Can You Take Collagen With Blood Pressure Medications?
In our latest question and answer, the pharmacist discusses whether or not collagen supplements are safe to take with blood pressure medication.

Question
Can I take Vital Proteins collagen with my blood pressure med (Bystolic)?

Answered by Dr. Brian Staiger, PharmD
Medical Content Reviewed By HelloPharmacist
Staff
Last updated Apr 04, 2025
Key points
- There is no interaction between collagen and blood pressure medication. They are safe to take together.
Answer
Hello and thanks for reaching out to us! We've received a few questions recently regarding collagen peptides and are more than happy to provide some guidance here.
Collagen peptides (including collagen manufactured by Vital Proteins) are safe to take with blood pressure medications. Collagen peptides are not known to affect blood pressure, and there is especially no evidence that it raises blood pressure. You can feel safe taking collagen with Bystolic.
Not only is collagen safe with Bystolic, as mentioned, it doesn't affect blood pressure, and there are no known interactions with any blood pressure medication. This would include:
- Lisinopril
- Ramipril
- Amlodipine
- Enalapril
- Captopril
- Benazepril
- Quinapril
- Losartan
- Valsartan
- Irbesartan
- Doxazosin
- Bisoprolol
- Telmisartan
- Metoprolol
- Propranolol
Remember that collagen is simply a type of protein (which I discuss further in the next section), and is very common in the human diet. Unless protein specifically interacts with your drug (which is uncommon), there is no interaction to be worried about. Be sure to still follow the directions for your specific medication however regarding whether or not it should be taken with food.
What Are Collagen Peptides?
Collagen peptides, also known as hydrolyzed collagen and collagen hydrolysate, are small protein molecules and the primary protein constituent in ligaments, tendons, and skin.
Collagen peptides are generally more absorbable than larger protein molecules (studies suggest collagen peptides are more than 90% absorbable).
A very popular dietary supplement, studies suggest that supplementing with collagen peptides can improve skin hydration and elasticity. They are also used to support wound healing and bone health. It is very well tolerated, and reported side effects from supplementation are generally limited to mild nausea and gas (if they occur at all).
Collagen peptides are soluble in water, and tend to mix easily, unlike gelatin (which is also derived from collagen).
What Is Bystolic?
Bystolic (nebivolol) is used alone or in combination with other medications to treat high blood pressure. Nebivolol is in a class of medications called beta-blockers. It works by relaxing blood vessels and slowing heart rate to improve blood flow and decrease blood pressure.
Final Words
Thanks again for your question! You can feel safe combining collagen peptides and Effexor as they are safe together.
References
- Oral Collagen Supplementation: A Systematic Review of Dermatological Applications, PubMed
- Effects of hydrolyzed collagen supplementation on skin aging: a systematic review and meta-analysis, PubMed
- A Collagen Supplement Improves Skin Hydration, Elasticity, Roughness, and Density: Results of a Randomized, Placebo-Controlled, Blind Study, PubMed
- Bystolic Prescribing Information, AccessFDA
-
Dr. Brian Staiger, PharmD
- 14895 views