Can You Split Edarbi Tablets In Half?
In our latest question and answer, our pharmacist discusses whether or not Edarbi tablets can be split in half.
Can I split an Edarbi 40mg in half since it isn't available in a 20mg formulation? What about splitting Edarbyclor (40mg + chlorthalidone 25 mg) in half? My ideal regimen would be 20mg of Azilsartan and 12.5mg of chlorthalidone and neither is available in these dosages!
Last updated Aug 17, 2022
- Edarbi tablets are immediate-release and do not have any type of special coating. They can be cut or split if necessary but this should only be done if directed by your doctor.
- Be sure to use a pill splitter with a sharp blade to ensure tablets are evenly split.
- Edarbyclor tablets are wax-coated, which may make them difficult to split, and will ruin the coating. They can be split if necessary but ideally, should be taken whole.
Hello and thanks for reaching out to us! Even though Edarbi (azilsartan) tablets are not scored, they can safely be split or cut in half.
Splitting Edarbi Tablets
Edarbi tablets are an immediate-release drug formulation, and the drug is rapidly absorbed upon administration. The tablets have no modified/delayed/extended-release characteristics to them so splitting them will not change how the drug is absorbed or released. Additionally, the tablets do not contain any type of wax or film-coating and have not been reported to be irritating to the mouth or throat.
Since Edarbi tablets are not scored, it is highly recommended that you use a pill splitter with a sharp blade to ensure you are splitting the tablets into even halves.
Be sure to talk to your doctor before splitting your Edarbi tablets, however. The recommended dose of the drug is 40mg or 80mg once daily, and Edarbi is available in both of these strengths. It is important not to change the strength or amount of Edarbi you take unless directed to do so by your doctor.
Can You Split Edarbyclor?
Edarbyclor tablets contain two drugs, azilsartan, and chlorthalidone (a diuretic). Edarbyclor, like Edarbi, is an immediate-release formulation but, unlike Edarbi, Edarbyclor tablets are wax-coated. Splitting these tablets will destroy this wax-coating.
Below is an image of both Edarbi (on the left) and Edarbyclor (on the right). You can see the difference in how the tablets look.
If it can be avoided, Edarbyclor should not be split to retain this wax-coating, but they certainly could be if you and your doctor think it represents your best therapy choice. Again, splitting the tablets won't affect how the drug is absorbed or works in your body.
As a final note, the diuretic (chlorthalidone) that is found in edarbyclor can also be taken by itself if there needs to be an adjustment in the dose of this drug only. It is available in dosages of 15mg, 25mg, 50mg, and 100mg.
Thanks again for your question and feel free to reach back out!
- Dr. Brian Staiger, PharmD
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