Can You Take Delsym If You Have High Blood Pressure?
In our latest question and answer, the pharmacist discusses whether or not it is safe to take Delsym (dextromethorphan) if you have high blood pressure.
Question
Can I take Delsym cough if I have high blood pressure and currently take amlodipine and metoprolol?
Answered by Dr. Brian Staiger, PharmD
Medical Content Reviewed By HelloPharmacist
Staff
Last updated Jan 15, 2025
Key points
- Delsym (dextromethorphan) is not known to increase blood pressure and is considered safe for those that have high blood pressure (i.e. hypertension).
Answer
Dextromethorphan (Delsym) does not generally cause or worsen high blood pressure. In addition, there are no drug interactions between dextromethorphan, amlodipine, and metoprolol.
In fact, dextromethorphan is an ingredient in many of the 'Coricidin HBP' products, which are cough/cold medications formulated to be safe to use in those with high blood pressure.
Watch Out For Combination Cough/Cold Products
It is important to be wary of combination ingredient cold and cough products that contain dextromethorphan, as it is a common component in many multi-ingredient formulas. Products containing phenylephrine or pseudoephedrine may increase blood pressure and should generally be avoided in patients with high blood pressure.
Be sure to always read the labels of the product you are looking to take!
What Is Dextromethorphan?
Dextromethorphan (commonly referred to as DM on many over-the-counter products) is a cough suppressant that reduces the urge to cough. It is best to prevent a bothersome dry cough or a cough that doesn’t involve mucus from the lower respiratory system.
Dextromethorphan should not be used to treat chronic cough, including cough related to asthma or COPD. If the cough lasts for more than one week or is associated with more severe symptoms such as nausea, vomiting, and fever, it is recommended to see a physician.
OTC Cough Expectorant - Guaifenesin
Another product that works against cough is Guaifenesin (Mucinex), which is also safe if you have high blood pressure.
Guaifenesin is a cough expectorant that helps break down mucus in the upper and lower airway. Guaifenesin loosens phlegm and secretions which can then be expelled. Guaifenesin is best used to reduce the symptoms of having a deep cough that can’t be cleared.
Although many products contain both dextromethorphan and guaifenesin, it may be best to pick the single ingredient that will help based on the type of cough that you have. Taking several medications when one may be sufficient could lead to unnecessary side effects or risks.
Final Words
All in all, dextromethorphan is unlikely to cause an increase in high blood pressure and does not have any drug interactions with amlodipine or metoprolol. Always be careful to read all active ingredients when selecting OTC products, as products with phenylephrine or pseudoephedrine may cause an increase in blood pressure.
- Dr. Brian Staiger, PharmD
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