Can You Split Tramadol Tablets?

In our latest question and answer, the pharmacist discusses whether or not tramadol tablets can be split.

Question

Can I cut tramadol and take one and a half pieces?

Asked by Peter On Dec 20, 2022

Answered by
Medical Content Reviewed By HelloPharmacist Staff

Published Dec 20, 2022
Last updated Apr 27, 2024

Key points

  • Tramadol immediate-release tablets are safe to cut/split. Some have a score mark down the middle of the tablet to facilitate splitting.
  • Extended-release tramadol products should not be cut, split or crushed.

Answer

Yes, most tramadol tablets can safely be cut or split in half. I wrote about this is another answer, which can be found here: Can You Cut Tramadol In Half?

It is important to point out that tramadol is a drug available in many different drug products and dosage forms. They can't all be safely cut in half. Only the immediate-release tablets can safely be split.

So, if you're doctor has instructed you to take one and one-half tablets of tramadol, just make sure you are taking the immediate-release tablets.

Only Split Immediate-Release Tramadol

As mentioned, tramadol comes in many forms, and only the immediate-release tablets can safely be split.

While some tramadol tablets have a score mark down the middle of the tablet to help facilitate splitting, most don't unfortunately. In fact, I don't believe any of the 50mg tablets have a score mark, only the 100mg tablets.

Nevertheless, as long as the tablets are immediate-release, you can split them. Below is an image of two different immediate-release tablets: a tramadol 100mg tablet with a score mark and a tramadol 50mg tablet without a score mark:

Tramadol Tablets With score and without

As a general rule of thumb, you shouldn't split, cut or crush any drug that is extended-release since doing so will cause the entire dose to be released at once, which greatly increases the risk of side effects. Examples of extended-release tramadol products include:

  • ConZip (tramadol extended-release capsules)
  • Ryzolt (tramadol extended-release tablets)
  • Ultram ER (tramadol extended-release tablets)

None of these should be altered from their original form.

Final Words

I hope you found this informative! Reach back out anytime.

References

About the Pharmacist

Dr. Brian Staiger, PharmD

Dr. Brian has been practicing pharmacy for over 13 years and has wide-ranging experiences in many different areas of the profession. From retail, clinical, program development, and administrative responsibilities, he's your knowledgeable and go-to source for all your pharmacy and medication-related questions! Dr. Brian Staiger also has herbalist training and educational certificates in the field of medical ethnobotany. Feel free to send him an email at [email protected]! You can also connect with Dr. Brian Staiger on LinkedIn.

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