxNorm drug concept · Semantic branded drug
RxCUI 823971 Semantic branded drug · SBD ● Current RxNorm concept 3 FDA products 3 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI823971
Official nameHydrochlorothiazide 25 MG / lisinopril 20 MG Oral Tablet [Zestoretic]
Concept typeSemantic branded drug (SBD)
RxNorm statusCurrent RxNorm concept
Also known asZestoretic 20/25 Oral Tablet; Zestoretic 20 MG / 25 MG Oral Tablet; HCTZ 25 MG / Lisinopril 20 MG Oral Tablet [Zestoretic]
FDA products mapped3
Package NDCs mapped3
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Lisinopril and Hydrochlorothiazide: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • Great question. Lisinopril is an ACE inhibitor — it relaxes your blood vessels by blocking a chemical in your body that would otherwise make them tighten up. Hydrochlorothiazide is...
  • Why am I taking two medicines in one pill — what does each one do?
  • You can take it either way — with or without food. Food does not affect how your body absorbs lisinopril, so just pick a time of day that's easy for you to remember and stick with...
  • Can I take this pill with food, or does it have to be on an empty stomach?
📖 Read our full Lisinopril and Hydrochlorothiazide guide →

🕸️ Concept Web — How Hydrochlorothiazide 25 MG / lisinopril 20 MG Ora... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Hydrochlorothiazide 25 MG / lisinopril 20 MG Oral Tablet [Zestoretic] RxCUI 823971

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 3

    The active substance itself — no strength, form, or brand attached yet.

    • Hydrochlorothiazide 5487
    • Lisinopril 29046
    • Hydrochlorothiazide / lisinopril 214618
  2. Brand names 1

    The same medicine's trade names. A brand name alone says nothing about strength or form.

    • Zestoretic 85783
  3. Dose forms 9

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Hydrochlorothiazide / lisinopril Oral Tablet 372613
    • Hydrochlorothiazide / lisinopril Oral Product 1162124
    • Hydrochlorothiazide / lisinopril Pill 1162125
    • Hydrochlorothiazide / lisinopril Oral Tablet [Zestoretic] 823970
    • Zestoretic Oral Product 1187277
    • Zestoretic Pill 1187278
    • Oral Tablet 317541
    • Oral Product 1151131
    • +1 more in this family
  4. Clinical & branded drugs 4

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

Showing up to 8 concepts per family — 16 of 17 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

  • Hydrochlorothiazide 25 MG / lisinopril 20 MG Oral Tablet SCD · 197887
  • Hydrochlorothiazide 25 MG SCDC · 316049
  • Lisinopril 20 MG SCDC · 316153
  • Hydrochlorothiazide / lisinopril Oral Tablet SCDF · 372613
  • Hydrochlorothiazide / lisinopril Oral Product SCDG · 1162124
  • Hydrochlorothiazide / lisinopril Pill SCDG · 1162125

Brand-Name Concepts

  • Hydrochlorothiazide 25 MG / lisinopril 20 MG [Zestoretic] SBDC · 823969
  • Hydrochlorothiazide / lisinopril Oral Tablet [Zestoretic] SBDF · 823970
  • Zestoretic Oral Product SBDG · 1187277
  • Zestoretic Pill SBDG · 1187278
  • Zestoretic BN · 85783

📦 FDA Products & Package NDCs

3 products · 3 package NDCs
3 package NDCs map to RxCUI 823971 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
52427-0435-90 90 TABLET in 1 BOTTLE (52427-435-90) Zestoretic Almatica Pharma Inc. 2015-04-15
52427-0436-90 90 TABLET in 1 BOTTLE (52427-436-90) Zestoretic Almatica Pharma Inc. 2015-04-15
52427-0437-90 90 TABLET in 1 BOTTLE (52427-437-90) Zestoretic Almatica Pharma Inc. 2015-04-15
Observed labelers: Almatica Pharma Inc. (3) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.